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Kaempferol and its derivatives:Biological activities and therapeutic potential

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Asian Pacific Journal of Tropical Biomedicine 2023年第10期13卷 411-420页

作者： Shazia Parveen Irshad ul haq Bhat Rajeev Bhat Chemistry Department Faculty of ScienceTaibah UniversityYanbu BranchYanbu-46423Saudi Arabia Department of Chemistry College of ScienceUniversity of BahrainP.O.Box 32038Bahrain ERA-Chair for Food(By-)Products Valorisation Technologies Estonian University of Life SciencesTartu-510014EstoniaEU

Kaempferol,a natural plant-origin flavonoid,exhibits therapeutic anti-inflammatory,antioxidant,anticancer,antidiabetic,and neuroprotective *** acts within several distinct mechanisms like apoptotic induction in cancer cells,enzymatic inhibition,signalling pathway inhibition,and downregulation in cell viability during the G2/M phase of cell *** review summarizes the therapeutic effects of kaempferol against several health *** recent progress on kaempferol obtained from fruits and vegetables as an antioxidant,anti-inflammatory,anticancer,antidiabetic,and neuroprotective agent and its mechanisms of action are also *** addition,kaempferol has been reported to be present in wastes and byproducts from post-fruit and vegetable ***,a paradigm shift towards valorizing fruits and vegetable industrial wastes/byproducts to obtain bioactive kaempferol can support the circular economy pillar for generating wealth from waste and for finding a sustainable alternative source.

关键词： Kaempferol Therapeutic effects Bioactivities Fruits and vegetable wastes Sustainable alternative sources

Electroencephalogram (EEG) Brain Signals to Detect Alcoholism Based on Deep Learning

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Computers, Materials & Continua 2021年第6期67卷 3329-3348页

作者： Emad-ul-haq Qazi Muhammad Hussain Hatim A.AboAlsamh Visual Computing Lab Department of Computer ScienceCollege of Computer and Information SciencesKing Saud UniversityRiyadh11543Saudi Arabia

The detection of alcoholism is of great importance due to its effects on individuals and *** alcoholism detection system(AADS)based on electroencephalogram(EEG)signals is effective,but the design of a robust AADS is a challenging ***’current designs are based on conventional,hand-engineered methods and restricted *** by the excellent deep learning(DL)success in many recognition tasks,we implement an AAD system based on EEG signals using DL.A DL model requires huge number of learnable parameters and also needs a large dataset of EEG signals for training which is not easy to obtain for the AAD *** order to solve this problem,we propose a multi-channel Pyramidal neural convolutional(MP-CNN)network that requires a less number of learnable *** the deep CNN model,we build an AAD system to detect from EEG signal segments whether the subject is alcoholic or *** validate the robustness and effectiveness of proposed AADS using KDD,a benchmark dataset for alcoholism detection *** order to find the brain region that contributes significant role in AAD,we investigated the effects of selected 19 EEG channels(SC-19),those from the whole brain(ALL-61),and 05 brain regions,i.e.,TEMP,OCCIP,CENT,FRONT,and *** results show that SC-19 contributes significant role in AAD with the accuracy of 100%.The comparison reveals that the state-of-the-art systems are outperformed by the *** proposed AADS will be useful in medical diagnosis research and health care systems.

关键词： Electroencephalogram convolutional neural network deep learning alcoholism

Significantly enhanced flashover voltage of epoxy in vacuum by graded surface roughness modification

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High Voltage 2023年第5期8卷 997-1010页

作者： Inzamam ul haq Feipeng Wang Shakeel Akram Muneeb Ahmed Muhammad Tariq Nazir State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing UniversityChongqingChina College of Electrical Engineering and Control Science Nanjing Tech UniversityNanjingChina State Key Laboratory of Electrical Insulation and Power Equipment Xi'an Jiaotong UniversityXi'anChina School of Engineering RMIT UniversityMelbourneVictoriaAustralia

The flashover strength of epoxy(EP)insulations in the High voltage direct current applications of future energy grids can be improved by tailoring their surface *** work aims to improve the DC surface flashover characteristics of EP after being treated with sandpaper of different *** with virgin EP and homogenously modified EP considering varying surface roughness(R_(a)=0.54,3.16,5.24,and 8.35μm)are *** experimental characterisations,such as water contact angle,surface intrinsic conductivity,surface voltages,flashover strength,and trap distributions are conducted and evaluated to analyse the difference between virgin and treated ***,based on the obtained experimental results of homogenously treated EP and theoretical analysis,the concept of surface functionally graded materials(SFGMs)is put *** flashover voltages of homogenously treated EP are augmented significantly compared to virgin EP regardless of the voltage polarity and enhanced by enhancing the surface *** sample T_(Model‐C) with SFGM design shows a 45.02%and 43.75%improvement in the negative and positive flashover voltages than that of the virgin *** the end,COMSOL simulations are conducted to justify the experimental findings and to analyse the difference between virgin and modified samples in terms of electric field distribution.

关键词： flash graded roughness

Growth,yield and water productivity of dry direct seeded rice and transplanted aromatic rice under different irrigation management regimes

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Journal of Integrative Agriculture 2020年第11期19卷 2656-2673页

作者： Muhammad Ishfaq Nadeem Akbar Shakeel Ahmed Anjum Muhammad Anwar-ul-haq Department of Agronomy University of AgricultureFaisalabad 38040Pakistan Department of Plant Science University of CaliforniaCalifornia 95616-8780USA Institute of Soil and Environmental Sciences University of AgricultureFaisalabad 38040Pakistan

Sustainability of traditionally cultivated rice in the rice-wheat cropping zone(RWCZ)of Pakistan is dwindling due to the high cost of production,declining water resources and escalating labour ***,farmers and researchers are compelled to find promising alternatives to traditional transplanted rice(TPR).A field study was conducted in Punjab,Pakistan,in 2017 and 2018 to explore the trade-offs between water saving and paddy yield,water productivity and economics of two aromatic rice varieties under dry direct seeded rice(DDSR)and *** experiment was comprised of three irrigation regimes on the basis of soil moisture tension(SMT)viz.,continuous flooded(>–10 kPa SMT),alternate wetting and drying(AWD)(–20 kPa SMT)and aerobic rice(–40 kPa SMT),maintained under TPR and DDSR *** aromatic rice verities:Basmati-515 and Chenab Basmati-2016 were used during both years of *** both years,DDSR produced higher yields(13–18%)and reduced the total water inputs(8–12%)in comparison to *** comparison to traditional continuous flooded(CF),AWD under DDSR reduced total water input by 27–29%and improved the leaf area index(LAI),tillering,yield(7–9%),and water productivity(44–50%).The performance of AWD with regard to water savings and increased productivity was much higher in DDSR system as compared to AWD in TPR *** of DDSR with aerobic irrigation improved water savings(49–55%)and water productivity(22–30%)at the expense of paddy yield reduction(36–39%)and spikelet *** regard to variety,the highest paddy yield(6.6 and 6.7 t ha–1)was recorded in DDSR using Chenab Basmati-2016 under AWD irrigation threshold that attributed to high tiller density and *** economic analysis showed DDSR as more beneficial rice establishment method than TPR with a high benefit-cost ratio(BCR)when the crop was irrigated with AWD irrigation *** results highlighted that with the use of short duration varieties,DDSR cultivation in conjunction wit

关键词： rice establishment aerobic alternate wetting and drying water input tillering yield

Biodegradation of Leather Waste by Enzymatic Treatment

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过程工程学报 2006年第3期6卷 462-465页

作者： Muhammad Nauman Aftab Abdul Hameed Ikram-ul-haq 陈润生 Dept. Biol. Sci. Quaid-i-Azam Univ.IslamabadPakistan Bioinformatics LabInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China Graduate University of Chinese Academy of SciencesBeijing 100049China Dept. Biol. Sci. Quaid-i-Azam Univ.IslamabadPakistan Dept. Botany Government College Univ.LahorePakistan Bioinformatics Lab Institute of BiophysicsChinese Academy of SciencesBeijing 100101China

The treatment of shavings,trimmings and splits of leather waste from tanneries has a potential to generate value-added products. In this study enzymatic treatment of leather waste was performed. This method utilizes alkaline protease produced by Bacillus subtilis in our laboratory by submerged fermentation. Optimum conditions of pH,time duration,temperature and concentration of enzyme were determined for maximum degradation of leather waste. The amount of degradation was measured by the release of amino acid hydroxyproline. Amino acid composition in the hydrolysate obtained by the enzyme hydrolysis was determined. This relative simple biotreatment of leather waste may provide a practical and economical solution.

关键词： leather waste biodegadation Bacillus subtilis alkaline protease

Radiation efects on MHD stagnation point flow of nano fluid towards a stretching surface with convective boundary condition

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Chinese Journal of Aeronautics 2013年第6期26卷 1389-1397页

作者： Noreen Sher Akbar S.Nadeem Rizwan ul haq Z.H.Khan DBS&H CEMENational University of Sciences and TechnologyIslamabad 44000Pakistan Department of Mathematics Quaid-i-Azam UniversityIslamabad 44000Pakistan School of Mathematical Sciences Peking University

The aim of the present paper is to study the numerical solutions of the steady MHD two dimensional stagnation point flow of an incompressible nano fluid towards a stretching *** effects of radiation and convective boundary condition are also taken into *** model used for the nanofluid incorporates the effects of Brownian motion and *** resulting nonlinear momentum,energy and nano particle equations are simplifed using similarity *** solutions have been obtained for the velocity,temperature and nanoparticle fraction *** influence of physical parameters on the velocity,temperature,nanoparticle fraction,rates of heat transfer and nanoparticle fraction are shown graphically.

关键词： Convective boundary condition Nanoparticles Numerical solutions Radiation effects Stagnation point Stretching surface

Certificate revocation in vehicular ad hoc networks techniques and protocols: a survey

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Science China(Information Sciences) 2017年第10期60卷 7-24页

作者： Taimur KHAN Naveed AHMAD Yue CAO Syed Asim JALAL Muhammad ASIF Sana ul haq Haitham CRUICHSHANK Department of Computer Sciences University of Peshawar Department of Computer and Information Sciences Northumbria University Institute of Communication Systems University of Surrey

Vehicular Ad hoc Networks(VANETs) are special kind of Mobile Ad hoc Networks(MANETs),where vehicles communicate with each other in ad hoc formation. VANETs consist of Vehicles and Road Side Units(RSUs) that assist in the network management. Vehicles communicate with each other and RSUs, with the aim to provide infotainment and safety services on road. Security is an important consideration in VANETs as safety of humans(passengers) is an important issue. Vehicular Public Key Infrastructure(VPKI) is an adapted form of Public Key Infrastructure(PKI) used to achieve the key management and security services in *** generation and revocation is one of the primary functions of VPKI. Certificate revocation is used for revoking the malicious nodes and terminate their access rights to the network. In this paper we classify revocation schemes in a novel way into centralized and decentralized manners. This paper covers a survey of different certificate revocation schemes, and provides an overview of the research in the area of certificate revocation in VANETs.

关键词： certificate revocation list VANETs Intelligent Transportation System(ITS) Public Key Infrastructure(PKI) Vehicular Public Key Infrastructure(VPKI)

Structural and optoelectronic properties of CsLnZnTe_(3)(Ln=La,Pr,Nd and Sm)

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Journal of Rare Earths 2023年第3期41卷 388-396,I0003页

作者： Imad Khan Ihsan ullah Izaz ul haq Akbar Ali A.Dahshan Zahid Ali Iftikhar Ahmad Center for Computational Materials Science Department of PhysicsUniversity of MalakandChakdaraPakistan Department of Physics Faculty of ScienceKing Khalid UniversityP.O.Box 9004AbhaSaudi Arabia Department of Physics Faculty of SciencePort Said UniversityPort SaidEgypt Gomal University Dera Ismail KhanPakistan

Zinc telluride is a versatile wide band gap semiconductor used in many *** it has certain limitations like large dimensions and large band *** alkali metal to its bulk lattice(3D)can reduce its dimensions and lanthanide can produce a red shift in the energy gap by converting it into quaternary *** alkali and lanthanide incorporated quaternary zinc tellurides CsLnZnTe_(3)(Ln=La,Pr,Nd and Sm)form layered crystal structure in which_(∞)^(2)[LnZnTe_(3)]-layers are separated by Cs+*** famous lanthanide contraction is experimental both from lattice constants and bond *** calculated band gaps are 2.26,2.28,2.12,2.05 eV for CsLaZnTe_(3),CsPrZnTe_(3),CsNdZnTe_(3) and CsSmZnTe_(3),*** compounds show direct band gap *** energy band gaps of these compounds have not been evaluated yet both experimentally and *** loss functions,refractive index and dielectric functions were also calculated to explore the potential applications of CsLnZnTe_(3) in optoelectronic devices.

关键词： Chalcogenides Optical materials Electronic structure Dimensions reduction Ab-initio calculations Rare earths

Comprehensive screening and selection of okra (Abelmoschus esculentus) germplasm for salinity tolerance at the seedling stage and during plant ontogeny

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第7期13卷 533-544页

作者： Ikram-ul-haq Asif Ali KHAN Iqrar Ahmad KHAN Muhammad Abubakkar AZMAT Department of Plant Breeding and Genetics University of AgricultureFaisalabadPakistan Institute of Horticultural Sciences University of AgricultureFaisalabadPakistan

The okra germplasm was screened for salinity tolerance at the seedling stage and during plant ontogeny. Substantial variation existed in okra for salinity tolerance at the seedling stage. An 80 mmol/L NaCI concentration was suitable for discriminating tolerant and non-tolerant okra genotypes. The pooled ranking of the genotypes, based on individual rankings for each trait （root and shoot length, germination percentage, and relative Na^＋ and K%＋） in individual NaCI concentrations, was effective for selecting tolerant genotypes. Genotypes selected at the seedling stage maintained their tolerance to NaCI during plant ontogeny, suggesting that screening of the germplasm entries and advanced breeding materials for salt tolerance at the seedling stage is effective. Among 39 okra genotypes, five were identified as the most tolerant genotypes and showed potential for use in breeding programs that focus on the development of salt-tolerant, high-yield okra cultivars.

关键词： Salinity tolerance Okra Growth stage Genetic variation Mechanism Potassium to sodium ion ratio (K^+/Na^+)