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Feed intake pattern of broiler chickens under intermittent lighting:Do birds eat in the dark?

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Animal Nutrition 2019年第2期5卷 174-178页

作者： inês rodrigues Mingan Choct school of Environmental and Rural science University of New England

This paper reflects the results of a short experiment conducted in parallel with a larger trial which aimed to test the assumption that ’consumption of feed by broiler chickens during periods of darkness is largely negligible’. To that effect, on d 31, feeders of birds raised under intermittent lighting(IL), i.e. 1 h of light[1L]:3 h of dark(3D):1L:3D:1L:3D:1L:3D:2L:6D, were weighed at the onset and at the end of each period of darkness(or scotoperiod). Moreover, in order to compare the feeding behavior of IL birds with that of broilers raised under continuous lighting(CL, i.e, 18L:6D), their feeders were weighed in parallel and at the same time points. On d 31, feed intake of IL birds during scotoperiods represented 45% of their 24 h feed intake. Both CL and IL birds presented anticipatory feed intake prior to the long nocturnal period of darkness(6D), as well as higher feed intake right at the onset of lighting at 06:00. Feed intake of CL birds during the 6D nocturnal scotoperiod was negligible at around 2% of their total feed intake. Intermittent lighting birds exhibited excitement at the start of each hour-length scotoperiod and, within that time,ingested around 2.5 times the amount of feed ingested by CL birds. Although short, this study revealed several interesting observations which might be worth further exploring in a larger, lengthier, behaviorfocused experiment. Amongst other factors, it might be interesting to understand whether the high feed intake observed during scotoperiods for IL birds in reflective of the whole flock or rather a coping mechanism developed mainly by hierarchically lower-ranking birds to achieve their daily feed intakes requirements.

关键词： Feeding behavior Lighting program Photoperiod scotoperiod

Bioactive compounds of red grapes from Dao region(Portugal):Evaluation of phenolic and organic profile

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Asian Pacific Journal of Tropical Biomedicine 2016年第4期6卷 315-321页

作者： Luís rodrigues silva Mafalda Queiroz Health sciences Research Centre Faculty of Health sciences University of Beira Interior Department of Chemical Engineering Faculty of EngineeringUniversity of Porto Polytechnic Institute of Castelo Branco School of Health Dr.Lopes Dias Laboratory of Pharmacognosy Department of ChemistryFaculty of PharmacyUniversity of Porto

Objective:To improve the knowledge on the metabolite profile of five red grapes from D?o region(Portugal),concerning to the phenolic characteristics(coloured and non-coloured phenolics) and organic acid ***:Five red grapes collected from D?o region were *** profiles of phenolic compounds and organic acids were estimated by high-performance liquid chromatography with diode-array detection and high-performance liquid chromatography with UV detector,***:Totally 24 phenolic compounds were identified,and distributed by several classes:8 anthocyanins,1 hydroxybenzoic acid,4 hydroxycinnamic acids,1 stilbene,4flavan-3-ols,6 ***,10 organic acids were detected in all *** contents of each phenolic class and organic acids amounts varied significantly among the different grape cultivars *** principal components analysis differentiates the Touriga Nacional from the other varieties due to their high contents in anthocyanins,non-coloured phenolics and organic *** Nacional is an important red grape cultivar,highly esteemed in D?o region for its ability to produce high quality ***:The results suggest that the red grapes from D?o region present a good composition in bioactive compounds,being important for the production of wines with superior quality.

关键词： Vitis vinifera Grapes Dao region Phenolics Organic acids

Analysis of antisym metric cross-ply laminates using high-order shear deformation theories:a meshless approach

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Acta Mechanica sinica 2020年第5期36卷 1078-1098,I0003页

作者： D.E.s.rodrigues J.Belinha L.M.J.s.Dinis R.M.Natal Jorge Institute of science and Innovation in Mechanical and Industrial Engineering 4200-465 PortoPortugal Department of Mechanical Engineering School of EngineeringPolytechnic of Porto(ISEP)4200-072 PortoPortugal Department of Mechanical Engineering Faculty of EngineeringUniversity of Porto(FEUP)4200-465 PortoPortugal

For many years finite element method(FEM)was the chosen numerical method for the analysis of composite ***,in the last 20 years,the scientific community has witnessed the birth and development of several meshless methods,which are more flexible and equally accurate numerical *** meshless method used in this work is the natural neighbour radial point interpolation method(NNRPIM).In order to discretize the problem domain,the NNRPIM only requires an unstructured nodal ***,using the Voronoi mathematical concept,it enforces the nodal connectivity and constructs the background integration *** NNRPIM shape functions are constructed using the radial point interpolation *** this work,the displacement field of composite laminated plates is defined by high-order shear deformation *** the end,several antisymmetric cross-ply laminates were analysed and the NNRPIM solutions were compared with the *** obtained results show the efficiency and accuracy of the NNRPIM formulation.

关键词： Antisymmetric cross-ply laminates High-order shear deformation theories Meshless methods Naturalneighbour radial point interpolation method(NNRPIM)

Agmatine as a novel candidate for rapid-onset antidepressant response

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World Journal of Psychiatry 2021年第11期11卷 981-996页

作者： Ana Paula Valverde Anderson Camargo Ana Lúcia s rodrigues Department of Biochemistry Campus UniversitárioCenter for Biological SciencesUniversidade Federal de Santa CatarinaFlorianópolisSC 88040900Brazil

Major depressive disorder(MDD)is a disabling and highly prevalent mood disorder as well as a common cause of *** stress,inflammation,and intestinal dysbiosis have all been shown to play crucial roles in the pathophysiology of *** conventional antidepressants are widely used in the clinic,they can take weeks to months to produce therapeutic *** discovery that ketamine promotes fast and sustaining antidepressant responses is one of the most important breakthroughs in the pharmacotherapy of ***,the adverse psychomimetic/dissociative and neurotoxic effects of ketamine discourage its chronic ***,agmatine,an endogenous glutamatergic modulator,has been postulated to elicit fast behavioral and synaptogenic effects by stimulating the mechanistic target of rapamycin complex 1 signaling pathway,similar to ***,recent evidence has demonstrated that the modulation of the NLR family pyrin domain containing 3 inflammasome and gut microbiota,which have been shown to play a crucial role in the pathophysiology of MDD,may also participate in the antidepressant-like effects of both ketamine and *** review seeks to provide evidence about the mechanisms that may underlie the fast antidepressant-like responses of agmatine in preclinical *** the anti-inflammatory properties of agmatine,it may also be further investigated as a useful compound for the management of MDD associated with a pro-inflammatory ***,the fast antidepressant-like response of agmatine noted in animal models should be investigated in clinical studies.

关键词： Agmatine Fast-acting antidepressants Ketamine Major depressive disorder Microbiota-gut-brain axis Neuroinflammation

Comnutational Models for New Fiber Ootic Tweezers

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Photonic sensors 2013年第1期3卷 57-60页

作者： R. s. rodrigues RIBEIRO P. A. s. JORGE A. GUERREIRO INEsC-TEC (coordinated bv INEsC Porto) Rua do Campo Alegre 687. 4169 007 Porto Portugal Departamento de Fisica e Astronomia Faculdade de Ci&ncias Universidade do Porto Portugal

This paper discusses the calculation of the trapping forces in optical tweezers using a combination of the finite differences time domain （FDTD） method and the Lorentz force on electric dipoles. The results of 2D si... 详细信息

关键词： Optical tweezers optical fiber single cell FDTD electromagnetic force biosensors

sARs-CoV-2 consequences for mental health:Neuroinflammatory pathways linking COVID-19 to anxiety and depression

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World Journal of Psychiatry 2022年第7期12卷 874-883页

作者： Anna Julie de Mello Morgana Moretti Ana Lúcia s rodrigues Department of Biochemistry Universidade Federal de Santa CatarinaFlorianópolis 88040-200Brazil

The coronavirus disease 2019(COVID-19)pandemic has been linked to an increased prevalence of mental health disorders,particularly anxiety and ***,the COVID-19 pandemic has caused stress in people worldwide due to several factors,including fear of infection;social isolation;difficulty in adapting to new routines;lack of coping methods;high exposure to social media,misinformation,and fake reports;economic impact of the measures implemented to slow the contagion and concerns regarding the disease ***-19 patients have elevated levels of pro-inflammatory cytokines,such as interleukin(IL)-1β,IL-6,and tumor necrosis factor-α,and other inflammation-related ***,invasion of the central nervous system by the novel severe acute respiratory syndrome coronavirus 2(sARs-CoV-2)may potentially contribute to neuroinflammatory alterations in infected ***,a consequence of psychological stress due to the COVID-19 pandemic,may also play a role in the development of anxiety and depressive symptoms in the general *** that neuroinflammation plays a significant role in the pathophysiology of depression and anxiety,this study investigated the effects of sARs-CoV-2 on mental health and focused on the impact of the COVID-19 pandemic on the neuroinflammatory pathways.

关键词： Anxiety disorders COVID-19 pandemic Depression Mental health Neuroinflammation stress

Neutropenic Fever in Lung Cancer:Clinical Aspects Related to Mortality and Antibiotic Failure

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中国肺癌杂志 2021年第11期24卷 764-769页

作者： inês rodrigues Luísa NAsCIMENTO Ana Cláudia PIMENTA sara RAIMUNDO Bebiana CONDE Ana FERNANDEs Pulmonology Department Centro Hospitalar Trás-os-Montes e Alto DouroVila RealPortugal

Background and objectives:Lung cancer(LC)is the leading cause of cancer *** treated with chemotherapy are at risk of developing chemotherapy-induced febrile neutropenia(FN),a potentially life-threatening *** aims of this study were(1)to characterize FN admissions of patients with LC in a pulmonology department,and(2)to determine associations between patient profiles,first-line antibiotic failure(FLAF)and ***:Retrospective observational case-series,based on the analysis of medical records of LC patients that required hospitalization due to chemotherapy-induced ***:A total of 42 cases of FN were revised,corresponding to 36 patients,of which 86.1%were male,with a mean age of 66.71±9.83 *** patients had a performance status(Ps)equal or less than 1,and metastatic disease was present in 40.5%(n=17).Respiratory tract infections accounted for 42.9%(n=18)of FN cases,and multidrug-resistant staphylococcus aureus was the most isolated *** mortality rate was 16.7%(n=7),and the FLAF was 26.2%(n=11).Mortality was associated with a Ps≥2(P=0.011),infection by a Gram-negative agent(P=0.001)and severe anemia(P=0.048).FLAF was associated with longer hospitalizations(P=0.020),Ps≥2(P=0.049),respiratory infections(P=0.024),and infection by a Gram-negative(P=0.003)or multidrug-resistant agent(P=0.014).Conclusions:Lower Ps,severe anemia,and infections by Gram-negative or multi-resistant agents seem to be associated with worse outcomes in FN patients.

关键词： Febrile neutropenia First-line antibiotic failure Lung neoplasms Mortality

Current perspectives on the antidepressant-like effects of guanosine

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Neural Regeneration Research 2016年第9期11卷 1411-1413页

作者： Luis E.B.Bettio Joana Gil-Mohapel Ana Lucia s.rodrigues Department of Biochemistry Center of Biological Sciences Federal University of Santa Catarina Florianopolis-SC Brazil Division of Medical sciences and UBC Island Medical Program University of Victoria Victoria BC V8W 2Y2 Canada

Purines have a recognized importance as intercellular mes- sengers. These molecules play an important role in the de- velopment and maintenance of the central nervous system （CNs）, as well as in its response to pathological conditions. Both adenine and guanine-based purines can be released from astrocytes, where they play a relevant role as extracel- lular signaling molecules. Particularly, the nucleoside gua- nosine has been proposed as an extracellular molecule that regulates the response of CNs to damage. Following injury, this nucleoside attains high concentrations in the extracel- lular space, where it activates multiple signaling pathways.

关键词： Current perspectives on the antidepressant-like effects of guanosine

Foliar application of rare earth elements on soybean(Glycine max(L)):Effects on biometrics and characterization of phytotoxicity

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Journal of Rare Earths 2020年第10期38卷 1131-1139,I0005页

作者： Eduardo s.rodrigues Gabriel s.Montanha Joao P.R.Marques Eduardo de Almeida Lauren N.M.Yabuki Amauri A.Menegario Hudson W.Pereira de Carvalho Laboratory of Nuclear Instrumentation(LIN) Center for Nuclear Energy in Agriculture(CENA)University of Sao Paulo(USP)PiracicabaSP13416-000Brazil Environmental studies Center Sao Paulo State University(UNESP)Rio ClaroSP13506-900Brazil

This study aims at investigating the effects of foliar application of aqueous solutions of La3+and Ce3+nitrates on soybean plants(Glycine max).First,we observe that Triton HW 1000 surfactant at 0.01 vol%reduces droplets contact angle and increases their drying *** greenhouse conditions,the foliar treatments do not affect chlorophyll content,plant height,number of leaves,number of pods,number of seeds per pod,and average seed ***,the treatments induce phytotoxicity since foliar injuries appear after the *** X-ray fluorescence spectroscopy combined to scanning electron microscopy shows that the leaf lesions are positively correlated to accumulation of Ce and La on the leaf surface and also promote structural alteration to the epidermal cells.X-ray absorption near edge structure shows that the La and Ce nitrates are partially bio transformed into oxides by the leaves which might explain the harmful effects.

关键词： Leaf fertilization Rare earth elements soybean X-ray fluorescence spectroscopy X-ray absorption spectroscopy