检索结果-南通市图书馆

Lipid transport to avian oocytes and to the developing embryo

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

The journal of Biomedical Research 2016年第3期30卷 174-180页

作者： Wolfgang j.schneider Department of Medical Biochemistry Max F.Perutz LaboratoriesMedical University and Biocenter Vienna

Studies of receptor-mediated lipoprotein metabolic pathways in avian species have revealed that physiological intricacies of specific cell types are highly analogous to those in mammals. A prime example for the power of com- parative studies across different animal kingdoms, elucidated in the chicken, is that the expression of different lipo- protein receptors in somatic cells and oocytes are the key to oocyte growth. In avian species, yolk precursor transport from the hen＇s liver to rapidly growing oocytes and the subsequent transfer of yolk nutrients via the yolk sac to the developing embryo are highly efficient processes. Oocytes grow from a diameter of 5 mm to 2.5-3 cm in only 7 days, and the yolk sac transfers nutrients from the yolk stored in the mature oocyte to the embryo within just 2 weeks. The underlying key transport mechanism is receptor-mediated endocytosis of macromolecules, i.e., of hepatically synthesized yolk precursors for oocyte growth, and of mature yolk components for embryo nutrition, respectively. Recently, the receptors involved, as well as the role of lipoprotein synthesis in the yolk sac have been identified. As outlined here, lipoprotein degradation/resynthesis cycles and the expression of lipoprotein receptors are not only coordinated with the establishment of the tbllicular architecture embedding the oocyte, but also with the generation of the yolk sac vasculature essential for nutrient transfer to the embryo.

关键词： chicken embryo oocyte yolk sac lipoprotein receptors vascularization

Origin and fate of the nucleolar channel system of normal human endometrium

在线全文

学校读者我要写书评

暂无评论

Cell Research 1992年第2期2卷 97-102页

作者： j schneider Department of Gynecology and Obstetrics Medical College of Jinan University Guangzhou China Frauenklinik der Medizinischen Hochschule Hannover Germany

Human normal endometrium was examined in *** channel system(NCS)appeared in theendometrial epithelial cells during the early and mid secre-tory phase of menstrual *** NCS was a hollow balllike structure of different sizes and was composed of 2 to 5rows of tubules embedded in an amorphous *** itssurface there were numerous electron dense particles resem-bling *** was usually located within or associatedwith the ***,it was close to the nuclearenvelope or protruding out from the *** occasion,NCS with simplified structure was found in the *** concerning the genesis,involution andfunction(s) of the NCS were discussed.

关键词： nucleolar channel system human endometrial epithelium secretory phase.

Disparities in chiropractic utilization by race,ethnicity and socioeconomic status:A scoping review of the literature

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

journal of Integrative Medicine 2023年第2期21卷 159-167页

作者： jordan A.Gliedt Antoinette L.Spector Michael j.schneider joni Williams Staci Young Department of Neurosurgery Medical College of WisconsinMilwaukeeWI 53226USA Department of Rehabilitation Sciences and Technology University of Wisconsin-MilwaukeeMilwaukeeWI 53201USA Department of Physical Therapy University of PittsburghPittsburghPA 15219USA Clinical and Translational Science Institute University of PittsburghPittsburghPA 15213USA Department of Medicine Division of Internal MedicineMedical College of WisconsinMilwaukeeWI 53226USA Department of Family and Community Medicine Medical College of WisconsinMilwaukeeWI 53226USA

Background Chiropractic is the largest complementary and alternative medicine profession in the United States,with increasing global growth.A preliminary literature review suggests a lack of widespread diversity of chiropractic patient *** There have been no prior studies to comprehensively integrate the literature on chiropractic utilization rates by race,ethnicity,and socioeconomic *** purpose of this scoping review is to identify and describe the current state of knowledge of chiropractic utilization by race,ethnicity,education level,employment status,and income and poverty *** strategy Systematic searches were conducted in PubMed,Ovid MEDLINE,Cumulative Index of Nursing and Allied Health Literature(CINAHL),Cochrane Database of Systematic Reviews,and Index to Chiropractic Literature from inception to May *** criteria Articles that reported race or ethnicity,education level,employment status,income or poverty level variables and chiropractic utilization rates for adults(≥18 years of age)were eligible for this *** extraction and analysis Data extracted from articles were citation information,patient characteristics,race and ethnicity,education level,employment status,income and poverty level,and chiropractic utilization rate.A descriptive numerical summary of included studies is *** study provides a qualitative thematic narrative of chiropractic utilization with attention to race and ethnicity,education level,income and poverty level,and employment *** A total of 69 articles were eligible for *** articles were published since 2003 and reported data from study populations in the United *** the race,ethnicity and socioeconomic categories that were most commonly reported,chiropractic utilization was the highest for individuals identifying as European American/White/non-Hispanic White/Caucasian(median 20.00%;interquartile range 2.70%-64.60%),those with employment as a main income sourc

关键词： Chiropractic Utilization Health inequities Health disparities Low-back pain Neck pain

Current landscape in motoneuron regeneration and reconstruction for motor cranial nerve injuries

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第9期15卷 1639-1649页

作者： Yanjun Xie Kevin j.schneider Syed A.Ali Norman D.Hogikyan Eva L.Feldman Michael j.Brenner Department of Otolaryngology-Head and Neck Surgery University of Michigan Medical SchoolAnn ArborMIUSA Department of Neurology University of Michigan Medical SchoolAnn ArborMIUSA

The intricate anatomy and physiology of cranial nerves have inspired clinicians and scientists to study their roles in the nervous system. Damage to motor cranial nerves may result from a variety of organic or iatrogenic insults and causes devastating functional impairment and disfigurement. Surgical innovations directed towards restoring function to injured motor cranial nerves and their associated organs have evolved to include nerve repair, grafting, substitution, and muscle transposition. In parallel with this progress, research on tissue-engineered constructs, development of bioelectrical interfaces, and modulation of the regenerative milieu through cellular, immunomodulatory, or neurotrophic mechanisms has proliferated to enhance the available repertoire of clinically applicable reconstructive options. Despite these advances, patients continue to suffer from functional limitations relating to inadequate cranial nerve regeneration, aberrant reinnervation, or incomplete recovery of neuromuscular function. These shortfalls have profound quality of life ramifications and provide an impetus to further elucidate mechanisms underlying cranial nerve denervation and to improve repair. In this review, we summarize the literature on reconstruction and regeneration of motor cranial nerves following various injury patterns. We focus on seven cranial nerves with predominantly efferent functions and highlight shared patterns of injuries and clinical manifestations. We also present an overview of the existing reconstructive approaches, from facial reanimation, laryngeal reinnervation, to variations of interposition nerve grafts for reconstruction. We discuss ongoing endeavors to promote nerve regeneration and to suppress aberrant reinnervation and the development of synkinesis. Insights from these studies will shed light on recent progress and new horizons in understanding the biomechanics of peripheral nerve neurobiology, with emphasis on promising strategies for optimizing

关键词： axon degeneration cranial neuropathy facial nerve facial paralysis motoneuron nerve regeneration peripheral nerve recurrent laryngeal nerve synkinesis vocal fold paralysis

High-yield synthesis and liquid-exfoliation of two- dimensional belt-like hafnium disulphide

在线全文

学校读者我要写书评

暂无评论

Nano Research 2018年第1期11卷 343-353页

作者： Harneet Kaur Sandeep Yadav Avanish K. Srivastava Nidhi Singh Shyama Rath jorg j. schneider Om P. Sinha Ritu Srivastava National Physical Laboratory Council of Scientific and Industrial Research Dr. K. S. Krishnan Road New Delhi I I O012 India Academy of Scientific and Innovative Research NPL New Delhi 110012 India Technische Universitat Darmstadt Eduard-ZintMnstitut f~r Anorganische und Physikalische Chemie 12 105 117 Alarich-Weiss-Str 12 64287 Darmstadt Germany DepartmentofPhysics andAstrophysics University of Delhi Delhi 110007 India Amity Institute of Nanotechnology Amity University UP Sector 125 Noida Uttar Pradesh 201313 India

Producing environmentally stable monolayers and few-layers of hafnium disulphide （HfS2） with a high yield to reveal its unlocked electronic and optoelectronic applications is still a challenge. HfS2 is a layered two-dimensional material of group-IV transition metal dichalcogenides. For the first time, we demonstrate a simple and cost-effective method to grow layered belt-like nanocrystals of HfS2 with a notably large interlayer spacing followed by their chemical exfoliation. Various microscopic and spectroscopic techniques confirm that these as-grown crystals exfoliate into single or multiple layers in a few minutes using solvent assisted ultrasonification method in N-cyclohexyl-2- pyrrolidone. The exfoliated nanosheets of HfS2 exhibit an indirect bandgap of 1.3 eV with high stability against surface degradation. Furthermore, we demonstrate that these nanosheets hold potential for electronic applications by fabricating a field-effect transistor based on few-layered HfS2, exhibiting a field-effect mobility of 0.95 cm2/（V.s） with a high on/off current modulation ratio of 10,000 in ambient conditions. The method is scalable and has a potential significance for both academic and industrial purposes.

关键词： two-dimensionalmaterials hafnium disulphide nano-crystals liquid-phase exfoliation environment-stabili~ field-effect transistor

Thixocasting combination spanners using stainless steel X39CrMo17

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国有色金属学会会刊：英文版 2010年第S3期20卷 998-1004页

作者： M.BüNCK E.SUBASIC A.BüHRIG-POLACZEK K.jIANG S.MüNSTERMANN j.M.schneider K.FICKERT H.j.GüNTHER Foundry Institute at RWTH Aachen University AachenGermany Materials Chemistry at RWTH Aachen University AachenGermany HAZET-Hermann Zerver GmbH & Co.KG RemscheidGermany PlaTeG GmbH SiegenGermany

Forging is state-of-the-art for producing hand tools on an industrial *** to high demands on the stiffness and the fracture toughness,high-strength forging steels were used to provide cavity-free components with high mechanical load ***,forging is a cost-effective mass production process but,in spite of all its advantages,it has its limitations,*** the freedom of ***,because of the extreme thermal loading(particularly with regard to permanent moulds) and the frequently unavoidable casting defects,hand tools are not *** means of thixocasting steel,technical difficulties can be reduced and new options are provided which allow the manufacturing of components with much higher complexity than that using *** near-net shape production,manufacturing steps and costs can be ***,steels,which are difficult to forge but nonetheless have high potential for specific applications(such as high strength or corrosion resistant steels),can also be *** cooperation with industrial partners,X39CrMo17 stainless steel combination spanners with 17 mm width across flats were *** dies were designed and optimized by simulation,the hot forming X38CrMoV5 tool steel as well as the molybdenum alloy TZM were selected as the tool *** dies were treated by a plasma nitriding process and subsequently coated with crystalline Al2O3 protective coatings by plasma-enhanced chemical vapor deposition(PECVD).During the experiments,combination spanners were successfully cast in the semi-solid *** parts were heat-treated to enhance the toughness of components,which was subsequently measured by a standardized torque ***,a hypothetical approach of a possible,industrial batch process was carried out using the simulation software MAGMAsoft.

关键词： thixocasting X39CrMo17 steel casting semi-solid MAGMAsoft simulation

APPROXIMATING THE STATIONARY BELLMAN EQUATION BY HIERARCHICAL TENSOR PRODUCTS

在线全文

学校读者我要写书评

暂无评论

journal of Computational Mathematics 2024年第3期42卷 638-661页

作者： Mathias Oster Leon Sallandt Reinhold schneider Technische Universität Berlin Strasse des 17.Juni 13510623 BerlinGermany

We treat infinite horizon optimal control problems by solving the associated stationary Bellman equation numerically to compute the value function and an optimal feedback *** dynamical systems under consideration are spatial discretizations of non linear parabolic partial differential equations(PDE),which means that the Bellman equation suffers from the curse of *** non linearity is handled by the Policy Iteration algorithm,where the problem is reduced to a sequence of linear equations,which remain the computational bottleneck due to their high *** reformulate the linearized Bellman equations via the Koopman operator into an operator equation,that is solved using a minimal residual *** the Koopman operator we identify a preconditioner for operator equation,which deems essential in our numerical *** overcome computational infeasability we use low rank hierarchical tensor product approximation/tree-based tensor formats,in particular tensor trains(TT tensors)and multi-polynomials,together with high-dimensional quadrature,*** controlling a destabilized version of viscous Burgers and a diffusion equation with unstable reaction term numerical evidence is given.

关键词： Feedback control Dynamic programming Hamilton-jacobi-Bellman Tensor product approximation Variational Monte-Carlo

Modeling displacement flow inside a full-length casing string for well cementing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Petroleum Research 2024年第1期9卷 1-16页

作者： Hu Dai Ali Eslami jason schneider Gefei Liu Fred Schwering Pegasus Vertex Inc.USA Laval University Canada Sanjel Energy Services Canada Athabasca Oil Corporation Canada

While computer modeling of annular displacement efficiency is widely applied in cementing engineering,modeling the displacement flow inside a casing or drill string for cementing operations has received less *** predicting displacement efficiency inside a full-length pipe is desired by cementing engineers,the attempt of developing a model with both efficiency and accuracy faces *** to computer simulators for this purpose is *** with annular flow,the displacement flow inside pipe,although within a simpler geometry and without eccentricity effect,is not simpler in physics,modelling strategy and predictability,because a variety of flow patterns and flow instabilities can develop to create complicated fluid *** this paper,we present an integrated numerical model developed to simulate displacement flows inside a full-length pipe,which connects an existing annulus model to enable complete displacement simulations of cementing *** model uses three-dimensional grid to solve fluid concentrations with degrees of mixing,and incorporates flow instability detection and flow regime *** in cementing,the model accounts for effects of pumping rate,well inclination,pipe rotation,fluid densities,rheological parameters and *** computationally efficient model does not rely on high-resolution mesh as often required by conventional Computational Fluid Dynamics models,thus it is suitable to be implemented in a cementing software for daily use by well cementing *** methodology of the model is discussed in detail in this *** validate the model,we examine simulation results against experimental results obtained in our laboratory tests and CFD simulations;acceptable agreement is found under different testing *** also presented two case studies of real cementing jobs with cement evaluation logs compared to simulation results,showing that the model can predict consistent displacement efficie

关键词： Inside pipe displacement Displacement efficiency Numerical model Primary cementing Displacement flow

Two-photon emission from a superlattice-based superconducting light-emitting structure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第7期13卷 1331-1340页

作者： Shlomi Bouscher Dmitry Panna Ronen jacovi Fauzia jabeen Christian schneider Sven Höfling Alex Hayat Department of Electrical Engineering TechnionHaifa 32000Israel. Technische Physik Universität WürzburgAm HublandD-97074 WürzburgGermany. Institute of Physics Carl von Ossietzky Universität OldenburgD-26111 OldenburgGermany

Superconductor-semiconductor hybrid devices can bridge the gap between solid-state-based and photonics-based quantum systems,enabling new hybrid computing schemes,offering increased scalability and *** example for a hybrid device is the superconducting light-emitting diode(SLED).SLEDs have been theoretically shown to emit polarization-entangled photon pairs by utilizing radiative recombination of Cooper ***,the twophoton nature of the emission has not been shown experimentally *** demonstrate two-photon emission in a GaAs/AlGaAs *** electroluminescence spectra reveal unique two-photon superconducting features below the critical temperature(Tc),while temperature-dependent photon-pair correlation experiments(g(2)(τ,T))demonstrate temperature-dependent time coincidences below Tc between photons emitted from the *** results pave the way for compact and efficient superconducting quantum light sources and open new directions in light-matter interaction studies.

关键词： photon quantum utilizing