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Recent advances in targeted fungicides and immune elicitors for rice blast management

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plant Communications 2024年第9期5卷 5-7页

作者： Huanbin Shi Naweed i.Naqvi Yanjun Kou State Key Laboratory of Rice Biology and Breeding China National Rice Research InstituteHangzhou 311400China Temasek Life Sciences Laboratory and Department of Biological Sciences Research LinkNational University of SingaporeSingapore 117604Singapore

Blast disease,caused by the fungus Magnaporthe oryzae,wreaks havoc on crops worldwide,resulting in an approximate loss of 20%-30%of the annual rice yield(He et al.,2020;Liu et al.,2024).*** heads the top 10 list of the most devastating phytopathogens and serves as a model system for investigating fungal diseases in plants,thus offering insights relevant to disease control in important agricultural crops.

关键词： crops offering insight

post processing of additive manufactured Mg alloys:Current status,challenges,and opportunities

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Journal of Magnesium and Alloys 2024年第4期12卷 1283-1310页

作者： Nooruddin Ansari Fatima Ghassan Alabtah Mohammad i.Albakri Marwan Khraisheh Mechanical Engineering program Texas A&M University at QatarP.O.Box 23874DohaQatar

Magnesium(Mg)and its alloys are emerging as a structural material for the aerospace,automobile,and electronics industries,driven by the imperative of weight *** are also drawing notable attention in the medical industries owing to their biodegradability and a lower elastic modulus comparable to *** ability to manufacture near-net shape products featuring intricate geometries has sparked huge interest in additive manufacturing(AM)of Mg alloys,reflecting a transformation in the manufacturing ***,AM of Mg alloys presents more formidable challenges due to inherent properties,particularly susceptibility to oxidation,gas trapping,high thermal expansion coefficient,and low solidification *** leads to defects such as porosity,lack of fusion,cracking,delamination,residual stresses,and inhomogeneity,ultimately influencing the mechanical,corrosion,and surface properties of AM Mg *** address these issues,post-processing of AM Mg alloys are often needed to make them suitable for *** present article reviews all post-processing techniques adapted for AM Mg alloys to date,including heat treatment,hot isostatic pressing,friction stir processing,and surface *** utilization of these methods within the hybrid AM process,employing interlayer post-processing,is also *** post-processing conditions are reported,and their influence on the microstructure,mechanical,and corrosion properties are ***,future prospects and research directions are proposed.

关键词： Magnesium alloy Additive manufacturing post-processing Heat treatment Hip

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Effectiveness of external prestressing in enhancing the non-ductile hanger failure mechanism in reinforced concrete inverted T-beams

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 1050-1065页

作者： Ahmed M.ATTA Reda N.BEHiRY Mohammed i.HARAZ Structural Engineering Department Faculty of EngineeringTanta UniversityTanta 33511Egypt Nile Higher institute for Engineering and Technology Mansoura 11001Egypt

Recently,inverted T-beams have been used in reinforced concrete(RC)bridges to support transverse precast *** T-beams,contrary to practice with conventional beams,are loaded on the flanges upper *** loading configuration causes hanger failure due to the generation of vertical tensile stresses near the bottom of the *** key purpose of this study is to investigate the efficiency of vertical external prestressing stainless-steel bars in mitigating non-ductile hanger failure in reinforced concrete inverted *** experimental study on six inverted-T beams,including two un-strengthened specimens,was carried *** study showed that the value of the prestressing level had a considerable impact on the performance of hanger mechanism in relation to crack pattern,ultimate loads,cracking behavior,load-deflection,strains,and *** experimental results indicated that the suggested method for strengthening inverted T-beams had efficacy in reducing the seriousness of the non-ductile hanger failure and resulted in a strength increase of up to 53% when compared to that of the un-strengthened ***,two analytical models for estimating the hanger capacity and the average crack width of the strengthened RC inverted T-beams were *** models that were proposed exhibited a high degree of agreement with the experimental results.

关键词： RC bridges inverted T-beams strengthening hanger failure external prestressing

predictive value of neutrophil-to-lymphocyte ratio in in-hospital mortality in sepsis patients:A cross-sectional study

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Journal of Acute Disease 2024年第3期13卷 106-110页

作者： pankaj Kumar jain Manoj Seval Vikas Meena Dinesh Kumar Meena Department of internal Medicine Government Medical CollegeKotaIndia

Objective:To explore the predictive value of neutrophil-to-lymphocyte ratio(NLR)in in-hospital mortality in sepsis ***:A prospective observational cross-sectional study was conducted on 100 patients with *** data about the patient’s demography,medical history,general examination including pulse rate,blood pressure,etc,use of vasopressor support,need for renal replacement therapy,mechanical ventilation,outcome,and lab parameters including total lymphocyte count with neutrophil-to-lymphocyte ratio were *** parameters between survivals and non-survivals were ***:Out of 100 patients,80%were from rural *** patients were 50 to 59 years old.26 patients were *** patients in the nonsurvivor group were older and more had a history of diabetes mellitus when compared with the survivor *** non-survivor group had a higher NLR,ApACHE栻,and SOFA ***:NLR is a readily available parameter and can be used as a good prognostic indicator for mortality in sepsis patients.

关键词： Neutrophil-to-lymphocyte ratio Sepsis intensive Care Unit Mortality ApACHE score SOFA score

immunotherapy in gastric cancer with liver metastasis:Challenges and opportunities

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1513-1516页

作者： Murat Bardakçi Yakup Ergun Department of Medical Oncology Diyarbakır Gazi Yasargil Training and Research HospitalDiyarbakir 021000KayapinarTürkiye Department of Medical Oncology Antalya City HospitalAntalya 07080Türkiye

in this editorial,we review the article by Liu et al published in the World Journal of Gastrointestinal Surgery investigating the efficacy and safety of immunotherapy in patients with gastric cancer(GC)and liver ***,the fifth most com-monly diagnosed malignancy worldwide,presents a significant challenge due to its multifactorial etiology and a grim prognosis for unresectable or recurrent *** advent of immune checkpoint inhibitors(iCis)has revolutionized oncology;yet liver metastasis has been associated with reduced response rates,progression-free survival,and overall survival in various *** Che-ckMate-649 and KEYNOTE-859 trials demonstrated promising results with iCis in advanced GC,particularly in patients with liver ***,a meta-analysis of liver metastatic solid tumors revealed worse outcomes with iCis,high-lighting the need for further *** combined therapies,including iCis with local treatments,show promise in improving outcomes,the nuanced landscape of iCis in liver metastatic GC necessitates continued research for robust *** current contradictions in the literature underscore the impor-tance of cautious interpretation and the exploration of tailored approaches to enhance clinical efficacy in this challenging patient population.

关键词： Gastric cancer Liver metastasis immunotherapy immune checkpoint in-hibitors Transarterial chemoembolization Tumor microenvironment

VR-based digital twin for remote monitoring of mining equipment:Architecture and a case study

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虚拟现实与智能硬件（中英文） 2024年第2期6卷 100-112页

作者： Jovana pLAVŠiĆ ilija MiŠKOViĆNorman BKeevil Norman B.Keevil institute of Mining Engineering University of British ColumbiaVancouverBC V6T 1Z4Canada

Background Traditional methods for monitoring mining equipment rely primarily on visual inspections,which are time-consuming,inefficient,and *** article introduces a novel approach to monitoring mission-critical systems and services in the mining industry by integrating virtual reality(VR)and digital twin(DT)***-based DTs enable remote equipment monitoring,advanced analysis of machine health,enhanced visualization,and improved decision *** This article presents an architecture for VR-based DT development,including the developmental stages,activities,and stakeholders involved.A case study on the condition monitoring of a conveyor belt using real-time synthetic vibration sensor data was conducted using the proposed *** study demonstrated the application of the methodology in remote monitoring and identified the need for further development for implementation in active mining *** article also discusses interdisciplinarity,choice of tools,computational resources,time and cost,human involvement,user acceptance,frequency of inspection,multiuser environment,potential risks,and applications beyond the mining *** The findings of this study provide a foundation for future research in the domain of VR-based DTs for remote equipment monitoring and a novel application area for VR in mining.

关键词： Virtual reality Digital twin Condition monitoring Mining equipment

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Optimization of bio-oil production parameters from the pyrolysis of elephant grass (pennisetum purpureum) using response surface methodology

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Clean Energy 2024年第5期8卷 241-251页

作者： Sunday C.ikpeseni Samuel O.Sada Ufuoma J.Efetobor Henry O.Orugba Mathias Ekpu Hilary i.Owamah Jeremiah L.Chukwuneke Solomon Oyebisi Uche p.Onochie Department of Mechanical Engineering Delta State UniversityP.M.B.1AbrakaNigeria Department of Mechanical Engineering Delta State PolytechnicP.M.B.3Otefe-OgharaNigeria Department of Chemical Engineering Delta State UniversityP.M.B.1AbrakaNigeria Department of Civil Engineering Delta State UniversityP.M.B.1AbrakaNigeria Department of Mechanical Engineering Nnamdi Azikiwe UniversityP.M.B.2025AwkaNigeria Department of Civil Engineering Covenant UniversityP.M.B.1023OttaNigeria Department of Civil Engineering The University of the South PacificP.M.B.9072SuvaFiji Department of Mechanical Engineering Delta State University of Science and TechnologyP.M.B.5OzoroNigeria

The need to increase bio-oil yield from biomass and enhance its fuel properties has driven research into optimizing the pyrolysis *** study investigated the influence of three key process parameters—temperature,heating rate,and nitrogen flow rate—on the pyrolysis of elephant grass(pennisetum purpureum)in a fixed-bed *** surface methodology was used to study the im-pact of the aforementioned variables on bio-oil yield to improve its production *** analysis of the biomass revealed 79.24 wt%volatile matter,14.22 wt%fixed carbon,and 5.86%ash,with ultimate analysis showing 45.44%carbon,5.59%hydrogen,and 40.95%*** high volatile matter content and favourable carbon and hydrogen percentages indicate that elephant grass is a vi-able energy source due to its potential for high bio-oil yield and energy *** resulting bio-oil exhibited a higher heating value of 20.9 MJ/kg,indicating its suitability for various heating applications.A second-order regression model was developed for bio-oil yield,with optimal conditions identified as a temperature of 550°C,a heating rate of 17°C/min,and a nitrogen flow rate of 6 ml/*** study achieved an optimal bio-oil yield of 59.03 wt%,and the model’s high R²value of 0.8683 from analysis of variance analysis confirmed its predictive *** research highlights elephant grass as a sustainable feedstock for bio-oil production,offering valuable insights into optimizing pyrolysis conditions to enhance bio-oil yield,thus advancing biofuel technology.

关键词： renewable energy biomass sustainable feedstock regression model fixed-bed reactor

Landau quantization effects on damping Kawahara solitons in electron–positron–ion plasma in rotating ionized medium

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Communications in Theoretical physics 2024年第10期76卷 143-152页

作者： E i El-Awady S Hussain N Akhtar Department of physics Faculty of Science Port Said University Theoretical physics Division (TpD) PINSTECH

For the dynamics of three-dimensional electron–positron–ion plasmas, a fluid quantum hydrodynamic model is proposed by considering Landau quantization effects in dense ***–neutral collisions in the presence of the Coriolis force are also considered. The application of the reductive perturbation technique produces a wave evolution equation represented by a damped Korteweg–de Vries equation. This equation, however, is insufficient for describing waves in our system at very low dispersion coefficients. As a result, we considered the highest-order perturbation, which resulted in the damped Kawahara equation. The effects of the magnetic field, Landau quantization, the ratio of positron density to electron density, the ratio of positron density to ion density, and the direction cosine on linear dispersion laws as well as soliton and conoidal solutions of the damped Kawahara equation are explored. The understanding from this research can contribute to the broader field of astrophysics and aid in the interpretation of observational data from white dwarfs.

关键词： Coriolis force Kawahara equation Landau quantization magnetoplasmas quantum plasma solitary and cnoidal waves

Botulinum toxin type A for treating chronic low back pain:A double blinded randomized control study

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World Journal of Methodology 2024年第3期14卷 119-125页

作者： Mantu jain Shahnawaz Khan paulson Varghese Sujit Kumar Tripathy Manaswini Mangaraj Department of Orthopaedics All India Institute of Medical SciencesBhubaneswar 751019OdishaIndia Department of Biochemistry All India Institute of Medical SciencesBhubaneswar 751019OdishaIndia

BACKGROUND Low back pain(LBp)is a prevalent issue that orthopedic surgeons frequently address in the outpatient *** can arise from various causes,with stiffness in the paraspinal muscles being a notable *** administration of Botulinum toxin type A(BoNT-A)has been found to alleviate back pain by relaxing these stiff *** BoNT-A is approved for use in numerous conditions,a limited number of randomized clinical trials(RCTs)validate its efficacy specifically for treating *** To study the safety and the efficacy of BoNT-A in minimizing pain and improving functional outcomes in patients of chronic LBp(CLBp).METHODS in this RCT,adults aged 18-60 years with mechanical LBp persisting for at least six months were *** were allocated to either the Drug group,receiving 200 ipsen Units(2 mL)of BoNT-A,or the Control group,which received a 2 mL *** a 2-month follow-up period,both groups were assessed using the Visual Analog Scale(VAS)for pain intensity and the Oswestry Disability index(ODi)for disability at the start and conclusion of the study.A decrease in pain by 50%was deemed clinically *** The study followed 40 patients for two months,with 20 in each group.A clinically significant reduction in pain was observed in 36 *** was a statistically significant decrease in both VAS and ODi scores in the groups at the end of two ***,when comparing the mean score changes,only the reduction in ODi scores(15 in the placebo group vs 16.5 in the drug group,clinically insignificant)was statistically significant(p=0.012),whereas the change in mean VAS scores was not significant(p=0.45).CONCLUSiON The study concludes that BoNT-A does not offer a short-term advantage over placebo in reducing pain or improving LBp scores in CLBp patients.

关键词： Botulinum toxin type A Chronic low back pain Randomized control study Double-blinded pain management Therapeutic efficacy