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The mediatory role of water quality on the association between extreme precipitation events and infectious diarrhea in the Yangtze River Basin,China

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Fundamental Research 2024年第3期4卷 495-504页

作者： Junfeng Yu Liang Zhao Xin-Zhong Liang hung chak ho Masahiro Hashizume Cunrui Huang School of Public Health Sun Yat-sen UniversityGuangzhou 510080China The State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Department of Atmospheric and Oceanic Science University of MarylandCollege ParkMD 20740USA Department of Public and International Affairs City University of Hong KongHong Kong 999077China Department of Global Health Policy Graduate School of MedicineThe University of TokyoTokyo 113-0033Japan Vanke School of Public Health Tsinghua UniversityBeijing 100084China Institute of Healthy China Tsinghua UniversityBeijing 100084China

Extreme precipitation is exacerbating the burden of infectious diarrhea in the context of climate change,it is necessary to identify the critical and easy-to-intervene intermediate factors for public health *** quality may be the most important mediator,while relevant empirical evidence is *** study aimed to examine the role of water quality in the process of infectious diarrhea caused by extreme *** infectious diarrhea cases,meteorological factors and water quality data in Yangtze River Basin in China between October 29,2007 to February 19,2017 were ***-stage statistical models were used to estimate city-specific extreme precipitation,water quality and infectious diarrhea relationships that were pooled to derive regional estimates.A causal mediation analysis was used to assess the mediation effect of water *** Yangtze River Basin,extreme precipitation events had a significant impact on infectious diarrhea(Incidence Rate Ratios[IRR]:1.027,95%Confidence Interval[CI]:1.013~1.041).After extreme precipitation events,the dissolved oxygen(DO)in surface water decreased(-0.123 mg/L,95%CI:-0.159 mg/L~-0.086 mg/L),while the un-ionized ammonia(NH(3)-N)increased(0.004 mg/L,95%CI:0.001 mg/L~0.006 mg/L).The combined overall effect of DO and NH(3)-N on infectious diarrhea showed that both low and high concentrations were associated with an increased risk of infectious *** causal mediation analysis showed that the mediation proportion of the two water quality indexes(DO and NH(3)-N)is 70.54%(Phose that take into account more direct and easy-to-intervene water quality indicators should be encouraged by future policies.

关键词： Extreme precipitation Infectious diarrhea Water quality Dissolved oxygen Un-ionized ammonia Mediation analysis

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Spatiotemporal Variations and Controls on Anthropogenic Heat Fluxes in 12 Selected Cities in the Eastern China

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Chinese Geographical Science 2021年第3期31卷 444-458页

作者： CAO Zheng WEN Ya SONG Song hung chak ho SUN Hui School of Geographical Sciences Guangzhou UniversityGuangzhou 510006China Guangdong Province Engineering Technology Research Center for Geographical Conditions Monitoring and Comprehensive Analysis Guangzhou 510006China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China College of Resources and Environment South China Agricultural UniversityGuangzhou 510642China S.Department of Urban Planning and Design The University of Hong KongHong Kong 999077China

Spatiotemporal variations of anthropogenic heat flux(AHF)is reported to be associated with global ***,confined to the low spatial resolution of energy consumption statistical data,details of AHF was not well *** obtain high spatial resolution data of AHF,Defense Meteorological Satellite Program/Operational Linescan System(DMSP/OLS)nighttime light time-series product and Moderate Resolution Imaging Spectroradiometer(MODIS)satellite monthly normalized difference vegetation index(NDVI)product were applied to construct the human settlement *** on the spatial regression relationship between human settlement index and energy consumption data.A 1-km resolution dataset of AHF of 12 selected cities in the eastern China was *** least-squares(OLS)model was applied to detect the mechanism of spatial patterns of *** showed that industrial emission in selected cities of the eastern China was accountable for 63%of the total *** emission in megacities,such as Tianjin,Jinan,Qingdao,and Hangzhou,was most *** increasing speed in most areas in the chosen cities was quite *** growth or extremely high growth of AHF were located in central downtown *** Beijing,Shanghai,Guangzhou,Jinan,Hangzhou,Changzhou,Zhaoqing,and Jiangmen,a single kernel of AHF was *** influencing factors showed that precipitation,temperature,elevation,normalized different vegetation index,gross domestic product,and urbanization level were positive with ***,this investigation implied that urbanization level and economic development level might dominate the increasing of AHF and the spatial heterogeneousness of *** urbanization level or economic development level resulted in high increasing speeds of *** findings provide a novel way to reconstruct of AHF and scientific supports for energy management strategy development.

关键词： anthropogenic heat flux(AHF) Defense Meteorological Program/Operational Linescan System(DMSP/OLS)data spatiotemporal variations influencing factors eastern China

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Evaluating the short-term effect of ambient temperature on non-fatal outdoor falls and road traffic injuries among children and adolescents in China: a time-stratified case-crossover study

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Frontiers of Environmental Science & Engineering 2023年第9期17卷 105-113页

作者： Hao Zheng Jian Cheng hung chak ho Baoli Zhu Zhen Ding Wencong Du Xin Wang Yang Yu Juan Fei Zhiwei Xu Jinyi Zhou Jie Yang Department of Environmental Health Jiangsu Provincial Center for Disease Control and PreventionNanjing 210009China Department of Epidemiology and Biostatistics School of Public HealthAnhui Medical UniversityHefei 230032China Anhui Province Key Laboratory of Major Autoimmune Disease Hefei 230032China Department of Anaesthesiology School of Clinical MedicineThe University of Hong KongHong Kong 999077China Department of Noncommunicable Diseases Jiangsu Provincial Center for Disease Control and PreventionNanjing 210009China Department of Child and Adolescent Health Promotion Jiangsu Provincial Center for Disease Control and PreventionNanjing 210009China School of Public Health University of QueenslandQueensland 4006Australia

studies have suggested that non-optimal temperatures may increase the risk of injury,epidemiological studies focusing on the association between temperature and non-fatal injury among children and adolescents are ***,we investigated the short-term effect of ambient temperature on non-fatal falls and road traffic injuries(RTIs)among students across Jiangsu Province,*** data and records of non-fatal outdoor injuries due to falls and RTIs among students aged 6–17 were collected during 2018–*** performed a time-stratified case-crossover analysis with a distributed lag nonlinear model to examine the effect of ambient temperature on the risk of *** meteorological exposure was estimated based on the address of the selected *** also performed stratified analyses by sex,age,and area.A total of 57322 and 5455 cases of falls and RTIs were collected,*** observed inverted U-shaped curves for temperatureinjury associations,with maximum risk temperatures at 18℃(48th of daily mean temperature distribution)for falls and 22℃(67th of daily mean temperature distribution)for *** corresponding odds ratios(95%confidence intervals)were 2.193(2.011,2.391)and 3.038(1.988,4.644)for falls and RTIs,***,there was a significant age-dependent trend in which the temperature effect on falls was greater in older students(P-trend<0.05).This study suggests a ignificant association between ambient temperature and students’outdoor falls and *** findings may help advance tailored strategies to reduce the incidence of outdoor falls and RTIs in children and adolescents.

关键词： Ambient temperature Fall Road traffic injury Student China

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Solitary extraovarian primary peritoneal carcinoma with direct invasion into the liver,diaphragm and lung without peritoneal dissemination or distant metastasis

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 322-325页

作者： Billy ho hung Cheung Wong hoi She Siu Lun ho Albert Chi Yan Chan Chung Mau Lo Tan To Cheung Department of Surgery The University of Hong KongHong KongChina Department of Pathology The University of Hong KongHong KongChina

To the Editor:Extraovarian primary peritoneal carcinoma(EOPPC)is an uncommon malignancy with many similarities to epithelial ovarian carcinoma in histological,clinical,and etiological aspects[1].This phenomenon is explained by their common embryonal origin,in which both develop from the coelomic epithelium in the early embryological *** their similarities,the incidence of EOPPC is significantly lower than that of epithelial ovarian carcinoma(6.78 cases per million vs.120.5 cases per million)[1].

关键词： peritoneal invasion metastasis

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Machine learning based models for predicting compressive strength of geopolymer concrete

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 1028-1049页

作者： Quang-Huy LE Duy-hung NGUYEN Thanh SANG-TO Samir KHATIR hoang LE-MINH Amir H.GANDOMI Thanh CUONG-LE Center for Engineering Application and Technology Solutions Ho Chi Minh City Open UniversityHo Chi Minh 700000Vietnam Institute of Civil Engineering Ho Chi Minh City University of TransportHo Chi Minh 700000Vietnam Faculty of Engineering&Information Technology University of Technology SydneyUltimoNSW 2007Australia

Recently,great attention has been paid to geopolymer concrete due to its advantageous mechanical and environmentally friendly *** effort has been made in experimental studies to advance the understanding of geopolymer concrete,in which compressive strength is one of the most important *** facilitate engineering work on the material,an efficient predicting model is *** this study,three machine learning(ML)-based models,namely deep neural network(DNN),K-nearest neighbors(KNN),and support vector machines(SVM),are developed for forecasting the compressive strength of the geopolymer concrete.A total of 375 experimental samples are collected from the literature to build a database for the development of the predicting models.A careful procedure for data preprocessing is implemented,by which outliers are examined and removed from the database and input variables are standardized before feeding to the fitting *** standard K-fold cross-validation approach is applied for evaluating the performance of the models so that overfitting status is well managed,thus the generalizability of the models is *** effectiveness of the models is assessed via statistical metrics including root mean squared error(RMSE),mean absolute error(MAE),correlation coefficient(R),and the recently proposed performance index(PI).The basic mean square error(MSE)is used as the loss function to be minimized during the model fitting *** three ML-based models are successfully developed for estimating the compressive strength,for which good correlations between the predicted and the true values are obtained for DNN,KNN,and *** numerical results suggest that the DNN model generally outperforms the other two models.

关键词： geopolymer concrete compressive strength prediction machine-learning based model deep neural network K-nearest neighbor support vector machines

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Variability and Risk Analysis of hong Kong Air Quality Based on Monsoon and El Nino Conditions

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Advances in Atmospheric Sciences 2013年第2期30卷 280-290页

作者： Jong-Suk KIM ZhoU Wen ho Nam CHEUNG chak Hang ChoW School of Energy and Environment City University of Hong Kong Hong Kong Guy Carpenter Asia-Pacific Climate Impact Centre City University of Hong Kong Hong Kong

This study presents an exploratory analysis aimed at improving understanding of the variability of hong Kong air quality associated with different climate conditions. Significantly negative correlations were found when Nifio 3 led particulate matter 〈10 p.m PM10） and NO2 by 2 3 months over the hong Kong territory, while the other pollutants （e.g., Oa, SO2） showed modest correlations. A significant decreasing trend in visibility was observed during the autumn and winter, which has potential implications for the air-quality degradation and the endangerment of human health in hong Kong. In an E1 Nifio summer, the visibility was relatively better, while visibility in other seasons was diminished. On the other hand, in La Nifia events, significant changes occurred in visibility in winter and autumn. Air pollution indices were less sensitive to the South China Summer Monsoon （SCSM）, but a relatively high correlation existed between the East Asian Winter Monsoon （EAWM） and air pollutants. Rainfall was lower during most of the strong EAWM years compared to the weak years. This result suggests that the pollutants that accumulate in hong Kong are not easy to wash out, so concentrations remain at a higher level. Finally, based on the conditional Air Pollution Index （API） risk assessment, site-specific vulnerabilities were analyzed to facilitate the development of the air-quality warning systems in hong Kong.

关键词： air quality E1 Nifio/La Nifia Monsoon API risk hong Kong

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Epidemiology and Clonal Spread Evidence of Carbapenem-Resistant Organisms in the Center of Care and Protection of Orphaned Children, Vietnam

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Open Journal of Medical Microbiology 2024年第3期14卷 165-189页

作者： Van Kim Nguyen Pirom Noisumdaeng Pol. Maj. Katiya Ivanovitch Stephen Baker Eugene Athan Stephanie Jones Le Thi Lan Larry Croft Yin Peng Lee Tara Cassidy Van hung Tran Thi Hang Phan Huu Tinh ho Faculty of Public Health Thammasat University Bangkok Thailand Department of Prevention and Infection Control Hung Vuong Hospital HCM City Vietnam Microbiology of Faculty of Public Health Thammasat University Bangkok Thailand Thammasat University Research Unit in Modern Microbiology and Public Health Genomics Thammasat University Bangkok Thailand National Heart & Lung Institute (NHLI) University of Cambridge Cambridge UK Barwon South West Public Health Unit Geelong Australia Center for Innovation in Infectious Disease and Immunology Research (CIIDIR) Geelong Australia School of Medicine Deakin University Burwood Australia Monash Health Berwick Australia Center of Care and Protection of Orphaned Children HCM City Vietnam Charles River Laboratories Microbial Solutions Melbourne Australia Personnel Department of Nhan Dan Gia Dinh hospital HCM City Vietnam hung Vuong hospital HCM City Vietnam Department of Epidemiology Institute of Public Health HCM City Vietnam

Objective: To determine the prevalence of colonization and transmission of carbapenem-resistant Gram-negative organisms in order to develop of an effective infection prevention program. Design: Cross-sectional study with carbapenem-resistant organisms (CRO) colonization detection from the fecal specimens of 20 Health Care Workers (HCWs) and 67 residents and 175 random environment specimens from September 2022 to September 2023. Setting: A Care and Protection Centre of Orphaned Children in South of HCM City. Participants: It included 20 HCWs, 67 residents, and 175 randomly collected environmental specimens. Method: Rectal and environmental swabs were collected from 20 HCWs, 67 residents (most of them were children), and 175 environmental specimens. MELAB Chromogenic CARBA agar plates, Card NID, and NMIC-500 CPO of the BD Phoenix TM Automated Microbiology System and whole genome sequencing (WGS) were the tests to screen, confirm CROs, respectively and determine CRO colonization and transmission between HCWs, residents, and the environment. Result: We detected 36 CRO isolates, including 6, 11 and 19 CROs found in 6 HCWs, 10 residents and 19 environments. The prevalence of detectable CRO was 30% (6/20) in HCWs, 14.92% (10/67) in residents, and 10.86% (19/175) in environmental swabs in our study. WGS demonstrated CRO colonization and transmission with the clonal spread of E. coli and A. nosocomialis, among HCWs and residents (children). Conclusion: Significant CRO colonization and transmission was evident in HCWs, residents, and the center environment. Cleaning and disinfection of the environment and performing regular hand hygiene are priorities to reduce the risk of CRO colonization and transmission.

关键词： Carbapenem-Resistant Organisms Contamination Hand Hygiene Whole Genome Sequencing Infection Prevention

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Prevalence and outcomes of neonates with severe COVID-19:An observational study at Children’s hospital 1 in ho Chi Minh City,Vietnam

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Asian Pacific Journal of Tropical Medicine 2024年第9期17卷 392-399,I0001页

作者： Phung Nguyen The Nguyen Tran Thanh Thuc Nguyen Thanh hung Ngo Ngoc Quang Minh Dang Quoc Duy Tran Minh Nhut Nguyen hoang Dung Tran Nguyen Ai Nuong Dinh Nguyen Cam Tu Department of Pediatrics University of Medicine and Pharmacy at Ho Chi Minh cityHo Chi Minh CityVietnam Children’s hospital 1 Ho Chi Minh CityVietnam Pediatric Department School of MedicineVietnam National University Ho Chi Minh CityVietnam

Objective:To evaluate the impact of the severe COVID-19 pandemic on neonates and develop strategies to improve their ***:We conducted an observational cross-sectional study at Children's hospital 1(CH1)from July 25,2021,to May 31,*** neonates who had fever or respiratory symptoms or were born from mothers with COVID-19 and had a positive RT-PCR SARS-CoV-2 result would be *** classified neonates with COVID-19 into 2 groups:mild/moderate and severe for *** between groups were analyzed using Fisher's exact test/Chi-square test for categorical variables and Student's t-test/Wilcoxon Rank Sum test for continuous ***:This study included 88 newborns who had positive RT-PCR SARS-CoV-2 *** severity COVID-19 rate among neonatal cases was found to be 13.6%(12/88),with a corresponding mortality rate of 1.1%(1/88).All severe cases showed lung abnormalities as evident on chest X-ray *** addition to respiratory symptoms,a higher incidence of gastrointestinal manifestations,such as vomiting and diarrhea,was observed in the severe group,indicating a compelling *** administration of anticoagulant and anti-inflammatory drugs in the study group resulted in a satisfactory outcome with no significant ***:The COVID-19 pandemic has had a substantial impact on the well-being of *** management of COVID-19 in this population presents significant challenges.

关键词： COVID-19 Neonate Anti-inflammatory Anticoagulant

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Neighboring effect in single-atom catalysts for the electrochemical carbon dioxide reduction reaction

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eScience 2024年第1期4卷 1-16页

作者： hon ho Wong Mingzi Sun Tong Wu Cheuk Hei Chan Lu Lu Qiuyang Lu Baian Chen Bolong Huang Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARChina Research Centre for Carbon-Strategic Catalysis The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARChina

Although single-atom catalysts(SACs)have attracted enormous attention for their applications in the electrochemical reduction of CO_(2)(CO_(2)RR)due to their extraordinary catalytic activity and well-defined active centers,neighboring effects and their influence on the electrochemical performance of SACs have not been well *** this review,we present a summary of the neighboring effects on SACs for the CO_(2)RR process,where the surrounding atoms not only induce electronic modulation of the metal atom but also participate in the CO_(2)*** theoretical and experimental studies have pointed out that the neighboring sites of the anchored metal center can provide second active/adsorption locations during the catalytic process,enhancing CO_(2)RR performance *** review supplies advanced insights into the significant roles and impacts of neighboring effects on the catalytic process,which also benefit the development of advanced SACs to achieve efficient electrocatalysis.

关键词： Carbon dioxide reduction Neighboring effect Atomic catalysts Electronic modulations Active sites

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The half-degree matters for heat-related health impacts under the 1.5℃ and 2℃ warming scenarios: Evidence from ambulance data in Shenzhen, China

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Advances in Climate Change Research 2021年第5期12卷 628-637页

作者： HE Yi-Ling DENG Shi-Zhou ho hung chak WANG Hui-Bin CHEN Yang Shakoor HAJAT REN Chao ZhoU Bai-Quan CHENG Jian Wenbiao HU MA Wen-Jun HUANG Cun-Rui School of Public Health Sun Yat-sen UniversityGuangzhou51000China Shanghai Typhoon Institute China Meteorological AdministrationShanghai200030China Department of Urban Planning and Design University of Hong KongHong KongChina State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing100081China Department of Public Health Environments and SocietyLondon School of Hygiene&Tropical MedicineLondonWC1H 9SHUnited Kingdom Faculty of Architecture University of Hong KongHong KongChina Department of Epidemiology and Biostatistics School of Public HealthAnhui Medical UniversityHefei230032China School of Public Health and Social Work Queensland University of TechnologyBrisbane4059Australia Guangdong Provincial Institute of Public Health Guangdong Provincial Center for Disease Control and PreventionGuangzhou510399China School of Public Health Zhengzhou UniversityZhengzhou450001China Shanghai Key Laboratory of Meteorology and Health Shanghai Meteorological ServiceShanghai200030China Vanke School of Public Health Tsinghua UniversityBeijing100084China

The Paris Agreement has prompted much interest in the societal and health impacts of limiting global warming to 1.5 ℃ and 2 ℃. Previous assessments of differential impacts of two targets indicate that 1.5 ℃ warming target would substantially reduce the impact on human health compared to 2 ℃, but they mainly focused on the magnitude of temperature changes under future climate change scenarios without any consideration of greater frequency of cumulative heat exposures within a day. Here we quantified the health risks of compound daytime and nighttime hot extremes using morbidity data in a megacity of China, and also identified the time-period of heat exposure with higher risks. Then we projected future morbidity burden attributable to compound hot extremes due to the half-degree warming. We estimated that the 2 ℃ warming scenario by 2100 as opposed to 1.5 ℃ would increase annual heat-related ambulance dispatches by 31% in Shenzhen city. Substantial additional impacts were associated with occurrence of consecutive hot days and nights, with ambulance dispatches increased by 82%. Our results suggested that compound hot extremes should be considered in assessment of heat-related health impacts, particularly in the context of climate change. Minimizing the warming of climate in a more ambitious target can significantly reduce the health damage.

关键词： Climate change Compound hot extreme Paris agreement Human health Morbidity effect

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