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Acta Pharmacologica Sinica 2004年第1期 100-105页

作者： Shao-hua SHI, Shu-sen ZHENG, Chang-ku JIA, You-fa ZHU, Hai-yang XIEDepartment of Hepatobiliary surgery, the First Affiliated Hospital, Medical College, zhejiang university Department of Pathology, Medical College, zhejiang university institute of surgery, zhejiang university, hangzhou 310003, china

AIM: To investigate the inhibitory effect of tea polyphenols (TP)on the transforming growth factor-pi (TGF-β1) expression in rat model of cyclosporine A (CsA)-induced chronic nephrotoxicity. METHODS: The rat model of CsA-induced chronic nephrotoxicity was used, 4 groups of rats were respectively treated with vehicle (0.1 mL·lg-1-d-1 sc), TP (80 mg·kg-1·d-1 ig), CsA (15 mg·2kg-1·d-1sc) and TP plus CsA (CsA 15 mg·kg-1·d-1 sc+TP 80 mg·kg-1·d-1 ig). At the end of day 28 of treatment, serum and urine are analyzed for creatinine clearance, kidney tissue for pathologic analysis. The TGF-β1 mRNA and its protein expression were detected by RT-PCR, immunohistochemistry, and Western blot. RESULTS: CsA-treated rats had increased renal expression of TGF-pl mRNA and its protein, compared with the vehicle- or TP- treated

关键词： tea cyclosporine A transforming growth factor-β kidney polymerase chain reaction immunohistochemistry Western blotting

Top 10 Influential Events in carbon neutrality and climate change response for 2023

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Frontiers in Energy 2024年第1期18卷 1-3页

作者： Research institute of Carbon Neutrality of Shanghai Jiao Tong university Research institute of Carbon Neutrality Shanghai Jiao Tong UniversityShanghai 200240China

In 2023, the global community intensified its efforts towards achieving carbon neutrality and addressing climate change, witnessing several impactful events. Research institute of Carbon Neutrality, Shanghai Jiao Tong university compiled the Top 10 Events (in chronological order) in the field of global carbon neutrality and climate change response for 2023, to share with readers these significant moments that document the ongoing ambition and collective efforts of human society.

关键词： neutral collective intensified

中国政治经济学年度发展报告（2023）（下）

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政治经济学评论 2024年第3期 90+207-208页

作者： Center for Studies of Contemporary Political Economy,Research institute for 21st-Century Marxism,Nankai university·university of Chinese Academy of Social Science Center for Teaching and Research on Capital,Renmin university of china National institute of Socialist Political Economy with Chinese Characteristics,Renmin university of china 南开大学·中国社会科学院大学21世纪马克思主义研究院当代政治经济学研究中心中国人民大学《资本论》教学与研究中心中国人民大学全国中国特色社会主义政治经济学研究中心

编者按2023年，高质量发展扎实推进，新质生产力加快形成，我国经济总体回升向好，圆满实现发展主要预期目标。为针对性地破解经济恢复发展中的难题，聚焦推进中国式现代化进程中的重点、难点问题，中国政治经济学界开展系统深入研究，...

编者按2023年，高质量发展扎实推进，新质生产力加快形成，我国经济总体回升向好，圆满实现发展主要预期目标。为针对性地破解经济恢复发展中的难题，聚焦推进中国式现代化进程中的重点、难点问题，中国政治经济学界开展系统深入研究，取得系列代表性成果。为准确刻画学界研究进展和轨迹，推动中国经济学理论体系的构建和完善，本刊精选议题如期奉上《中国政治经济学年度发展报告（2023）》。自2010年起，本刊连续十四年发布《中国政治经济学年度发展报告》，“年度发展报告”专栏已成为本刊标志性特色栏目。2023年报告聚焦12个专题，分为（上）（下）两篇，其中专题1—6于报告（上）篇刊登，专题7—12由报告（下）篇刊登。2023年报告（下）选题如下：

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Identification of a bi-directional promoter from Tomato yellow leaf curl china virus

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Progress in Natural Science:Materials International 2006年第3期16卷 281-286页

作者： GUAN Cuiping and ZHOU Xueping (institute of Biotechnology, zhejiang university, hangzhou 310029, china) [a]institute of Biotechnology Zhejiang University Hangzhou China

A bi-directional promoter of Tomato yellow leaf curl china virus (TYLCCNV) was obtained with the total DNA from TYLCCNV isolate Y10 infected tobacco leaves as a template. Plant expression vectors were constructed by fusing the amplified DNA fragment with the gus gene and nopaline terminator in different orientations. The vectors containing promoter fragments were transferred into leaf cells and plant stems of Nicotiana benthamiana by Agrobacterium-mediated method. Transient expression results showed that both the complementary and virion-sense promoters could drive the gus gene to express, and the GUS activity of the complementary-sense promoter was stronger than that of the virion-sense. Co-expression of the vector containing βC1 gene of TYLCCNV DNAβ with the vector containing a bi-directional promoter revealed that the βC1 protein has no impact on expression of either the virion- or the complementary-sense promoter.

关键词： Tomato yellow leaf curl china virus bi-directional promoter transient expression geminivirus.

Multiple products of B-splines used in CAD system

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Progress in Natural Science:Materials International 2006年第4期16卷 425-430页

作者： XU Huixia and WANG Guojin institute of Images and Graphics, zhejiang university, hangzhou 310027, china State Key Laboratory of CAD&CG, zhejiang university, hangzhou 310027, china [a]Institution of Images and Graphics Zhejiang University Hangzhou China [b]State key Laboratary of CAD CG Zhejiang University Hangzhou China

The function upgrade of computer aided design (CAD) system requested that the multiple product of B-spline functions should be represented as a linear combination of some suitable (usually higher-degree) B-splines. In this paper, we apply the theory of spline space and discrete B-splines to deduce the representation of the coefficients of all terms of the linear combination, which can be directly applied to software coding in system development.

关键词： computer aided design (CAD) NURBS Marsden’s identity.

POLYMERIZATION OF γ-STEARYL-α,l-GLUTAMATE N-CARBOXYANHYDRIDE USING RARE EARTH COORDINATION CATALYSTS

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Chinese Journal of Polymer Science 2000年第4期18卷 369-372页

作者： Xiao-ping Hu Jian Wu Zhi-kang Xu Lin-xian Feng institute of Polymer Science, zhejiang university, hangzhou 310027, china Department of Chemistry, zhejiang university, hangzhou 310027, china zhejiang Univ Dept Chem Hangzhou 310027 Peoples R China zhejiang Univ Inst Polymer Sci Hangzhou 310027 Peoples R China

A rare earth coordination system was first investigated as a new type of catalyst for the ring-openingpolymerization of α-amino acid N-carboxyanhydrides (NCAs). The results for the polymerization of γ-stearyl-α,L-glutamate(SLG) NCA using neodymium acetylacetonate (Nd(acac)_3)- or neodymium tris(2-ethylhexylphosphonate) (Nd(P_(204))_3)-triethylaluminum-water as catalysts were compared with those using conventional catalysts. It was found that the helicalpoly(γ-stearyl-L-glutamate) with high molecular weight as well as narrow molecular weight distribution can be obtained inthe presence of Nd(acac)_3/AlEt_3-1/2H_2O. The polymer obtained was characterized by IR and NMR spectroscopy.

关键词： Rare earth coordination catalyst Ring-opening polymerization Polypeptide Poly(γ-stearyl-α,L-glutamate)

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Two-dimensional electrophoresis analysis of proteomics based on image feature and mathematical morphology

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Science china Chemistry 2005年第4期48卷 361-367页

作者： SHEN Peng1,FAN Xiaohui2,ZENG Zhen2 & CHENG Yiyu2 1.The First Affiliated Hospital,College of Medicine,zhejiang university,hangzhou 310003,china 2.Pharmaceutical Informatics institute,zhejiang university,hangzhou 310027,china 1. The First Affiliated Hospital College of Medicine Zhejiang University 310003 Hangzhou China 2. Pharmaceutical Informatics institute Zhejiang University 310027 Hangzhou China

In this paper,a novel method to automatically detect protein spots on a two-dimensional (2-D) electrophoresis gel image is proposed to implement proteomics analysis of complex *** the basis of the identifying spots results based on color variation and spot size features,morphological feature is introduced as a new criterion to distinguish protein spots from non-protein ***-sharpening,edge-detecting and morphological feature extraction methods were consequently combined to detect protein spots on a 2-D electrophoresis gel image subject to strong *** proposed method was applied to detect the protein spots of proteomic gel images from *** cell,human kidney tissue and human *** results demonstrated that this method is more accurate and reliable than previous methods such as PDQuest 7.2 and ImageMaster 5.0 software for detecting protein spots on gel images with strong interferences.

关键词： proteomics, 2-dimensional electrophoresis, protein spot recognition, analytical chemistry for life, morphological feature, image recognition.

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Constrained Bézier curves' best multi-degree reduction in the L2-norm

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Progress in Natural Science:Materials International 2005年第9期15卷 843-850页

作者： ZHANG Renjiang 1,2 ** and WANG Guojin1(1. institute of Computer Images and Graphics, zhejiang university, hangzhou 310027, china 2. china institute of Metrology, zhejiang, hangzhou 310034, china) institute of Computer Images and Graphics Zhejiang University Hangzhou 310027 China. State Key Laboratory of CAD&CG Zhejiang University Hangzhou 310027 China. china institute of Metrology Zhejiang Hangzhou 310034 China

In computer aided geometric design, the degree reduction of the parameter curve is a key technique in data exchange and data compression. The various existing methods of degree reduction cannot decide whether the degree reduction curve satisfying the given tolerance exists beforehand, cannot give approximation of the best multi-degree reduction, or cannot provide explicit expression and error formula of the degree reduction curve. In this paper, we propose an entirely new method, which can hurdle the above flaws completely. For a given Bézier curve of degree n, we can easily decide whether a Bézier reduction curve of degree m exists, which has equal derivatives with the given curve up to （r-1）-th and （s-1）-th orders （r,s≤m） respectively at the endpoints, so the approximating error is less than the given tolerance ε in the L2-norm. If the curve exists, the explicit expression can be given.

关键词： computer aided design Bézier curve degree reduction L2-norm tolerance.

TENSOR PRODUCTS OF JACOBSON RADICALS IN NEST ALGEBRAS

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Chinese Annals of Mathematics,Series B 2003年第3期24卷 323-330页

作者： DONG ZHE Departinent of Mathematics, zhejiang university, hangzhou 310027, china. institute of Mathematics, Fudan university, Shanghai 200433, china. zhejiang Univ Dept Math Hangzhou 310027 Peoples R China Fudan Univ Inst Math Shanghai 200433 Peoples R China

This paper studies the tensor product RN RM of Jacobson radicals in nest algebras, and obtains that RN RM = {T∈B(H1 H2) : T(N M)(?)N_ M_, N∈N,M∈M}; and based on the characterization of rank-one operators in RN RM,i... 详细信息

关键词： Jacobson radical Tensor product Nest algebra

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Modeling golden section in plants

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Progress in Natural Science:Materials International 2009年第2期19卷 255-260页

作者： Lanling Zeng,Guozhao Wang institute of Computer Graphic and Image Processing,zhejiang university,hangzhou 310027,china [a]institute of Computer Graphic and Image Processing Zhejiang University Hangzhou 310027 China

Plants are complex structures,changing their shapes in response to environmental factors such as sunlight,water and neighboring plants. However,some mathematical rules can be found in their growth patterns,one of which is the golden section. The golden section can be observed in branching systems,phyllotaxis,flowers and seeds,and often the spiral arrangement of plant organs. In this study,tree,flower and fruit models have been generated by using the corresponding golden section characteristics,resulting in more natural patterns. Furthermore,the golden section can be found in the bifurcate angles of trees and lobed leaves,extending the golden section theory.

关键词： Golden section Plant morphology Plant modeling