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Insect Science 2020年第5期27卷 1125-1134页

作者： Nuria Agusti Cristina Castane irene Fraile Oscar Alomar IRTA(Institute of Agrifood Research and Technology) CabrilsBarcelonaSpain

Development of conservation biological control programs requires the identifi-cation of sources that contribute to predator colonization of *** pygmaeus(Rambur)(Hemiptera:Miridae)is an efficient polyphagous predator used in biological con-trol programs in vegetable crops in *** have developed a marking method based on spraying with a solution of the brine shrimp Artemia spp.(Anostraca:Artemidac)cysts,followed by a PCR detection of Artemia DNA to monitor *** dispersal from banker plants to tomato *** conducted in climatic chambers show that the topical application of this marking solution on *** does not significantly reduce adult longevity and that it is detected up to 6 d after the *** this Artemia solution was applied on Calendula officinalis *** plants harboring *** and maintained outdoors,Artemia DNA was still detected on 62%of the insects after6 *** conducted field applications in commercial greenhouses have confirmed the usefulness of this method to monitor *** dispersal from banker plants to a newly planted tomato *** method can be used to assess arthropod movement,being an interesting molecular approach for further improving future pest management strategies.

关键词： Artemia arthropod dispersal Calendula officinalis Macrolophus pygmaeus PCR analysis tomato crop

Refining Linked Data with Games with a Purpose

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Data Intelligence 2020年第3期2卷 417-442页

作者： irene Celino Gloria Re Calegari Andrea Fiano Cefriel Milano 20126Italy

With the rise of linked data and knowledge graphs,the need becomes compelling to find suitable solutions to increase the coverage and correctness of data sets,to add missing knowledge and to identify and remove *** approaches-mostly relying on machine learning and natural language processing techniques-have been proposed to address this refinement goal;they usually need a partial gold standard,i.e.,some“ground truth”to train automatic *** standards are manually constructed,either by involving domain experts or by adopting crowdsourcing and human computation *** this paper,we present an open source software framework to build Games with a Purpose for linked data refinement,i.e.,Web applications to crowdsource partial ground truth,by motivating user participation through fun *** detail the impact of this new resource by explaining the specific data linking“purposes”supported by the framework(creation,ranking and validation of links)and by defining the respective crowdsourcing tasks to achieve those *** also introduce our approach for incremental truth inference over the contributions provided by players of Games with a Purpose(also abbreviated as GWAP):we motivate the need for such a method with the specificity of GWAP *** crowdsourcing;we explain and formalize the proposed process,explain its positive consequences and illustrate the results of an experimental comparison with state-of-the-art *** show this resource’s versatility,we describe a set of diverse applications that we built on top of it;to demonstrate its reusability and extensibility potential,we provide references to detailed documentation,including an entire tutorial which in a few hours guides new adopters to customize and adapt the framework to a new use case.

关键词： Human computation Games with a purpose Linked data Knowledge graph Data refinement Data linking Truth inference

Home range variability,spatial aggregation,and excursions of Akodon azarae and Oligoryzomys flavescens in Pampean agroecosystems

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Integrative Zoology 2020年第5期15卷 401-415页

作者： irene GOROSITO Ailén BENÍTEZ Maria BUSCH Laboratorio de Ecología de PoblacionesFacultad de Ciencias Exactas y NaturalesUniversidad de Buenos Airesand Instituto de EcologíaGenética y Evolución de Buenos AiresConsejo Nacional de Investigaciones Científicas y TécnicasBuenos AiresArgentina Laboratorio de Ecología de Poblaciones Facultad de Ciencias Exactas y NaturalesUniversidad de Buenos AiresBuenos AiresArgentina Laboratorio de Ecología de Poblaciones Facultad de Ciencias Exactas y NaturalesUniversidad de Buenos Airesand Instituto de EcologíaGenética y Evolución de Buenos AiresConsejo Nacional de Investigaciones Científicas y TécnicasBuenos AiresArgentina

Rodents are reservoirs of various types of hantavirus,some of which are agents of hantavirus pulmonary syndrome in *** hantavirus is associated with a single rodent host species but successive spill-over events may eventually lead to host-switching and new species’becoming host of a given *** study aims to gain an understanding of the spatial ecology of two hantavirus-host species,Akodon azarae,and Oligoryzomys flavescens,by identifying factors modulating their home range sizes and stability,and by evaluating intra-and interspecific spatial aggregation for these species and a third one—Oxymycterus rufus—living in *** this,eleven capture-mark-recapture surveys were carried out,spanning 22 *** found that *** males have larger and more mobile home ranges than females,independently of the ***,males could likely have a more relevant role in the transmission of hantavirus because of their greater exposure both to a higher number of contacts between individuals and viral contamination of the ***,*** individuals showed negligible displacements of their home range through time,which could limit the range of hantavirus spread in host *** *** is host to Lechiguanas hantavirus(pathogenic to humans)this result encompasses epidemiological relevance,for it may imply the existence of local foci of ***,individuals of both species performed excursions outside their home *** events could enable hantavirus spread over distances beyond the normal range of movements and lead to new hantavirus outbreaks in formerly non-infected rodent populations,favoring the persistence of the virus in nature.

关键词： hantavirus home range intra-and interspecific contact rodent spatial ecology

Biosolid Application to Agricultural Land a Contribution to Global Phosphorus Recycle： A Review

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Pedosphere 2017年第1期27卷 1-16页

作者： Silvana irene TORRI rodrigo Studart CORRt Giancarlo RENELLA Department of Natural Resources and Environment School of Agriculture University of Buenos Aires Avenue San Martin 4453 Buenos Aires 1417 DSE (Argentina) University of Brasilia-UnB/PPGCA Campus Darcy Ribeiro Caixa Postal 04401 70910-970 DF (Brazil) Department of Agrifood Production and Environmental Sciences University of Florence Piazzale delle Caseine 18 Florence 50144 (Italy)

Phosphorus(P) is an essential nutrient required for plant *** population growth and rising global demand for food are expected to increase the demand for phosphate ***,high-quality phosphate rock reserves are progressively becoming *** of the increased pressure on P resources could be alleviated by recycling P present in ***,it is crucial to understand the dynamics of P in biosolid-amended soils,the effects of residual biosolid-borne P in soils,the way in which microorganisms may control P dynamics in biosolid-amended soils and the environmental implications of the use of biosolids as a source of *** research is needed to maximize biosolid-borne P uptake by crops and minimize its loss from biosolid-amended *** analysis of the microbiological control of P dynamics in biosolid-amended soils indicates interactions of biosolid P with other nutrients such as carbon(C) and nitrogen(N),suggesting that harmonization of the current regulation on the use of biosolids in agriculture,mainly based on total N and pollutant contents,is needed to better recycle P in agriculture.

关键词： anthropogenic P phosphate P availability P biogeocycle P uptake runoff P

Combining material characterization with single and multi-oxyanion adsorption for mechanistic study of chromate removal by cationic hydrogel

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Journal of Environmental Sciences 2011年第6期23卷 1004-1010页

作者： irene M.C.Lo Samuel C.N.Tang Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyHong KongChina

Cationic hydrogel with magnetic property was synthesized via radical polymerization and its removal capacity of chromate from contaminated water was found to be 200 mg/*** Fourier transform infrared spectroscopy（FT-IR） study,the mechanism of chromate removal by hydrogel was found to be non-specific adsorption,mainly due to ion exchange,as evidenced by the positively charged functional group,trimethyl ammonium-N＋（CH3）3,in the *** were accordingly determined by testing di？erent oxyanion adsorption onto the *** results of the chromate adsorption experiments illustrated that the amount of chromate adsorbed was nearly equal to that of the chloride released from the hydrogel,which is part of the evidence for ion *** and multi-oxyanion adsorption experiments were also performed,and it was demonstrated that ion removal was species independent,but charge dependent,another characteristic of the ion exchange *** was found that the same Langmuir model can be applied to best fit the findings of single and multi-oxyanion adsorption,which further indicates the mechanism of chromate removal is attributed to ion *** view of the above,the background anions compete for adsorption sites with chromate,evidenced by inhibitive chromate removal in the presence of background electrolytes in the batch studies,further echoing the ion exchange mechanism.

关键词： adsorption magnetic hydrogel mechanism ion exchange oxyanion

Methodology for high-quality studies on course and prognosis of inflammatory bowel disease

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World Journal of Gastroenterology 2012年第29期18卷 3800-3805页

作者： irene Modesto Giovanni Perricone Ambrogio Orlando Mario Cottone Division of Internal Medicine "Villa SofiaCervello" HospitalUniversity of Palermo790146 PalermoItaly

Inflammatory bowel diseases(IBDs) are characterized by a chronic course with an alternation of relapses and *** about prognosis are important for the patient who wants to know how the disease will affect his/her life and also for clinicians to make management *** selection of the patients is the basis for good methodological studies on the course of IBD.A great proportion of data on the course of IBD is derived from a limited number of cohort *** help to define the endpoints for clinical trials and to identify subsets of patients in whom the prognosis of the disease can be stratified according to clinical *** scientific requirements for high-quality studies on prognosis are the following:use of inception cohort,description of referral patterns,completeness of follow-up,objective outcome criteria,blind outcome assessment,adjustment for extraneous prognostic factors and statistical *** analyzed each of these requirements in studies on *** date,prospective and populationbased cohort studies are the standard for an unbiased assessment of prognosis.A better knowledge of the course of disease of chronic disorders ideally requires:(1) data from population-based studies,to avoid selection bias from referral centers in which patients with a more severe disease are usually treated;(2) inclusion of patients seen at the onset of the disease excluding misdiagnosed cases;and(3) follow-up from the onset of the disease to the end without dropouts.

关键词： Methodology Inflammatory bowel disease course Prognosis Population-based studies Prospective cohort studies

Hepatocellular Tumors:Immunohistochemical Analyses for Classification and Prognostication

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Chinese Journal of Cancer Research 2011年第4期23卷 245-253页

作者： Regina Cheuk-Lam Lo irene Oi-Lin Ng Department of Pathology and State Key Laboratory for Liver Research The University of Hong Kong

Following the classification of hepatocellular nodules by the International Working Party in 1995 and further elaboration by the International Consensus Group for Hepatocellular Neoplasia in 2009, entities under the spectrum of hepatocellular nodules have been better characterized. Research work hence has been done to answer questions such as distinguishing high-grade dysplastic nodules from early hepatocellular carcinoma (HCC), delineating the tumor cell origin of HCC, identifying its prognostic markers, and subtyping hepatocellular adenomas. As a result, a copious amount of data at immunohistochemical and molecular levels has emerged. A panel of immunohistochemical markers including glypican-3, heat shock protein 70 and glutamine synthetase has been found to be of use in the diagnosis of small, well differentiated hepatocellular tumors and particularly of HCC. The use of liver fatty acid binding protein (L-FABP), β-catenin, glutamine synthetase, serum amyloid protein and C-reactive protein is found to be helpful in the subtyping of hepatocellular adenomas. The role of tissue biomarkers for prognostication in HCC and the use of biomarkers in subclassifying HCC based on tumor cell origin are also discussed.

关键词： Hepatocellular tumors Immunohistochemical Classification

Graph Regularized L_p Smooth Non-negative Matrix Factorization for Data Representation

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IEEE/CAA Journal of Automatica Sinica 2019年第2期6卷 584-595页

作者： Chengcai Leng Hai Zhang Guorong Cai irene Cheng Anup Basu the School of Mathematics Northwest University School of Mathematics and Information Sciences Nanchang Hangkong University Nanchang 330063 China the Department of Computing Science University of Alberta the Faculty of Information Technology & State Key Laboratory of Quality Research in Chinese Medicines Macao University of Science and Technology the College of Computer Engineering Jimei University the Department of Computing Science University of Alberta

This paper proposes a Graph regularized Lpsmooth non-negative matrix factorization(GSNMF) method by incorporating graph regularization and L_p smoothing constraint, which considers the intrinsic geometric information of a data set and produces smooth and stable solutions. The main contributions are as follows: first, graph regularization is added into NMF to discover the hidden semantics and simultaneously respect the intrinsic geometric structure information of a data set. Second,the Lpsmoothing constraint is incorporated into NMF to combine the merits of isotropic(L_2-norm) and anisotropic(L_1-norm)diffusion smoothing, and produces a smooth and more accurate solution to the optimization problem. Finally, the update rules and proof of convergence of GSNMF are given. Experiments on several data sets show that the proposed method outperforms related state-of-the-art methods.

关键词： Data clustering dimensionality reduction graph regularization Lp smooth non-negative matrix factorization(SNMF)

Spatiotemporal trends of PM_(2.5) and its major chemical components at urban sites in Canada

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Journal of Environmental Sciences 2021年第5期33卷 1-11页

作者： Huanbo Wang Leiming Zhang irene Cheng Xiaohong Yao Ewa Dabek-Zlotorzynska School of Environment and Resource Southwest University of Science and TechnologyMianyang 621010China Air Quality Research Division Science and Technology BranchEnvironment and Climate Change CanadaTorontoCanada Lab of Marine Environmental Science and Ecology Ministry of EducationOcean University of ChinaQingdao 266100China Air Quality Research Division Science and Technology BranchEnvironment and Climate Change CanadaOttawaCanada

To evaluate the effectiveness of emission control regulations designed for reducing air pollution, chemically resolved PM_(2.5) data have been collected across Canada through the National Air Pollution Surveillance network in the past decade. 24-hr time integrated PM_(2.5) collected at seven urban and two rural sites during 2010-2016 were analyzed to characterize geographical and seasonal patterns and associated potential causes. Site-specific seven-year mean gravimetric PM_(2.5) mass concentrations ranged from 5.7 to 9.6 μg/m^(3). Seven-year mean concentrations of SO_(4)^(2-), NO_(3)^(-), NH_(4)^(+), organic carbon(OC), and elemental carbon(EC) were in the range of 0.68 to 1.6, 0.21 to 1.5, 0.27 to 0.71, 1.1 to 1.9, and 0.37 to 0.71 μg/m^(3), accounting for 10.8%-18.1%, 3.7%-16.7%, 4.7%-7.4%, 18.4%-21.0%, and 6.4%-10.6%, respectively, of gravimetric PM_(2.5) mass. PM_(2.5) and its five major chemical components showed higher concentrations in southeastern Canada and lower values in Atlantic Canada, with the seven-year mean ratios between the two regions being on the order of 1.7 for PM_(2.5) and 1.8-7.1 for its chemical components. When comparing the concentrations between urban and rural sites within the same region, those of SO_(4)^(2-) and NH_(4)^(+) were comparable, while those of NO_(3)^(-), OC, and EC were around 20%, 40%-50%, and 70%-80%, respectively, higher at urban than rural sites, indicating the regional scale impacts of SO_(4)^(2-) and NH_(4)^(+) and effects of local sources on OC and EC. Monthly variations generally showed summertime peaks for SO_(4)^(2-) and wintertime peaks for NO_(3)^(-), but those of NH_(4)^(+), OC, and EC exhibited different seasonality at different locations.

关键词： Fine particulate matter Aerosol chemical composition Monitoring network

Brain-derived neurotrophic factor as a potential biomarker of cognitive recovery in schizophrenia

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World Journal of Psychiatry 2013年第4期3卷 93-102页

作者： Rafael Penadés Rosa Catalán irene López-Vílchez Bárbara Arias Alexandre González-rodríguez Ana M Galán Cristóbal Gastó Psychiatry and Psychology ClinicalInstitute of Neurosciences (ICN) Hospital Clínic 08036 Barcelona Spain Departmentof Psychiatry and Psychobiology University of Barcelona 08036 Barcelona Spain Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) 08036 Barcelona Spain Centro Investigación en Red Salud Mental (CIBER-SAM) 28007 Madrid Spain Hemotherapy and Hemo-stasis Centre for Biomedical Diagnosis Hospital Clínic 08036 Barcelona Spain Department of Anthropology Faculty of Biol-ogy and Biomedicine Institute University of Barcelona 08036 Barcelona Spain

Brain-derived neurotrophic factor(BDNF) has been proposed as a biomarker of schizophrenia and, more specifically, as a biomarker of cognitive recovery. Evidence collected in this review indicates that BDNF is relevant in the pathophysiology of schizophrenia and could play a role as a marker of clinical response. BDNF has been shown to play a positive role as a marker in antipsychotic treatment, and it has been demonstrated that typical antipsychotics decrease BDNF levels while atypical antipsychotics maintain or increase serum BDNF levels. Furthermore, BDNF levels have been associated with severe cognitive impairments in patients with schizophrenia. Consequently, BDNF has been proposed as a candidate target of strategies to aid the cognitive recovery process. There is some evidence suggesting that BDNF could be mediating neurobiological processes underlying cognitive recovery. Thus, serum BDNF levels seem to be involved in some synaptic plasticity and neurotransmission processes. Additionally, serum BDNF levels significantly increased in schizophrenia subjects after neuroplasticity-based cognitive training. If positive replications of those findings are published in the future then serum BDNF levels could be definitely postulated as a peripheral biomarker for the effects of intensive cognitive training or any sort of cognitive recovery in schizophrenia. All in all, the current consideration of BDNF as a biomarker of cognitive recovery in schizophrenia is promising but still premature.

关键词： Schizophrenia Brain-derived neurotrophic factor Cognition Biomarkers