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Changes in demand and supply of ecosystem services under scenarios of future land use in Vorarlberg, Austria

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Journal of Mountain Science 2019年第12期16卷 2793-2809页

作者： SAUTER isabel KIENAST Felix BOLLIGER Janine WINTER Benjamin PAZuR Robert Swiss Federal Research Institute WSL Zurcherstrasse 1118903 BirmensdorfSwitzerland ALPS-Centre for Climate Change Adaptation Grabenweg 686020 InnsbruckAustria Institute of Geography University of InnsbruckInnrain 526020 InnsbruckAustria Institute of Geography Slovak Academy of SciencesStefanikova 4981473 BratislavaSlovakia

Ecosystem services(ES)are highly impacted by human-induced land-use *** urbanization and agricultural land abandonment in Western Europe necessitate assessments of future land-change impacts on ES to ensure sustainable service *** present study aims at evaluating future demand and supply of three key services(flood protection,nearby recreation and biodiversity)in the mountainous region of Vorarlberg,*** mapped the ES for the referenced time step 2016 and two scenarios for 2050,assuming the continuation of current land-change trends and pressure on landscape *** for the referenced landscape in 2016 show the highest ES supply for intermediate levels,while ES supply was low in the lowlands and valley bottoms and in high-elevation *** found a high positive correlation of ES with the distribution of forested *** contrast,service demand was highest in lowelevation areas and decreased with increasing *** indicates that densely settled and intensively used agricultural areas currently suffer from ES *** projected future development of land use showed an increase in both supply and demand of the selected *** overall service supply increased more than the respective demand due to some reforestation of open *** forests were found to be important synergistic areas for overall service provision,we expect decreasing demand on related ***,demand was found to exceed the supply of ES,especially in the densely populated Rhine valley-requiring further policy *** ES-related information may contribute to regional policy making and ensure the long-term provision of ESs for future generations.

关键词： Land-use change Future land-use scenarios Regional assessment Ecosystem services Synergies Conflicts

A qualitative study on the pulsatile flow phenomenon in a dense fly ash pneumatic conveyor

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Particuology 2014年第6期12卷 81-91页

作者： Wei Chen Kenneth C.Williams isabel Jabs Mark G.Jones Centre for Bulk Solids and Particulate Technologies Newcastle Institute for Energy and ResourcesThe University of Newcastle Faculty of Mechanical Engineering Leibniz University of Hanover

Understanding of the dynamic particulate flow structures within a dense gas-fly ash pneumatic conveyor must be improved in order to better aid its design *** complex pulsatile movement of the gas-fly ash mixture dominates the flow performance within the pipeline,and historically,non-invasive measurement devices such as the electrical capacitance tomography（ECT） were often used to sufficiently capture the flow ***,inadequate studies have been conducted on the pulsatile flow phenomenon,which directly relate to the gas-fly ash two-phase flow *** paper aims to investigate the pulsatile flows using an ECT ***,pulsatile flow patterns under various experimental conditions were obtained through *** within a flow were then characterised into pulse growth and decay segments,which represent the superficial fluidisation and deaeration processes during ***,structural and statistical analyses were performed on the pulse growth and decay *** suggested that the increasing air mass flow rate led to the decrease of the superficial fluidisation/deaeration magnitude,however,the increase of the superficial fluidisation/deaeration ***,the air mass flow rate was indicated as the dominant factor in determining the pulsing statistical *** research provides fundamental insights for further modelling the dense fly ash pneumatic flows.

关键词： Pneumatic conveying Electrical capacitance tomography Fly ash Pulsatile flows Flow pattern analysis

Origin and evolution of the genera Lonsdaleia and Actinocyathus:Insights for the Mississippian palaeogeography from the western Palaeotethys

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Journal of Palaeogeography 2023年第2期12卷 296-310页

作者： isabel Rodríguez-Castro Ian D.Somerville Sergio Rodríguez Departamento de Geodinamica Estratigrafía y PaleontologíaUniversidad Complutense de Madrid28040MadridSpain UCD School of Earth Sciences University College DublinBelfieldDublin 4Ireland Instituto de Geociencias(CSIC UCM)Ciudad Universitaria28040MadridSpain

Representatives of the subfamily Lonsdaleiinae Chapman,1893 are common in the Mississippian of the western Palaeotethys.A general analysis of the origin,distribution and evolution of that subfamily has been *** most probable hypothesis for the origin of the genus Lonsdaleia McCoy,1849 is to acquire colonialism via the genus Axophyllum Milne Edwards and Haime,*** d'Orbigny,1849 would be a descendant of Lonsdaleia by increasing integration in the *** first occurrences of Lonsdaleia have been recorded in the lower Visean from northern Britain and northern Tianshan Mountains of northwestern China,but the diversification and migration to the whole Palaeotethys only happened in the late *** hypotheses are proposed on that *** Serpukhovian was also a period of migrations and diversification for these *** Lonsdaleia and Actinocyathus have been recorded in Bashkirian refuges,the Sverdrup Basin in northern Laurasia and the Tindouf Basin in northern Africa,*** division of the western Palaeotethys into six subprovinces based on the distribution of corals is proposed.

关键词： Carboniferous Palaeotethys Biogeography Evolution Rugosa

Evolution of radical hysterectomy for cervical cancer along the last two decades: single institution experience

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Chinese Journal of Cancer Research 2016年第2期28卷 215-220页

作者： Claudia Arispe Ana isabel Pomares Javier De Santiago Ignacio Zapardiel Gynecologic Oncology Department La Paz University Hospital

Background： The radical hysterectomy （RH） surgical technique has improved along the years. It is used for the treatment of cervical cancer, endometrial cancer when affecting the cervix, and upper vaginal carcinomas. Our aim was to describe the historical evolution of the technique after the introduction of laparoseopy at our institution. Methods： We performed a retrospective review of medical records of patients who underwent RH, grouped in three periods according to the year of surgery： 1990-1999, 2000-2009 and 2010-2013. Patients＇ characteristics, pathologic details, intraoperative and postoperative complications were analyzed and comoared throughout the time periods. Results： A total of 102 cases of RH were performed at our center during the study period. Among all data collected, the presence of necrosis, age, number of lymph nodes, surgery route, operating time, hospital stay, blood loss and transfusion requirement were statistically significant different among groups. Conversion to laparotomy rate was 19% for the second period compared to the absence of cases in the last one. No significant differences （P=0.124） were observed in the adjuvant treatment received among the three different groups. At the time of the last contact the patients free of disease were 12 （85.7%）, 53 （91.3%） and 26 （86.6%） respectively （P=0.406）. Regarding the disease-free interval, we found significant better outcomes in the group of laparotomy compared to laparoscopy （P=0.015）.Conclusions： Laparoscopic RH is an acceptable surgery with advantages like magnified vision of the operation＇s field, lower surgical complications, shorter hospital stay and earlier resumption to daily activities.

关键词： Gynaecological cancer radical hysterectomy (RH) laparoscopy cervical cancer

Analysis of hepatitis C virus-positive organs in liver transplantation

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World Journal of Hepatology 2022年第9期14卷 1840-1843页

作者： isabel Legaz Manuel Muro Department of Legal and Forensic Medicine Biomedical Research InstituteRegional Campus of International Excellence"Campus Mare Nostrum"Faculty of MedicineUniversity of MurciaMurcia 30100Spain Department of Immunology Service Instituto Murciano de Investigación BiosanitariaHospital Clínico Universitario Virgen de la ArrixacaMurcia 30120Spain

The authors of this study note that in liver transplantation(LT),the survival rates of hepatitis C virus(HCV)-positive donors and HCV-negative receivers are compa-rable to those of HCV-negative donors and ***-acting antiviral(DAA)therapies have nearly 100%effectiveness in treating *** 2006 and 2016,the percentages of HCV-positive patients on the waiting list and HCVpositive LT recipients fell by 8.2 percent and 7.6 percent,*** from April 1,2014,in which the donor and receiver were both at least 18 years old and had a positive HCV status,were the only ones eligible for the *** analysis for this study was restricted to the first transplant recorded for each patient using a data element that documented the number of prior transplants for each recipient,although some recipients appeared multiple times in the data ***-positive recipients or people with fulminant hepatic failure were the main beneficiaries of primary biliary cirrhosis among HCV-positive ***,there is still a reticence to use HCV-positive donor organs in HCV recipients due to clinical and ethical *** survival rates between HCV-positive donors and recipients and HCV-negative donors and receivers illustrate the efficacy of these DAA regimens.

关键词： Hepatitis C virus Liver transplant Graft survival United network for organ sharing Direct-acting antiviral

Importance of BRCA mutation for the current treatment of pancreatic cancer beyond maintenance

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World Journal of Gastroenterology 2021年第39期27卷 6515-6521页

作者： Joaquina Martínez-Galán isabel Rodriguez Octavio Caba Department of Medical Oncology Virgen de las Nieves University HospitalGranada 18014Spain Institute of Biopathology and Regenerative Medicine(IBIMER) University of GranadaGranada 18016Spain

In this editorial,we comment on pancreatic cancer(PC),one of the most aggressive and lethal *** minimal improvements in survival rates have been achieved over recent *** chemotherapeutic regimens have little impact,and surgical resection remains the only reliable curative *** address current treatment options for these patients,focusing on the usefulness of breast cancer(BRCA)gene mutation as a prognostic biomarker and predictor of response to *** survival outcomes have been reported in patients with PC and mutant BRCA gene treated with first-line platinum-based ***,it appears appropriate to include BRCA gene status among clinical criteria used to select the chemotherapy *** addition,maintenance treatment with poly(ADP-ribose)polymerase inhibitors has been found to improve progression-free survival in patients with PC and mutated BRCA whose disease does not progress after first-line platinum-based *** combination has therefore been proposed as the optimal treatment regimen for these patients.

关键词： Pancreatic cancer Treatment BRCA Mutation Poly(ADP-ribose)polymerase inhibitor Maintenance

Relation of COVID-19 with liver diseases and their impact on healthcare systems:The Portuguese case

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World Journal of Gastroenterology 2023年第6期29卷 1109-1122页

作者： Sara Fernandes Milaydis Sosa-Napolskij Graça Lobo isabel Silva Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto(ICBAS-UP) Porto 4050-313Portugal CINTESIS@RISE Center for Health Technology and Services Research at The Associate Laboratory RISE–Health Research NetworkFaculty of Medicine of The University of PortoPorto 4200-219Portugal Laboratory of Pharmacology and Neurobiology–Department of Immuno-physiology and Pharmacology Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto(ICBAS-UP)Porto 4050-313Portugal Center for Drug Discovery and Innovative Medicines(MedInUP) Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto(ICBAS-UP)Porto 4050-313Portugal

BACKGROUND The impact caused by the coronavirus disease 2019(COVID-19)on the Portuguese population has been addressed in areas such as clinical manifestations,frequent comorbidities,and alterations in consumption ***,comorbidities like liver conditions and changes concerning the Portuguese population's access to healthcare-related services have received less *** To(1)Review the impact of COVID-19 on the healthcare system;(2)examine the relationship between liver diseases and COVID-19 in infected individuals;and(3)investigate the situation in the Portuguese population concerning these *** For our purposes,we conducted a literature review using specific *** COVID-19 is frequently associated with liver ***,liver injury in COVID-19 individuals is a multifactor-mediated ***,it remains unclear whether changes in liver laboratory tests are associated with a worse prognosis in Portuguese individuals with *** COVID-19 has impacted healthcare systems in Portugal and other countries;the combination of COVID-19 with liver injury is *** liver damage may represent a risk factor that worsens the prognosis in individuals with COVID-19.

关键词： COVID-19 Healthcare systems Liver Portuguese individuals Comorbidities Clinical outcomes

Helicobacter pylori infection- recent developments in diagnosis

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World Journal of Gastroenterology 2014年第28期20卷 9299-9313页

作者： Ana isabel Lopes Filipa F Vale Mónica Oleastro Centro Académico de Medicina de Lisboa Faculdade de Medicina da Universidade de Lisboa Centro de Patogénese Molecular Unidade dos Retrovírus e Infec??es AssociadasInstituto de Medicina Molecular e Instituto de Investiga??o do MedicamentoFaculdade de FarmáciaUniversidade de Lisboa Laboratório Nacional de Referência das Infe??es Gastrintestinais Departamento de Doen?as InfeciosasInstituto Nacional de Saúde Dr Ricardo Jorge

Considering the recommended indications for Helicobacter pylori(***)eradication therapy and the broad spectrum of available diagnostic methods,a reliable diagnosis is mandatory both before and after eradication *** highly accurate tests should be used in clinical practice,and the sensitivity and specificity of an adequate test should exceed 90%.The choice of tests should take into account clinical circumstances,the likelihood ratio of positive and negative tests,the cost-effectiveness of the testing strategy and the availability of the *** review concerns some of the most recent developments in diagnostic methods of *** infection,namely the contribution of novel endoscopic evaluation methodologies for the diagnosis of *** infection,such as magnifying endoscopy techniques and *** addition,the diagnostic contribution of histology and the urea breath test was explored recently in specific clinical settings and patient *** studies recommend enhancing the number of biopsy fragments for the rapid urease *** culture from the gastric biopsy is the gold standard technique,and is recommended for antibiotic susceptibility *** is used for initial screening and the stool antigen test is particularly used when the urea breath test is not available,while molecular methods have gained attention mostly for detecting antibiotic resistance.

关键词： Helicobacter pylori Diagnosis Endoscopy Histology Culture Urea breath test Stool antigen test Serology Molecular methods

Host preference of the bean weevil Zabrotes subfasciatus

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Insect Science 2008年第4期15卷 335-341页

作者： isabel Ribeiro do Valle Teixeira Angel Roberto Barchuk Fernando Sergio Zucoloto Department of Biology Centro Universitario da Fundacao Educacional de Guaxupe Minas Gerais Department of Biology Faculdade de Filosofia Ciencias e Letras de Ribeirao Preto Universidade de Sao Paulo Sao Paulo Department of Biological Sciences Universidade Federal de Alfenas UnifaI-MG Alfenas Minas Gerais Brazil

It is largely known that the range of an insect diet is mostly determined by oviposition behavior, mainly in species with endophytic larvae such as Zabrotes subfasciatus. However, the proximate factors determining host choice and the subsequent steps leading to the expansion or reduction of the host number and occasional host shifts are largely unknown. We analyzed various factors determining host preference of Z. subfasciatus through the evaluation of：（i） oviposition preference of a wild population of Z. subfasciatus on the usual host （bean） and unusual hosts （lentil, chickpea and soy）, and the performance of the offspring; （ii） artificial selection for increasing preference for hosts initially less frequently chosen; （iii） comparison of oviposition behavior between two different populations （reared for -30 generations in beans or chickpeas, respectively）; （iv） oviposition timing on usual and unusual hosts; and （v） identification of preference hierarchies. We found that when using unusual hosts, there is no correlation between performance and preference and that the preference hierarchy changes only slightly when the population passes through several generations on the less frequently accepted host. We also found a positive response to artificial selection for increasing oviposition on the less preferred host; however, when the host-choice experiment involved two varieties of the usual host, the response was faster than when the choice involved usual and unusual hosts. Finally, beetles reared on an unusual host （chickpea） for 26 generations showed similar good fitness on both usual and unusual hosts, indicating that the use of a new host does not necessarily result in the loss of performance on the original host. Nevertheless, this population showed lower fitness on the usual host than that of the original population, suggesting an underlying partial trade-off phenomenon which may contribute to a broadening of diet of this insect species.

关键词： artificial selection evolution Phaseolus Cicer plant-insect interaction