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阿基坦创意经济与文化中心

城市环境设计 2019年第2期118卷 74-83页

作者： Alexander Codda Alicia Marie Sarah Borhardt Annette Birthe Jensen ?smund Skeie Aya Fibert Bartosz Kobylakiewicz Bernhard Touzet Brigitta Gulyás David Tao Edouard Champelle Espen Vik Greta Krenciute Greta Tafel Hyojin Lee ivan genov Jan Magasanik Jeffrey Mark Mikolajewski Karol Bogdan Borkowski Katarzyna Swiderska Kekoa Charlot Lorenzo Boddi Maria Teresa Fernandez Rojo Melissa Andres Michael Sch?nemann Jensen Nicolas Millot Ola Hariri Ole Dau Mortensen Pascale Julien Paul-Antoine Lucas Raphael Ciriani Santiago Palacio Villa Se Hyeon Kim Sebastian Liszka Seunghan Yeum Snorre Emanuel Nash J?rgensen Teresa Fernández Thiago De Almeida Thomas Jakobsen Randb?ll Yang Du Zoltan David Kalaszi ivan Mata Laurent de Carniere 朱翰林

这栋建筑将三个文化机构融入其中:FRAC(阿基坦区当代艺术基金会)、ECLA(写作、音乐、电影和广播文化机构)和OARA(阿基坦区行为艺术家工作室)。现在它们被共同整合为阿基坦创意经济与文化中心,即MéCA文化中心。我们希望设计一栋可以将... 详细信息

这栋建筑将三个文化机构融入其中:FRAC(阿基坦区当代艺术基金会)、ECLA(写作、音乐、电影和广播文化机构)和OARA(阿基坦区行为艺术家工作室)。现在它们被共同整合为阿基坦创意经济与文化中心,即MéCA文化中心。我们希望设计一栋可以将波尔多滨水步道整合其中的建筑,允许公众生活路线从中穿过。

关键词：阿基坦波尔多城市客厅经济与文化

REGULARITY FOR A GENERALIZED JEFFREY'S INTEGRAL MODEL FOR VISCOELASTIC FLUIDS

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Acta Mathematica Scientia 2015年第6期35卷 1251-1284页

作者： ivan SOUKUP Department of Numerical Mathematics Faculty of Mathematics and PhysicsCharles University in Prague

We prove a local existence of a strong solution v ：Ω×T→R^3 for a system of nonlinear integrodifferential equations describing motion of an incompressible viscoelastic fluid using standard mathematical tools. The problem is considered in a bounded, smooth domain ΩСR^3 with a Dirichlet boundary condition and a standard initial condition.

关键词： integral model viscoelastic fluid strong solution

Topology of Moment-Angle Manifolds Arising from Flag Nestohedra

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Chinese Annals of Mathematics,Series B 2017年第6期38卷 1287-1302页

作者： ivan LIMONCHENKO School of Mathematical Sciences Fudan UniversityShanghai 200433China.

The author constructs a family of manifolds, one for each n ≥ 2, having a nontrivial Massey n-product in their cohomology for any given n. These manifolds turn out to be smooth closed 2-connected manifolds with a compact torus Tm-action called momentangle manifolds ZP, whose orbit spaces are simple n-dimensional polytopes P obtained from an n-cube by a sequence of truncations of faces of codimension 2 only(2-truncated cubes). Moreover, the polytopes P are flag nestohedra but not graph-associahedra. The author also describes the numbers β^(-i,2(i+1))(Q) for an associahedron Q in terms of its graph structure and relates it to the structure of the loop homology(Pontryagin algebra)H_*(?ZQ), and then studies higher Massey products in H*(ZQ) for a graph-associahedron Q.

关键词： Moment-angle manifold Flag nestohedra Stanley-Reisner ring Masseyproducts Graph-associahedron

From neurogenesis to neuronal regeneration: the amphibian olfactory system as a model to visualize neuronal development in vivo

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Neural Regeneration Research 2015年第6期10卷 872-874页

作者： ivan Manzini Institute of Neurophysiology and Cellular Biophysics University of Gottingen Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB)

How do individual neurons develop and how are they in- tegrated into neuronal circuitry？ To answer this question is essential to understand how the nervous system develops and how it is maintained during the adult life. A neural stem cell must go through several stages of maturation, including proliferation, migration, differentiation, and integration, to become fully embedded to an existing neuronal circuit. The knowledge on this topic so far has come mainly from cell culture studies. Studying the development of individual neurons within intact neuronal networks in vivo is inherently difficult. Most neurons are generated form neural stem cells during embryonic and early postnatal development.

关键词： the amphibian olfactory system as a model to visualize neuronal development in vivo Figure

Experimental and calculated liquid-liquid interfacial tension in demixing metal alloys

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Rare Metals 2006年第5期25卷 452-456页

作者： Walter Hoyer ivan Kaban Institute of Physics Chemnitz University of Technology D-09107 ChemnitzGermany

Liquid-liquid interracial tension in binary and temary Al-based monotectic systems has been determined experimentally with a tensiometric method in a wide temperature interval. The temperature dependence of the interfacial tension is well described by a power law function of the type σαβ - （1 - T/Tc）δ with the critical exponent δ= 1.3 and a critical temperature Tc. Theoretical models describing the liquid-liquid interface in monotectic alloys and their applicability for calculation of the interfacial tension and its temperature dependence in binary systems are considered.

关键词： immiscible systems Al-based alloys interracial tension

Effects of pre-existing cracks and infillings on strength of natural rocks--Cases of sandstone, argillite and basalt

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Journal of Rock Mechanics and Geotechnical Engineering 2020年第6期12卷 1333-1338页

作者： Chen Cui ivan Gratchev School of Engineering Griffith UniversityGold CoastAustralia

This study aims to examine the influence of pre-existing discontinuities on the strengths of four natural rocks of different origins.A series of unconfined compression tests was performed on specimens of two types of sandstones,argillite and basalt that contain open and filled *** was found that the presence of cracks tends to decrease the overall strength for all studied rocks;however,the magnitude of strength reduction is related to the property of *** larger strength decrease was observed for the relatively harder argillite and basalt,compared to the softer *** was also found that the infill material could increase the strength of rock specimens,while the obtained strength depended on the characteristics of the fill material.

关键词： Pre-existing crack Rock strength Infill material Laboratory test

Purinergic Modulation of Activity in the Developing Auditory Pathway

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Neuroscience Bulletin 2020年第11期36卷 1285-1298页

作者： Sasa Jovanovic ivan Milenkovic School of Medicine and Health Sciences Carl von Ossietzky University Oldenburg26129 OldenburgGermany

Purinergic P2 receptors,activated by endogenous ATP,are prominently expressed on neuronal and nonneuronal cells during development of the auditory periphery and central auditory *** the mature cochlea,extracellular ATP contributes to ion homeostasis,and has a protective function against noise ***,we focus on the modulation of activity by extracellular ATP during early postnatal development of the lower auditory *** mammals,spontaneous patterned activity is conveyed along afferent auditory pathways before the onset of acoustically evoked signal *** this critical developmental period,inner hair cells fire bursts of action potentials that are believed to provide a developmental code for synaptic maturation and refinement of auditory circuits,thereby establishing a precise tonotopic *** ATP-release triggers such patterned activity by raising the extracellular K+concentration and contributes to firing by increasing the excitability of auditory nerve fibers,spiral ganglion neurons,and specific neuron types within the auditory brainstem,through the activation of diverse P2 *** review recent studies that provide new models on the contribution of purinergic signaling to early development of the afferent auditory ***,we discuss potential future directions of purinergic research in the auditory system.

关键词： Purinergic signaling Auditory system Development Cochlea Spiral ganglion Auditory brainstem

Recent Breakthroughs in the Characterization of Abscisic Acid Efflux Transporters: Shedding New Light on Abscisic Acid Dynamics and Regulation

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Phyton-International Journal of Experimental Botany 2024年第11期93卷 2707-2714页

作者： ivan Couee UMR 6553 Ecosystems-Biodiversity-Evolution University of Rennes/CNRSCampus de Beaulieubatiment 14ARennesF-35042France

The 15-carbon terpenoid abscisic acid(ABA)acts in vascular plants as a versatile hormone playing essential roles in reproductive development,vegetative development and growth,stress-development interactions,and physio-logical responses to abiotic and biotic *** the past 60 years,ABA dynamics,regulation,and responses have been progressively characterized:synthesis,transport and translocation,conjugation and deconjugation,metabolism,sensing,signal transduction,and downstream *** this context,the discovery of ABA expor-ters and importers has added novel dimensions to the understanding of ABA ***,since the initi-al discovery of the adenosine triphosphate-binding cassette(ABC)AtABCG25 exporter and AtABCG40 importer,several transporters of ABA have been *** ABA is synthesized within cells,efﬂux transport of ABA to extracellular spaces is an important controlling step before ABA movements from cell to cell and from source to *** now,structural and functional mechanistic interactions between ABA and its transporters have remained poorly *** structure-function studies have unveiled key features of the mechanisms and functional dynamics of ABA-transporter interactions in the case of the ABCG25 ***25 has been established as a bonaﬁde ABA efﬂux transporter involved in signal transmission leading to stomatal *** has also been shown to transport ABA-glucosyl ester(ABA-GE)conjugated form,thus implying involvement in conjugation and deconjugation *** of these mechanisms are essential for distribution throughout source tissues,source-to-target transmission,distribution throughout target tissues,and signal shape kinetics in target *** opinion piece emphasizes the pivotal role of transport discoveries in the history of ABA research,and how recent studies on ABA and ABA-GE transporters yield a more integrative vision of ABA reg-ulation and adaptive responses,open new avenues of resea

关键词： ABA abiotic stress hormone homeostasis hormone signaling stomatal regulation translocation

Dry powder platform for pulmonary drug delivery

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Particuology 2008年第4期6卷 225-238页

作者： Derek ivan Daniher Jesse Zhu Graduate Program in Biomedical Engineering Department of Chemical and Biochemical EngineeringThe University of Western OntarioLondonOntarioCanada

The phenomenon of particle interaction involved in pulmonary drug delivery belongs to a wide variety of disciplines of particle technology, in particular, fluidization. This paper reviews the basic concepts of pulmonary drug delivery with references to fluidization research, in particular, studies on Geldart group C powders. Dry powder inhaler device-formulation combination has been shown to be an effective method for delivering drugs to the lung for treatment of asthma, chronic obstructive pulmonary disease and cystic fibrosis. Even with advanced designs, however, delivery efficiency is still poor mainly due to powder dispersion problems which cause poor lung deposition and high dose variability. Drug particles used in current inhalers must be 1–5 μm in diameter for effective deposition in small-diameter airways and alveoli. These powders are very cohesive, have poor flowability, and are difficult to disperse into aerosol due to cohesion arising from van der Waals attraction. These problems are well known in fluidization research, much of which is highly relevant to pulmonary drug delivery.

关键词： Dry powder inhaler Interparticle forces Aerosol Pulmonary drug delivery Carrier particle Fluidization