Relationship of meteorological factors and air pollutants with medical care utilization for gastroesophageal reflux disease in urban area

作     者：Ho Seok Seo Jinwook Hong Jaehun Jung 

作者机构：Division of Gastrointestinal SurgeryDepartment of SurgerySeoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Artificial Intelligence and Big-Data Convergence CenterGil Medical CenterGachon University College of Medicine and ScienceIncheon 21565South Korea Department of Preventive MedicineGachon University College of MedicineIncheon 21565South Korea 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2020年第26卷第39期

页      面：6074-6086页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Gachon University Gil Medical Center No.FRD2018-17 and No.FRD2019-11 

主　　题：Gastroesophageal reflux disease Air pollution Meteorological factor Particulate matter Carbon monoxide 

摘      要：BACKGROUND Gastroesophageal reflux disease(GERD)is a highly prevalent disease of the upper gastrointestinal tract,and it is associated with environmental and lifestyle *** to an increasing interest in the environment,several groups are studying the effects of meteorological factors and air pollutants(MFAPs)on disease *** To identify MFAPs effect on GERD-related medical *** Data on GERD-related medical utilization from 2002 to 2017 were obtained from the National Health Insurance Service of Korea,while those on MFAPs were obtained from eight metropolitan areas and *** total,20071900 instances of GERD-related medical utilizations were identified,and 200000 MFAPs were randomly selected from the eight metropolitan *** were analyzed using a multivariable generalized additive Poisson regression model to control for time trends,seasonality,and day of the *** Five MFAPs were selected for the prediction ***-related medical utilization increased with the levels of particulate matter with a diameter≤2.5μm(PM2.5)and carbon monoxide(CO).S-shaped and inverted U-shaped changes were observed in average temperature and air pollutants,*** time lag of each variable was significant around nine days after *** Using five MFAPs,the final model significantly predicted GERD-related medical *** particular,PM2.5 and CO were identified as risk or aggravating factors for GERD.