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Genome-wide identification and spatiotemporal expression profiling of zinc finger SWIM domain-containing protein family genes

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Zoological Research 2023年第3期44卷 663-674页

作者： imtiaz ul hassan Hafiz Mamoon Rehman Ziran Liu Liangji Zhou Muhammad Kaleem Samma Chengdong Wang Zixin Rong Xufeng Qi Dongqing Cai Hui Zhao Key Laboratory for Regenerative Medicine Ministry of EducationSchool of Biomedical SciencesFaculty of MedicineThe Chinese University of Hong KongHong Kong SARChina Centre for Agricultural Biochemistry and Biotechnology(CABB) University of Agriculture FaisalabadFaisalabad 38000Pakistan Qingdao Municipal Center for Disease Control and Prevention QingdaoShandong 266034China Key Laboratory of Regenerative Medicine of Ministry of Education Department of Developmental&Regenerative BiologyJinan UniversityGuangzhou 511436China Department of Biology and Chemistry City University of Hong KongHong Kong SARChina Department of Gene Technology School of Engineering Sciences in ChemistryBiotechnology and Health(CBH)KTH Royal Institute of Technology10691 StockholmSweden Kunming Institute of Zoology-The Chinese University of Hong Kong(KIZ-CUHK)Joint Laboratory of Bioresources and Molecular Research of Common Diseases Hong Kong SARChina Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics The Chinese University of Hong KongHong Kong SARChina

The biological function of the novel zinc-finger SWIM domain-containing protein family(ZSWIM)during embryonic development remains ***,we conducted a genome-wide analysis to explore the evolutionary processes of the ZSWIM gene family members in mice,Xenopus tropicalis,zebrafish,and *** identified nine putative ZSWIM genes in the human and mouse genome,eight in the Xenopus genome,and five in the zebrafish *** on multiple sequence alignment,three members,ZSWIM5,ZSWIM6,and ZSWIM8,demonstrated the highest homology across all four *** available RNA sequencing(RNAseq)data,ZSWIM genes were found to be widely expressed across different tissues,with distinct tissuespecific *** identify the functions of the ZSWIM protein family during embryogenesis,we examined temporal and spatial expression patterns of zswim family genes in Xenopus *** real-time polymerase chain reaction(qRT-PCR)revealed that each member had a distinct expression ***-mount in situ hybridization showed that both zswim1 and zswim3 were maternally expressed genes;zswim5 and zswim6were expressed throughout embryogenesis and displayed dynamic expression in the brain,eyes,somite,and bronchial arch at the late tailbud stages;zswim7 was detected in the eye area;zswim8 showed a dynamic expression pattern during the tailbud stages,with expression detected in the brain,eyes,and somite;zswim9 was faintly expressed throughout embryonic *** study provides a foundation for future research to delineate the functions of ZSWIM gene members.

关键词： ZSWIM gene family Xenopus Gene expression Phylogenetic analysis Bioinformatics

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Modeling the dynamical behavior of the interaction of T-cells and human immunodeficiency virus with saturated incidence

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Communications in Theoretical Physics 2024年第3期76卷 1-14页

作者： Salah Boulaaras Rashid Jan Amin Khan Ali Allahem imtiaz Ahmad Salma Bahramand Department of Mathematics College of ScienceQassim UniversityBuraydah51452Saudi Arabia Institute of Energy Infrastructure(IEI) Department of Civil EngineeringCollege of EngineeringUniversiti Tenaga Nasional(UNITEN)Putrajaya CampusJalan IKRAM-UNITEN43000 KajangSelangorMalaysia Department of Mathematics University of SwabiSwabi 23561Pakistan Department of Mathematics College of SciencesQassim UniversitySaudi Arabia Institute of Informatics and Computing in Energy(IICE) Universiti Tenaga NasionalKajangSelangorMalaysia Department of Political Science Bacha Khan University CharsaddaCharsadda 24420KPK Pakistan

In the last forty years,the rise of HIV has undoubtedly become a major concern in the field of public health,imposing significant economic burdens on affected ***,it becomes imperative to undertake comprehensive investigations into the mechanisms governing the dissemination of HIV within the human *** this work,we have devised a mathematical model that elucidates the intricate interplay between CD4^(+)T-cells and viruses of HIV,employing the principles of fractional *** production rate of CD4^(+)T-cells,like other immune cells depends on certain factors such as age,health status,and the presence of infections or ***,we incorporate a variable source term in the dynamics of HIV infection with a saturated incidence rate to enhance the precision of our *** introduce the fundamental concepts of fractional operators as a means of scrutinizing the proposed HIV *** facilitate a deeper understanding of our system,we present an iterative scheme that elucidates the trajectories of the solution pathways of the *** show the time series analysis of our model through numerical findings to conceptualize and understand the key factors of the *** addition to this,we present the phase portrait and the oscillatory behavior of the system with the variation of different input *** information can be utilized to predict the long-term behavior of the system,including whether it will converge to a steady state or exhibit periodic or chaotic oscillations.

关键词： HIV infection fractional-calculus dynamics of HIV iterative scheme dynamical behaviour mathematical model fractional derivatives

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Accelerated Particle Swarm Optimization Algorithm for Efficient Cluster Head Selection in WSN

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Computers, Materials & Continua 2024年第6期79卷 3585-3629页

作者： imtiaz Ahmad Tariq Hussain Babar Shah Altaf Hussain Iqtidar Ali Farman Ali Institute of Computer Sciences and Information Technology The University of AgriculturePeshawarPakistan School of Computer Science and Technology Zhejiang Gongshang UniversityHangzhouChina College of Technological Innovation Zayed UniversityDubaiUnited Arab Emirates School of Computer Science and Technology Chongqing University of Posts and TelecommunicationsChongqing400065China Department of Applied AI School of ConvergenceCollege of Computing and InformaticsSungkyunkwan UniversitySeoul03063South Korea

Numerous wireless networks have emerged that can be used for short communication ranges where the infrastructure-based networks may fail because of their installation and *** of them is a sensor network with embedded sensors working as the primary nodes,termed Wireless Sensor Networks(WSNs),in which numerous sensors are connected to at least one Base Station(BS).These sensors gather information from the environment and transmit it to a BS or gathering *** have several challenges,including throughput,energy usage,and network lifetime *** strategies have been applied to get over these *** may,therefore,be thought of as the best way to solve such ***,it is crucial to analyze effective Cluster Head(CH)selection to maximize efficiency throughput,extend the network lifetime,and minimize energy *** paper proposed an Accelerated Particle Swarm Optimization(APSO)algorithm based on the Low Energy Adaptive Clustering Hierarchy(LEACH),Neighboring Based Energy Efficient Routing(NBEER),Cooperative Energy Efficient Routing(CEER),and Cooperative Relay Neighboring Based Energy Efficient Routing(CR-NBEER)*** the help of APSO in the implementation of the WSN,the main methodology of this article has taken *** simulation findings in this study demonstrated that the suggested approach uses less energy,with respective energy consumption ranges of 0.1441 to 0.013 for 5 CH,1.003 to 0.0521 for 10 CH,and 0.1734 to 0.0911 for 15 *** sending packets ratio was also raised for all three CH selection scenarios,increasing from 659 to *** number of dead nodes likewise dropped for the given combination,falling between 71 and *** network lifetime was deemed to have risen based on the results found.A hybrid with a few valuable parameters can further improve the suggested APSO-based *** to underwater,WSN can make use of the proposed *** overall results have been evaluated and

关键词： Wireless sensor network cluster head selection low energy adaptive clustering hierarchy accelerated particle swarm optimization

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Combinative approach of transzonular triamcinolonemoxifloxacin and perioperative drops to minimize postoperative complications of cataract surgery

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 845-851页

作者： Behnam Rabiee Muhamad Festok Michael Gaspari Abid Haseeb Aaila Chaudhry Layla Kamoun imtiaz Chaudhry Iftikhar Chaudhry Department of Ophthalmology Trinity Health Mid-AtlanticNazareth HospitalPhiladelphiaPA 19020USA IC Laser Eye Care BensalemPA 19020USA

AIM: To investigate the effectiveness of combinationtherapy with transzonular triamcinolone-moxifloxacin andconventional perioperative drops in reducing postoperativecomplications of cataract surgery. METHODS: Electronic medical records of cataractsurgery patients (single surgeon) were reviewed fromJanuary 2018 to September 2021. The rate of postoperativecomplications including prolonged and/or recurrentpostoperative inflammation, endophthalmitis, cystoid macularedema (CME), and intraocular pressure (IOP) was comparedbetween the patients receiving combinative therapy andpatients receiving drops only. RESulTS: Totally 596 patients and 1057 eyes(Combinative-Therapy group 493 and Drop-Only group 564)were included in this study. Using combination therapyreduced the relative risk of postoperative inflammationby 26.9% (16.6% Combinative-Therapy vs 22.7% Drop-Only, P=0.013). The incidence of endophthalmitis was 0in Combinative-Therapy group vs 0.5% in Drop-Only group(relative risk reduction 100%), although not statisticallysignificant (P=0.10). The incidence of severe IOP spikeswas not significantly different between Combinative-Therapy (2.4%) and Drop-Only (1.6%) groups (P=0.33).The relative risk of postoperative CME was 51.4% less inthree months follow up visit in Combinative-Therapy group,although not statistically significant (P=0.07). The visualoutcome 1-month postop. (best corrected visual acuity) wassignificantly better in Combinative-Therapy (logMAR 0.10)compared to Drop-Only (logMAR 0.14) groups (P=0.02) whilethe baseline visual acuity was not significantly different. CONCLUSION: The combinative approach oftranszonular triamcinolone-moxifloxacin plus perioperativeeyedrops is an effective method to minimize postoperativeinflammation, with better visual outcomes. It couldpotentially reduce the risk of postoperative endophthalmitisand CME (near-significant P-values;larger studies couldanalyze better considering low incidence).

关键词： cataract endophthalmitis cystoid macular edema postoperative complications transzonular injection

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Deep-learning-empowered synthetic dimension dynamics: morphing of light into topological modes

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Advanced Photonics 2024年第2期6卷 61-68页

作者： Shiqi Xia Sihong Lei Daohong Song Luigi Di Lauro imtiaz Alamgir Liqin Tang Jingjun Xu Roberto Morandotti Hrvoje Buljan Zhigang Chen Nankai University TEDA Institute of Applied Physics School of Physics The MOE Key Laboratory of Weak-Light Nonlinear Photonics Shanxi University Collaborative Innovation Center of Extreme Optics INRS-EMT University of Zagreb Department of PhysicsFaculty of Science

Synthetic dimensions(SDs) opened the door for exploring previously inaccessible phenomena in high-dimensional space. However, construction of synthetic lattices with desired coupling properties is a challenging and unintuitive task. Here, we use deep learning artificial neural networks(ANNs) to construct lattices in real space with a predesigned spectrum of mode eigenvalues, and thus to validly design the dynamics in synthetic mode dimensions. By employing judiciously chosen perturbations(wiggling of waveguides at desired frequencies), we show resonant mode coupling and tailored dynamics in SDs. Two distinct examples are illustrated: one features uniform synthetic mode coupling, and the other showcases the edge defects that allow for tailored light transport and confinement. Furthermore, we demonstrate morphing of light into a topologically protected edge mode with modified Su–Schrieffer–Heeger photonic lattices. Such an ANN-assisted construction of SDs may advance toward “utopian networks,” opening new avenues for fundamental research beyond geometric limitations as well as for applications in mode lasing,optical switching, and communication technologies.

关键词： synthetic dimensions deep learning mode manipulation topological mode morphing photonic lattices

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DeepSVDNet:A Deep Learning-Based Approach for Detecting and Classifying Vision-Threatening Diabetic Retinopathy in Retinal Fundus Images

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Computer Systems Science & Engineering 2024年第2期48卷 511-528页

作者： Anas Bilal Azhar Imran Talha imtiaz Baig Xiaowen Liu Haixia Long Abdulkareem Alzahrani Muhammad Shafiq College of Information Science and Technology Hainan Normal UniversityHaikou571158China Department of Creative Technologies Air UniversityIslamabadPakistan School of Life Science and Technology University of Electronic Science and Technology of China UESTCChengduChina School of Science and Technology University of Management and Technology UMTLahorePunjabPakistan Faculty of Computer Science&Information Technology Al Baha UniversityAl BahaSaudi Arabia School of Information Engineering Qujing Normal UniversityQujingChina

Artificial Intelligence(AI)is being increasingly used for diagnosing Vision-Threatening Diabetic Retinopathy(VTDR),which is a leading cause of visual impairment and blindness ***,previous automated VTDR detection methods have mainly relied on manual feature extraction and classification,leading to *** paper proposes a novel VTDR detection and classification model that combines different models through majority *** proposed methodology involves preprocessing,data augmentation,feature extraction,and classification *** use a hybrid convolutional neural network-singular value decomposition(CNN-SVD)model for feature extraction and selection and an improved SVM-RBF with a Decision Tree(DT)and K-Nearest Neighbor(KNN)for *** tested our model on the IDRiD dataset and achieved an accuracy of 98.06%,a sensitivity of 83.67%,and a specificity of 100%for DR detection and evaluation tests,*** proposed approach outperforms baseline techniques and provides a more robust and accurate method for VTDR detection.

关键词： Diabetic retinopathy(DR) fundus images(FIs) support vector machine(SVM) medical image analysis convolutional neural networks(CNN) singular value decomposition(SVD) classification

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Robust graph‐based localization for industrial Internet of things in the presence of flipping ambiguities

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CAAI Transactions on Intelligence Technology 2023年第4期8卷 1140-1149页

作者： Mian imtiaz ul Haq Ruhul Amin Khalil Muhannad Almutiry Ahmad Sawalmeh Tanveer Ahmad Nasir Saeed Faculty of Electrical Engineering Swedish College of Engineering and TechnologyWah CanttPakistan Department of Electrical Engineering Faculty of Electrical and Computer EngineeringUniversity of Engineering and TechnologyPeshawarPakistan Department of Electrical Engineering Remote Sensing UnitNorthern Border UniversityArarSaudi Arabia Data Science and Artificial Intelligence Department‐College of Science and Information Technology Irbid National UniversityIrbadJordan Innovation Education and Research Center for On‐Device AI Software(Bk21) Department of Computer Science and EngineeringChungnam National UniversityDaejeonRepublic of Korea Department of Electrical and Communication Engineering United Arab Emirates University(UAEU)Al AinUnited Arab Emirates

Localisation of machines in harsh Industrial Internet of Things(IIoT)environment is necessary for various ***,a novel localisation algorithm is proposed for noisy range measurements in IIoT *** position of an unknown machine device in the network is estimated using the relative distances between blind machines(BMs)and anchor machines(AMs).Moreover,a more practical and challenging scenario with the erroneous position of AM is considered,which brings additional uncertainty to the final position ***,the AMs selection algorithm for the localisation of BMs in the IIoT network is *** those AMs will participate in the localisation process,which increases the accuracy of the final location ***,the closed‐form expression of the proposed greedy successive anchorization process is derived,which prevents possible local convergence,reduces computation,and achieves Cramér‐Rao lower bound accuracy for white Gaussian measurement *** results are compared with the state‐of‐the‐art and verified through numerous simulations.

关键词： Cramér‐Rao lower bound greedy successive anchorization industrial internet of things localization

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An Effective Runge-Kutta Optimizer Based on Adaptive Population Size and Search Step Size

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Computers, Materials & Continua 2023年第9期76卷 3443-3464页

作者： Ala Kana imtiaz Ahmad Department of Computer Engineering College of Engineering and PetroleumKuwait UniversityKuwait CityKuwait

A newly proposed competent population-based optimization algorithm called RUN,which uses the principle of slope variations calculated by applying the Runge Kutta method as the key search mechanism,has gained wider interest in solving optimization ***,in high-dimensional problems,the search capabilities,convergence speed,and runtime of RUN *** work aims at filling this gap by proposing an improved variant of the RUN algorithm called the *** size plays a vital role in both runtime efficiency and optimization effectiveness of metaheuristic *** the original RUN where population size is fixed throughout the search process,Adaptive-RUN automatically adjusts population size according to two population size adaptation techniques,which are linear staircase reduction and iterative halving,during the search process to achieve a good balance between exploration and exploitation *** addition,the proposed methodology employs an adaptive search step size technique to determine a better solution in the early stages of evolution to improve the solution quality,fitness,and convergence speed of the original ***-RUN performance is analyzed over 23 IEEE CEC-2017 benchmark functions for two cases,where the first one applies linear staircase reduction with adaptive search step size(LSRUN),and the second one applies iterative halving with adaptive search step size(HRUN),with the original *** promote green computing,the carbon footprint metric is included in the performance evaluation in addition to runtime and *** results based on the Friedman andWilcoxon tests revealed that Adaptive-RUN can produce high-quality solutions with lower runtime and carbon footprint values as compared to the original RUN and three recent ***,with its higher computation efficiency,Adaptive-RUN is a much more favorable choice as compared to RUN in time stringent applications.

关键词： Optimization Runge Kutta(RUN) metaheuristic algorithm exploration exploitation population size adaptation adaptive search step size

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A comprehensive physical insight about thermo physical aspects of Carreau fluid flow over a rotated disk of variable thickness by implementing finite difference approach

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Propulsion and Power Research 2022年第1期11卷 143-153页

作者： Sardar Bilal imtiaz Ali Shah Department of Mathematics AIR UniversityP.A.F ComplexSector E-9P.O.44000IslamabadPakistan

Present communication is devoted to analyze thermal characteristics of Carreau liquid flowing on variably thickened non-uniformly rotating *** formulation is constructed in view of complex coupled partial differential ***,boundary layer approach is executed for comprehensive examination of under consideration phenomenon with in boundary layer ***’s transformation is capitalized to convert the attained PDE’s into ordinary differential equations *** of attained ODE’s system is solved numerically by implementing Keller-Box *** of protuberant involved parameters on momentum and thermal distributions is illustrated through *** addition,impact of flow concerning parameters on wall shear stress and thermal flux is also *** assurance of present finding is done by making agreement with published results and by restricting considered problem to Newtonian ***,we observed that radially and tangentially directed wall drag lessen with growing magnitude of power law exponent ***,the consequence of disk thickness parameter grows stresses along radial direction whereas opposite behavior is depicted in case of tangentially directed friction and heat flux factors.

关键词： Carreau viscosity model Rotating disk Non-uniform thickness Keller-Box method

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Effects of biomechanical parameters of spinal manipulation: A critical literature review

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Journal of Integrative Medicine 2022年第1期20卷 4-12页

作者： Giles Gyer Jimmy Michael James Inklebarger imtiaz Ibne Alam Department of Clinical Skills the London College of Osteopathic MedicineBoston PlaceLondon NW1United Kingdom Department of Pharmacy Stamford University BangladeshDhaka 1217Bangladesh

Spinal manipulation is a manual treatment technique that delivers a thrust,using specific biomechanical parameters to exert its therapeutic *** parameters have been shown to have a unique dose-response relationship with the physiological responses of the *** far,however,there has not been a unified approach to standardize these biomechanical *** fact,it is still undetermined how they affect the observed clinical outcomes of spinal *** study,therefore,reviewed the current body of literature to explore these dosage parameters and evaluate their significance,with respect to physiological and clinical *** the experimental studies reviewed herein,it is evident that the modulation of manipulation’s biomechanical parameters elicits transient physiological responses,including changes in neuronal activity,electromyographic responses,spinal stiffness,muscle spindle responses,paraspinal muscle activity,vertebral displacement,and segmental and intersegmental acceleration ***,to date,there have been few clinical trials that tested the therapeutic relevance of these *** addition,there were some inherent limitations in both human and animal models due to the use of mechanical devices to apply the *** studies evaluating the effects of varying biomechanical parameters of spinal manipulation should include clinicians to deliver the therapy in order to explore the true clinical significance of the dose-response relationship.

关键词： Spinal manipulation Biomechanical characteristics Biomechanical parameters Dosage Force-time profile

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