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Asian Pacific Journal of Tropical Biomedicine 2015年第4期5卷 300-309页

作者： Hassan el-Sayyed Gamal Badawy Sobhy Hassab elnabi ibrahim el-elaimy Eman Al Shehari Department of Zoology Faculty of Science Mansoura University Department of Zoology Faculty of Science Menoufiya University

Objective: To investigate the possible ameliorative effect of crude water extract of Morus alba(M. alba) leaves on retinopathy of rat pups maternally subjected to diabetes and/or Al ***: Both control and experimental groups were subjected to certain integrated approaches, namely, biochemical assessments, light microscopic investigation, transmission electron microscopic investigation, single cell gel electrophoresis(comet assay) and determination of DNA ***: The retina of pups of diabetic and/or Al-intoxicated mothers exhibited abnormal alterations in retinal cell layers including retinal pigmented epithelium, photoreceptor inner segment and ganglion cells. Increased incidence of DNA fragmentation and apoptosis were evident in pups of diabetic and/or Al-intoxicated mothers. However, retina of pups maternally received M. alba extract plus diabetes or Al-intoxicated alone or in combination showed marked amelioration. Less degree of ameliorations was seen in retina of pups maternally subjected to combined treatment. Furthermore, application of crude water extract of *** resulted in amelioration of the alterations of maternal serum glucose as well as Al ***: Based on the results of the present study, M. alba extract is effective against experimentally diabetic and Al-induced developmental retinopathy.

关键词： Morus alba Retinopathy Aluminum Diabetes TEM Comet assay

Gastroesophageal reflux after per-oral endoscopic myotomy:Management literature

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World Journal of Gastroenterology 2024年第23期30卷 2947-2953页

作者： Ahmed Tawheed ibrahim Halil Bahcecioglu Mehmet Yalniz Mohamed el-Kassas Department of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt Department of Gastroenterology Faculty of MedicineFirat UniversityElazig 23119Türkiye Liver Disease Research Center College of MedicineKing Saud UniversityRiyadh 7805Saudi Arabia

In this editorial,we respond to a review article by Nabi et al,in which the authors discussed gastroesophageal reflux(GER)following peroral endoscopic myotomy(POEM).POEM is presently the primary therapeutic option for achalasia,which is both safe and effective.A few adverse effects were documented after POEM,including *** diagnostic criteria were not clear enough because approximately 60%of patients have a long acid exposure time,while only 10%experience reflux *** predictors of high disease incidence have been identified,including old age,female sex,obesity,and a baseline lower esophageal sphincter pressure of less than 45 *** technical steps during the procedure,such as a lengthy or full-thickness myotomy,may further enhance the *** pump inhibitors are currently the first line of *** voices are increasingly advocating for the routine combining of POEM with an endoscopic fundoplication method,such as peroral endoscopic fundoplication or transoral incisionless ***,more research is necessary to determine the safety and effectiveness of these procedures in the long term for patients who have undergone them.

关键词： Achalasia Per-oral endoscopic myotomy Gastroesophageal reflux disease Transoral incisionless fundoplication Peroral endoscopic fundoplication

Urban electric Vehicle Charging Station Placement Optimization with Graylag Goose Optimization Voting Classifier

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Computers, Materials & Continua 2024年第7期80卷 1163-1177页

作者： Amel Ali Alhussan Doaa Sami Khafaga el-Sayed M.el-kenawy Marwa M.Eid Abdelhameed ibrahim Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Communications and electronics Delta Higher Institute for Engineering and TechnologyMansoura35511Egypt Faculty of Artificial Intelligence Delta University for Science and TechnologyMansoura35712Egypt Computer Engineering and Control Systems Department Faculty of EngineeringMansoura UniversityMansoura35516Egypt

To reduce the negative effects that conventional modes of transportation have on the environment,researchers are working to increase the use of electric *** demand for environmentally friendly transportation may be hampered by obstacles such as a restricted range and extended rates of *** establishment of urban charging infrastructure that includes both fast and ultra-fast terminals is essential to address this ***,the powering of these terminals presents challenges because of the high energy requirements,whichmay influence the quality of *** the maximum hourly capacity of each station based on its geographic location is necessary to arrive at an accurate estimation of the resources required for charging *** is vital to do an analysis of specific regional traffic patterns,such as road networks,route details,junction density,and economic zones,rather than making arbitrary conclusions about traffic *** vehicle traffic is simulated using this data and other variables,it is possible to detect limits in the design of the current traffic engineering ***,the binary graylag goose optimization(bGGO)algorithm is utilized for the purpose of feature ***,the graylag goose optimization(GGO)algorithm is utilized as a voting classifier as a decision algorithm to allocate demand to charging stations while taking into consideration the cost variable of traffic *** on the results of the analysis of variance(ANOVA),a comprehensive summary of the components that contribute to the observed variability in the dataset is *** results of the Wilcoxon Signed Rank Test compare the actual median accuracy values of several different algorithms,such as the voting GGO algorithm,the voting grey wolf optimization algorithm(GWO),the voting whale optimization algorithm(WOA),the voting particle swarm optimization(PSO),the voting firefly algorithm(FA),and the voting genetic algori

关键词： electric vehicle graylag goose optimization metaheuristics optimization machine learning

Classifying rockburst with confidence:A novel conformal prediction approach

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International Journal of Mining Science and Technology 2024年第1期34卷 51-64页

作者： Bemah ibrahim Isaac Ahenkorah University of South Australia UniSA STEMSA 5000Australia

The scientific community recognizes the seriousness of rockbursts and the need for effective mitigation *** literature reports various successful applications of machine learning(ML)models for rockburst assessment;however,a significant question remains unanswered:How reliable are these models,and at what confidence level are classifications made?Typically,ML models output single rockburst grade even in the face of intricate and out-of-distribution samples,without any associated confidence *** the susceptibility of ML models to errors,it becomes imperative to quantify their uncertainty to prevent consequential *** address this issue,we propose a conformal prediction(CP)framework built on traditional ML models(extreme gradient boosting and random forest)to generate valid classifications of rockburst while producing a measure of confidence for its *** proposed framework guarantees marginal coverage and,in most cases,conditional coverage on the test *** CP was evaluated on a rockburst case in the Sanshandao Gold Mine in China,where it achieved high coverage and efficiency at applicable confidence ***,the CP identified several“confident”classifications from the traditional ML model as unreliable,necessitating expert verification for informed *** proposed framework improves the reliability and accuracy of rockburst assessments,with the potential to bolster user confidence.

关键词： Rockburst Machine learning Uncertainty quantification Conformal prediction

Microbial,immune and antioxidant responses of Nile tilapia with dietary nano-curcumin supplements under chronic low temperatures

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Aquaculture and Fisheries 2024年第1期9卷 57-65页

作者： Mohammed F.el Basuini Mohamed A.A.Zaki Abdelaziz M.el-Hais Mohamed G.elhanafy Emad H.el-Bilawy Amr I.Zaineldin Mohamed F.A.Abdel-Aziz ibrahim A.Abouelsaad ibrahim Tel-Ratel Kumbukani Mzengereza Ronick S.Shadrack Islam I.Teiba Faculty of Agriculture Tanta UniversityTanta31527Egypt King Salman International University South Sinai46618Egypt Faculty of Agriculture Alexandria UniversityAlexandria21526Egypt Animal Health Research Institute(AHRI-DOKI) Agriculture Research CenterGiza12619Egypt Fish Rearing Lab. Aquaculture DivisionNational Institute of Oceanography and FisheriesAlexandria21556Egypt Horticulture Department Faculty of AgricultureDamanhour UniversityDamanhur22511Egypt Department of Poultry Production Faculty of AgricultureDamietta UniversityDamietta34517Egypt Laboratory of Aquatic Animal Nutrition Faculty of FisheriesKagoshima UniversityKagoshima890-0065Japan Department of Aquatic and Fisheries Science Mzuzu UniversityMzuzuPrivate Bag 201Malawi Faculty of Aquaculture and Marine Fisheries Arish UniversityArish45516Egypt

A 56-day feeding period was performed to investigate the possible impacts of dietary nano curcumin(0,50,100,150,and 200 ppm)on the growth,nutrient utilization,non-specific immune parameters,antioxidants in Nile tilapia under chronic low temperature(21.02±0.11◦C).Fishes(n=225;Initial weight=4.39±0.08 g/fish)were randomly stocked at 15 fish/tank for five experimental groups in *** low-temperature circumstances,dietary curcumin in nano form showed no notable alteration in growth variable,nutrient efficiency,digestive enzymes efficiency,biometric indices,survival rates,and hematological ***,the serum of fishes with nano curcumin diets under low-temperature stress displayed higher total protein as well as lower glucose,cortisol,and total cholesterol compared with the control ***,fish fed nano curcumin diets displayed higher lysozyme and bactericidal activities compared to the control group and the best performance was found at dietary nano curcumin level of≥100 ***,groups fed the basal diet demonstrated the poorest antioxidant capacity,and the best superoxide dismutase(SOD)and glutathione peroxidase(GPx)existed in fish with nano curcumin diets while the best catalase(CAT)efficiency occurred at higher nano curcumin levels≥100 *** addition,higher counts of intestinal microbiota in terms of total bacterial count(TBC),total yeast and molds count(TYMC),and coliform were noticed in fish consumed the basal diet compared to groups fed on nano curcumin *** conclusion,incorporating nano curcumin at a level of≥100 mg/kg diet(particularly at 150 mg/kg)improved a non-specific immune response,antioxidant,and healthier gastrointestinal microbiota in Nile tilapia under chronic low-temperature stress.

关键词： Nano curcumin Gastrointestinal microbiota Antioxidants Non-specific immune responses Temperature stress

A numerical investigation into the effect of altering compression ratio, injection timing, and injection duration on the performance of a diesel engine fuelled with diesel-biodiesel-butanol blend

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Clean Energy 2024年第5期8卷 73-96页

作者： Abdulkarim Youssef Amr ibrahim Mechanical Engineering Department Beirut Arab University115020 BeirutLebanon Mechanical Engineering Department Alexandria UniversityAlex 21544Egypt

Using renewable fuels for diesel engines can reduce both air pollution and dependence on fossil fuels.A computer simulation was constructed to predict the performance,combustion characteristics,and NOx emissions of a diesel engine fuelled with diesel-biodiesel-butanol *** simulation was validated by comparing the modelling results against experimental data and a good agreement between the results was *** fuels used for the validation were diesel(B0),biodiesel(B100),diesel-biodiesel blend(B50),and two diesel-biodiesel-butanol blends with 45%diesel-45%biodiesel-10%butanol(Bu10)and 40%diesel-40%biodiesel-20%butanol(Bu20)by *** results showed that the addition of butanol reduced NOx emissions but deteriorated the engine *** aim of the current work was the numerical optimization of the different parameters to enhance the engine performance while using butanol to decrease NOx *** engine compression ratio(CR)varied from 14 to 24,in increments of *** injection timing(IT)was reduced from 30°before top dead centre(bTDC)to 5°bTDC in increments of 5°.Also,the fuel injection duration(IDur)was extended from 20°to 50°in increments of 10°.Results showed that the increase in the CR improved engine performance for the two investigated fuels,Bu10 and *** maximum engine brake power(BP),thermal efficiency(BTE),and minimum brake-specific fuel consumption(BSFC)of 1.46 kW,32.3%,and 0.273 kg/kWh respectively,were obtained when the Bu10 fuel was injected under the optimum conditions of 24 CR,15°bTDC IT,and 40°*** these optimum conditions,the BP,BTE,and BSFC improved by 3%-3.5%for Bu10 and Bu20 fuel blends compared with the base engine conditions of a CR of 22,30°IDur,and 10°bTDC *** heat release rate during the premixed phase increased when the IT was advanced,while the mixing-controlled combustion phase was enhanced when the IT was *** emissions increased with increasing CR,while both an increase in IDur at con

关键词： compression ratio injection timing injection duration butanol biodiesel diesel

New insights into astrocyte diversity from the lens of transcriptional regulation and their implications for neurodegenerative disease treatments

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Neural Regeneration Research 2024年第11期19卷 2335-2336页

作者： ibrahim Olabayode Saliu Guoyan Zhao Department of Genetics Washington University School of MedicineSt.LouisMOUSA Department of Neurology Department of Pathology and ImmunologyWashington University School of MedicineSt.LouisMOUSA

Astrocytes are a major glial cell type in the central nervous system,and they provide trophic and metabolic support to *** addition to these roles,they play crucial roles in modulating synaptic functions,development,and pruning(Brandebura et al.,2023).Astrocytes become reactive(activated)by undergoing morphological,molecular,and functional alterations in response to neuropathology such as in injuries and neurodegenerative diseases(NDs)(Escartin et al.,2021).

关键词： degenerative injuries

Analysis of cerium substitution in Co-Sr based spinel ferrites for high frequency application

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Journal of Rare Earths 2024年第9期42卷 1755-1763,I0005页

作者： Laura Khudaysh Inas A.Ahmed Syeda Rabia Ejaz Sajjad Ahmad Khan Yasir A.Haleem Mohamed M.ibrahim Mahmood Ali Hafiz Muhammad Tahir Farid Zeinhom M.el-Bahy Department of Physics Faculty of ScienceJazan UniversityJazan45142Saudi Arabia Department of Chemistry Faculty of ScienceKing Khalid UniversityAbha62224Saudi Arabia Department of Physics The Government Sadiq College Women UniversityBahawalpur63100Pakistan Institute of Physics Khwaja Fareed University of Engineering and Information TechnologyRahim Yar Khan64200Pakistan Department of Chemistry College of ScienceTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Centre of Excellence in Solid State Physics University of the PunjabLahorePakistan Department of Physics Government CollegeTaunsa Sharif32200Pakistan Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr City11884CairoEgypt

Spinel ferrites exhibit exceptional magnetic properties,making them a distinctive class of magnetic *** sol-gel technique was utilized for the synthesis of spinel ferrites with the chemical formula Co_(0.6)Sr_(0.4)Ce_(x)Fe_(2-x)O_(4). Following that,a comprehensive X-ray diffraction analysis unveiled the crystalline cubic structure of the synthesized *** the utilization of the M-H loop approach,the ferromagnetic attributes of ferrites were assessed,and the assimilation of rare earth elements led to substantial enhancements in saturation magnetization,remanence,and *** ferrites with a high concentration of rare earth elements have improved direct current resistivity and activation *** logarithm of a material's resistance increased from 5.29 to 8.12 Ω·cm as cerium is *** a change in the amount of cerium,the activation energy goes up from 0.19 to *** changing the frequency from 5.5 to 9.5 GHz,the dielectric characteristics were *** the frequency goes up,the dielectric constant goes *** ferrites that have been made better in every way can be used in high-frequency applications.

关键词： Activation energy DC electrical resistance Remanence magnetization Cobalt strontium spinel ferrites High frequency application Rare earths

Enteric neuropathy in diabetes:Implications for gastrointestinal function

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World Journal of Gastroenterology 2024年第22期30卷 2852-2865页

作者： Mona Mohamed ibrahim Abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes,commonly known for its metabolic effects,also critically affects the enteric nervous system(ENS),which is essential in regulating gastrointestinal(GI)motility,secretion,and *** development of diabetes-induced enteric neuropathy can lead to various GI dysfunctions,such as gastroparesis and irregular bowel habits,primarily due to disruptions in the function of neuronal and glial cells within the ENS,as well as oxidative stress and *** editorial explores the pathophysiological mechanisms underlying the development of enteric neuropathy in diabetic ***,it discusses the latest advances in diagnostic approaches,emphasizing the need for early detection and intervention to mitigate GI complications in diabetic *** editorial also reviews current and emerging therapeutic strategies,focusing on pharmacological treatments,dietary management,and potential neuromodulatory ***,this editorial highlights the necessity of a multidisciplinary approach in managing enteric neuropathy in diabetes,aiming to enhance patient quality of life and address a frequently overlooked complication of this widespread disease.

关键词： Diabetic neuropathy Gastrointestinal Insulin resistance Diabetes Enteric nervous system Enteric neuropathy

Childhood asthma biomarkers including zinc: An exploratory crosssectional study

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World Journal of Clinical Pediatrics 2024年第1期13卷 31-40页

作者： Hoda Atef Abdelsattar ibrahim Mona Mohsen Boles Salep Aziz Hanna Dina Mahmoud Khaled Mohamed Abdelhamid el-Khashab Pediatric Clinical Nutrition Unit Faculty of MedicineCairo UniversityCairo 12613Egypt Department of Pediatrics Faculty of MedicineCairo UniversityCairo 12613Egypt Department of Clinical Pathology Faculty of MedicineCairo UniversityCairo 12613Egypt

BACKGROUND Childhood bronchial asthma(BA)is a chronic inflammatory respiratory *** conditions,including zinc deficiency,can affect such allergic *** To outline the difference in serum zinc levels between asthmatic children and healthy *** A cross-sectional study was carried out at Children’s Hospital,Cairo University,investigating serum zinc levels in children with BA(n=40)and healthy children(n=21).Other markers included serum ferritin,iron,hemoglobin(Hb),and immunoglobulin E(IgE)*** t-tests and Mann-Whinny tests were used for *** Kruskal-Wallis test was applied to compare serum ferritin and IgE levels with regard to asthma ***'s rank correlation was performed to explore the relationship between serum ferritin levels and both iron and Hb levels in asthmatic *** Children with BA had higher levels of zinc,yet the difference was not significant(P=0.115).Serum ferritin and IgE levels were significantly higher in asthmatic children(P=0.006 and 0.001,respectively),yet their levels did not differ significantly by severity(P=0.623 and 0.126,respectively).There was a nonsignificant weak correlation between serum ferritin levels and both serum iron and Hb *** Serum zinc levels do not seem to differ between asthmatic children and healthy *** ferritin levels may be a marker of asthma *** IgE levels are not markers of asthma severity.

关键词： Children Asthma Zinc Ferritin