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Perspectives of pluripotent stem cells in livestock

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World Journal of Stem Cells 2021年第1期13卷 1-29页

作者： Dharmendra Kumar Thirumala R Talluri Naresh L Selokar iqbal hyder Wilfried A Ku Animal Physiology and Reproduction Division ICARCentral Institute for Research on BuffaloesHisar 125001India Equine Production Campus ICAR-National Research Centre on EquinesBikaner 334001India Department of Physiology NTR College of Veterinary ScienceGannavaram 521102India Department of Biotechnology Friedrich-Loeffler-InstituteFederal Institute of Animal HealthNeustadt 31535Germany

The recent progress in derivation of pluripotent stem cells(PSCs)from farm animals opens new approaches not only for reproduction,genetic engineering,treatment and conservation of these species,but also for screening novel drugs for their efficacy and toxicity,and modelling of human *** attempts to derive PSCs from the inner cell mass of blastocyst stages in farm animals were largely unsuccessful as either the cells survived for only a few passages,or lost their cellular potency;indicating that the protocols which allowed the derivation of murine or human embryonic stem(ES)cells were not sufficient to support the maintenance of ES cells from farm *** scenario changed by the innovation of induced pluripotency and by the development of the 3 inhibitor culture conditions to support naïve pluripotency in ES cells from livestock ***,the long-term culture of livestock PSCs while maintaining the full pluripotency is still challenging,and requires further ***,we review the current achievements in the derivation of PSCs from farm animals,and discuss the potential application areas.

关键词： Livestock Cellular reprogramming Chimera Cell-therapy Ontogenesis Pluripotency

Prediabetes and atrial fibrillation risk stratification,phenotyping,and possible reversal to normoglycemia

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World Journal of Diabetes 2025年第1期16卷 7-11页

作者： hyder O Mirghani Department of Internal Medicine University of TabukTabuk 51941TabukSaudi Arabia

Patients admitted with prediabetes and atrial fibrillation are at high risk for major adverse cardiac or cerebrovascular events independent of confounding *** shared pathophysiology between these three serious but common diseases and their association with atherosclerotic cardiovascular risk factors establish a vicious circle culminating in high *** of that,it is of paramount importance to perform risk stratification of patients with prediabetes to define phenotypes that benefit from various ***,stress hyperglycemia assessment of hospitalized patients and consensus on the definition of prediabetes is *** roles lifestyle and metformin play in prediabetes are well ***,the role of glucagon-like peptide agonists and metabolic surgery is less *** is considered an intermediate between normoglycemia and diabetes along the blood glucose *** billion people are expected to suffer from prediabetes by the year ***,realworld randomized controlled trials to assess major adverse cardiac or cerebrovascular event risk reduction and reversal/prevention of type 2 diabetes among patients are needed to determine the proper interventions.

关键词： Major adverse cardiac or cerebrovascular event Prediabetes Risk stratification Phenotype Stress hyperglycemia Reversal to normoglycemia

Abundant solutions of Wick-type stochastic fractional 2D KdV equations

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Chinese Physics B 2014年第6期23卷 97-103页

作者： Hossam A.Ghany Abd-Allah hyder Department of Mathematics Faculty of Science Taif University Department of Mathematics Helwan University Department of Engineering Physics and Mathematics Faculty of Engineering Al-Azhar University

A modified fractional sub-equation method is applied to Wick-type stochastic fractional two-dimensional （2D） KdV equations. With the help of a Hermit transform, we obtain a new set of exact stochastic solutions to Wick-type stochastic fractional 2D KdV equations in the white noise space. These solutions include exponential decay wave solutions, soliton wave solutions, and periodic wave solutions. Two examples are explicitly given to illustrate our approach.

关键词： 2D KdV equations fractional calculus white noise Hermite transform

Exact solutions of stochastic fractional Korteweg de–Vries equation with conformable derivatives

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Chinese Physics B 2020年第3期29卷 62-69页

作者： Hossam A.Ghany Abd-Allah hyder M Zakarya King Khalid University College of ScienceDepartment of MathematicsP.O.Box 900461413AbhaSaudi Arabia Department of Engineering Mathematics and Physics Faculty of EngineeringAl-Azhar University11371CairoEgypt Department of Mathematics Helwan UniversitySawah Street(11282)CairoEgypt Department of Mathematics Faculty of ScienceAl-Azhar University71524AssiutEgypt

We deal with the Wick-type stochastic fractional Korteweg de–Vries(KdV) equation with conformable *** the aid of the Exp-function method, white noise theory, and Hermite transform, we produce a novel set of exact soliton and periodic wave solutions to the fractional KdV equation with conformable derivatives. With the help of inverse Hermite transform, we get stochastic soliton and periodic wave solutions of the Wick-type stochastic fractional KdV equation with conformable derivatives. Eventually, by an application example, we show how the stochastic solutions can be given as Brownian motion functional solutions.

关键词： Korteweg de–Vries(KdV)equation conformable derivative stochastic Brownian motion Expfunction method

Glucagon-like peptide-1 agonists:Role of the gut in hypoglycemia unawareness,and the rationale in type 1 diabetes

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World Journal of Diabetes 2024年第11期15卷 2167-2172页

作者： hyder O Mirghani Internal Medicine University of TabukTabuk 51941TabukSaudi Arabia

Type 1 diabetes is increasing and the majority of patients have poor glycemic *** advanced technology and nanoparticle use have greatly enhanced insulin delivery and glucose monitoring,weight gain and hypoglycemia remain major challenges and a constant source of concern for patients with type 1 *** 1 diabetes shares some pathophysiology with type 2 diabetes,and an overlap has been *** above observation created great interest in glucagon-like peptide-1 receptor agonists(GLP-1)as adjuvants for type 1 *** trials confirmed the positive influence of GLP-1 agonists onβcell ***,hypoglycemia unawareness and dysregulated glucagon response have been previously reported in patients with recurrent hypoglycemia using GLP-1 *** et al found that the source of glucagon dysregulation due to GLP-1 agonists resides in the *** explanations could be gut nervous system dysregulation or gut microbiota *** review evaluates the potential of GLP-1 agonists in managing type 1 diabetes,particularly focusing on their impact on glycemic control,weight management,and glucagon *** provide a broader insight into the problem of type 1 diabetes mellitus management in the light of recent findings and provide future research directions.

关键词： Glucagon-like peptide-1 receptor agonists Glucagon response Hypoglycemia unawareness Gut Type 1 diabetes

Effect of dates on blood glucose and lipid profile among patients with type 2 diabetes

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World Journal of Diabetes 2024年第6期15卷 1079-1085页

作者： hyder Osman Mirghani Internal Medicine University of TabukSaudi ArabiaTabuk 51941TabukSaudi Arabia

Poor fruit and vegetable consumption is one of the 10 major risk factors for *** is a misconception regarding the consumption of dates among patients with *** manuscript assessed the effects of date consumption on fasting and postprandial blood glucose,glycated hemoglobin,total cholesterol,triglycerides,low-density lipoproteins,high-density lipoproteins,and microbial *** literature databases were searched for relevant *** the 595 studies retrieved,24 assessed the effects of dates on glycemic control and ***,the evidence suggests that dates have a lowering effect on blood *** reduce total cholesterol and triglyceride levels and increase high-density lipoprotein *** also promote the abundance of beneficial gut ***,patients with diabetes and dyslipidemia can consume dates to reduce their blood glucose,cholesterol,and triglycerides.

关键词： Dates Lipid profile Blood glucose Diabetes mellitus Microbial contamination

Fractional Optimal Control of Navier-Stokes Equations

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Computers, Materials & Continua 2020年第8期64卷 859-870页

作者： Abd-Allah hyder M.El-Badawy King Khalid University College of ScienceDepartment of MathematicsP.O.Box 900461413AbhaSaudi Arabia Department of Engineering Mathematics and Physics Faculty of EngineeringAl-Azhar UniversityCairo11371Egypt Mathematics Department Al-Azhar UniversityCairoEgypt

In this paper,the non-stationary incompressible fluid flows governed by the Navier-Stokes equations are studied in a bounded *** study focuses on the time-fractional Navier-Stokes equations in the optimal control subject,where the control is distributed within the domain and the time-fractional derivative is proposed as Riemann-Liouville *** addition,the control object is to minimize the quadratic cost *** using the Lax-Milgram lemma with the assistance of the fixed-point theorem,we demonstrate the existence and uniqueness of the weak solution to this ***,for a quadratic cost functional subject to the time-fractional Navier-Stokes equations,we prove the existence and uniqueness of optimal ***,via the variational inequality upon introducing the adjoint linearized system,some inequalities and identities are given to guarantee the first-order necessary optimality conditions.A direct consequence of the results obtained here is that when a→1,the obtained results are valid for the classical optimal control of systems governed by the Navier-Stokes equations.

关键词： Optimal control lax-milgram lemma fixed point theorem navier-stokes equations

Physicochemical Properties of Amino Acids in Aqueous Caffeine Solution at 25, 30, 35 and 40℃

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Chinese Journal of Chemistry 2006年第11期24卷 1547-1553页

作者： ALI, A. SABIR, S. SHAHJAHAN hyder, S. Department of Chemistry Jamia Millia Islamia (Central University) New Delhi-11 0025 India

Density, viscosity, and refractive index, for glycine, DL-alanine, L-serine and DL-valine have been determined in aqueous solution of 0.05 mol/kg caffeine as a function of amino acid （AA） concentration at 25, 30, 35, and 40 ℃ The density data have been used to compute apparent molar volume. The partial molar volume （limiting apparent molar volume） was obtained by applying the Masson＇s equation. The viscosity data have been analyzed by means of Jones-Dole equation. The values of Falkenhagen coefficient and Jones-Dole coefficient thus obtained are used to interpret the solute-solute and solute-solvent interactions, respectively. Hydration number was also computed. The transition-state theory was applied to obtain the activation parameters of viscous flow, i.e., free energy of activation per mole of solvent, and solute. The enthalpy and entropy of activation of viscous flow were computed for the system. Refractive index was used to calculate molar refractivity of the mixtures. The results have been interpreted in the light of various interactions occurring between the components of the mixtures under applied experimental conditions.

关键词： amino acid caffeine Falkenhagen coefficient Jones-Dole coefficient molecular interactions

Maximum sustainable yield of Greater lizardfish Saurida tumbil fishery in Pakistan using the CEDA and ASPIC packages

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Acta Oceanologica Sinica 2015年第2期34卷 68-73页

作者： KALHORO Muhsan Ali LIU Qun MEMON Khadim Hussain WARYANI Baradi SOOMRO Shamsher hyder College of Fisheries Ocean University of China Marine Fisheries Department Fish Harbor West Wharf Karachi Department of Freshwater Biology and Fisheries University of Sindh

The catch and effort data analysis（CEDA） and ASPIC（a stock assessment production model incorporating covariates） computer software packages were used to estimate the maximum sustainable yield（MSY） from the catch and effort data of Greater lizardfish Saurida tumbil fishery of Pakistan from 1986 to 2009. In CEDA three surplus production models of Fox, Schaefer and Pella-Tomlinson were used. Here initial proportion（IP） of 0.5 was used because the starting catch was roughly 50% of the maximum catch. With IP = 0.5, the estimated MSY from Fox model were 20.59 mt and 38.16 mt for normal and log-normal error assumptions, while the MSY from Schaefer and Pella-Tomlinson were 60.40, 60.40 and 60.40 mt, for normal, log-normal and gamma error assumptions respectively. The MSY values from Schaefer and Pella-Tomlinson models of three error assumptions were the same. The R2 values from those three models were above 0.6. When IP = 0.5, the MSY values estimated from ASPIC from Fox were 132 mt, and from logistic model were 69.4 mt, with R2 value above 0.8. Therefore we suggest the MSY of S. tumbil fishery from Pakistan to be 60–70 mt, which is higher than the latest catch, thus we would recommend that the fishing efforts for this fishery may be kept at the current level.

关键词： Pakistan Sauridatumbil ASPIC CEDA MSY