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Radical innovation breakthroughs of biodegradation of plastics by insects:history,present and future perspectives

Frontiers of Environmental Science & Engineering 2024年第6期18卷 127-165页

作者： Shan-Shan Yang Wei-Min Wu Federica Bertocchini Mark Eric Benbow Suja P.Devipriya hyung joon cha.bo-yu peng Meng-Qi Ding Lei He Mei-Xi Li Chen-Hao Cui Shao-Nan Shi Han-Jun Sun Ji-Wei Pang Defu He Yalei Zhang Jun Yang Deyi Hou De-Feng Xing Nan-Qi Ren Jie Ding Craig S.Criddle State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin 150090China Department of Civil and Environmental Engineering William&Cloy Codiga Resource Recovery CenterStanford UniversityStanfordCA 94305USA Plasticentropy rue Thiers 28Reims 51100France Department of Entomology and Department of Osteopathic Medical Specialties Michigan State UniversityEast LansingMI 48824USA School of Environmental Studies Cochin University of Science and TechnologyKochi 682022India Department of Chemical Engineering Pohang University of Science and TechnologyPohang 37673Republic of Korea School of Environmental Science and Engineering Tongji UniversityShanghai 200092China China Energy Conservation and Environmental Protection Group CECEP Talroad Technology Co.Ltd.Beijing 100096China School of Ecological and Environmental Sciences East China Normal UniversityShanghai 200241China Research Institute for Frontier Science Beihang UniversityBeijing 100191China School of Environment Tsinghua UniversityBeijing 100084China

Insects damaging and penetrating plastic packaged materials has been reported since the *** innovation breakthroughs of plastic biodegradation have been initiated since the discovery of biodegradation of plastics by Tenebrio molitor larvae in 2015 followed by Galleria mellonella in *** we review updated studies on the insect-mediated biodegradation of *** biodegradation by insect larvae,mainly by some species of darkling beetles(Tenebrionidae)and pyralid moths(Pyralidae)is currently a highly active and potentially transformative area of *** the past eight years,publications have increased explosively,including discoveries of the ability of different insect species to biodegrade plastics,biodegradation performance,and the contribution of host and microbiomes,impacts of polymer types and their physic-chemical properties,and responsible enzymes secreted by the host and gut *** date,almost all major plastics including polyethylene(PE),polypropylene(PP),polyvinyl chloride(PVC),polyethylene terephthalate(PET),polyurethane(PUR),and polystyrene(PS)can be biodegraded by *** and ten other insect species representing the Tenebrionidae and Pyralidae *** biodegradation processes are symbiotic reactions or performed by synergistic efforts of both host and gut-microbes to rapidly depolymerize and biodegrade plastics with hourly *** digestive ezymens and bioreagents screted by the insects play an essential role in plasatic biodegradation in certain species of Tenebrionidae and Pyralidae *** research on the insect itself,gut microbiomes,transcriptomes,proteomes and metabolomes has evaluated the mechanisms of plastic biodegradation in *** conclude this review by discussing future research perspectives on insect-mediated biodegradation of plastics.

关键词： Plastics Biodegradation Insects Gut microbiomes Enzymes

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Callus proliferation-induced hypoxic microenvironment decreases shoot regeneration competence in Arabidopsis

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Molecular Plant 2024年第3期17卷 395-408页

作者： Dohee Koo Hong Gil Lee Soon hyung Bae Kyounghee Lee Pil joon Seo Department of Chemistry Seoul National UniversitySeoul 08826Korea Plant Genomics and Breeding Institute Seoul National UniversitySeoul 08826Korea Research Institute of Basic Sciences Seoul National UniversitySeoul 08826Korea

Plants are aerobic organisms that rely on molecular oxygen for respiratory energy *** conditions,with oxygen levels ranging between 1%and 5%,usually limit aerobic respiration and affect plant growth and ***,we demonstrate that the hypoxic microenvironment induced by active cell proliferation during the two-step plant regeneration process intrinsically represses the regener-ation competence of the callus in Arabidopsis *** showed that hypoxia-repressed plant regener-ation is mediated by the RELATED TO APETALA2.12(RAP2.12)protein,a memberof the Ethylene Response Factor VIl(ERF-Vll)*** found that the hypoxia-activated RAP2.12 protein promotes salicylic acid(SA)biosynthesis and defense responses,thereby inhibiting pluripotency acquisition and de novo shoot regeneration in *** and genetic analyses revealed that RAP2.12 could bind directly to the SALICYLIC ACID INDUCTION DEFICIENT 2(SID2)gene promoter and activate SA biosynthesis,repressing plant regeneration possibly via a PLETHORA(PLT)-dependent ***,the rap2.12 mutant calli exhibits enhanced shoot regeneration,which is impaired by SA *** together,these find-ings uncover that the cell proliferation-dependent hypoxic microenvironment reduces cellular pluripotency and plant regeneration through the RAP2.12-SID2 module.

关键词： callus cell proliferation-induced hypoxia SID2 plant regeneration salicylic acid RAP2.12

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Neural Wiskott-Aldrich syndrome protein(N-WASP)promotes distant metastasis in pancreatic ductal adenocarcinoma via activation of LOXL2

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Oncology Research 2024年第4期32卷 615-624页

作者： hyung SUN KIM yuN SUN LEE SEUNG MyuNG DONG HYO JUNG KIM DA EUN LEE HYEON WOONG KANG MYEONG JIN KIM joon SEONG PARK Department of Surgery Gangnam Severance HospitalYonsei University College of MedicineSeoulKorea Department of Surgery Graduate School of Medical ScienceBrain Korea 21 ProjectYonsei University College of MedicineSeoulKorea Gibiome Co. Ltd.Gyeonggi-doKorea

Pancreatic ductal adenocarcinoma(PDAC)is one of the most aggressive solid malignancies.A specific mechanism of its metastasis has not been *** this study,we investigated whether Neural Wiskott-Aldrich syndrome protein(N-WASP)plays a role in distant metastasis of *** found that N-WASP is markedly expressed in clinical patients with *** analysis showed a notably more distant metastatic pattern in the N-WASP-high group compared to the N-WASP-low group.N-WASP was noted to be a novel mediator of epithelialmesenchymal transition(EMT)via gene expression profile *** of N-WASP in pancreatic cancer cells significantly inhibited cell invasion,migration,and *** also observed positive association of lysyl oxidase-like 2(LOXL2)and focal adhesion kinase(FAK)with the N-WASP-mediated response,wherein EMT and invadopodia function were *** N-WASP and LOXL2 depletion significantly reduced the incidence of liver and lung metastatic lesions in orthotopic mouse models of pancreatic *** results elucidate a novel role for N-WASP signaling associated with LOXL2 in EMT and invadopodia function,with respect to regulation of intercellular communication in tumor cells for promoting pancreatic cancer *** findings may aid in the development of therapeutic strategies against pancreatic cancer.

关键词： Pancreatic cancer Neural Wiskott-Aldrich syndrome protein(N-WASP)signaling Metastasis Epithelial-mesenchymal transition(EMT) Lysyl oxidase-like 2(LOXL2)

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Regional anesthesia in a patient with primary ciliary dyskinesia:A case report

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World Journal of Clinical Cases 2024年第17期12卷 3183-3187页

作者： hyung joon Park Ye Hwan Kim Young joon Yoon Sang yun Cho Department of Anesthesiology and Pain Medicine Hanyang University Guri HospitalGuri-si 471-701Gyeonggi-doSouth Korea

BACKGROUND Primary ciliary dyskinesia(PCD)is an inherited autosomal-recessive disorder of impaired mucociliary clearance characterized by chronic respiratory diseases,otolaryngological diseases,central nervous system abnormalities,reproductive system abnormalities,and cardiac function *** anesthesia in these patients is associated with a higher incidence of respiratory complications than in patients without the *** SUMMARY A 16-year-old male patient was referred to the emergency room complaining of right ankle pain due to distal tibiofibular *** years prior,he had been diagnosed with *** that time,he had experienced several episodes of pneumonia,sinusitis,and chronic middle ear infections,for which he underwent surgical *** the current admission,he presented with cough and sputum but no other respiratory symptoms.A chest computed tomography scan revealed centrilobular ground-glass opacities in both lower lobes and a calcified nodule in the left lower *** the surgical procedure and postoperative pain management,combined spinal-epidural anesthesia was *** patient’s postoperative pain score was measured by the numerical rating scale(NRS).On the day of surgery,his NRS was 5 *** the second postoperative day,the NRS score had decreased to 2–3 *** epidural catheter was removed on the fourth day following the *** patient was subsequently discharged no respiratory *** We performed combined spinal-epidural anesthesia in a patient with *** patient experienced no additional respiratory complications and was discharged with a low NRS score for pain.

关键词： Primary ciliary dyskinesia Combined spinal-epidural anesthesia Patient controlled epidural analgesia Lower limb operation Case report

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Real-Time Tunable Gas Sensing Platform Based on SnO_(2) Nanoparticles Activated by Blue Micro-Light-Emitting Diodes

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Nano-Micro Letters 2024年第12期16卷 103-119页

作者： Gi Baek Nam Jung-El Ryu Tae Hoon Eom Seung Ju Kim Jun Min Suh Seungmin Lee Sungkyun Choi Cheon Woo Moon Seon Ju Park Soo Min Lee Byungsoo Kim Sung Hyuk Park Jin Wook Yang Sangjin Min Sohyeon Park Sung Hwan Cho Hyuk Jin Kim Sang Eon Jun Tae hyung Lee Yeong Jae Kim Jae Young Kim Young joon Hong Jong-In Shim hyung-Gi Byun Yongjo Park Inkyu Park Sang-Wan Ryu Ho Won Jang Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Republic of Korea Research Laboratory of Electronics Department of Mechanical EngineeringMassachusetts Institute of TechnologyCambridgeMA 02139USA Ming Hsieh Department of Electrical and Computer Engineering University of Southern CaliforniaLos AngelesCA 90089USA Department of Display Materials Engineering Soonchunhyang UniversityAsan 31538Republic of Korea Department of Photonics and Nanoelectronics BK21 FOUR ERICA-ACE CenterHanyang University ERICAAnsan 15588Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea Department of Electronics Information and Communication EngineeringKangwon National UniversitySamcheok 25913Republic of Korea Advance Institute of Convergence Technology Seoul National UniversitySuwon 16229Republic of Korea Department of Mechanical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Department of Physics Chonnam National UniversityGwangju 500-757Republic of Korea

Micro-light-emitting diodes(μLEDs)have gained significant interest as an activation source for gas sensors owing to their advantages,including room temperature operation and low power ***,despite these benefits,challenges still exist such as a limited range of detectable gases and slow *** this study,we present a blueμLED-integrated light-activated gas sensor array based on SnO_(2)nanoparticles(NPs)that exhibit excellent sensitivity,tunable selectivity,and rapid detection with micro-watt level power *** optimal power forμLED is observed at the highest gas response,supported by finite-difference time-domain ***,we first report the visible light-activated selective detection of reducing gases using noble metal-decorated SnO_(2)*** noble metals induce catalytic interaction with reducing gases,clearly distinguishing NH3,H2,and ***-time gas monitoring based on a fully hardwareimplemented light-activated sensing array was demonstrated,opening up new avenues for advancements in light-activated electronic nose technologies.

关键词： Micro-LED Gas sensor array Low power consumption Metal decoration Real-time detection

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Unleashing the potential of morphotropic phase boundary based hybrid triboelectric–piezoelectric nanogenerator

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Journal of Materiomics 2024年第4期10卷 792-802页

作者： Sugato Hajra Aneeta Manjari Padhan Basanta Kumar Panigrahi Phakkhananan Pakawanit Zvonko Jagličić Naratip Vittayakorn Yogendra Kumar Mishra Sanghoon Lee Hoe joon Kim Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and TechnologyDaegu42988Republic of Korea Department of Electrical Engineering Siksha O Anusandhan UniversityBhubaneswar751030India Synchrotron Research and Applications Division Synchrotron Light Research InstituteNakhon Ratchasima30000Thailand Institute of Mathematics Physics and Mechanics&Faculty of Civil and Geodetic EngineeringUniversity of LjubljanaJadranska191000LjubljanaSlovenia Advanced Materials Research Unit Department of ChemistrySchool of ScienceKing Mongkut's Institute of Technology LadkrabangBangkok10520Thailand Mads Clausen Institute NanoSYDUniversity of Southern DenmarkAlsion 26400SønderborgDenmark Robotics and Mechatronics Research Center Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu42988Republic of Korea

Morphotropic phase boundary(MPB)-based ceramics are excellent for energy harvesting due to their enhanced physical properties at phase boundaries,broad operating temperature range,and ability to customize properties for efficient conversion of mechanical energy into electrical *** this work,Bi_(1–x)Na_(x)Fe_(1–x)Nb_(x)O_(3)(x=0.20,0.30,0.32 and 0.40,BNFNO abbreviation)based ceramics were synthesized using a solid-state route and blended with Polydimethylsiloxane(PDMS)to achieve flexible *** material characterization and energy harvesting were performed by designing a hybrid piezoelectric(peng)-triboelectric(TENG)*** voltage and current of peng,TENG,and hybrid bearing same device area(2 cm×2 cm)were recorded as 11 V/0.3μA;60 V/0.7μA;110 V/2.2μ*** strategies for enhancing the output performance of the hybrid device were evaluated,such as increased surface area(creating micro-roughness and porous morphology)and increasing electrode size and multi-layer hybrid device *** self-powered acceleration monitoring was demonstrated using the hybrid ***,the low-frequency-based wave energy is converted into electrical energy,confirming the usage of hybrid peng-TENG devices as a base for battery-free sensors and blue energy harvesting.

关键词： Lead-free Acceleration Wave energy Morphotropic

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Reply to comment on “Ferroelectric composite-based piezoelectric energy harvester for self-powered detection of obstructive sleep” by A. Tkach and O. Okhay

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Journal of Materiomics 2024年第5期10卷 1160-1164页

作者： Swati Panda Hyoju Shin Sugato Hajra yumi Oh Wonjeong Oh Jeonghyeon Lee P.M.Rajaitha Basanta Kumar Panigrahi Jyoti Shukla Alok Kumar Sahu Perumal Alagarsamy Hoe joon Kim Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988South Korea Department of Electrical Engineering Siksha‘O’Anusandhan UniversityBhubaneswar 751030India Department of Electrical Engineering Poornima College of EngineeringJaipur 303903India Department of Physics Indian Institute of Technology-GuwahatiAssam 781039India Robotics and Mechatronics Research Center Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988South Korea

In this contribution,we reply to comments made by Tkach et *** our publication *** 2023;9:*** main interest of our work is to synthesize a lead-free material,SrTi_(2)O_(5)(STO),and then utilize it in the formation of composites and finally design the piezoelectric nanogenerator(peng)for self-powered sensor *** authors have observed the presence of piezoelectric voltage and current output from the *** authors humbly indicate that the peng devices were poled using a DC poling setup as conditions mentioned in *** 2023;9:609(Panda et al.,2023)[1].The doping of STO into the PDMS increased from 2% to 20%(in mass).In this process,the piezoelectric output of the peng device was observed to be highest for 15%(in mass)STO-PDMS ***,we agree with the comment raised by Tkach et al.,and further we have addressed the issues in a step-by-step response as follows.

关键词： Ferroelectric Lead-free Piezoelectric Polycrystalline

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Uncertainty analysis of flow rate measurement for multiphase flow using CFD

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Acta Mechanica Sinica 2015年第5期31卷 698-707页

作者： joon-hyung Kim Uk-Hee Jung Sung Kim joon-Yong Yoon Young-Seok Choi Department of Mechanical Design Engineering Hanyang University Thermal & Fluid System R&BD Group Korea Institute of Industrial Technology Energy System Engineering University of Science and Technology

The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow ***,it has excellent versatility and is being widely applied in many *** flow of a liquid containing air is a representative example of a multiphase flow and exhibits complex flow *** particular,the greater the gas volume fraction（GVF）,the more inhomogeneous the flow *** a result,using a venturi meter to measure the rate of a flow that has a high GVF generates an *** this study,the cause of the error occurred in measuring the flow rate for the multiphase flow when using the venturi meter for analysis by *** ensure the reliability of this study,the accuracy of the multiphase flow models for numerical analysis was verified through comparison between the calculated results of numerical analysis and the experimental *** a result,the Grace model,which is a multiphase flow model established by an experiment with water and air,was confirmed to have the highest ***,the characteristics of the internal flow Held about the multiphase flow analysis result generated by applying the Grace model were analyzed to find the cause of the uncertainty occurring when measuring the flow rate of the multiphase flow using the venturi meter.A phase separation phenomenon occurred due to a density difference of water and air inside the venturi,and flow inhomogeneity happened according to the flow velocity difference of each *** was confirmed that this flow inhomogeneity increased as the GVF increased due to the uncertainty of the flow measurement.

关键词： Multiphase flow Measurement Numerical analysis Venturi meter Gas volume fraction(GVF) Uncertainty Multiphase flow model Grace model

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Early gastric cancer presenting as a typical submucosal tumor cured by endoscopic submucosal dissection:A case report

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World Journal of Gastroenterology 2022年第25期28卷 2994-3000页

作者： joon Hyun Cho Si hyung Lee Division of Gastroenterology and Hepatology Department of Internal MedicineYeungnam University College of MedicineDaegu 42415South Korea

BACKGROUND Submucosal tumor(SMT)-like gastric cancer is rare,and almost all cases undergo curative surgical treatment because the submucosal layer is usually deeply invaded by tumor cells or because histopathologic types of SMT-like gastric cancer are undifferentiated or poorly *** report has been issued on an SMT-like gastric cancer cured by endoscopic resection alone or on changes in the endoscopic features of this type of tumor over several *** SUMMARY We describe an exceptional case of a 53-year-old male with a 1.5 cm-sized SMTlike lesion covered by normal-appearing mucosa discovered by esophagogastroduodenoscopy(EGD)at the gastric *** ultrasound(EUS)visualized a homogeneous,well-circumscribed hypoechogenic lesion arising from the second sonographic layer with associated subtle obliteration of the third sonographic *** endoscopic biopsy was negative for *** patient refused to undergo an invasive procedure and was subsequently lost to *** years after initial detection,EGD revealed the lesion had become markedly erythematous,and at 4 years after initial EGD it had increased in size to 1.8 cm and developed a central ulcer and a heterogeneous EUS ***,endoscopic submucosal dissection(ESD)was performed,and histopathologic examination revealed a moderately differentiated adenocarcinoma had minutely invaded the submucosal layer(invasion depth 169μm)but without lymphovascular invasion and with negative resection ***,no additional surgical treatment was *** has been followed for 4 years after ESD without any evidence of local or distant *** This report describes an extremely rare case of early gastric cancer presenting as SMT that was cured by ESD after a treatment delay of 4 years and the endoscopic changes that occurred during this *** report highlights the importance of considering the possibility of gastric cancer when SMT is encountered in clini

关键词： Subepithelial lesion Submucosal tumor Early gastric cancer Adenocarcinoma Endoscopic mucosal dissection Case report

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金鱼H 1组蛋白基因及其N端片段的克隆、表达及抗菌活性

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生物医学工程学杂志 2006年第3期23卷 609-614页

作者：魏泉德余新炳 Lim Ho Sung cha hyung joon 中山大学医学院病原生物学室广州510089 韩国蒲项工科大学化学工程系暨分子与生命科学部

用RT-PCR方法从金鱼体内成功分离得到编码H 1组蛋白的基因,基因登录号AY 184811。该基因与来源于大西洋鲑鱼的抗菌蛋白-H 1组蛋白有极高的同源性(78%)。将全长基因及其N端(2-38氨基酸)序列成功克隆于毕赤酵母分泌表达载体pP IC 9K并表达... 详细信息

用RT-PCR方法从金鱼体内成功分离得到编码H 1组蛋白的基因,基因登录号AY 184811。该基因与来源于大西洋鲑鱼的抗菌蛋白-H 1组蛋白有极高的同源性(78%)。将全长基因及其N端(2-38氨基酸)序列成功克隆于毕赤酵母分泌表达载体pP IC 9K并表达;表达产物初步检测有抗菌活性。结果表明,金鱼H 1组蛋白为一种新发现的抗菌蛋白,其N端来源肽(AEVAPAA SAPPAKAPKKK SAAKA KKAGPAVGDL IVKA)为抗微生物肽。金鱼H 1组蛋白及其来源肽在金鱼先天免疫防御中发挥作用。

关键词：抗微生物肽 H1组蛋白金鱼毕赤酵母 RT—PCR

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