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Overlap of orthorexia,eating attitude and psychological distress in some Italian and Spanish university students

World Journal of Psychiatry 2022年第10期12卷 1298-1312页

作者： Paola Aiello Elisabetta Toti Débora Villaño Anna Raguzzini ilaria Peluso Department of Physiology and Pharmacology“V.Erspamer” Sapienza UniversityRome 00185Italy Research Centre for Food and Nutrition Council for Agricultural Research and EconomicsRome 00178Italy Food Science and Technology Department UCAMMurcia 30107Spain

BACKGROUND Orthorexia nervosa(ON)is the persistent concern of maintaining the self-imposed diet to improve one's *** factors have been associated to ON in university *** To assess the prevalence of ON in Italian and Spanish university students in relation to eating attitude and psychological distress,and the possible overlaps between ON(evaluated with different scored questionnaires from the originally proposed ORTO-15),distress and risk of eating *** This study was carried out on 160 students recruited at La Sapienza University of Rome and at the Catholic University of *** were administered to evaluate ON(ORTO-15 and sub-scores),body concerns(Multidimensional Body-Self Relations Questionnaire,MBSRQ,and Body Uneasiness test,BUT),psychological distress(Kessler Psychological Distress Scale,K10),physical activity(International Physical Activity Questionnaire,IPAQ),eating attitude(Eating Attitudes Test,EAT-26)and malnutrition(Starvation Symptom Inventory,SSI).Sex differences,within the same country,and differences between Italian and Spanish students,within the same sex,were *** The ORTO-15 positive subjects,assessed with the originally proposed cut-off,were above 70%in both Italian and Spanish students,with a higher prevalence in the Spanish sample(Italian females 76.3%,Italian males 70.7%;Spanish females 97.0%,Spanish males 96.3%).According to ORTO-7,about 30%of Italian and 48%of Spanish students were positive to ON with no significant sex *** excluding students underweight(UW),overweight(OW)or obese(OB),as well as those potentially at risk of eating disorders or presenting mild,moderate and severe distress,in the resultant normal weight(NW)-K10neg-EAT-26neg subgroup,we did not find many correlations observed in the whole sample,including those between ORTO scores and BUT,SSI,Total MBSRQ and some of its ***,ORTO-7 resulted in the only ON score unrelated with Body Mass Index,MBS

关键词： Diet Exercise Food avoidance Other Specified Feeding and Eating Disorder Lifestyle

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Asymptotic Formulae for Multivariate Kantorovich Type Generalized Sampling Series

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Acta Mathematica Sinica,English Series 2011年第7期27卷 1247-1258页

作者： Carlo BARDARO ilaria MANTELLINI Dipartimento di Matematica e Informatica Universitd di Perugia Via Vanvitelli 1 06123 Perugia Italy

In this paper an asymptotic formula of Voronovskaja type for a multivariate extension of the Kantorovich generalized sampling series is given. Moreover a quantitative version in terms of some moduli of smoothness is established. Finally some particular examples of kernels are discussed, as the Bochner-Riesz kernel and the multivariate splines.

关键词： Voronovskaja-type formula moments multivariate Kantorovich generalized sampling series Peetre K-functional

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Spinterface:A new platform for spintronics

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Nano Materials Science 2019年第3期1卷 149-155页

作者： ilaria Bergenti Valentin Dediu Institute of Nanostructured Materials ISMN National Research Council CNR40129BolognaItaly CNR-ISMN Bologna Via P.Gobetti 10140129BolognaItaly

Since its discovery in early 2000’s Molecular Spintronics has developed in an established and fructuous research field,achieving a number of outstanding results and unveiling unusual spintronic *** the most mysterious device element,the interface,in molecular spintronics has on contrary received and enormous attention and even gained a special nickname–the *** on significant efforts of many research groups worldwide it has been established its critical role in defining the main functionalities of molecular spintronic *** the spinterface was found to control the properties of the both components constituting the interface,not only those of the molecular layer but surprisingly also those of the magnetic *** paper aims to overview the most striking spinterface properties and to highlight the possibilities to promote new device paradigms based on interfacial modulation.

关键词： Molecular spintronics Ferromagnetism Spin polarization Hybridization organic semiconductors

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Genetic analysisofsuicide:asamplestudyinTuscany(CentralItaly)

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Forensic Sciences Research 2022年第4期7卷 790-797页

作者： Martina Focardi Barbara Gualco Vilma Pinchi Norelli Gian-Aristide Regina Rensi Elisabetta Pelo ilaria Carboni Ugo Ricci Division of Genetic Diagnostics University Hospital“Careggi”FlorenceItaly

Many studies have examined the genetic contribution to ***,data on suicide in the Italian population are *** therefore aimed to address this gap by investigating a cohort of 111 Italians for whom a verdict of suicide had been declared in court in Florence,Italy between 2007 and *** cohort included 86 men and 25 *** samples were obtained from tissues or blood,and 22 genes from multiple neurobiological pathways previously shown to be associated with the pathogenesis of suicide were ***-generation sequencing was used to compare these gene sequences with those from a large,normal *** this study,we identified 19 gene variants that were present at significantly lower frequencies in our Italian cohort than in the general *** addition,four missense mutations were identified in four different genes:Monoamine Oxidase A(MAOA),5-Hydroxytryptamine Receptor 2 A(HTR2A),Sodium Voltage-Gated Channel Alpha Subunit 8(SCN8A),and Nitric Oxide Synthase 3(NOS3).Our study identified several potential genetic links with suicide in a cohort of Italians and supports a relationship between specific genetic variants and suicidal behaviour in this population.

关键词： Forensic sciences forensic genetics suicide MAOA HTR2A SCN8A NOS3

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Impaired coagulation,liver dysfunction and COVID-19:Discovering an intriguing relationship

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World Journal of Gastroenterology 2022年第11期28卷 1102-1112页

作者： Damiano D'Ardes Andrea Boccatonda Giulio Cocco Stefano Fabiani ilaria Rossi Marco Bucci Maria Teresa Guagnano Cosima Schiavone Francesco Cipollone “Clinica Medica”Institute Department of Medicine and Aging Sciences“G.D’Annunzio”University of Chieti-PescaraChieti 66100Italy Unit of Ultrasound “G.D’Annunzio”University of Chieti-PescaraChieti 66100Italy

Coronavirus disease 2019(COVID-19)is,at present,one of the most relevant global health *** the literature hepatic alterations have been described in COVID-19 patients,and they are mainly represented by worsening of underlying chronic liver disease leading to hepatic decompensation and liver failure with higher *** potential mechanisms used by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)to cause liver damage have been ***-19 primary liver injury is less common than secondary liver *** of the available data demonstrate how liver damage in SARSCo V-2 infection is likely due to systemic inflammation,and it is less likely mediated by a cytopathic effect directed on liver ***,liver alterations could be caused by hypoxic injury and drugs(antibiotics and non-steroidal antiinflammatory drugs,remdesivir,tocilizumab,tofacitinib and dexamethasone).SARS-Co V-2 infection can induce multiple vascular district atherothrombosis by affecting simultaneously cerebral,coronary and peripheral vascular *** in the literature highlight how the virus triggers an exaggerated immune response,which added to the cytopathic effect of the virus can induce endothelial damage and a prothrombotic dysregulation of *** leads to a higher incidence of symptomatic and confirmed venous thrombosis and of pulmonary embolisms,especially in central,lobar or segmental pulmonary arteries,in *** are currently fewer data for arterial thrombosis,while myocardial injury was identified in 7%-17%of patients hospitalized with SARS-Co V-2 infection and 22%-31%in the intensive care unit *** data also revealed a higher occurrence of stroke and more serious forms of peripheral arterial disease in COVID-19 *** dysregulation is observed during the COVID-19 *** platelet count,mildly increased prothrombin time and increased Ddimer are typical laboratory features of patients with severe SAR

关键词： COVID-19 SARS-CoV-2 Liver Coagulation

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Effectiveness of oral probiotics supplementation in the treatment of adult small chalazion

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International Journal of Ophthalmology(English edition) 2022年第1期15卷 40-44页

作者： Mariaelena Filippelli Roberto dell'Omo Angela Amoruso ilaria Paiano Marco Pane Pasquale Napolitano Giuseppe Campagna Silvia Bartollino Ciro Costagliola Department of Medicine and Health Sciences “V.Tiberio”University of MoliseCampobassoMolise 86100Italy Probiotical Research Srl R&D DepartmentNovaraPiemonte 28100Italy Department of Medical-Surgical Sciences and Translational Medicine University of Rome“Sapienza”Rome 00185Italy

AIM:To define the possible beneficial impact of probiotics oral supplementation on patients affected by ***:Prospective comparative pilot study on 20 adults suffering from chalazion randomly divided into two *** first group(n=10)received conservative treatment with lid hygiene,warm compression,and dexamethasone/tobramycin ointment for at least 20 *** second group(n=10),in addition to the conservative treatment,received a mixture of probiotic microorganisms of Streptococcus thermophilus ST10(DSM 25246),Lactococcus lactis LLC02(DSM 29536)and Lactobacillus delbrueckii(DSM 16606)once a day up to 3 *** were classified according to their size into three groups:small(<2 mm),medium(≥2 to<4 mm),or large(≥4 mm).When conservative treatment with and without probiotics supplementation failed to resolve the lesion,invasive methods were used,intralesional steroid injection in medium size chalazion and surgical incision and curettage for the largest ***:Medical treatment with or without probiotics supplementation was effective only on the small size *** was a significant difference in the time taken for complete resolution of small size chalazia between the two groups in favor of the patients receiving probiotics(38.50±9.04 d vs 21.00±7.00 d,P=0.039).Medium and large size chalazia did not respond to medical treatment with or without probiotics supplementation over the follow-up period(3 mo).The treatment did not induce any complications in both groups and no recurrence of chalaziosis was recorded in both ***:The considerable difference in time taken for complete resolution of small chalazia between the two groups in favor of the experimental one confirms the presence of a gut-eye axis.

关键词： microbiome probiotics chalaziosis adults

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The new K_V3.4 inhibitor BDS-I[1–8] as a potential pharmacological opportunity in Alzheimer’s disease therapy

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Neural Regeneration Research 2020年第7期15卷 1255-1256页

作者： ilaria Piccialli Roselia Ciccone Anna Pannaccione Division of Pharmacology Department of NeuroscienceReproductive and Dentistry Sciences School of Medicine Federico II University of Naples

Alzheimer's disease(AD)is the most common neurodegenerative disorder and the first cause of dementia in the elderly,with no treatment able to prevent or to block disease *** is characterized by memory impairment and cognitive dysfunction,followed in the late phases of the disease by severe neurodegeneration and neuronal *** amyloid-β(Aβ)peptide,generated upon the processing of the amyloid precursor protein,is considered the main initiator of AD ***,Aβpeptides,which aggregate and accumulate to form extracellular plaques and intraneuronal deposits.

关键词： inhibitor BDS-I[1-8] BDS Alzheimer

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Advances in Space Medicine Applied to Pandemics on Earth

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Space(Science & Technology) 2021年第1期2021卷 271-273页

作者： ilaria Cinelli Thais Russomano Aerospace Human Factors Association Aerospace Medical AssociationUSA InnovaSpace Ltd&Centre for Human and Applied Physiological Sciences School of Basic&Medical BiosciencesFaculty of Life Sciences and MedicineKing’s College LondonUK

Preparation and planning are critical when facing an epidemic or *** solutions must be incorporated in addition to existing guidelines in the case of a fast-spreading *** in space health have been driven by the need to preserve human health in an austere environment,in which medical assistance or resupply from the ground is not *** paper speculates on the similarities between human spaceflight and epidemics,extended to pandemics,identifying implementable solutions for immediate use by healthcare personnel and healthcare *** believe aerospace medical research can be seen as a resource to improve terrestrial medical care and the management of patients on Earth.

关键词： preserve incorporated addition

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Antagonizing amyloid-β/calcium-sensing receptor signaling in human astrocytes and neurons: a key to halt Alzheimer's disease progression?

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Neural Regeneration Research 2015年第2期10卷 213-218页

作者： ilaria Dal Prà Anna Chiarini Ubaldo Armato Histology & Embryology Section Department of Life & Reproduction Sciences University of Verona Medical School

Astrocytes＇ roles in late-onset Alzheimer＇s disease （LOAD） promotion are important, since they survive soluble or fibrillar amyloid-β peptides （Aβs） neurotoxic effects, undergo alterations of intracellular and intercellular Ca2＋ signaling and gliotransmitters release via the Aβ/a7-nAChR （αT-nicotinic acetylcholine receptor） signaling, and overproduce/oversecrete newly synthesized Aβ42 oligomers, NO, and VEGF-A via the Aβ/CaSR （calcium-sensing receptor） signaling. Recently, it was suggested that the NMDAR （N-methyl-D-aspartate receptor） inhibitor nitromemantine would block the synapse-destroying effects of Aβ/α7-nAChR signaling. Yet, this and the progressive extracellular accrual and spreading of Aβ42 oligomers would be stopped well upstream by NPS 2143, an allosteric CaSR antagonist （calcilytic）.

关键词： Alzheimer's disease amyloid-β astrocytes Ca2+ calcilytic calcium-sensing receptor nitromemantine NPS 2143 aT-nicotinic acetylcholine receptor

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Assessment of lead pollution in topsoils of a southern Italy area: Analysis of urban and peri-urban environment

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Journal of Environmental Sciences 2015年第7期27卷 179-187页

作者： ilaria Guagliardi Domenico Cicchella Rosanna De Rosa Gabriele Buttafuoco Department of Biology Ecology and Earth Sciences University of Calabria Department of Science and Technology University of Sannio National Research Council of Italy Institute for Agricultural and Forest Systems in the Mediterranean (ISAFOM)

Exposure to lead（Pb） may affect adversely human health. Mapping soil Pb contents is essential to obtain a quantitative estimate of potential risk of Pb contamination. The main aim of this paper was to determine the soil Pb concentrations in the urban and peri-urban area of Cosenza-Rende to map their spatial distribution and assess the probability that soil Pb concentration exceeds a critical threshold that might cause concern for human *** were collected at 149 locations from residual and non-residual topsoil in gardens,parks, flower-beds, and agricultural fields. Fine earth fraction of soil samples was analyzed by X-ray Fluorescence spectrometry. Stochastic images generated by the sequential Gaussian simulation were jointly combined to calculate the probability of exceeding the critical threshold that could be used to delineate the potentially risky areas. Results showed areas in which Pb concentration values were higher to the Italian regulatory values. These polluted areas were quite large and likely, they could create a significant health risk for human beings and vegetation in the near future. The results demonstrated that the proposed approach can be used to study soil contamination to produce geochemical maps,and identify hot-spot areas for soil Pb concentration.

关键词： Urban and peri-urban soils Geochemistry Lead Soil pollution Stochastic simulation

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