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High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic

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Infectious Diseases of Poverty 2019年第6期8卷 39-50页

作者： sulaiman S.ibrahim Amen N.Fadel Magellan Tchouakui Ebai Terence Murielle J.Wondji Micareme Tchoupo Clement Kerah-Hinzoumbe Samuel Wanji Charles S.Wondji Vector Biology Department Liverpool School of Tropical Medicine(LSTM)Liverpool L35 QAUK Department of Biochemistry Bayero UniversityKano PMB 3011Nigeria Centre for Research in Infectious Diseases(CRID) LSTM Research UnitP.O.Box 13591YaoundeCameroon Department of Microbiology and Parasitology University of BueaP.O.Box 63BueaCameroon National Malaria Control Program P.O.Box 2030N'djamenaChad

Background:The Sahel region of Chad Republic is a prime candidate for malaria *** facilitate preelimination efforts in this region,two populations o f A nopheles coluzzii from Central Chad Republic were characterized,their insecticide resistance profile and the possible molecular mechanisms driving the resistance in the field ***:Bloodfed female Anopheles gom biae *** indoor,were collected at N'djamena and Massakory,Chad in 2018 and characterized for species composition,and infection rate was determined using the TaqMan *** to various insecticides was assessed using WHO tube *** bioassays were conducted using various long-lasting insecticidal nets(LLINs).Results were analysed using Chi Square *** resistance(kdr)and ace-1 markers were investigated by TaqMan ***:Anopheles coluzzi was the major vector found in N’djamena(100%)and Massakory(〜94%).N〇Plasm odium was found in 147 bloodfed F0 ***(82 from N'djamena and 65 from Massakory).High intensity pyrethroid resistance was observed with mortalities of<2%for permethrin,deltamethrin and etofenprox,and with<50%and<60%dead following exposure to 10x diagnostic doses of deltamethrin and permethrin,*** both sites,<10%mortalities were observed with *** bioassays with piperonylbutoxide significantly recovered pyrethroid susceptibility in Massakory populations,implicating CYP450s(mortality=13.6%for permethrin,X^2=22.8,df=1,P=0.0006;mortality=13.0%for deltamethrin,x2:8.8,df=1,P<0.00031).Cone-bioassays established complete loss of efficacy of the pyrethroid-based LLINs;and a 100%recovery of susceptibility following exposure to the roof of PermaNet®3.0/containing *** populations were susceptible to malathion,but high bendiocarb resistance was observed in Massakory *** absence o f a ce-1 mutation points to the role of metabolic resistance in the bendiocarb *** 1014F and

关键词： Anopheles coluzzii Malaria Sahel Chad Insecticide Resistance Metabolic Kdr

Epispadias in a Child with Intact Prepuce: A Rare Congenital Abnormality

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Open Journal of Urology 2016年第3期6卷 19-22页

作者： Abubakar Maina Waziri Babagana Mustapha Abubakar Sani Adamu ibrahim Eneye sulaiman Mohammed Gashua Department of Surgery Dr. Hassan’s Clinic and Diagnostic Center Abuja Nigeria Department of Surgery Federal Medical Centre Nguru Nigeria Department of Surgery Federal University Teaching Hospital Gombe Nigeria Department of Surgery Aminu Kano Teaching Hospital/Bayero University Kano Nigeria

Epispadias is a rare genitourinary malformation, more so is epispadias with intact prepuce. Incidence of epispadias with intact prepuce is not known however, there are few case reports and a case series. We present a 5-year-old boy brought to our facility by his parent for circumcision. Further evaluation revealed a short penis with broad base and intact prepuce. The preputial slit was dorsally oriented. On retracting the prepuce, there was corona epispadias with wide and healthy urethral plate. No meatal stenosis or chordee noticed. Other findings were normal. He had epispadias repair. The postoperative period was uneventful. Three months after operation, the prepuce was easily retractable over the penis and the penis was cosmetically acceptable.

关键词： Epispadias Intact Prepuce Epispadias Repair Congenital Genito-Urinary Abnormality

Classifying rockburst with confidence:A novel conformal prediction approach

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International Journal of Mining Science and Technology 2024年第1期34卷 51-64页

作者： Bemah ibrahim Isaac Ahenkorah University of South Australia UniSA STEMSA 5000Australia

The scientific community recognizes the seriousness of rockbursts and the need for effective mitigation *** literature reports various successful applications of machine learning(ML)models for rockburst assessment;however,a significant question remains unanswered:How reliable are these models,and at what confidence level are classifications made?Typically,ML models output single rockburst grade even in the face of intricate and out-of-distribution samples,without any associated confidence *** the susceptibility of ML models to errors,it becomes imperative to quantify their uncertainty to prevent consequential *** address this issue,we propose a conformal prediction(CP)framework built on traditional ML models(extreme gradient boosting and random forest)to generate valid classifications of rockburst while producing a measure of confidence for its *** proposed framework guarantees marginal coverage and,in most cases,conditional coverage on the test *** CP was evaluated on a rockburst case in the Sanshandao Gold Mine in China,where it achieved high coverage and efficiency at applicable confidence ***,the CP identified several“confident”classifications from the traditional ML model as unreliable,necessitating expert verification for informed *** proposed framework improves the reliability and accuracy of rockburst assessments,with the potential to bolster user confidence.

关键词： Rockburst Machine learning Uncertainty quantification Conformal prediction

Renewable Energy Transition: A Panacea to the Ravaging Effects of Climate Change in Nigeria

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Journal of Geoscience and Environment Protection 2021年第12期9卷 151-167页

作者： Usman Bello Livingstone Udofia Olayinka A. Ibitowa Auwal M. Abdullahi ibrahim sulaiman Khuzaifah M. Yahuza Department of Chemistry Abubakar Tafawa Balewa University Bauchi Nigeria Department of Chemical Engineering Universiti Teknologi PETRONAS Malaysia Institute of Chemistry Otto Von Guericke Universit&#228 t Magdeburg Germany Institute of Chemistry Carl Von Ossietzky Universit&#228 t Oldenburg Germany Department of Chemistry Bayero University Kano Nigeria Department of History Bayero University Kano Nigeria

Environmental issues linked to climate change and global warming have been at the centre stage of discussion all over the world, considering their magnitude and the broader scope of consequences. These catastrophic effects of greenhouse gases (GHG) such as CO2, CO, water vapour, nitrous oxides, ozone, coupled with other artificially induced chemicals like CFCs have shifted weather patterns across the globe, thereby threatening the environment unpleasantly. However, the effects of climate changes are more pronounced in Nigeria, due to an unprecedented utilization of fossil-based fuels as the main energy source for electricity, transportation, industrial, agricultural, and domestic purposes. As a result, air pollution and land spills by oil led to the destruction of agricultural land and increasing heatwaves were left behind. Consequently, these impacted negatively on the ecosystem by intimidating the environment, counteracting biodiversity, decelerating economy and provoking human comfort, while simultaneously antagonizing socio-economic growth and sustainable developments. Thus, an urgent need for the Nigerian government to redirect from fossil fuels to renewables and intensify the campaign for afforestation to support green conservation of biodiversity. These are considered plausible measures for remediating the lingering energy failure and ravaging effects

关键词： Renewable Energy Environment Climate Change Global Warming and Sus-tainable Developments

New insights into astrocyte diversity from the lens of transcriptional regulation and their implications for neurodegenerative disease treatments

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Neural Regeneration Research 2024年第11期19卷 2335-2336页

作者： ibrahim Olabayode Saliu Guoyan Zhao Department of Genetics Washington University School of MedicineSt.LouisMOUSA Department of Neurology Department of Pathology and ImmunologyWashington University School of MedicineSt.LouisMOUSA

Astrocytes are a major glial cell type in the central nervous system,and they provide trophic and metabolic support to *** addition to these roles,they play crucial roles in modulating synaptic functions,development,and pruning(Brandebura et al.,2023).Astrocytes become reactive(activated)by undergoing morphological,molecular,and functional alterations in response to neuropathology such as in injuries and neurodegenerative diseases(NDs)(Escartin et al.,2021).

关键词： degenerative injuries

Enteric neuropathy in diabetes:Implications for gastrointestinal function

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World Journal of Gastroenterology 2024年第22期30卷 2852-2865页

作者： Mona Mohamed ibrahim Abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes,commonly known for its metabolic effects,also critically affects the enteric nervous system(ENS),which is essential in regulating gastrointestinal(GI)motility,secretion,and *** development of diabetes-induced enteric neuropathy can lead to various GI dysfunctions,such as gastroparesis and irregular bowel habits,primarily due to disruptions in the function of neuronal and glial cells within the ENS,as well as oxidative stress and *** editorial explores the pathophysiological mechanisms underlying the development of enteric neuropathy in diabetic ***,it discusses the latest advances in diagnostic approaches,emphasizing the need for early detection and intervention to mitigate GI complications in diabetic *** editorial also reviews current and emerging therapeutic strategies,focusing on pharmacological treatments,dietary management,and potential neuromodulatory ***,this editorial highlights the necessity of a multidisciplinary approach in managing enteric neuropathy in diabetes,aiming to enhance patient quality of life and address a frequently overlooked complication of this widespread disease.

关键词： Diabetic neuropathy Gastrointestinal Insulin resistance Diabetes Enteric nervous system Enteric neuropathy

Relational Turkish Text Classification Using Distant Supervised Entities and Relations

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Computers, Materials & Continua 2024年第5期79卷 2209-2228页

作者： Halil ibrahim Okur Kadir Tohma Ahmet Sertbas Department of Computer Engineering Faculty of Engineering and Natural SciencesIskenderun Technical UniversityHatay31200Turkey Department of Computer Engineering Faculty of EngineeringIstanbul University-CerrahpasaIstanbul34310Turkey

Text classification,by automatically categorizing texts,is one of the foundational elements of natural language processing *** study investigates how text classification performance can be improved through the integration of entity-relation information obtained from the Wikidata(Wikipedia database)database and BERTbased pre-trained Named Entity Recognition(NER)*** on a significant challenge in the field of natural language processing(NLP),the research evaluates the potential of using entity and relational information to extract deeper meaning from *** adopted methodology encompasses a comprehensive approach that includes text preprocessing,entity detection,and the integration of relational *** conducted on text datasets in both Turkish and English assess the performance of various classification algorithms,such as Support Vector Machine,Logistic Regression,Deep Neural Network,and Convolutional Neural *** results indicate that the integration of entity-relation information can significantly enhance algorithmperformance in text classification tasks and offer new perspectives for information extraction and semantic analysis in NLP *** of this work include the utilization of distant supervised entity-relation information in Turkish text classification,the development of a Turkish relational text classification approach,and the creation of a relational *** demonstrating potential performance improvements through the integration of distant supervised entity-relation information into Turkish text classification,this research aims to support the effectiveness of text-based artificial intelligence(AI)***,it makes significant contributions to the development ofmultilingual text classification systems by adding deeper meaning to text content,thereby providing a valuable addition to current NLP studies and setting an important reference point for future research.

关键词： Text classification relation extraction NER distant supervision deep learning machine learning

Outcome of percutaneous reconstruction of chronic lateral collateral ligament rupture

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Chinese Journal of Traumatology 2024年第1期27卷 58-62页

作者： Soliudeen Adebayo Arojuraye ibrahim Abolaji Alabi ibrahim Usman Mustapha Department of Orthopaedics National Orthopaedic Hospital Dala-KanoNigeria Department of Surgery Bayero University KanoNigeria

Purpose:Many techniques have been described for the reconstruction of chronic lateral collateral ligament(LCL)rupture with different autograft *** advantages of percutaneous LCL reconstruction include small incisions,minimal soft tissue disruption,less postoperative pain,and speedy rehabilitation and *** aim of this study was to report the functional outcome of percutaneous LCL reconstruction and overall patient satisfaction in ***:This prospective and interventional study involving 51 patients with chronic LCL rupture who had percutaneous LCL reconstruction using peroneus longus autograft was conducted between January 2021 and December 2022 in National Orthopaedic Hospital,Dala-Kano,*** inclusion criteria were patients between the ages of 18 and 45 years with chronic isolated LCL and not more than 1 injury of knee *** criteria were active infection,and multi-ligament knee injury requiring 2-staged *** knee functions were assessed preoperatively,3 months,6 months,and 12 months postoperatively using the Lysholm scoring *** satisfaction with the outcome of the treatment was assessed using a 5-point Likert *** information was recorded into Microsoft Excel sheet and data was analyzed using SPSS version 23.0 for *** paired samples t-test was used to compare the clinical outcomes as continuous *** significance was considered at p<***:The mean age of the patients was(30.10±5.90)*** median time from injury to surgery was 7 months(ranging from 3 to 28 months).The mean follow-up period was(14.07±3.13)*** mean preoperative and 1-year postoperative Lysholm scores were 44.33±12.97 and 97.96±1.23,***:Percutaneous LCL reconstruction using peroneus longus autograft significantly improves patient knee function and results in excellent patient satisfaction。

关键词： rupture ligament percutaneous

(Sm/Eu/Tm)^(3+) doped tantalum semiconductor system for photovoltaic and electrochemical functionality amplification

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Journal of Rare Earths 2024年第8期42卷 1586-1594,I0007页

作者： Shaan Bibi Jaffri Khuram Shahzad Ahmad Isaac Abrahams ibrahim A.A Materials and Environmental Chemistry Lab Lab-E21Department of Environmental SciencesFatima Jinnah Women UniversityRawalpindiPakistan School of Physical and Chemical Sciences Queen Mary University of LondonLondonUnited Kingdom Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box 2455Riyadh11451Saudi Arabia

This work reports the synthesis,characterization,and energy focused applications of the novel lanthanides co-doped tantalum pentoxide hetero-system(Sm^(3+)-Eu^(3+)-Tm^(3+):Ta_(2)O_(5)).Ln^(3+)-doped Ta_(2)O_(5) express excellent opto-electronic features reflected by the narrow band gap energy of 3.87 *** vibrations confirm the presence of Ta-O-Ta and Ta-O *** synthesized system possesses orthorhombic geometry with 59.46 nm particle *** the smoother and compact morphology,the synthesized material succeeds in augmenting the performance of different systems aimed at energy *** ambient perovskite solar cell device fabricated with the Ln^(3+)-doped Ta_(2)O_(5) as an electron transport layer excels in achieving an efficiency and fill factor of 14.17% and 76% under artificial *** device was marked by the negligible hysteresis behavior showing profound photovoltaic *** electrochemical activity of the Ln^(3+)-doped Ta_(2)O_(5) decorated electrode was evaluated for electrical charge storage potential with pseudocapacitive behavior,With the highest specific capacitance of 355.39 F/g and quicker ionic diffusion rate,the designed electrode excels conventionally used ***-catalysis of water with Ln^(3+)-doped Ta_(2)O_(5) material indicates its capacity for H_(2) production with the lowest overpotential and Tafel slope values of 148 and 121.2 mV/dec,while the O_(2) generation is comparatively *** the stable electrochemical output,this rare earth modified material has the potential to replace conventionally used environmentally perilous and costly materials.

关键词： Lanthanide doping Rare earth materials Perovskite solar cells Supercapacitors Water splitting