检索结果-南通市图书馆

沈阳药科大学学报 2008年第S1期25卷 15-15页

作者： FENG Wan-yu,LIU Yang,ZHANG Zhi-cheng(The first affiliated hospital,china medical university,shenyang 110001,china)

Objective To discuss mechanism of BH3 domain counterpart BH3I-2' inducing colorectal cancer cell *** Detected inhibition ratio and apoptosis of colorectal cancer cells HCT-116,which were treated by BH3I-2',with microplate reader and flow *** Inhibition ratio of colorectal cancer cells,which were treated by BH3I-2',could reach about 50%.Ratio of viable apoptotic cell decreased and that of non-viable apoptotic cell increased as time *** BH3I-2' can induce colorectal cancer cell apoptosis.

关键词： BH3I-2’ apoptosis colorectal cancer cells flow cytometry

Clinical characteristics of triple negative breast cancer in northeast Chinese patients

在线全文

学校读者我要写书评

暂无评论

Clinical characteristics of triple negative breast cancer in...

麻醉前应用戊乙奎醚对冠脉搭桥术患者血流动力学和脑电双频指数的影响

国际药理学术研讨会暨第三届两岸三地药理学学术会议

作者： Jie Ren,Zhao-Jin Yu,Lin Zhao,Feng Jin,Hai-Shan Zhao 1,Wei-Fan Yao, Min-Jie Wei~* Department of Pharmacology,Pharmaceutical College of china medical university, first affiliated hospital of china medical university,shenyang 1100011, china shenyang 110001 china

＜正＞Aim:Triple-negative breast cancer（TNBC）is defined by a lack of expression of estrogen receptor, progesterone receptor,and human epidermal growth factor receptor2（HER2）,which has a relatively aggressive clini... 详细信息

关键词： Triple -Negative Breast Cancer Clinical characteristics BRCA1

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

中国新药与临床杂志 2011年第9期30卷 667-669页

作者：方波马虹中国医科大学附属第一医院麻醉科辽宁沈阳110001

目的观察冠脉搭桥术麻醉前应用戊乙奎醚对麻醉诱导前后患者血流动力学和脑电双频指数(BIS)的影响。方法择期全麻下行冠脉搭桥术患者40例,随机分为2组,每组20例。戊乙奎醚组麻醉诱导前肌内注射(肌注)戊乙奎醚0.01 ***-1,东莨菪碱组肌注... 详细信息

目的观察冠脉搭桥术麻醉前应用戊乙奎醚对麻醉诱导前后患者血流动力学和脑电双频指数(BIS)的影响。方法择期全麻下行冠脉搭桥术患者40例,随机分为2组,每组20例。戊乙奎醚组麻醉诱导前肌内注射(肌注)戊乙奎醚0.01 ***-1,东莨菪碱组肌注东莨菪碱0.006 ***-1。观察比较2组麻醉诱导前后心率、血压、心率收缩压乘积(RPP)和BIS值。结果东莨菪碱组用药后收缩压和RPP无明显变化,用药后20 min患者心率有所上升,用药后10、20 min BIS值有所下降,但高于戊乙奎醚组(P<0.05)。戊乙奎醚组用药后10、20 min,患者心率、血压、RPP和BIS值均降低(P<0.05)。气管插管前后戊乙奎醚组心率、收缩压、RPP和BIS值多低于东莨菪碱组。2组均未见明显不良反应。结论应用戊乙奎醚作为冠脉搭桥术前用药,可降低心肌耗氧量,有利于患者血流动力学平稳和镇静。

关键词：戊乙奎醚东莨菪碱冠状动脉分流术血流动力学脑电双频指数

Prevention of grafted liver from reperfusive injury

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2001年第4期7卷 572-574页

作者： Kai Ma Yang Yu Xian-Min Bu Yan-Jun Li Xian-Wei Dai Liang Wang Yang Dai Hai-Ying Zhao Xiang-Hong Yang Department of General Surgery,Second Clinical College,china medical university,shenyang 110003,Liaoning Province,chinaDepartrnent of Physiology,shenyang Physical Education College,shenyang,Liaoning Province,chinaDepartment of Pathology,china medical university,shenyang,Liaoning Province,china Department of General Surgery Second Clinical College China Medical University Shenyang 110003 Liaoning Province China.

INTRODUCTIONThe incidence of primary non-function(PNF)of grafted liver in the early postoperative stage is 2%-23%[1-4],its main cause is the ischemic-rechemic injure[5,6].In this experiment,anisodamine was added into the preserving fluid and the grafted liver was rewarmed at different temperatures to protect the cell membranc and prevent ischemic-reperfusive injury.

关键词： Liver Transplantation Animals Body Temperature Drugs, Chinese Herbal Free Radical Scavengers Hepatocytes Lipid Peroxidation Liver Male Microscopy, Electron Rats Rats, Wistar Reactive Oxygen Species Reperfusion Injury control Research Support, Non-U.S. Gov't Solanaceous Alkaloids Superoxide Dismutase

Bacteriological and electron microscopic examination of primary intrahepatic stones

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2006年第2期5卷 228-231页

作者： Shuo-Dong Wu, Hong Yu and Ji-Mei Sun Department of General Surgery Department of Microbiology Center Second affiliated Hos- pital china medical university, shenyang 110004, china Department of General Surgery Second Affiliated Hospital (Shengjing Hospital) China Medical University Shenyang 110004 China. wushuodong@***

BACKGROUND: Primary intrahepatic cholelithiasis is usually combined with biliary tract infection. This research was undertaken to investigate the relationship between intrahepatic stones and biliary tract infection. METHODS: Thirty-five bile samples and 30 stones specimens were cultured for bacteria and 12 stones specimens were examined with a scan electron microscope (SEM) or a transmission electron microscope (TEM). RESULT: 94.2% bile samples and 96.7% stones specimens were positive in bacteria culture. Bacteria were found in stones under SEM and TEM. CONCLUSION: Bacteria in stones are associated with the infection of the biliary tract.

关键词： cholelithiasis bacteria scan electron microscope transmission electron microscope biofilm

Studies on mechanism of Sialy Lewis-X antigen in liver metastases of human colorectal carcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2001年第3期7卷 425-430页

作者： Xiao Wei Li~1 Yan Qing Ding~1 Jun Jie Cai~1 Shao Qing Yang~2 Lian Bing An~3 Dong Fang Qiao~3 ~1Department of Pathology,Nanfang hospital of the first Military medical university,Guangzhou 510515,Guangdong Province,china ~2The Northern hospital of PLA,shenyang 110015,Liaoning Province,china ~3Department of Electronmicroscopy,first Military medical university,Guangzhou 510515,Gangdong Province,chinaDr.Xiao Wei Li graduated from the first Military medical university with a MM degree in 1999.Physician in Charge of pathology,having 6 papers published. Department of Pathology Nanfang Hospital of the First Military Medical University Tonghe Guangzhou 510515 Guangdong Province China.

INTRODUCTIONSialyl Lewis-X antigen ,correlated with carcinoma, is a group of carbohydrate antigen containing oligosaccharide expressed of embryonic tisue and glycoproteins on cell surface of embryonic tissue[1].The SLeX antigen located on cell surface is synthesized principally by two enzymes ,al ,3fucosyltransfrease and a2, *** adults ,SLeX antigen is expressed principally on the surfaces of granulocytic cells and some tumor cells .

关键词： Animals Antibodies, Monoclonal Antigens, CD15 Cell Adhesion Colorectal Neoplasms E-Selectin Endothelium, Vascular Flow Cytometry HT29 Cells Humans Immunohistochemistry In Situ Hybridization Liver Neoplasms Mice Mice, Inbred BALB C Mice, Nude Microscopy, Electron Microscopy, Electron, Scanning N-Acetylneuraminic Acid RNA, Messenger Research Support, Non-U.S. Gov't Tumor Cells, Cultured Umbilical Veins

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

围手术期支气管哮喘的处理

中国实用内科杂志 2009年第4期29卷 297-299页

作者：李芹子孔灵菲中国医科大学附属第一医院呼吸疾病研究所沈阳110001

支气管哮喘是一种对多种刺激发生反应的慢性呼吸道炎症性疾病。目前,全世界有约2亿支气管哮喘患者,而且发病率在逐年上升,所以,支气管哮喘患者恰当的围手术期的治疗显得尤为重要。支气管哮喘患者围手术期肺部并发症的发病风险高,这些并... 详细信息

支气管哮喘是一种对多种刺激发生反应的慢性呼吸道炎症性疾病。目前,全世界有约2亿支气管哮喘患者,而且发病率在逐年上升,所以,支气管哮喘患者恰当的围手术期的治疗显得尤为重要。支气管哮喘患者围手术期肺部并发症的发病风险高,这些并发症导致严重的病死率。因此,在围手术期控制好支气管哮喘、防治肺部并发症对提高手术成功率十分重要。

关键词：哮喘围手术期

Relevance between major depression disorder and respiratory diseases

在线全文

学校读者我要写书评

暂无评论

Relevance between major depression disorder and respiratory ...

Impact of virus genotype on interferon treatment of patients with chronic hepatitis C: a multicenter controlled study

中国药理学会药学监护专业委员会第一届第四次学术研讨会

作者： Huai-Liang Wang (china medical university,shenyang 110001,china)

Objective:there is a link between anxiety and respiratory symptoms,probably mediated by the serotonergic *** has been found that a high proportion of patients with panic disorder suffer from COPD and the prevalence of panic disorder has been shown to be higher in patients with *** selecetive serotonin reuptake inhibitors (SSRIs),such as fluoxetine,sertraline,paroxetine et al,are effective

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2004年第3期3卷 369-374页

作者： Yao Xie, Dao-Zhen Xu, Zhi-Meng Lu, Kang-Xian Luo, Ji-Dong Jia, Yu-Ming Wang,Gui-Zhen Zhao, Shu-Lin Zhang and Da-Zhi Zhang Department of Infeetious Diseases , Beijing Ditan Hos-pital, Beijing 100011 , china Department of Infec-tious Diseases, Ruijin hospital, Shanghai 200025, china De-partment of Infectious Diseases, Naifang hospital, first Military medical U-niversity, Guangzhou 510515, china (Luo KX) Center of Liver Disease,Beijing Friendship hospital, Beijing 100050, china (Jia J D ) Institute ofInfectious Disease, Southwest hospital, Third Military medical university,Chongqing 410032, china Department of Infectious Disea-ses, Second hospital, china medical university, shenyang 110004, china Department of Infectious Diseases, first hospital, Xi’ an Jiao-tong university, Xi’ an 710061 , china ) Liver Disease Centerof Chongqing, Second hospital, Chongqing medical university,Chongqing 410010, china Department of Infectious Diseases Beijing Ditan Hospital Beijing 100011 China. xieyao@***

BACKGROUND: Some factors have been reported to besassociated with a greater likelihood of sustained viral re-sponse ( SVR) in the interferon (IFN) treatment of chronichepatitis C. The factors include HCV genotype, HCVRNA level in serum, state of liver disease, baseline bodyweight, age, sex, and race. The aim of this trial was to in-vestigate the influence of HCV genotype on the IFN treat-ment of patients with chronic hepatitis ***: The genotypes of HCV virus were determinedin the patients with chronic hepatitis C from several hospi-tals of china enrolled into the randomized, opened andcontrolled trial of Peg-IFN alpha-2a (pegasys) treatment,controlled with IFN-α-2a (roferon-A). The serum ALTlevels and HCV RNA concentrations of the patients weredetected before and at the end of treatment and during thefollow-up. The influence of HCV genotype on the IFNtreatment of patients with chronic hepatitis C was analyzedin intention-to-treat (ITT) ***: The HCV genotypes of 202 patients were deter-mined. Of these patients, 158(78.22%) were infected withgenotype 1 HCV and 44(21.78%) with genotype *** viral response at the end of treatment (ETVR) andsustained viral response (SVR) rates were 53.80% and25.32% respectively in patients with genotype 1 HCV, butthey were 61.36% and 43.18% in patients with genotypenon-1. The difference of SVR between patients with geno-type 1 HCV and those with genotype non-1 was significant(P =0.021). After being grouped by the used drugs, theETVR rates of patients infected with genotype 1 and non-1HCV were 76.83% and 80.95% in the patients treated withpegasys (P =0.686); but their SVR rates were 35.37% and66.67% (P =0. 01). The viral relapse rate of genotype 1HCV (55.56%) was significantly higher than that of geno-type non-1 HCV (23.53%) (P=0.02). In roferon-A group,the ETVR and SVR rates of patients with genotype 1 HCVwere 28.95% and 14.47% respectively, which were lowerbut not more significant than those of patients with ge

关键词： hepatitis C virus genotype chronic hepatitis C interferon PEG-IFN