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Pyunkang-hwan (Pyunkang-Tang) ameliorates air pollutant-induced inflammatory hypersecretion of airway mucus and bleomycin-induced pulmonary fibrosis in rats

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Journal of Traditional Chinese Medicine 2016年第5期36卷 663-670页

作者： hyo-seok seo Hyun Jae Lee Choong Jae Lee Department of Pharmacology School of Medicine Chungnam National University Department of Health Management Sahmyook University

OBJECTIVE: To investigate the effect of Pyunkanghwan(Pyunkang-tang) extract(PGT) on secretion of airway mucin in an experimental animal model involving hyperplasia of goblet cells and mucus hypersecretion, and to test its effects on bleomycin(BLM)-induced pulmonary fibrosis in ***: The protective activity of orally administered PGT was assessed in two rat pulmonary disease models. Effects on hypersecretion of pulmonary mucin in sulfur dioxide(SO_2)-induced bronchitis in rats were assessed by quantifying the amount of mucus secreted and examining histopathology in the tracheal epithelium. In a rat model for BLMinduced pulmonary fibrosis, toxicity to the pulmonary system was examined by measuring levels of malondialdehyde and hydroxyproline,indicators of lipid peroxides and collagen,respectively, in lung tissue 28 days post-BLM treatment. Serial sections of lung tissue were stained with Masson trichrome to visualize collagen deposition. Effects of PGT on collagen synthesis were also assessed in vitro, in a cell culture ***: PGT inhibited mucin secretion and normalized SO_2-induced increased muco- substances in goblet cells. In the BLM- induced model,PGT decreased the characteristic histopathological features of lung fibrosis and inhibited fibrotic lesions, as indicated by decreased hydroxyproline content. PGT also inhibited the BLM-induced increase in malondialdehyde levels, demonstrating its protective effect against lipid peroxidation in cell membranes of the lung. In MLg 2908 mouse lung fibroblast cells, PGT decreased transforming growth factor(TGF)-β-stimulated type I collagen ***: PGT can inhibit both hypersecretion of airway mucins and pulmonary fibrosis.

关键词： Pyunkang-hwan(Pyunkang-tang) Air pollutants Bleomycin Pulmonary fibrosis Airway mucin

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Aligned Ion Conduction Pathway of Polyrotaxane‑Based Electrolyte with Dispersed Hydrophobic Chains for Solid‑State Lithium–Oxygen Batteries

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Nano-Micro Letters 2025年第2期17卷 169-186页

作者： Bitgaram Kim Myeong‑Chang Sung Gwang‑Hee Lee Byoungjoon Hwang Sojung seo Ji‑Hun seo Dong‑Wan Kim Department of Materials Science and Engineering Korea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea School of Civil Environmental and Architectural EngineeringKorea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea Materials Science and Chemical Engineering Center Institute for Advanced Engineering(IAE)Yongin 17180Republic of Korea

A critical challenge hindering the practical application of lithium–oxygen batteries(LOBs)is the inevitable problems associated with liquid electrolytes,such as evaporation and safety *** study addresses these problems by proposing a modified polyrotaxane(mPR)-based solid polymer electrolyte(SPE)design that simultaneously mitigates solvent-related problems and improves ***-SPE exhibits high ion conductivity(2.8×10^(−3)S cm^(−1)at 25℃)through aligned ion conduction pathways and provides electrode protection ability through hydrophobic chain *** this mPR-SPE into solid-state LOBs resulted in stable potentials over 300 *** situ Raman spectroscopy reveals the presence of an LiO_(2)intermediate alongside Li_(2)O_(2)during oxygen *** situ X-ray diffraction confirm the ability of the SPE to hinder the permeation of oxygen and moisture,as demonstrated by the air permeability *** present study suggests that maintaining a low residual solvent while achieving high ionic conductivity is crucial for restricting the sub-reactions of solid-state LOBs.

关键词： Solid polymer electrolyte Lithium-oxygen batteries Polyrotaxane ion conductivity Hydrophobic chain

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Deep Drawing Process Using a Tractrix Die for Manufacturing Liners for a CNG High-Pressure Vessel(Type Ⅱ)

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Chinese Journal of Mechanical Engineering 2022年第1期35卷 132-143页

作者： Gun‑Young Park hyo‑seo Kwak hyo‑seong Jang Chul Kim School of Mechanical Engineering Pusan National UniversityPusan 46241South Korea Department of Mechanical Engineering Dong-eui UniversityPusan 47340Korea.

The liner of a CNG pressure vessel is manufactured by a DDI(deep drawing and ironing)process for the cylinder part,which is a continuous process that includes a drawing process to reduce the diameter of the billet and a subsequent ironing process to reduce the thickness of the billet.A tractrix die used in the 1^(st) deep drawing allows the blank to flow smoothly by decreasing the punch load and radial tensile stress occurring in the *** also increases the draw ratio compared to conventional dies,but it causes forming *** this study,a shape coefficient(S_(c))is proposed for the tractrix die using the blank diameter(D_(0)),inflow diameter of the workpiece(d_(i)),and inflow angle of the workpiece(θ)for design of the tractrix *** effects of the thickness and inflow angle of the workpiece on wrinkling and folding were investigated through ***,a discriminant is proposed for the relative radial stress(σ)generated during the deep drawing process using the tractirx die and used to predict *** on the results,the blank thickness,the draw ratio,and the inflow of the workpiece angle in the 1^(st) deep drawing process are suggested,and the number of operations in the DDI process was reduced from 6 to *** improves the productivity and reduces the manufacturing cost.

关键词： Tractrix die Deep drawing Wrinkling Folding LDR(Limit draw ratio) FEM

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Machine Vision Based Fish Cutting Point Prediction for Target Weight

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Computers, Materials & Continua 2023年第4期75卷 2247-2263页

作者： Yonghun Jang Yeong-seok seo Department of Computer Engineering Yeungnam UniversityGyeongsan38541Korea

Food processing companies pursue the distribution of ingredientsthat were packaged according to a certain weight. Particularly, foods like fishare highly demanded and supplied. However, despite the high quantity offish to be supplied, most seafood processing companies have yet to installautomation equipment. Such absence of automation equipment for seafoodprocessing incurs a considerable cost regarding labor force, economy, andtime. Moreover, workers responsible for fish processing are exposed to risksbecause fish processing tasks require the use of dangerous tools, such aspower saws or knives. To solve these problems observed in the fish processingfield, this study proposed a fish cutting point prediction method based onAI machine vision and target weight. The proposed method performs threedimensional(3D) modeling of a fish’s form based on image processing techniquesand partitioned random sample consensus (RANSAC) and extracts 3Dfeature information. Then, it generates a neural network model for predictingfish cutting points according to the target weight by performing machinelearning of the extracted 3D feature information and measured weight *** study allows for the direct cutting of fish based on cutting pointspredicted by the proposed method. Subsequently, we compared the measuredweight of the cut pieces with the target weight. The comparison result verifiedthat the proposed method showed a mean error rate of approximately 3%.

关键词： Machine vision fish cutting weight prediction artificial intelligence deep learning image processing

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Suggestion of advanced regression model on friction angle of fault gouge in South Korea

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Journal of Rock Mechanics and Geotechnical Engineering 2021年第6期13卷 1368-1379页

作者： seong-Woo Moon Hyun-seok Yun Yong-seok seo Department of Earth and Environmental Sciences Chungbuk National University1 Chungdae-roCheongju-siChungcheongbuk-do28644South Korea

Although friction characteristics of fault gouge are important to understand reactivation of fault,behavior of earthquake,and mechanism of slope failure,analysis results of fault gouge have low accuracy mostly than those of soils or rocks due to its high heterogeneity and low ***,to improve the accuracy of analysis results,we conducted simple regression analysis and structural equation model analysis and selected major influential factors of friction characteristics among many factors,and then we deduced advanced regression model with the highest coefficient of determination(R^(2)) via multiple regression *** most coefficients of determination in simple regression analysis are below0.3-0.4,coefficient of determination in multiple regression analysis is remarkably large as 0.657.

关键词： Fault gouge Friction angle Simple regression analysis Structural equation model analysis Multiple regression analysis

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Synthesis and spectral characteristics of La_2MoO_6:Ln^(3+) (Ln=Eu, Sm, Dy, Pr, Tb) polycrystals

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Journal of Rare Earths 2012年第9期30卷 866-870页

作者：孟凡桂张新民李焕 hyo Jin seo College of Materials Science and Engineering Central South University of Forestry and Technology Department of Physics Pukyong National University Busan 608-737 Republic of Korea

The novel phosphors of La2MoO6 activated with the trivalent rare earth Ln3＋（Ln=Eu, Sm, Dy, Pr, Tb） ions were synthesized by solid state reactions at high temperature in air atmosphere, and their phase impurities and luminescent properties were studied. The photolu- minescence （PL） excitation and emission spectra, and decay curves were employed to study their luminescence properties. The lifetimes of the characteristic emissions from Ln3＋ ions were in the order of millisecond except Pr3＋ ions. （LaEu1-x）2MoO6 was a promising phosphor for practical application and the optimum concentration was x=0.075. The concentration quenching mechanism of Eu3＋ was also discussed by theoretical fitting using Burshtein model.

关键词： photoluminescence phosphors La2MoO6 rare earths

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Thermal stability and spectroscopic properties of Ho^(3+) doped tellurite-borate glasses

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Journal of Rare Earths 2015年第9期33卷 939-945页

作者：杨艳民刘延洲蔡培庆 Ramzi Maalej hyo Jin seo College of Physics Science and Technology Hebei University Department of Physics Pukyong National University Laboratoire Géoressources Matériaux Environnement et Changements Globaux Faculty of Sciences of Sfax Sfax University

Ho3＋ ions doped tellurite-borate glass samples with varying compositions were prepared. The compositional dependence on phenomenological Judd-Ofelt parameters was compared in different kinds of rare earth ions doped tellurite-borate glasses. Two methods were used to obtain radiative transition probability of 517 level with the aim of assuring the fitting quality. The integral absorption cross-sections and line shapes corresponding to 518--.5G6 and 518---5I7 transition of Ho3＋ ions were investigated in tellurite-borate glasses. The obtained data indicated that the integral absorption cross-sections corresponding to 518-5G6 transition of Ho3＋ ions mainly depended on phenomenological Judd-Ofelt parameter, g22, because 518---5G6 transition belonged to hypersensitive transitions, which led to a larger gP2 value. The change of line shapes of absorption spectra corresponding to 518-5G6 and 518-517 transitions of Ho3＋ ions came from the lower energy regions, which could be attributed to the changed distribution of Stark levels and thermal population.

关键词： Ho3+ tellurite-borate glasses cross sections line shapes rare earths

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Effect of an Artificial Caudal Fin on the Performance of a Biomimetic Fish Robot Propelled by Piezoelectric Actuators

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Journal of Bionic Engineering 2007年第3期4卷 151-158页

作者： seok Heo Tedy Wiguna Hoon Cheol Park Nam seo Goo Artificial Muscle Research Center Konkuk UniversitySeoul 143-701Korea Department of Advanced Technology Fusion Konkuk UniversitySeoul 143-701Korea Department of Advanced Technology Fusion Artificial Muscle Research Center and Smart Robot CenterKonkuk UniversitySeoul 143-701Korea

This paper addresses the design of a biomimetic fish robot actuated by piezoeeramic actuators and the effect of artificial caudal fins on the fish robot＇s performance. The limited bending displacement produced by a lightweight piezocomposite actuator was amplified and transformed into a large tail beat motion by means of a linkage system. Caudal fins that mimic the shape of a mackerel fin were fabricated for the purpose of examining the effect of caudal fm characteristics on thrust production at an operating frequency range. The thickness distribution of a real mackerel＇s fin was measured and used to design artificial caudal fins. The thrust performance of the biomimetic fish robot propelled by fins of various thicknesses was examined in terms of the Strouhal number, the Froude number, the Reynolds number, and the power consumption. For the same fm area and aspect ratio, an artificial caudal fin with a distributed thickness shows the best forward speed and the least power consumption.

关键词： LIPCA biomimetic fish robot caudal fro Strouhal number Froude number Reynolds number

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Relationship of meteorological factors and air pollutants with medical care utilization for gastroesophageal reflux disease in urban area

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World Journal of Gastroenterology 2020年第39期26卷 6074-6086页

作者： Ho seok seo Jinwook Hong Jaehun Jung Division of Gastrointestinal Surgery Department of SurgerySeoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Artificial Intelligence and Big-Data Convergence Center Gil Medical CenterGachon University College of Medicine and ScienceIncheon 21565South Korea Department of Preventive Medicine Gachon University College of MedicineIncheon 21565South Korea

BACKGROUND Gastroesophageal reflux disease(GERD)is a highly prevalent disease of the upper gastrointestinal tract,and it is associated with environmental and lifestyle *** to an increasing interest in the environment,several groups are studying the effects of meteorological factors and air pollutants(MFAPs)on disease *** To identify MFAPs effect on GERD-related medical *** Data on GERD-related medical utilization from 2002 to 2017 were obtained from the National Health Insurance Service of Korea,while those on MFAPs were obtained from eight metropolitan areas and *** total,20071900 instances of GERD-related medical utilizations were identified,and 200000 MFAPs were randomly selected from the eight metropolitan *** were analyzed using a multivariable generalized additive Poisson regression model to control for time trends,seasonality,and day of the *** Five MFAPs were selected for the prediction ***-related medical utilization increased with the levels of particulate matter with a diameter≤2.5μm(PM2.5)and carbon monoxide(CO).S-shaped and inverted U-shaped changes were observed in average temperature and air pollutants,*** time lag of each variable was significant around nine days after *** Using five MFAPs,the final model significantly predicted GERD-related medical *** particular,PM2.5 and CO were identified as risk or aggravating factors for GERD.

关键词： Gastroesophageal reflux disease Air pollution Meteorological factor Particulate matter Carbon monoxide

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Evaluation of vibration and sound quality according to battery voltage change while moving a power seat in an automobile forward or backward

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Journal of Central South University 2014年第10期21卷 3844-3849页

作者： Kang-seok seo Doo-seuk Choi Key-sun Kim Department of Mechanical Engineering Graduate School Kongju National University Division of Automotive and Mechanical Engineering Kongju National University

The changes in vibration, sound, and sound quality with changes in the driving voltage of a power seat motor from 12.5 to 14.5 V were measured and analyzed, which was used in real vehicles. BSR(buzz, squeak, rattle), which occurs for the power seat mechanism during sliding operation, was also evaluated. In addition, the results were expressed in terms of sound quality metrics, which measure the RPM change and sound level versus voltage to analyze their statistical correlation. Furthermore, vibration measurement and analysis were conducted simultaneously to determine the noisiest conditions and the source of the noise. The changes in RPM and voltage of a motor, in addition to vibration and noise, were measured at the same time to determine how noise, RPM, and voltage are interrelated.

关键词： seat vibration seat noise sound quality voltage buzz squeak and rattle(BSR)

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