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Body weight and range usage affect net energy utilisation in commercial free-range laying hens when evaluated in net energy chambers

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Animal Nutrition 2020年第2期6卷 192-197页

作者： Manisha Kolakshyapati Shu-Biao Wu Terence Z.Sibanda Santiago Ramirez-Cuevas isabelle Ruhnke The School of Environmental and Rural Science Faculty of ScienceAgricultureBusiness and LawUniversity of New EnglandArmidale2351NSWAustralia FCR Consulting Group Brisbane4000QLDAustralia

Within a given free-range flock,some hens prefer to spend the majority of their time in the shed(stayers),while others frequently access the range(rangers).Laying performance has been associated not only with the development of these sub-populations but also with different body weights(BW).The purpose of this study was to determine if range usage,BW or a combination of both is associated with energy metabolism and as such co ntribute to improved hen ***-eight Lohmann Brown hens at 74 wk of age were selected from a commercial free-range farm based on their BW and range usage over a 56-week *** a 2 × 2 factorial arrangement,hens were either classified as heavy(mean ± SEM;2.01±0.02 kg,n=24) or light(1.68±0,01 kg,n=24),and also classified as rangers(accessed the range for 84.1 % of available days,242±3.75 d;n=24) or stayers(accessed the range for 7.17% of available days;23,4±6.08 d,n=24).Stayers had significantly higher metabolizable energy(ME) intake per metabolic BW per d(0.852 vs.0.798 MJ/kg BW0.75 perd;P=0.025),higher heat production(0.637 vs.0.607 MJ/kg BW0.75 perd;P=0.005),higher heat increment(0.267 vs.0.237 MJ/kg BW0.75 per d;P=0.005) and retained more nitrogen(1.59 vs.1.46 g/hen perd;P=0.023) compared to the *** hens had significantly higher metabolic energy intake per metabolic BW(0.854 vs.0.796 MJ/kg BW0.75 per d;P=0.018),net energy(NE) intake(0.595 vs.0.551 MJ/kg BW0.75 per d;P=0.032),and retained energy(0.225 vs.0.181 MJ/kg BW0.75 per d;P=0.032),as well as lower heat production(0.936 vs.1.003 MJ/hen per d;P=0.002) compared to heavier *** interaction was observed across levels of analysis *** light stayers and light *** light rangers had significantly higher NE intake compared to the light stayers(9.77 vs.9.27 MJ/kg BW0.75 per d;P=0.024).In conclusion,light hens were more energy efficient compared to heavy ***,light rangers had a more efficient feed utilisation compared to the light stayers.

关键词： Egg production Health Husbandry Metabolizable energy Poultry nutrition Welfare

Synthesis and Photophysical Properties of Novel Rod-shaped and Star Shaped Fluorescent Phosphane Derivatives

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复旦学报（自然科学版） 2007年第5期46卷 590-,592页

作者： isabelle Leray Minh-Huong Ha-Thi Véronique Michelet Laboratoire PPSM ENS-Cachan61 Avenue du Président Wilson94235 CachanFrance Laboratoire de Synthèse Sélective Organique et Produits Naturels ENSCPUMR 757311 rue Pierre et Marie Curie 75231 Paris Cedex 05France

1 Results Over the past few years significant research has been directed toward the development of organic materials for potential application in molecular photonic devices[1] and the development of sensors[2].Interest in these materials is primarily due to the infinite numbers of possible molecular structures with the desired properties,by virtue of the tremendous capabilities of organic *** the development of a new fluorescent molecular sensor consisting of a recognition moiety linked to a f...

关键词： synthesis photophysical procperties fluorescent phosphane derivatives

Intraoperative hemodynamic parameters of middle cerebral artery and other artery aneurysms utilizing transcranial Doppler ultrasonography

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Neural Regeneration Research 2010年第11期5卷 874-880页

作者： Jianjun Sun Shuo Wang Yuanli Zhao Dong Zhang Yoko Kato O isabelle Liu O Jizong Zhao Department of Neurosurgery Third Hospital Peking University Beijing 100191 China Department of Neurosurgery Tiantan Hospital Affiliated to Capital Medical University Beijing 100050 China Department of Neurosurgery Fujita Health University Toyoake Aichil 470-1192 Japan Washington University in St Louis School of Medicine St Louis MO 63110 USA

BACKGROUND： Hemodynamic changes accompany the initiation, development and rupture of middle cerebral artery （MCA） aneurysms. The complexity of the intraaneurysmal hemodynamic factors has not been completely clarified by the indirect measures and methods used in previous studies. OBJECTIVE： To evaluate correlations of intraoperative hemodynamic factors to initiation and rupture of MCA aneurysms. DESIGN, TIME AND SETTING： A case-control study was performed at the Department of Neurosurgery, Tiantan Hospital Affiliated to Capital Medical University, China between March and October 2008. PARTICIPANTS： A total of 12 consecutive patients diagnosed with MCA aneurysms （MCA aneurysms group） and five patients without middle cerebral artery aneurysms （with aneurysms located at other arteries, control group） were enrolled at the Department of Neurosurgery, Tiantan Hospital Affiliated to Capital Medical University, China. METHODS： The proximal and distal arteries of MCA aneurysms were exposed visibly in the MCA aneurysm group. The M1 segment of MCA without the aneurysm and the aneurysm on other arteries were also exposed visibly in the control group. Hemodynamic indices were then measured using an intraoperative 16 MHz probe installed in a Multi-Dop TCD8X4 device. MAIN OUTCOME MEASURES： Mean （time-averaged velocity） difference, maximum mean, pulsatility index difference, maximum pulsatility index, resistance index difference, maximum resistance index; correlation of development and rupture of MCA aneurysms to intraoperative hemodynamic factors of the parent artery. RESULTS： A total of 12 patients underwent microsurgery for treatment to occlude 15 MCA aneurysms. Of the 15 MCA aneurysms, 12 were located at the bifurcation, two at the M1 segment and one at the M3 segment; eight of the aneurysms were unruptured and seven were ruptured. The whole indices with combination mean difference, maximum mean, and maximum pulsatility index of the aneurysms were important factors influencing t

关键词： aneurysms middle cerebral artery intraoperative hemodynamics impingement force rupture brain injury neural regeneration

Protein Phosphatase 2C of Toxoplasma Gondii Interacts with Human SSRP1 and Negatively Regulates Cell Apoptosis

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Biomedical and Environmental Sciences 2014年第11期27卷 883-893页

作者： GAO Xue Juan FENG Jun Xia ZHU Sen LIU Xiao Hui TARDIEUX isabelle LIU Lang Xia Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes Institute of Life and Health EngineeringJinan University Institut Cochin Université DescartesTeam FRM ‘Barriers and Pathogens’22 Rue Méchain

Objective The protozoan Toxoplasma gondii expresses large amounts of a 37 kDa Type 2C serine-threonine phosphatase,the so-called TgPP2 C which has been suggested to contribute to parasite growth *** expression in mammalian cells also indicated that the enzyme could regulate growth and *** this study,we aimed to investigate the interaction of TgPP2 C with human SSRP1（structure-specific recognition protein 1） and the effects of TgPP2 C on cell *** The yeast two hybrid system,His-tag pull-down and co-immunoprecipitation assays were used to confirm the interaction of TgPP2 C with SSRP1 and determine the binding domain on *** evaluation of cell apoptosis was performed using cleaved caspase-3 antibody and Annexin-V/PI kit combined with flow *** We identified human SSRP1 as an interacting partner of TgPP2 *** C-terminal region of SSRP1 including the amino acids 471 to 538 was specifically mapped as the region responsible for interaction with TgPP2 *** overexpression of TgPP2 C down-regulated cell apoptosis and negatively regulated apoptosis induced by DRB,casein kinase II（CKII） inhibitor,through enhanced interaction with *** TgPP2 C may be a parasitic factor capable of promoting cell survival through interaction with the host protein SSRP1,thereby creating a favorable environment for parasite growth.

关键词： Apoptosis SSRP1 TgPP2C Toxoplasma gondii

龙山文化白陶产地的初步研究——以两城镇等遗址白陶样品为例

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考古 2024年第2期 89-106,F0002页

作者：郭明建文德安栾丰实朱铁权伊莎贝尔·德鲁克万嘉丽陆青玉孙波梁中合暨南大学历史学系广州市510632 耶鲁大学人类学系美国纽黑文市06520 山东大学历史文化学院济南市250100 中山大学社会学与人类学学院广州市510275 威斯康星大学麦迪逊分校人类学系美国麦迪逊市53706 义乌市博物馆浙江省金华市322000 山东省文物考古研究院济南市250012 中国社会科学院考古研究所北京市100101

利用岩相及主量和微量化学元素分析,对城子崖、丁公与两城镇、尧王城等两组龙山文化遗址发现的白陶样品进行检测和对比,证明这些白陶样品原料大多为本地获得。但城子崖遗址相对较容易获取优质陶土,两城镇遗址的白陶来源则呈现出多元化,... 详细信息

利用岩相及主量和微量化学元素分析,对城子崖、丁公与两城镇、尧王城等两组龙山文化遗址发现的白陶样品进行检测和对比,证明这些白陶样品原料大多为本地获得。但城子崖遗址相对较容易获取优质陶土,两城镇遗址的白陶来源则呈现出多元化,部分优质白陶器应来自西部的城子崖、丁公等遗址。

关键词：龙山文化白陶产地岩相分析化学元素地质背景

Colon cancer stemness as a reversible epigenetic state:Implications for anticancer therapies

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World Journal of Stem Cells 2019年第11期11卷 920-936页

作者： Audrey Vincent Aicha Ouelkdite-Oumouchal Mouloud Souidi Julie Leclerc Bernadette Neve isabelle Van Seuningen Lille University Institut National de la Sante et de la Recherche MédicaleCHU LilleUMR-S 1172-Jean-Pierre Aubert Research CenterLille F-59000France Department of Biochemistry and Molecular Biology Lille University HospitalLille F-59000France

The recent discovery of cancer cell plasticity,*** ability to reprogram into cancer stem cells(CSCs)either naturally or under chemotherapy and/or radiotherapy,has changed,once again,the way we consider cancer *** cancer stemness is a reversible epigenetic state rather than a genetic identity,opportunities will arise for therapeutic strategies that remodel epigenetic landscapes of ***,the systematic use of DNA methyltransferase and histone deacetylase inhibitors,alone or in combination,in advanced solid tumors including colorectal cancers,regardless of their molecular subtypes,does not seem to be the best *** this review,we first summarize the knowledge researchers have gathered on the epigenetic signatures of CSCs with the difficulty of isolating rare populations of *** raise questions about the relevant use of currently available epigenetic inhibitors(epidrugs)while the expression of numerous cancer stem cell markers are often repressed by epigenetic *** markers include the three cluster of differentiation CD133,CD44 and CD166 that have been extensively used for the isolation of colon ***,we describe current treatment strategies using epidrugs,and we hypothesize that,using correlation tools comparing associations of relevant CSC markers with chromatin modifier expression,we could identify better candidates for epienzyme targeting.

关键词： Cancer stem cells Colon cancer Epigenetics Chromatin modifying enzymes CD44 CD133 CD166

French Concerns Over the Chinese Presence in Francophone Africa

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French Concerns Over the Chinese Presence in Francophone Afr...

作者： SUPLISSON Eugénie isabelle Marie Agnès 上海交通大学

学位级别：硕士

In this thesis,I have studied how the growing Chinese presence in the traditional French sphere of influence that is Francophone Africa,has impacted the way Paris conducts its Foreign *** since its defeat in 1870,France has sought to regain its grandeur and global rank which has been exacerbated by the Second World ***,it has always relied heavily on its colonies to maintain its rank on the world *** decades,France managed to retain its influence in Francophone Africa and Franco-African relations did not change much despite the major changes that have affected the world order such as decolonization and the end of the cold *** is,however,after the Chinese presence grew stronger on the continent that the French African Policy towards Francophone Africa changed more *** is why,in order to pursue its foreign policy goals of maintaining a global rank and（residual）great power role,France had to adjust its African ***’s survival in its former sphere of influence could only be realized by Europeanizing a part of its African policy and thus benefit from the European multiplier ***,by promoting human and sustainable investments with a focus on young entrepreneurs,France is trying to differentiate itself from all the other *** implementing these new strategies,the French Nation can continue to rely on Africa to pursue its great power aspirations and in the process contain the Chinese presence in Francophone Africa.

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Asymptotic Expansion of Temperature Close to a Singularity of a Plate

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World Journal of Mechanics 2011年第3期1卷 109-114页

作者： isabelle Titeux 不详

The thermal conduction in a thin laminated plate is considered here. The lateral surface of the plate is not regular. Consequently, the boundary of the middle plane admits a geometrical singularity. Close to the origin, the lateral edge forms an angle. We shall prove that the classical bidimensional problem associated with the thin plate problem is not valid. In this paper, using the boundary layer theory, we describe the local behavior of the plate, close to the perturbation.

关键词： Thin Plate Boundary Layers Singularities Asymptotic Expansion

γ辐射和高温对放射性废物水泥固化体强度的影响(英文)

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硅酸盐学报 2012年第1期40卷 33-38页

作者： Bart CRAEYE Geert De SCHUTTER isabelle GERARDY Artesis University College of Antwerp Department of Applied Engineering ＆ Technology Antwerp Belgium Magnel Laboratory for Concrete Research Department of Structural Engineering Ghent University Ghent Belgium ISIB Engineering Education Institute Physical and Nuclear Department Brussels Belgium

为了处理高活性、放热性C级放射性废弃物,在比利时通常采用圆柱体混凝土"超级容器"作为基本途径。"超级容器"是合成的废弃物包,废弃物由碳钢包裹组成,碳钢被波特兰水泥制成的"缓冲器"包裹。自密实混凝土作为一种特殊类型的混凝土,正被... 详细信息

为了处理高活性、放热性C级放射性废弃物,在比利时通常采用圆柱体混凝土"超级容器"作为基本途径。"超级容器"是合成的废弃物包,废弃物由碳钢包裹组成,碳钢被波特兰水泥制成的"缓冲器"包裹。自密实混凝土作为一种特殊类型的混凝土,正被考虑用来制备"缓冲器"。一旦"缓冲器"被浇筑并且硬化程度很高时,放射性废弃物就被包裹在"缓冲器"内,存在的缝隙可以采用新拌灌浆料填充(例如自密实砂浆)。用盖子将"超级容器"密封后应用于"超级容器"的混凝土层,即混凝土缓冲器、灌浆料及盖子在硬化期间(灌浆料)与硬化之后("缓冲器"与盖子)将暴露在废弃物热场与辐射场内。因此,需要解决2个主要的问题:1)γ射线(α与β射线被碳钢包裹层阻断,中子的影响可以忽略)对灌浆料硬化强度的影响;2)温度升高(从20℃升高到105℃)对硬化试件强度的影响。为了证实强度是否损失并确定强度损失后的主要机理,采用荧光显微镜,在砂浆或混凝土薄片的截面上直接分析毛细孔隙率。

关键词： γ放射热荷载强度毛细孔隙率