Organoid intelligence:Integration of organoid technology and artificial intelligence in the new era of in vitro models

作     者：Huaiyu Shi Andrew Kowalczewski Danny Vu Xiyuan Liu Asif Salekin Huaxiao Yang Zhen Ma 

作者机构：Department of Biomedical&Chemical EngineeringSyracuse UniversitySyracuseNYUSA BioInspired Institute for Material and Living SystemsSyracuse UniversitySyracuseNYUSA Department of Mechanical&Aerospace EngineeringSyracuse UniversitySyracuseNYUSA Department of Electrical Engineering&Computer ScienceSyracuse UniversitySyracuseNYUSA Department of Biomedical EngineeringUniversity of North TexasDentonTXUSA 

出 版 物：《Medicine in Novel Technology and Devices》 (医学中新技术与新装备（英文）)

年 卷 期：2024年第21卷第1期

页      面：39-44页

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 12[管理学] 1201[管理学-管理科学与工程(可授管理学、工学学位)] 081104[工学-模式识别与智能系统] 08[工学] 0835[工学-软件工程] 0836[工学-生物工程] 0811[工学-控制科学与工程] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

基　　金：NIH[R01HD101130,R15HD108720] NSF[CMMI-2130192,CBET-1943798] Research Seed Grants(2021 and 2023)from UNT Research and Innovation Office(H.X.Y.),Syracuse University intramural CUSE grant[II-3245-2022](Z.M.) 

主　　题：Organoids Machinelearning Deep learning Artificial intelligence Stem cells 

摘      要：Organoid Intelligence ushers in a new era by seamlessly integrating cutting-edge organoid technology with the power of artificial ***,three-dimensional miniature organ-like structures cultivated from stem cells,offer an unparalleled opportunity to simulate complex human organ systems in *** the convergence of organoid technology and AI,researchers gain the means to accelerate discoveries and insights across various *** intelligence algorithms enable the comprehensive analysis of intricate organoid behaviors,intricate cellular interactions,and dynamic responses to *** synergy empowers the development of predictive models,precise disease simulations,and personalized medicine approaches,revolutionizing our understanding of human development,disease mechanisms,and therapeutic *** Intelligence holds the promise of reshaping how we perceive in vitro modeling,propelling us toward a future where these advanced systems play a pivotal role in biomedical research and drug development.