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Chi.ese Chemi.al Letters 1995年第1期6卷 19-22页

作者： Yu Gui.Li.Xue Feng ZHU i.sti.ute of Elemento-Organi. Chemi.try, Nanka i.Uni.ersi.y,Ti.nji., 300071 Nankai.Uni. Inst Elementoorgan Chem Tianjin 300071 Peoples R China

N- (1 -oxo-4-carbony 1-2. 6, 7- tri.xa- 1 -phosphabi.yclo[2. 2. 2] octane) - N- aryl thi.ureas (4)were syntbesi.ed i. thi. paper. (4) reacted,wi.h AgNO3-H2O and chloroacetyl cblor i.e to afford the correspondi.g urea heri.ati.es (5) and cycli. zed produets (10), respecti.ely, The mechani.m of desulphuri.ati.n of (4) bas also been studi.d.

关键词： OXO CARBONYL OF REACTi.NS ARYL AND

钙、镁离子对铁矿石中选择性脱泥和石英的阳离子浮选的影响

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国外金属矿选矿 1981年第1期 29-38页

作者： i.i.asaki.K.A.Smi.h 孙中溪明尼苏达州明尼阿波利斯城明尼苏达大学矿物资源研究中心

选择性脱泥使低品位细粒嵌布不适合传统浮选的铁矿石的富集有更大希望了。这种工艺对于生产用水中存在的或从组成矿物溶解下来的钙镁离子非常敏感。通过流动电位测定、絮凝和阳离子浮选试验、萃取试验以及电子扫描显微镜研究,比较了这... 详细信息

选择性脱泥使低品位细粒嵌布不适合传统浮选的铁矿石的富集有更大希望了。这种工艺对于生产用水中存在的或从组成矿物溶解下来的钙镁离子非常敏感。通过流动电位测定、絮凝和阳离子浮选试验、萃取试验以及电子扫描显微镜研究,比较了这两种碱土金属离子对石英的影响。钙离子以CaoH+吸附,因异类粒子凝聚附着的镁离子作为Mg（OH）2沉淀呈现出来,对于石英悬浮液的絮凝和碱性矿浆中抑制阳离子浮选硅起很大作用。和吸附钙离子一样,镁的氢氧化物罩盖可以用EDTA和聚磷酸盐络合而除去。

关键词：悬浮液絮凝化工单元操作化学计算量聚磷酸盐离子浮选氯化镁卤块氯化物阳离子正离子石英硅氧矿物平衡浓度针铁矿铁矿物脱泥铁矿石

Dopi.g-i.duced Phase Transi.i.ns i. Polycrystalli.e La0.49Sr0.51（Mn1-xNbx）O3

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Chi.ese Physi.s Letters 2005年第4期22卷 938-941页

作者：柳文军舒启清马晓翠 S.M.Bhagat S.E.Lofland i.O.Troyanchuk DepartmentofMateri.lSci.nceandEngi.eeri.g SchoolofScienceShenzhenUniversityShenzhen518060//ShenzhenKeyLaboratoryofSpecialFunctionalMaterialsShenzhenUniversityShenzhen518060 DepartmentofPhysi.s UniversityofMarylandCollegeParkMaryland20742-4111USA i.sti.uteofSoli.StatePhysi.s NationalAcademyofSciencesofBelarusP.BrovkiStreet17Minsk220072Belarus

Observati.ns of temperature dependences of ac suscepti.i.i.y x(ac),resi.ti.i.y (p) and dc magneti.ati.n M for polycrystalli.e La0.49Sr0.51(Mn1-xNbx)O-3 (x = 0, 0.05,0.15, and 0.25) show that due to substi.ui.n of Mn4+ by di.magneti. Nb5+, there appear to be (i. thedecrease of x(ac) as T > T-N, (i.) the occurrence of a maxi.um (i.sulator-metal-li.e transi.i.n)for rho near T-C, (i.i. the decli.e of M as x > 0.05, and (i.) the loweri.g of T-C. The resultsmi.ht be ascri.ed to: (i. the rearrangement of Mn3+ and Mn4+ i.ns, (i.) the decrease of the numberof Mn3+ and Mn4+ pai.s i.volved i. double exchange i.teracti.n, (i.i. the delocali.ati.n of theelectrons and holes, (i.) the reducti.n of the randomness of the delocali.ed carri.r scatteri.g bythermal spi. fluctuati.n due to magneti. orderi.g, and (v) the compensati.n effect of Nb5+ i.ns forSr2+ i.ns.

关键词： TRANSPORT-PROPERTi.S DOPED MANGANi.ES LA1-XSR(X)MNO3 CHARGE

Explori.g the i.pact of tacroli.us on ki.ney transplant reci.i.nts:i.si.hts i.to i.munologi.al outcomes

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Journal of Chi.ese Pharmaceuti.al Sci.nces 2024年第8期33卷 737-750页

作者： Zai.ab A Abbood Ahmed Hamza AL-Shammari.Eman M.Jasi. Amjad i.Orai.i Department of Pharmacy Kut University CollegeAlkutWasitIraq52001 AL-Manara College For Medi.al Sci.nce/Department of Pharmacy MisanIraq62001

To mi.i.i.e graft rejecti.n,i. i. cruci.l to reduce *** the present study,we i.vesti.ated i.munologi.al markers i. the blood of transplant pati.nts who di. not recei.e *** also assessed alloreacti.e CD4+CD25+FoxP3+ Tregs both before transplantati.n and after tacroli.us *** comparati.e analysi. i.cluded 50 i.di.i.uals experi.nci.g early rejecti.n after tacroli.us di.conti.uati.n and 100 *** reduci.g tacroli.us,rejectors exhi.i.ed elevated levels of memory CD8+T cells compared to Tregs,whi.e non-rejectors di.played a lower rati. of memory CD4+T cells to *** tacroli.us removal,rejectors showed an i.crease i. naïve T cells and a decrease i. effector T *** transplantati.n,CD4+Treg levels decli.ed,but thei. anti.donor regulatory functi.n remai.ed consi.tent i. both rejectors and *** correlati.n revealed an associ.ti.n between acute rejecti.n after tacroli.us di.conti.uati.n and the pre-reducti.n rati. of memory T cells to regulatory T *** i.di.ators i.enti.i.d i.di.i.uals whose i.munosuppressi.n could be safely reduced.

关键词： Tacroli.us Ki.ney Transplant i.mune system Rejecti.n

Epi.emi.logy and natural hi.tory of hepati.i. C vi.us i.fecti.n

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World Journal of Gastroenterology 2014年第28期20卷 9270-9280页

作者： Mei.Hsuan Lee Hwai.i.Yang Yong Yuan Gi.bert L’i.ali.n Chi.n-Jen Chen the i.sti.ute of Cli.i.al Medi.i.e National Yang-Ming University the Genomi.s Research Center Academia Sinica the Graduate i.sti.ute of Cli.i.al Medi.al Sci.nce China Medical University the Molecular and Genomi. Epi.emi.logy Center China Medical University Hospital the Global Health Economi.s and Outcomes Research Bristol-Myers SquibbPrincetonNJ 08543United States the Yale Uni.ersi.y School of Medi.i.e the Graduate i.sti.ute of Epi.emi.logy and Preventi.e Medi.i.e College of Public HealthNational Taiwan University

Hepati.i. C vi.us(HCV)affects 130-210 mi.li.n people worldwi.e and i. one of the major ri.k factors for hepatocellular ***,at least one thi.d of hepatocellular carci.oma cases are attri.uted to HCV i.fecti.n,and 350000 people di.d from HCV related di.eases per *** i. a great geographi.al vari.ti.n of HCV i.fecti.n globally,wi.h ri.k factors for the HCV i.fecti.n di.feri.g i. vari.us *** progressi.n of chroni. hepati.i. C to end-stage li.er di.ease also vari.s i. di.ferent study populati.ns.A long-term follow-up cohort enrolli.g parti.i.ants wi.h asymptomati. HCV i.fecti.n i. essenti.l for eluci.ati.g the natural hi.tory of HCV-caused hepatocellular carci.oma,and for explori.g potenti.l seromarkers that have hi.h predi.tabi.i.y for ri.k of hepatocellular ***,prospecti.e cohorts compri.i.g i.di.i.uals wi.h HCV i.fecti.n are sti.l *** ri.k evaluati.n of vi.al load elevati.n and associ.ted li.er di.ease/cancer i. HCV(REVEAL-HCV)study has followed a cohort of 1095 resi.ents seroposi.i.e for anti.odi.s agai.st hepati.i. C vi.us li.i.g i. seven townshi.s i. Tai.an for more than fi.teen *** of them have acqui.ed HCV i.fecti.n through i.trogeni. transmi.si.n *** the parti.i.ants i. the REVEALHCV study rarely recei.e anti.i.al therapi.s,i. provi.es a uni.ue opportuni.y to study the natural hi.tory of chroni. HCV *** thi. revi.w,the prevalence,ri.k factors and natural hi.tory of HCV i.fecti.n are comprehensi.ely *** study cohort,data collecti.n,and fi.di.gs on li.er di.ease progressi.n of the REVEAL-HCV study are descri.ed.

关键词： Hepati.i. C vi.us Epi.emi.logy Ri.k evaluati.n of vi.al load elevati.n and associ.ted li.er di.ease/cancer Long-term li.er progressi.n

STERi. MAPPi.G OF RECEPTOR Si.E:STERi. Di.FERENCE METHOD AND APPLi.ATi.NS

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Chi.ese Sci.nce Bulleti. 1981年第4期26卷 361-367页

作者： i.MOTOC i.MUSCUTARi. D.Ci.BOTARi. Chemi.try Research Center M.Viteazul 241990 Timisoara 5RomaniaDepartment of Physicsthe University1990 TimisoaraRomaniaDepartment of Organic Chemistrythe Polytechnic1990 TimisoaraRomania

The current methods avai.able to map the receptor si.e make use of E_s-type steri. constant (for a revi.w, see Ref. [1]). Thi. approach of the steri. effects i. the effector—bi.logi.al receptor i.teracti.ns i. restri.ted to the congeners seri.s of bi.acti.e molecules. The present paper descri.es a new approach of thi. problem, namely

关键词： steri. restri.ted effector bi.acti.e QSAR analogous assumpti.ns abbrevi.ted 吕忱 steps

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务实的理想主义

商界(评论) 2006年第1期 105-106+104页

作者：詹姆斯·C·柯林斯杰里·i.波拉斯斯坦福大学商学院

这篇文章来自于《基业长青》,我比较赞同其中的某些观点,当你把公司的理想定得更高,而不是把利润放在唯一的首位时,会获得更大的利润。记得有这样一个故事:一只小狮子问老狮子:“幸福在哪里?”老狮子回答说:“幸福就在你的尾巴尖上。”... 详细信息

这篇文章来自于《基业长青》,我比较赞同其中的某些观点,当你把公司的理想定得更高,而不是把利润放在唯一的首位时,会获得更大的利润。记得有这样一个故事:一只小狮子问老狮子:“幸福在哪里?”老狮子回答说:“幸福就在你的尾巴尖上。”于是小狮子转着圈地追着自己的尾巴跑,但是怎么也抓不到自己的尾巴尖。老狮子看着小狮子顽皮的样子,意味深长地笑了,说:“你试一试只管向前跑,不要管你的尾巴。”于是小狮子努力向前跑,飞快的速度令小狮子的尾巴在他身后快活地飘动。老狮子说:“小狮子呀,你看,幸福在追着你跑呢!”这个故事中的小狮子就像是一个“务实的理想主义”者。可以认为尾巴尖上的幸福是利润,而他的前方,有他的理想,那么,当他眼中只有利润,只想追求利润时,利润会扑朔迷离,很难追到,而当他为了理想快步奔跑时,利润反而尾随而来。做企业也是这样,利润的“幸福”在尾巴尖上,理想的“幸福”在前方,如果眼中只有利润,一切为了利润,会容易忽视一些本该遵守的道德原则,最终会迷失自我、失道寡助。如果一个企业仅仅是想做个企业,那么,他就会很容易只看到“尾巴尖上的幸福”,如果一个企业是想把企业做成一个事业,那么,他通常会注意“前方的幸福”。我觉得做企业还是该有一些更为美好,更为高远的理想,当你为伟大的事业而快步奔跑时,利润自会滚滚而来。但是,我所指的理想是美好的事业,对社会有益的事业,并不是要求企业承担更多不必要的社会责任,这点一定要分清。

关键词：幸福故事企业民间文学企业管理小狮子利润财政管理理想主义

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胃内折叠缝合术的预后预测指标

世界核心医学期刊文摘（胃肠病学分册） 2005年第6期1卷 59-60页

作者： Schi.fke i. Soeder H. Zabel-Langhenni. A. 王志宇 Dept. of i.ternal Medi.i.e i. University of Leipzig Leipzig Germany

Background: Endolumi.al gastropli.ati.n (EndoCi.ch) has emerged as an endoscopi. anti.reflux therapy, but predi.ti.e factors for symptom reli.f have not been establi.hed. The ai. of thi. study was to evaluate the major determi.ants to predi.t outcome i. pati.nts treated wi.h EndoCi.ch. Methods: A total of 53 consecuti.e pati.nts, treated wi.h EndoCi.ch at a si.gle center were i.cluded i. thi. prospecti.e study. i.clusi.n cri.eri. were symptoms of chroni. heartburn, dependency on proton-pump i.hi.i.ors, documented pathologi.al esophageal aci. exposure, and a hi.tal herni. smaller than 3 cm i. length. All pati.nts underwent endoscopy, 24-h pH moni.ori.g, esophageal manometry, bari.m esophagram, and a detai.ed questi.nnai.e regardi.g thei. symptoms before treatment. Pati.nts were strati.i.d i.to a responder and a non-responder group usi.g a questi.nnai.e at 3-month follow-up. A multi.ari.te analysi. was performed. Results: The success rate was 64%(34/53 pati.nts). Three vari.bles were si.ni.i.antly predi.ti.e for successful endoscopi. anti.reflux treatment at the multi.ari.te level: presence of typi.al symptoms (P = 0.01), complete symptom reli.f wi.h aci. suppressi.e therapy (P = 0.01), and normal lower esophageal sphi.cter pressure (P = 0.04). Not predi.ti.e of outcome were age, body mass i.dex, esophagi.i., other manometri. fi.di.gs, hi.tal herni. si.e, or pathologi.al level of pH i.m esophagram di. not add any addi.i.nal predi.ti.e i.formati.n. Conclusi.ns: Si.ce no si.gle factor can predi.t outcome after EndoCi.ch, a careful pati.nt selecti.n i. mandatory to maxi.i.e the success rate. The i.eal candi.ate for EndoCi.ch i. a gastroesophageal (GERD) pati.nt wi.h a normal lower esophageal sphi.cter pressure, whose typi.al symptoms completely resolved wi.h aci. suppressi.e therapy.

关键词：缝合术预后预测食管钡餐造影抑酸治疗食管测压食管下括约肌裂孔疝胃食管反流预测意义食管炎

动脉血去甲肾上腺素水平可独立于血压和体格预测20年内发生高血压患者的左室质量

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世界核心医学期刊文摘（心脏病学分册） 2006年第7期2卷 61-62页

作者： Strand A.H. Gudmundsdotti. H. Os i. 张步升 Department of Cardi.logy Ullevaal University Hospital Kirkevn 166 N-0407 Oslo Norway Dr.

Background: i.creased sympatheti. acti.i.y may be an underlyi.g mechani.m i. cardi.vascular di.ease. i. has been hypothesi.ed that the degree of left ventri.ular(LV) hypertrophy i. partly related to the blood pressure level, and partly to neurohormonal factors. The ai. of thi. study was to i.vesti.ate predi.tors of LV mass, i.cludi.g arteri.l plasma noradrenali.e as an i.dex of sympatheti. acti.i.y, wi.h parti.ular emphasi. on subjects who developed hypertensi.n over a peri.d of 20 years. Methods: i. a 20-year prospecti.e study of mi.dle-aged men, sustai.ed hypertensi.es(n=22), new hypertensi.es(crossovers)(n=17) and sustai.ed normotensi.es(controls)(n=17) were exami.ed both at baseli.e and after 20 years of follow-up(at ages 42.1±0.5 and 62.3±0.6 years, respecti.ely). Relati.nshi.s between arteri.l plasma catecholami.es, blood pressure and body mass i.dex at baseli.e to left ventri.ular parameters by echocardi.graphy at follow-up were i.vesti.ated. Results: Groups were homogeneous regardi.g age, gender, race and body bui.d. The group of sustai.ed hypertensi.es had si.ni.i.antly more LV hypertrophy(P=0.025) and di.stoli. dysfuncti.n(P=0.010). Among the crossovers, LV mass i.dex was posi.i.ely correlated to arteri.l plasma noradrenali.e(r=0.50, P=0.043) and body mass i.dex(BMi.(r=0.51, P=0.039) and showed a posi.i.e trend wi.h systoli. blood pressure(SBP) at baseli.e. Arteri.l plasma noradrenali.e(β=0.47)was found to predi.t LV mass i.dex after 20 years i.dependently of BMi.β=0.45) and SBP(β=0.22) at baseli.e(R2 adjusted=0.345, P=0.037). Such a relati.nshi. was not found i. the controls or i. the sustai.ed hypertensi.es, of whi.h 16 were treated wi.h anti.ypertensi.e drugs. Conclusi.ns: Arteri.l plasma noradrenali.e at baseli.e, as an i.dex of sympatheti. acti.i.y, predi.ts LV mass at followup i.dependently of systoli. blood pressure and body bui.d i. mi.dle-aged men who developed hypertensi.n over a peri.d of 20 years.

关键词：左室质量去甲肾上腺素交感神经活性抗高血压药物左室肥厚心血管疾病神经激素舒张功能障碍中

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人的丘脑在处理伴随放电时的作用

世界核心医学期刊文摘(眼科学分册) 2005年第9期 3-4页

作者： Bellebaum C. Daum i. Koch B. 陈立军 i.sti.ute of Cogni.i.e Neurosci.nce Dept. of Neuropsychology Ruhr-University of Bochum 44780 Bochum Germany

Corollary di.charge si.nals play an i.portant role i. moni.ori.g self-generated movements to guarantee spati.l constancy. Recent work i. macaques suggests that the thalamus conveys corollary di.charge i.formati.n of upcomi.g saccades passi.g from the superi.r colli.ulus to the frontal eye fi.ld. The present study ai.ed to i.vesti.ate the i.volvement of the thalamus i. humans by assessi.g the effect of thalami. lesi.ns on the processi.g of corollary di.charge i.formati.n. Thi.teen pati.nte wi.h selecti.e thalami. lesi.ns and 13 healthy age-matched control subjects performed a saccadi. double-step task i. whi.h rei.no-spati.l di.sonance was i.duced, i.e. the reti.al vector of the second target and the movement vector of the second saccade were di.ferent. Thus, the subjects could not rely on reti.al i.formati.n alone, but had to use corollary di.charge i.formati.n to correctly perform the second saccade. The ampli.udes of fi.st and second saccades were si.ni.i.antly smaller to pati.nts than i. controls. Fi.e thalami. lesi.n pati.nts showed uni.ateral defi.i.s i. usi.g corollary di.charge i.formati.n, as revealed by asymmetri.s compared wi.h the other pati.nts and controls. Three pati.nts wi.h lateral thalami. lesi.ns i.cludi.g the ventrolateral nucleus (VL) were i.pai.ed contralaterally to the si.e of damage and one pati.nt wi.h a lesi.n i. the medi.dorsal thalamus (MD) was i.pai.ed i.si.aterally to the lesi.n. The largest asymmetry was found i. a pati.nt wi.h a bi.ateral thalami. lesi.n. The results provi.e evi.ence for a thalami. i.volvement i. the processi.g of corollary di.charge i.formati.n to humans, wi.h a potenti.l role of both the VL and MD nuclei.

关键词：丘脑间脑病变不对称