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Prevalence and Distribution of Tick-Borne Hemoparasites in cattle from the Noun and Ndé Divisions of the West Region, cameroon

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Open Journal of Veterinary Medicine 2024年第8期14卷 193-202页

作者： Rostand cedric Pami Mbitkebeyo kingsley Tanyi Manchang corinne Raïssa Ngnameko Geraud c. Tasse Multipurpose Research Station Institute of Agricultural Research Station Bangangte Cameroon Laboratory of Parasitology and Ecology Department of Animal Biology and Physiology Faculty of Science The University of Yaounde 1 Yaounde Cameroon Department of Veterinary Medicine Faculty of Agriculture and Veterinary Medicine University of Buea Buea Cameroon Pharmacology and Drug Discovery Laboratory Institute of Medical Research and Medicinal Plants Studies Yaound Cameroon Department of Pharmacology University of the Free State Bloemfontein South Africa

Background and Objective: Tick-borne hemoparasitic illnesses pose a serious threat to the well-being and productivity of cattle. This study aimed to investigate the prevalence of tick-borne hemoparasites in cameroon, with a specific focus on the Noun and Nde Divisions of the West Region. Methodology: A total of 423 cattle from 10 villages in both divisions were included in the study. Blood smears were prepared and subjected to microscopic screening for Babesia and Anaplasma parasites. Results: The prevalence of Anaplasma was found to be 23.4%, while Babesia exhibited a seroprevalence of 17.3%. Samples from Institute of Agricultural Research for Development (IRAD) and Koupa Ngangnou demonstrated significantly higher prevalence rates, potentially influenced by climate variations affecting tick populations. Additionally, 17.3% of the animals exhibited low hematocrit levels, indicative of anemia. No significant associations were observed between the presence of hemoparasite infection and cattle characteristics. conclusion: This study provides fundamental data on the extensive distribution and impact of tick-borne hemoparasites in a significant cattle-producing region of cameroon.

关键词： Tick-Borne Hemoparasites cattle Prevalence cameroon

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Optimization of process conditions for drying of catfish(clarias gariepinus)using Response Surface Methodology(RSM)

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Food Science and Human Wellness 2019年第1期8卷 46-52页

作者： Elijah George Ikrang kingsley charles Umani Department of Agricultural and Food Engineering Faculty of EngineeringUniversity of UyoUyoAkwa Ibom StateNigeria Department of Agricultural Engineering Faculty of EngineeringAkwa Ibom State UniversityMkpat EninAkwa Ibom StateNigeria

Drying is applied to lower the moisture content of fish to a level that can prevent the growth of mould and infestation of micro-organism and thus minimizes microbial *** goal of this work was to optimize the process conditions during electrical oven drying of *** content(Mc)was quantitatively investigated during the drying process of catfish sizes using response surface methodology(RSM)to obtain minimum moisture *** independent process variables for the drying process were temperature(50–70◦c),product thickness(10–20 mm),salt concentration(0–20%)and drying time(480–600 min.).Two factorial interaction(2FI)regression model describing the effects of independent drying process variables on the moisture content was *** effects of temperature and drying time were more pronounced for Mc than the thickness and salt *** optimum conditions were found to be temperature=63.43◦c,product thickness=14.81 mm,salt concentration=9.07%and drying time=600 *** these optimum conditions,moisture content was found to be 2.64%*** of experimental results with the empirical model was evaluated using coefficient of correlation(R2)which was found for the model equation as,R2=0.994.

关键词： Optimization Oven drying Drying parameters catfish Response surface methodology

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Risk factors of treatment default and death among tuberculosis patients in a resource-limited setting

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Asian Pacific Journal of Tropical Medicine 2014年第12期7卷 977-984页

作者： isa.c Alobu Sarah N.Oshi Daniel c.Oshi kingsley N.Ukwaja National Tuberculosis and Leprosy control Programme Ministry of HealthAbakalikiEbonyi StateNigeria centre for Development and Reproductive Health Enugu.Enugu StateNigeria Department of Internal Medicine Federal Teaching HospitalAbakalikiEbonyi StateNigeria

Objective:To evaluate the rates,timing and determinants of default and death among adult tuberculosis patients in ***:Routine surveillance data were used.A retrospective cohort study of adult tuberculosis patients treated during 2011 and 2012 in two large health facilities in Ebonyi *** was *** logistic regression analyses were used to tdentify independent predictors for treatment default and ***:Of 1668 treated patients,the default rate was 157(9.4%),whilst 165(9.9%) ***,35.7%(56) of the treatment defaults and 151(91.5%) of deaths occurred during the intensive phase of *** of default increased with increasing age(adjusted odds ratio(aOR) 1.2;95%confidence interval(cI)1.1-1.9).smear-negative TB case(aOR 2.3:cI 1.5-3.6).extrapulmonary TB case(aOR 2.7:cI 1.3-5.2).and patients who received the longer treatment regimen(aOR 1,6;1.1-2.2).Risk of death was highest in extrapulmonary TB(aOR 3.0:cI 1.4-6.1) and smear-negative TB cases(aOR 2.4:*** residents(aOR 1.7:cI 1.2-2.6),HIV co-infected(aOR 2.5:cI 1.7-3.6),not receiving antiretroviral therapy(aOR 1.6:cI 1.1-2.9),and not receiving cotrimoxazole prophylaxis(aOR 1.7:cI 1.2—2.6).conclusions:Targeted interventions to improve treatment adherence for patients with the highest risk of default or death are urgently *** needs to he urgently addressed by the National Tuberculosis Programme.

关键词： Tuberculosis Epidemiology Treatment default Mortality Treatment outcome Health services Nigeria

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Palynomorph assemblage biozonation of Paleogene strata in Bende–Umuahia Area,Niger Delta Basin, southeastern Nigeria

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Journal of Palaeogeography 2020年第2期9卷 168-180页

作者： Okechukwu Nicodemus Ikegwuonu Obianuju Patricia Umeji Osita Igwebuike chiaghanam kingsley KNwozor Otobong Sunday Ndukwe kingsley chukwuebuka chiadikobi Department of Geology Chukwuemeka Odumegwu Ojukwu UniversityUliNigeria Department of Geology University of NigeriaEnuguNigeria Department of Geology Federal UniversityOye-EkitiNigeria.

cenozoic sediments form extensive outcrops in the Niger Delta Basin. Detailed palynostratigraphic study was undertaken across Paleogene sequences exposed in Bende–Umuahia Area in up-dip sectors of the Niger Delta Basin, southeastern Nigeria, to establish different palynomorphs assemblage zones, with their corresponding *** analysis was carried out on 27 selected outcrop samples, using the conventional maceration technique for recovering acid-insoluble organic-walled microfossils from sediments. Three cenozoic lithostratigraphic units, including Imo Formation, Ameki Formation, and Ogwashi Formation, are exposed in the study area. Lithologies are sandstone, carbonaceous shale, mudstone, limestone, and the lignite. A total of 65 species of sporomorphs and 51 dinoflagellate cysts were identified. The recovered spores and pollen grains were used to establish six informal palynomorph assemblage zones, labeled as zone A – zone F, based on the first and the last occurrences of two or more species. These palynomorph assemblage zones include:(1) zone A — middle Paleocene Scabratriporites simpliformis–Bombacidites annae zone;(2) zone B — late Paleocene Foveotricolporites crassiexinus–Mauritidiites crassiexinus zone;(3) zone c — early Eocene Striatopollis catatumbus–Momipites africanus zone;(4) zone D — middle Eocene Margocolporites umuahiaensis–Gemmastephanocolporites brevicolpites zone;(5)zone E — late Eocene cicatricosisporites dorogensis–Perfotricolpites nigerianus zone;and,(6) zone F — Oligocene–early Miocene Verrucatosporites usmensis–Magnastriatites howardii zone. The erected palynozones were correlated and compared with existing biozones in subsurface, down-dip sectors of the Niger Delta Basin, with pantropical palynological zones in tropical areas of Africa, and with palynofloral provinces of northern South America. A comparison of palynozones studied in southeastern Nigeria with other international palynozones, in this study, will assist in establishing

关键词： Palynology Stratigraphy Biozonation Spores and pollen grains Dinoflagellate cysts cenozoic Niger Delta Basin

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Antidiabetic effect of chrysophyllum albidum is mediated by enzyme inhibition and enhancement of glucose uptake via 3T3-L1 adipocytes and c2c12 myotubes

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Asian Pacific Journal of Tropical Biomedicine 2020年第9期10卷 387-396页

作者： Benjamin kingsley Harley Rita Akosua Dickson isa.c kingsley a.ponsa. Robert A Ngala Dorice Berkoh Theophilus christian Fleischer Department of Pharmacognosy and Herbal Medicine School of PharmacyUniversity of Health and Allied SciencesHoGhana Department of Pharmacognosy Faculty of Pharmacy and Pharmaceutical SciencesCollege of Health SciencesKwame Nkrumah University of Science and TechnologyKumasiGhana Department of Molecular Medicine School of Medical SciencesCollege of Health SciencesKwame Nkrumah University of Science and TechnologyKumasiGhana Department of Basic and Applied Biology School of SciencesUniversity of Energy and Natural ResourcesSunyaniGhana

Objective:To investigate the in vivo and in vitro antidiabetic potential of chrysophyllum ***:The effects of oral treatment with hydro-ethanolic extract(125,250 and 500 mg/kg)of the stem bark of chrysophyllum albidum and glibenclamide for 21 d on glucose level,serum enzyme markers for liver function,lipid profile,total protein,serum urea,serum creatinine,and body weight were evaluated in experimental diabetic rats administered with 45 mg/kg of *** vitro assays including glucose uptake in c2 c12 cells and 3 T3-L1 adipose tissues,α-glucosidase andα-amylase inhibition were employed to evaluate the possible mechanism of hypoglycemic action of the *** and nitric oxide radical antioxidant activity of the extract was also ***:The increased levels of blood glucose,triglycerides,lowdensity lipoprotein,total cholesterol,serum aspartate,and alanine transaminases,creatinine,and urea in the diabetic animals were reduced significantly(Pchrysophyllum albidum *** decreased total protein and high-density lipoprotein concentrations were normalized after *** addition,the extract significantly(Pcreased the transport of glucose in 3 T3-L1 cells and c2 c12 myotubes and exhibited considerable potential to inhibitα-amylase andα-*** also demonstrated potent antioxidant action by scavenging considerably DPPH and nitric oxide ***:chrysophyllum albidum stem bark extract exhibits considerable antidiabetic effect by stimulating glucose uptake and utilization in c2 c12 myotubes and 3 T3-L1 adipocytes as well as inhibiting the activities ofα-amylase andα-glucosidase.

关键词： Antidiabetic c2c12 myotubes α-glucosidase inhibition α-amylase inhibition Glucose uptake chrysophyllum albidum

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水婴

水婴

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作者： c.·金斯利(c. kingsley)

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Buruli ulcer in Nigeria:results of a pilot case study in three rural districts

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Infectious Diseases of Poverty 2016年第1期5卷 328-336页

作者： kingsley N.Ukwaja Anthony O.Meka Alphonsus chukwuka kingsley B.Asiedu Kristina L.Huber Miriam Eddyani Joseph N.chukwu Moses c.Anyim charles c.Nwafor Daniel c.Oshi Nelson O.Madichie Ngozi Ekeke Martin Njoku Kentigern Ntana Department of Medicine Federal Teaching HospitalFMC RdAbakalikiEbonyi StateNigeria Medical Department German Leprosy and TB Relief AssociationEnuguEnugu StateNigeria St Benedict’s Tuberculosis and Leprosy Rehabilitation Hospital OgojaCross River StateNigeria Global Buruli Ulcer Initiative Department of Control of Neglected Tropical DiseasesWorld Health OrganizationGenevaSwitzerland Department of Infectious Diseases and Tropical Medicine University HospitalLudwig-Maximilians UniversityMunichGermany Mycobacteriology Unit Department of MicrobiologyInstitute of Tropical MedicineAntwerpBelgium

Background:Buruli ulcer(BU),also known as Mycobacterium ulcerans disease,is the third most common mycobacterial disease *** BU disease has been diagnosed among Nigerians in neighbouring West African countries,data on the burden of the disease in Nigeria itself are *** study aimed to assess the magnitude and epidemiology of BU in the South South region of ***:We conducted a cross-sectional survey in the Ogoja territory(comprising 31 communities).We undertook sensitisation programmes centred on BU in 10 of the *** were asked to identify community members with long-standing ulcers,who were then invited for *** also contacted traditional healers to refer their clients who had non-healing *** suspected cases had a full clinical evaluation and laboratory *** cases were given treatment in a referral hospital in the ***:We diagnosed 41 clinical BU cases;36(87.8%)of which were confirmed by quantitative polymerase chain reaction(qPcR).These 36 PcR-confirmed cases were diagnosed in a total population of 192,169 ***,the estimated crude prevalence of BU was 18.7 per 100,000 population,varying from 6.0 to 41.4 per 100,000 in the districts *** majority(66.7%)of the cases were *** 92%of the BU lesions were located on the patients’*** differences were observed between the sexes in terms of the location of the *** age of the patients ranged from four to 60 years,with a median age of 17 *** 35(100%)patients who consented to treatment completed chemotherapy as *** the treated cases,29(82.9%)needed and received *** cases healed,but 29(82.9%)had some limitations in *** with limitations in movement occurred in 18/19(94.7%)and 8/10(80.0%)of patients with lesions>15 cm(category III)and 6–15 cm in diameter(category II),*** median duration of treatment was 130(87–164)days for children and

关键词： Buruli ulcer Mycobacterium ulcerans Epidemiology case finding Endemicity Ogoja cross River State Nigeria

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Producing durable pellets from barley straw subjected to radio frequency-alkaline and steam explosion pretreatments

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International Journal of Agricultural and Biological Engineering 2014年第3期7卷 68-82页

作者： kingsley L.Iroba Lope G.Tabil Shahab Sokhansanj Venkatesh Meda Department of chemical and Biological Engineering University of SaskatchewanSaskatoon SK S7N 5A9Canada

Pelletization,a form of densification,increases bulk density and improves the convenience and accessibility of biomass feedstock due to the uniform shape and *** of biomass enhances the breakdown and accessibility of the cross-linking lignin,which acts as a binding *** this study,pelletization of radio frequency-alkaline and steam explosion pretreated barley straw was *** levels of temperature(70oc,80oc,and 90oc),five levels of the mass ratio of biomass to NaOH solution(1:4,1:5,1:6,1:7,and 1:8),one hour equilibration time,biomass screen size of 1.6 mm,1%NaOH concentration,and 20 min residence time in the radio frequency chamber were used for the radio frequency-alkaline *** levels of steam temperature(140oc,160oc,and 180oc),three levels of moisture content of 8%,30%,and 50%(mass fraction of total mass),and 5 min and 10 min exposure to steam were tested for the steam explosion *** effects of both pretreatment methods were evaluated by pelletizing the pretreated and non-pretreated barley straw samples in a single pelleting *** pellet density,tensile strength,durability,dimensional stability,and color of the pellets were *** frequency-alkaline pretreatment with the use of 1%NaOH solution and a ratio of biomass:NaOH solution of 1:8 has significant effect(Pcal *** steam exploded samples pretreated at higher temperatures(180ºc)and retention time of 10 min resulted into pellets with good physical qualities.

关键词： radio frequency steam explosion densification biomass pellets and alkaline pretreatment

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Mapping soil nutrients via different covariates combinations:theory and an example from Morocco

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Ecological Processes 2022年第1期11卷 302-318页

作者： kingsley John Yassine Bouslihim Isong Abraham Isong Lahcen Hssaini Rachid Razouk Ndiye M.Kebonye Prince c.Agyeman Vit Penížek Tereza Zádorová Department of Soil Science and Soil Protection Faculty of AgrobiologyFoodand Natural ResourcesCzech University of Life SciencesKamýcká12916500 PragueCzech Republic National Institute of Agricultural Research RabatMorocco Department of Soil Science University of CalabarCalabarNigeria

Background:Mapping of soil nutrients using different covariates was carried out in northern *** study was undertaken in response to the region’s urgent requirement for an updated soil *** aimed to test various covariates combinations for predicting the variability in soil properties using ordinary kriging and kriging with external ***:A total of 1819 soil samples were collected at a depth of 0–40 cm using the 1-km grid sampling *** were screened for their pH,soil organic matter(SOM),potassium(K_(2)O),and phosphorus(P_(2)O_(5))using standard laboratory *** attributes(T)computed using a 30-m resolution digital elevation model,bioclimatic data(c),and vegetation indices(V)were used as covariates in the *** targeted soil property was modeled using covariates separately and then combined(e.g.,pH~T,pH~c,pH~V,and pH~T+c+V).k=tenfold cross-validation was applied to examine the performance of each employed *** statistical parameter RMSE was used to determine the accuracy of different ***:The pH of the area is slightly above the neutral level with a corresponding 7.82%of SOM,290.34 ppm of K_(2)O,and 100.86 ppm of P_(2)O_(5).This was used for all the selected targeted soil *** a result,the studied soil properties showed a linear relationship with the selected ***,SOM,and K 2O presented a moderate spatial autocorrelation,while P2O5 revealed a strong *** cross-validation result revealed that soil pH(RMSE=0.281)and SOM(RMSE=9.505%)were best predicted by climatic variables.P_(2)O_(5)(RMSE=106.511 ppm)produced the best maps with climate,while K_(2)O(RMSE=209.764 ppm)yielded the best map with terrain ***:The findings suggest that a combination of too many environmental covariates might not provide the actual variability of a targeted soil *** demonstrates that specific covariates with close relationships with certain soil properties might perform bet

关键词： Soil mapping Environmental variables Agriculture Soil properties Soil management

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Morphology and strain control of hierarchical cobalt oxide nanowire electrocatalysts via solvent effect

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Nano Research 2020年第11期13卷 3130-3136页

作者： Xiuming Bu Xiongyi Liang kingsley O.Egbo Zebiao Li You Meng Quan Quan Yang Yang Li Kin Man Yu chi-Man Lawrence Wu Johnny c.Ho Department of Materials Science and Engineering City University of Hong KongKowloonHong Kong SARChina Department of Physics City University of Hong KongKowloonHong KongKowloonHong Kong SARChina State Key Laboratory of Terahertz and Millimeter Waves City University of Hong KongKowloonHong Kong SARChina

Designing highly efficient and low-cost electrocatalysts for oxygen evolution reaction is important for many renewable energy *** particular,strain engineering has been demonstrated as a powerful strategy to enhance the electrochemical performance of catalysts;however,the required complex catalyst preparation process restricts the implementation of strain ***,we report a simple self-template method to prepare hierarchical porous co_(3)O_(4)nanowires(PNWs)with tunable compressive strain via thermal-oxidation-transformation of easily prepared oxalic acid-cobalt nitrate(co(NO_(3))_(2))composite *** on the complementary theoretical and experimental studies,the selection of proper solvents in the catalyst preparation is not only vital for the hierarchical structural evolution of co_(3)O_(4) but also for regulating their compressive surface *** of the rich surface active sites and optimized electronic co d band centers,the PNWs exhibit the excellent activity and stability for oxygen evolution reaction,delivering a low overpotential of 319 mV at 10 mA·cm^(−2)in 1 M KOH with a mass loading 0.553 mg·cm^(−2),which is even better than the noble metal catalyst of RuO_(2).This work provides a cost-effective example of porous co_(3)O_(4)nanowire preparation as well as a promising method for modification of surface strain for the enhanced electrochemical performance.

关键词： hierarchical structure morphology control compressive strain solvent effect oxygen evolution reaction

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