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Comparison of Treatment Efficacy of Different Number of Botulinum Toxin Type A Injection Sites for Crow's Feet Lines: A Single-Center Retrospective Clinical Study in Vietnam

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International Journal of Dermatology and Venereology 2024年第3期7卷 131-136页

作者： Nguyen Quang M. le Thi M. Duong Phuc H. vu Thai H. le Huu D. Department of Stem Cell Research and Application National Hospital of Dermatology and Venereology Hanoi 100000 Viet Nam Department of Healthcare Activity Direction National Hospital of Dermatology and Venereology Hanoi 100000 Viet Nam Department of Dermatology Hanoi Medical University Hanoi 100000 Viet Nam

Objective: Botulinum toxin type A is frequently used to treat crow's feet lines. However, the optimal dose and injection sites are still controversial. The objective of this study was to compare the efficacy of different botulinum toxin type A injection patterns for the treatment of crow's feet. Methods: This single-center, retrospective, clinical study was conducted at the National Hospital of Dermatology and Venereology from July 2020 to December 2020. Data on 60 patients with crow's feet were collected and divided into 2 groups (3- or 4-point intramuscular injection) according to the intramuscular injection technique the patients received. The treatment efficacy was assessed based on the changes in the Crow's Feet Grading Scale score at 1, 4, and 16 weeks after treatment. Repeated measures analysis of variance was used for the assessment of changes in scores over time between the two groups. Results: After treatment, the average Crow's Feet Grading Scale score was significantly decreased compared with the pretreatment score at all timepoints (1, 4, and 16 weeks) in both states (dynamic: For 3-point intramuscular injection technique, 1 week: 1.90 ± 0.71 vs. 2.97 ± 0.56; 4 weeks: 1.87 ± 0.68 vs. 2.97 ± 0.56; 16 weeks: 2.60 ± 0.67 vs. 2.97 ± 0.56. For 4-point intramuscular injection technique, 1 week: 1.73 ± 0.83 vs. 3.03 ± 0.49; 4 weeks: 1.73 ± 0.74 vs. 3.03 ± 0.49; 16 weeks: 2.57 ± 0.68 vs. 3.03 ± 0.49, all P < 0.001. and static: For 3-point intramuscular injection technique, 1 week: 1.20 ± 0.89 vs. 2.20 ± 0.85; 4 weeks: 1.20 ± 0.89 vs. 2.20 ± 0.85; 16 weeks: 1.87 ± 0.97 vs. 2.20 ± 0.85; For 4-point intramuscular injection technique, 1 week: 1.50 ± 0.86 vs. 2.30 ± 0.84; 4 weeks: 1.33 ± 0.84 vs. 2.30 ± 0.84; 16 weeks: 1.87 ± 0.97 vs. 2.30 ± 0.84. All P < 0.001). The average subjective patient-rated satisfaction scores after treatment were significantly higher in the 4-point injection group than in the 3-point injection group (P = 0.028). The adverse events were pos

关键词： botulinum toxin type A crow's feet lines dose injection site

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Generating highly active oxide-phosphide heterostructure through interfacial engineering to break the energy scaling relation toward urea-assisted natural seawater electrolysis

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Journal of Energy Chemistry 2024年第10期97卷 687-699页

作者： Ngoc Quang Tran Nam Hoang vu Jianmin Yu Khanh Vy Pham Nguyen Thuy Tien Nguyen Tran Thuy-Kieu Truong Lishan Peng Thi Anh le Yoshiyuki Kawazoe Center for Innovative Materials and Architectures Vietnam National University Faculty of Materials Science and Technology University of Science Key Laboratory of Rare Earths Ganjiang Innovation Academy Chinese Academy of Sciences Department of Mechanical Engineering Hanbat National University (HBNU) School of Chemical Engineering-Hanoi University of Science and Technology New Industry Creation Hatchery Center Tohoku University

Urea-assisted natural seawater electrolysis is an emerging technology that is effective for grid-scale carbon-neutral hydrogen mass production yet *** scaling relations is an effective strategy to break through the bottleneck of natural seawater ***,by DFT calculation,we demonstrated that the interface boundaries between Ni2P and MoO2play an essential role in the selfrelaxation of the Ni-O interfacial bond,effectively modulating a coordination number of intermediates to control independently their adsorption-free energy,thus circumventing the adsorption-energy scaling *** this conceptual model,a well-defined 3D F-doped Ni2P-MoO2heterostructure microrod array was rationally designed via an interfacial engineering strategy toward urea-assisted natural seawater *** a result,the F-Ni2P-MoO2exhibits eminently active and durable bifunctional catalysts for both HER and OER in acid,alkaline,and alkaline sea water-based *** in-situ analysis,we found that a thin amorphous layer of NiOOH,which is evolved from the Ni2P during anodic reaction,is real catalytic active sites for the OER and UOR ***,such electrode-assembled urea-assisted natural seawater electrolyzer requires low voltages of 1.29 and 1.75 V to drive 10 and600 mA cm-2and demonstrates superior durability by operating continuously for 100 h at 100 mA cm-2,beyond commercial Pt/C || RuO2and most previous reports.

关键词： Break scaling relationships Doping Interfacial engineering Natural seawater splitting Urea electrolysis

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Clinical validation of the early embryo viability assessment system: Analysis for the blastocyst morphology and pregnancy outcomes

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Asian pacific Journal of Reproduction 2024年第5期13卷 219-227页

作者： vu D Hop An M Cuong Phi T T Anh Nguyen T L Huong le Hoang Nguyen V Hanh Assisted Reproductive Technology Centre Tam Anh General HospitalHanoiVietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoiVietnam

Objective:To determine the relationship between the early embryo viability assessment(EEVA)and blastocyst morphological parameters and pregnancy ***:This retrospective cohort study was conducted on 291 intracytoplasmic sperm injection cycles including 2522 embryos with indications of prolonging embryo culture to the blastocyst stage in the Genea embryo review incubator,and 511 single vitrified-warmed blastocyst transfer cycles from January 2020 to June *** EEVA system produced an EEVA score from E1(best)to E5(worse)for the potential of blastocyst *** morphology was *** association between the EEVA score and each type of blastocyst morphology,implantation rate,clinical pregnancy,and ongoing pregnancy were assessed using generalized estimating ***:The inner cell mass A(ICM A),trophectoderm A(TE A),blastocoele expansion degree of 3,4,5,6,7 rates were higher with lower the EEVA *** adjusted odd ratio(aOR)(E5 vs E1)was 0.3 for ICM A,0.174 for TE A and 0.210 for BL3,4,5,6,7(all P<0.001),suggesting a significant association between lower EEVA scores and improved embryo *** implantation,clinical pregnancy,and ongoing pregnancy rate were also higher with lower the EEVA *** aOR of E5 vs E1 was 0.245 for implantation,0.185 for clinical pregnancy and 0.200 for ongoing pregnancy rate(P<0.001).Conclusions:There were associations between blastocyst morphology,pregnancy outcome and EEVA *** good blastocyst morphology and pregnancy outcomes are higher with lower the EEVA score.

关键词： Automated embryo assessment Blastocyst Early embryo viability assessment Genea embryo review incubator

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Modelling the viscoplastic behaviour of Callovo-Oxfordian claystone with consideration of damage effect

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第1期16卷 303-316页

作者： Hao Wang Yu-Jun Cui Minh Ngoc vu Jean Talandier Ecole des Ponts ParisTech Laboratoire Navier/CERMES6 et 8 avenue Blaise PascalMarne La Vallée cedex 277455France Andra R&D DepartmentChâtenay-Malabry92290France

In order to evaluate the performance of deep geological disposal of radioactive waste,an underground research laboratory(URL)was constructed by Andra in the Callovo-Oxfordian(COx)claystone formation at the Meuse/Haute-Marne(MHM).The construction of URL induced the excavation damage of host formations,and the ventilation in the galleries desaturated the host formation close to the gallery ***,it is expected that the mechanical behaviour of COx claystone is *** study presents a constitutive model developed to describe the viscoplastic behaviour of unsaturated and damaged COx *** this model,the unsaturation effect is considered by adopting the Bishop effective stress and the van Genuchten(VG)water retention *** terms of the viscoplastic behaviour,the nonstationary flow surface(NSFS)theory for unsaturated soils is used with consideration of the coupled effects of strain rate and suction on the yield stress.A progressive hardening law is ***,a non-associated flow rule is used,which is similar to that in Barcelona basic model(BBM).In addition,to describe the damage effect induced by suction change and viscoplastic loading,a damage function is defined based on the crack volume *** damage function contains two variables:unsaturated effective stress and viscoplastic volumetric strain,with the related parameters determined based on the mercury intrusion porosimetry(MIP)*** the model validation,different tests on COx claystone under different loading paths are *** between experimental and simulated results indicated that the present model is able to well describe the viscoplastic behaviour of damaged COx claystone,including swelling/shrinkage,triaxial extension and compression,and triaxial creep.

关键词： Callovo-Oxfordian(COx)claystone Excavation damage Time-dependent behaviour Suction Viscoplastic model

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Optimal Scheduling of Multiple Rail Cranes in Rail Stations with Interference Crane Areas

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Intelligent Automation & Soft Computing 2024年第1期39卷 15-31页

作者： Nguyen vu Anh Duy Nguyen le Thai Nguyen Huu Tho Faculty of Engineering and Technology Nguyen Tat Thanh UniversityHo Chi Minh City700000Vietnam

In this paper,we consider a multi-crane scheduling problem in rail stations because their operations directly influence the throughput of the rail *** particular,the job is not only assigned to cranes but also the job sequencing is implemented for each crane to minimize the makespan of cranes.A dual cycle of cranes is used to minimize the number of working cycles of *** rail crane scheduling problems in this study are based on the movement of *** consider not only the gantry moves,but also the trolley moves as well as the rehandle cases are also included.A mathematical model of multi-crane scheduling is *** traditional and parallel simulated annealing(SA)are adapted to determine the optimal scheduling *** examples are conducted to evaluate the applicability of the proposed *** of the proposed parallel SA is done by comparing it to existing previous *** of numerical computation highlighted that the parallel SA algorithm outperformed the SA and gave better solutions than other considered algorithms.

关键词： Multi-crane scheduling logistics containers makespan rail stations

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Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients

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World Journal of Clinical Oncology 2024年第2期15卷 290-301页

作者： Nhu Thi Hanh vu Huy Minh le Diem Thi-Ngoc Vo Hoang Anh vu Nhan Quang le Dung Dang Quy Ho Duc Trong Quach Department of Internal Medicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam GI Endoscopy Department University Medical Center at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Histology-Embryology and Pathology University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Center for Molecular Biomedicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Endoscopy Cho Ray HospitalHo Chi Minh 700000Viet Nam

BACKGROUND Sessile serrated lesions(SSLs)are considered precancerous colorectal lesions that should be detected and removed to prevent colorectal *** studies in Vietnam mainly investigated the adenoma pathway,with limited data on the serrated *** To evaluate the prevalence,risk factors,and BRAF mutations of SSLs in the Vietnamese *** This is a cross-sectional study conducted on patients with lower gastrointestinal symptoms who underwent colonoscopy at a tertiary hospital in *** were diagnosed on histopathology according to the 2019 World Health Organi-zation *** mutation analysis was performed using the Sanger DNA sequencing *** multivariate logistic regression model was used to determine SSL-associated *** There were 2489 patients,with a mean age of 52.1±13.1 and a female-to-male ratio of 1:*** prevalence of SSLs was 4.2%[95%confidence interval(CI):3.5-5.1].In the multivariate analysis,factors significantly associated with SSLs were age≥40[odds ratio(OR):3.303;95%CI:1.607-6.790],male sex(OR:2.032;95%CI:1.204-3.429),diabetes mellitus(OR:2.721;95%CI:1.551-4.772),and hypertension(OR:1.650,95%CI:1.045-2.605).The rate of BRAF mutations in SSLs was 35.5%.CONCLUSION The prevalence of SSLs was 4.2%.BRAF mutations were present in one-third of *** risk factors for SSLs included age≥40,male sex,diabetes mellitus,and hypertension.

关键词： Colorectal cancer Sessile serrated lesion BRAF mutation Risk factors Diabetes mellitus Hypertension

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Photocatalytic degradation of antibiotic sulfamethizole by visible light activated perovskite LaZnO_(3)

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Journal of Environmental Sciences 2024年第10期144卷 212-224页

作者： Bui The Huy XCuong Nguyen vu Khac Hoang Bui Nguyen Ngoc Tri Iqra Rabani Nhu Hoa Thi Tran Quang Viet Ly Hai Bang Truong Major of Biomedical Engineering Division of Smart HealthcareCollege of Information Technology and ConvergencePukyong National UniversityBusan 48513Korea Center for Advanced Chemistry Institute of Research and DevelopmentDuy Tan UniversityDa Nang 550000Viet Nam Faculty of Environmental and Chemical Engineering Duy Tan UniversityDa Nang 550000Viet Nam Department of Environment and Energy Sejong UniversitySeoul 05006Korea Lab of Computational Chemistry and Modelling Department of ChemistryFaculty of Natural SciencesQuy Nhon UniversityQuy NhonViet Nam Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Korea Faculty of Materials Science and Technology University of ScienceHo Chi Minh City 700000Viet Nam Vietnam National University Ho Chi Minh City 700000Viet Nam Department of Environmental Engineering Seoul National University of Science and TechnologySeoul 01811Korea Optical Materials Research Group Science and Technology Advanced InstituteVan Lang UniversityHo Chi Minh CityViet Nam Faculty of Applied Technology School of TechnologyVan Lang UniversityHo Chi Minh CityViet Nam

In thiswork,the perovskite LaZnO_(3) was synthesized via sol-gel method and applied for photocatalytic treatment of sulfamethizole(SMZ)antibiotics under visible light *** was almost completely degraded(99.2%±0.3%)within 4 hr by photocatalyst LaZnO3 at the optimal dosage of 1.1 g/L,with amineralization proportion of 58.7%±0.4%.The efficient performance of LaZnO_(3) can be attributed to itswide-range light absorption and the appropriate energy band edge levels,which facilitate the formation of active agents such as·O_(2)^(−),h^(+),and·*** integration of RP-HPLC/Q-TOF-MS and DFT-based computational techniques revealed three degradation pathways of SMZ,which were initiated by the deamination reaction at the aniline ring,the breakdown of the sulfonamidemoieties,and a process known as Smile-type rearrangement and SO2 *** toxicity of SMZ and the intermediateswere analyzed by quantitative structure activity relationship(QSAR),indicating the effectiveness of LaZnO_(3)-based photocatalysis in preventing secondary pollution of the intermediates to the ecosystem during the degradation *** visible-light-activated photocatalyst LaZnO_(3) exhibited efficient performance in the occurrence of inorganic anions and maintained high durability across multiple recycling tests,making it a promising candidate for practical antibiotic treatment.

关键词： Perovskite Antibiotics Photocatalysis Density functional theory Toxicity

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A Study on Optimizing the Double-Spine Type Flow Path Design for the Overhead Transportation System Using Tabu Search Algorithm

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Intelligent Automation & Soft Computing 2024年第2期39卷 255-279页

作者： Nguyen Huu Loc Khuu Thuy Duy Truong Quoc Dien le Tran Thanh Cong vu Hoa Binh Tran Tuong Quan Vo Department of Mechatronics Faculty of Mechanical EngineeringHo Chi Minh City University of Technology(HCMUT)Ho Chi Minh CityVietnam Bach Khoa Research Center for Manufacturing Engineering Ho Chi Minh City University of Technology(HCMUT)Ho Chi Minh CityVietnam VietnamNational University Ho ChiMinh City Ho ChiMinh CityVietnam

Optimizing Flow Path Design(FPD)is a popular research area in transportation system design,but its application to Overhead Transportation Systems(OTSs)has been *** study focuses on optimizing a double-spine flow path design for OTSs with 10 stations by minimizing the total travel distance for both loaded and empty *** employ transportation methods,specifically the North-West Corner and Stepping-Stone methods,to determine empty vehicle travel ***,the Tabu Search(TS)algorithm is applied to branch the 10 stations into two main layout *** results obtained from our proposed method demonstrate a reduction in the objective function value compared to the initial feasible ***,we explore howchanges in the parameters of the TS algorithm affect the optimal *** validate the feasibility of our approach by comparing it with relevant literature and conducting additional tests on layouts with 20 and 30 stations.

关键词： Overhead transportation systems tabu search double-spine layout transportationmethod empty travel flow path design

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Organoid intelligence:Integration of organoid technology and artificial intelligence in the new era of in vitro models

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Medicine in Novel Technology and Devices 2024年第1期21卷 39-44页

作者： Huaiyu Shi Andrew Kowalczewski Danny vu Xiyuan Liu Asif Salekin Huaxiao Yang Zhen Ma Department of Biomedical&Chemical Engineering Syracuse UniversitySyracuseNYUSA BioInspired Institute for Material and Living Systems Syracuse UniversitySyracuseNYUSA Department of Mechanical&Aerospace Engineering Syracuse UniversitySyracuseNYUSA Department of Electrical Engineering&Computer Science Syracuse UniversitySyracuseNYUSA Department of Biomedical Engineering University of North TexasDentonTXUSA

Organoid Intelligence ushers in a new era by seamlessly integrating cutting-edge organoid technology with the power of artificial ***,three-dimensional miniature organ-like structures cultivated from stem cells,offer an unparalleled opportunity to simulate complex human organ systems in *** the convergence of organoid technology and AI,researchers gain the means to accelerate discoveries and insights across various *** intelligence algorithms enable the comprehensive analysis of intricate organoid behaviors,intricate cellular interactions,and dynamic responses to *** synergy empowers the development of predictive models,precise disease simulations,and personalized medicine approaches,revolutionizing our understanding of human development,disease mechanisms,and therapeutic *** Intelligence holds the promise of reshaping how we perceive in vitro modeling,propelling us toward a future where these advanced systems play a pivotal role in biomedical research and drug development.

关键词： Organoids Machinelearning Deep learning Artificial intelligence Stem cells

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Comparison of Treatment Efficacy of Different Number of Botulinum Toxin Type A Injection Sites for Crow’s Feet Lines: A Single-Center Retrospective Clinical Study in Vietnam

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International Journal of Dermatology And Venereology 2024年第03期

作者： Quang Minh Nguyen le Thi Mai Phuc Hieu Duong vu Thai Ha le Huu Doanh Department of Stem Cell Research and Application National Hospital of Dermatology and Venereology Hanoi Vietnam Department of Healthcare Activity Direction National Hospital of Dermatology and Venereology Hanoi Vietnam Department of Dermatology Hanoi Medical University Hanoi Vietnam

Objective: Botulinum toxin type A is frequently used to treat crow’s feet lines. However, the optimal dose and injection sites are still controversial. The objective of this study was to compare the efficacy of different botulinum toxin type A injection patterns for the treatment of crow’s ***: This single-center, retrospective, clinical study was conducted at the National Hospital of Dermatology and Venereology from July 2020 to December 2020. Data on 60 patients with crow’s feet were collected and divided into 2 groups (3-or 4-point intramuscular injection) according to the intramuscular injection technique the patients received. The treatment efficacy was assessed based on the changes in the Crow’s Feet Grading Scale score at 1, 4, and 16 weeks after treatment. Repeated measures analysis of variance was used for the assessment of changes in scores over time between the two ***: After treatment, the average Crow’s Feet Grading Scale score was significantly decreased compared with the pretreatment score at all timepoints (1, 4, and 16 weeks) in both states (dynamic: For 3-point intramuscular injection technique, 1 week: 1.90 ± 0.71vs. 2.97 ± 0.56; 4 weeks: 1.87 ± 0.68vs. 2.97 ± 0.56; 16 weeks: 2.60 ± 0.67vs. 2.97 ± 0.56. For 4-point intramuscular injection technique, 1 week: 1.73 ± 0.83vs. 3.03 ± 0.49; 4 weeks: 1.73 ± 0.74vs. 3.03 ± 0.49; 16 weeks: 2.57 ± 0.68vs. 3.03 ± 0.49, allP < 0.001. and static: For 3-point intramuscular injection technique, 1 week: 1.20 ± 0.89vs. 2.20 ± 0.85; 4 weeks:1.20 ± 0.89vs. 2.20 ± 0.85; 16 weeks: 1.87 ± 0.97vs. 2.20 ± 0.85; For 4-point intramuscular injection technique, 1 week: 1.50 ± 0.86vs. 2.30 ± 0.84; 4 weeks: 1.33 ± 0.84vs. 2.30 ± 0.84; 16 weeks: 1.87 ± 0.97vs. 2.30 ± 0.84. AllP < 0.001). The average subjective patient-rated satisfaction scores after treatment were significantly higher in the 4-point injection group than in the 3-point injection group (P = 0.028). The adverse events were post-injection bruisi

关键词： botulinum toxin type A crow’s feet lines injection site dose

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