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A Ku-band image-rejection filtering LNA MMIC in 150-nm GaN-on-SiC technology

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Science China(Information Sciences) 2024年第1期67卷 318-319页

作者： huiyang li Jinxu XU Xiuyin ZHANG School of Electronic and Information Engineering South China University of Technology School of Microelectronics South China University of Technology

The low noise amplifier (LNA) is one of the most important circuits in the transceiver. Many high-performance LNAs have been demonstrated based on Ga N processes. For instance, by using a hybrid-matching topology with...

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Layered Ag-graphene films synthesized by Gamma ray irradiation for stable lithium metal ano des in carb on ate-based electrolytes

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Journal of Energy Chemistry 2022年第1期31卷 354-363,I0010页

作者： Jiaxiang liu Haoshen Ma Zhipeng Wen huiyang li Jin Yang Nanbiao Pei Peng Zhang Jinbao Zhao College of Energy Xiamen UniversityXiamen 361102FujianChina State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy MaterialsEngineering Research Center of Electrochemical TechnologyMinistry of EducationState-Province Joint Engineering Laboratory of Power SourceTechnology for New Energy VehicleCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005FujianChina

lithium metal batteries are considered as high energy density battery systems with very promising prospects and have bee n widely ***,The uncon trollable plating/strippi ng behavior,infinite volume change and den drites formation of lithium metal anode restrict the applicati *** unc on trolled n ucleati on of lithium caused by the non uniform multi-physical field distributions,can lead to the undesirable lithium ***,a graphene composite uniformly loaded with Ag nano-particles(Ag NPs)is prepared through a facile Gamma ray irradiation method and assembled into self-supported film with layered structure(Ag-rGO film).Whe n such film is used as a lithium metal an ode host,the uncontrolled deposition is converted into a highly nucleation-induced *** one hand,the Ag NPs distributed between the in terlayers of graphe ne can preferentially induce lithium nu cleati on and en able uniform deposition morphology of lithium between *** the other hand,the stable layered graphene structure can accommodate volume change,stabilize the interface between anode and electrolyte and inhibit dendrites ***,the layered Ag-rGO film as anode host can reach a high Coulombic efficiency over 93.3% for 200 cycle(786 h)at a current density of 1 mA cm^(-2) for 2 mAh cm^(-2) in carbonate-based *** work proposes a facile Gamma ray irradiation method to prepare metal/3D-skeleton structure as lithium anode host and demonstrates the potential to regulate the lithium metal deposition behaviors via manipulating the distribution of lithiophilic metal(***)in 3D *** may offer a practicable thinking for the subsequent design of the lithium metal anode.

关键词： lithium metal anode Gamma Ray irradiation Ag nano-particles Inductive effect Layered structure Uniform lithium deposition

Immunorecognition of estrogen and androgen receptors in the brain and thoracic ganglion mass of mud crab,Scylla paramamosain

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Progress in Natural Science:Materials International 2008年第6期18卷 691-695页

作者： Haihui Ye*,huiyang Huang,Shaojing li,Guizhong Wang Department of Oceanography,Xiamen University,Xiamen 361005,China Department of Oceanography Xiamen University Xiamen 361005 China

The brain and the thoracic ganglion of a crustacean can synthesize and secrete gonad-stimulating hormone(GSH)which stimulates the maturation of *** the previous experiments,sex steroid hormones(estradiol,testosterone,progesterone,etc.)have been detected from the ***,the feedback regulation of sex steroid hormones on the brain and the thoracic ganglion of the crustacean has not been reported so *** the present experiment,monoclonal antibodies were applied to investigate the immuno-recognition of estrogen receptor(ER)and androgen receptor(AR)in the brain and the thoracic ganglion mass of Scylla *** results showed that the distribution of the immunopositive substances of ER and AR was extremely *** distributed in the protocerebrum,deutocerebrum and tritocerebrum of the brain,and mainly in *** the thoracic ganglion mass,immuno-positive substances distributed in the subesophageal ganglion,thoracic ganglion and abdominal ganglion,and mostly in subesophageal *** substances of ER and AR mostly existed in the cytoplasm of *** present study will provide mor-phological evidence for the origin and the evolution of ER and *** addition,the immunoreactivities of ER and AR suggested that the estrogen and androgen may be involved in the feedback regulation of crustacean neuroendocrine.

关键词： Scylla paramamosain Estrogen receptor Androgen receptor Brain Thoracic ganglion mass Immunocytochemistry

Cu(II)-baicalein enhance paracrine effect and regenerative function of stem cells in patients with diabetes

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Bioactive Materials 2024年第6期36卷 455-473页

作者： Kaijing liu Ruihao li Shusen Wang Xue Fu Ni Zhu Xiaoyu liang huiyang li Xiaoli Wang Le Wang Yongjun li Jianwu Dai Jing Yang Key Laboratory of Advanced Medical Materials and Devices Institute of Biomedical EngineeringTianjin Institutes of Health ScienceChinese Academy of Medical Science&Peking Union Medical CollegeTianjin300192China Tianjin Medical Health Research Institute Tianjin300192China Organ Transplant Center Tianjin First Central HospitalNankai UniversityTianjinChina Tianjin Clinical Research Center for Organ Transplantation TianjinChina Department of Vascular Surgery Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical Science&Peking Union Medical CollegeBeijing100730China Graduate School of Peking Union Medical College Beijing100730China

The development of engineered or modified autologous stem cells is an effective strategy to improve the efficacy of stem cell *** this study,the stemness and functionality of adipose stem cells derived from type 1 diabetic donors(T1DM-ASC)were enhanced by treatment with Cu(II)-baicalein microflowers(Cu-MON).After treatment with Cu-MON,T1DM-ASC showed enhanced expression of the genes involved in the cytokine-cytokine receptor interaction pathway and increased cytokine *** the top 13 differentially expressed genes between T1DM-ASC and Cu-MON-treated T1DM-ASC(CMTA),some genes were also expressed in HUVEC,Myoblast,Myofibroblast,and Vascular Smooth Muscle cells,inferring the common role of these cell *** vivo experiments showed that CMTA had the same therapeutic effect as adipose-derived stem cells from non-diabetic donors(ND-ASC)at a 15%cell dose,greatly reducing the treatment *** together,these findings suggest that Cu-MON promoted angiogenesis by promoting the stemness and functionality of T1DM-ASC and influencing multiple overall repair processes,including paracrine effects.

关键词： Angiogenesis Adipose stem cells Type 1 diabetes mellitus Paracrine effect Regenerative function

Highly sensitive H_(2)O_(2)-scavenging nano-bionic system for precise treatment of atherosclerosis

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Acta Pharmaceutica Sinica B 2023年第1期13卷 372-389页

作者： Xiaoyu liang huiyang li Xuanling li Xinxin Tian Aiai Zhang Qingzhi Luo Jianwei Duan Youlu Chen liyun Pang Chen li Xing-Jie liang Yong Zeng Jing Yang Tianjin Key Laboratory of Biomaterial Research Institute of Biomedical EngineeringChinese Academy of Medical Science and Peking Union Medical CollegeTianjin 300192China Beijing Anzhen Hospital of Capital Medical University Beijing 100029China Medical College of Qinghai University Xining 810016China CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology of ChinaBejing 100190China The First Affiliated Hospital of Hebei North University Zhangjiakou 075061China First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin 300381China

In atherosclerosis,chronic inflammatory processes in local diseased areas may lead to the accumulation of reactive oxygen species(ROS).In this study,we devised a highly sensitive H_(2)O_(2)-scavenging nanobionic system loaded with probucol(RPP-PU),to treat atherosclerosis more *** RPP material had high sensitivity to H_(2)O_(2),and the response sensitivity could be reduced from 40 to 10μmol/L which was close to the lowest concentration of H_(2)O_(2)levels of the pathological ***-PU delayed the release and prolonged the duration of PU in *** Apolipoprotein E deficient(ApoE-/-)mice,RPP-PU effectively eliminated pathological ROS,reduced the level of lipids and related metabolic enzymes,and significantly decreased the area of vascular plaques and *** study demonstrated that the H_(2)O_(2)-scavenging nanobionic system could scavenge the abundant ROS in the atherosclerosis lesion,thereby reducing the oxidative stress for treating atherosclerosis and thus achieve the therapeutic goals with atherosclerosis more desirably.

关键词： Highly sensitive H_(2)O_(2)-scavenging Nano-bionic system Atherosclerosis Oxidative stress Precise Target Pathological environment

Significant difference between sirolimus and paclitaxel nanoparticles in antiproliferation effect in normoxia and hypoxia: The basis of better selection of atherosclerosis treatment

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Bioactive Materials 2021年第3期6卷 880-889页

作者： Youlu Chen Yong Zeng Xiaowei Zhu lifu Miao Xiaoyu liang Jianwei Duan huiyang li Xinxin Tian liyun Pang Yongxiang Wei Jing Yang Tianjin Key Laboratory of Biomaterial Research Institute of Biomedical EngineeringChinese Academy of Medical Science and Peking Union Medical CollegeTianjin300192PR China Beijing Institute of Heart Lung and Blood Vessel Disease Beijing Anzhen HospitalCapital Medical UniversityBeijing100029PR China Henan Center for Patent Examination and Cooperation of the Patent Office of the State Intellectual Property Office Henan450002PR China Heart Center The First Hospital of Tsinghua UniversityBeijing100016PR China Biomedical Barriers Research Center Institute of Biomedical EngineeringChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin300192PR China

Compared with paclitaxel,sirolimus has been more used in the treatment of vascular restenosis gradually as an anti-proliferative drug,but few basic studies have elucidated its *** anti-proliferative effects of sirolimus or paclitaxel have been demonstrated by numerous studies under normoxia,but few studies have been achieved focusing *** this study,porcine carotid artery injury model and classical cobalt chloride hypoxia cell model were *** nanoparticles(SRM-NPs),paclitaxel nanoparticles(PTX-NPs)and blank nanoparticles(Blank-NPs)were prepared *** effect of RPM-NPs on the degree of stenosis,proliferative index and the expression of PCNA after 28 days of porcine carotid artery injury model was *** with saline group and SRM groups,SRM-NPs group suppressed vascular stenosis,proliferative index and the expression of PCNA(Plial cell(EC)and smooth muscle cell(SMC)were pre-treated with cobaltous chloride,followed by SRM-NPs,PTX-NPs,Blank-NPs or PBS control treating,the effects on cell proliferation,HIF-1 expression and glycolysis were ***-NPs could inhibit EC and SMC proliferation under hypoxia,while PTX-NPs couldn't(Plimus and paclitaxel NPs in anti-proliferation effect under normoxia and hypoxia may due to the different inhibitory effects on HIF-1αexpression and *** conclusion,these results suggest that sirolimus can inhibit the proliferation of hypoxic cells more effectively than *** observations may provide a basis for understanding clinical vascular stenosis therapeutic differences between rapamycin and paclitaxel.

关键词： Atherosclerosis Sirolimus Paclitaxel Hypoxia HIF-1α Glycolysis

ROS-responsive capsules engineered from EGCG-Zinc networks improve therapeutic angiogenesis in mouse limb ischemia

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Bioactive Materials 2021年第1期6卷 1-11页

作者： Zuoguan Chen Jianwei Duan Yongpeng Diao Youlu Chen Xiaoyu liang huiyang li Yuqing Miao Qing Gao liang Gui Xiaoli Wang Jing Yang Yongjun li Department of Vascular Surgery Beijing HospitalNational Center of GerontologyInstitute of Geriatric Medicine.Chinese Academy of Medical Sciences and Peking Union Medical College.Graduate School of Peking Union Medical CollegeBeijing100730PR China Tianjin Key Laboratory of Biomaterial Research Institute of Biomedical EngineeringChinese Academy of Medical Sciences and Peking Union Medical CollegeTianjin300192PR China

The successful treatment of limb ischemia requires that promote angiogenesis along with microenvironment *** ions have been reported to stimulate angiogenesis,but application was limited to the toxicity *** hypothesized that zinc based metal-EGCG capsule(EGCG/Zn Ps)can achieve sustained release Zn2+resulting in reduced toxicity and improve angiogenesis as well as the improvement of microenvironment by ROS scavenging of *** surface morphology,zeta potential,infrared absorbance peaks and zinc ion release profile of the EGCG/Zn Ps were *** vitro,EGCG/Zn showed significantly antioxidant,antiinflammatory and induced cell migration *** addition,EGCG/Zn Ps enabled the sustained release of zinc ions,which reduced cytotoxicity and enhanced the secretion of vascular endothelial growth factor(VEGF)in vitro and in *** mouse models of limb ischemia,EGCG/Zn Ps promoted angiogenesis and cell proliferation in ischemic ***,EGCG/Zn Ps group exhibited the most significant recovery of limb ischemic score,limb temperature and blood flow than other *** conclusion,EGCG/Zn Ps is a safe and promising approach to combine the merit of Zn2+and EGCG,thus enabling the direct application to limb ischemia.

关键词： Polyphenol metal networks Green tea polyphenol Zinc Angiogenesis limb ischemia disease

Effect of electron-withdrawing groups in conjugated bridges： molecular engineering of organic sensitizers for dyesensitized solar cells

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Frontiers of Optoelectronics 2016年第1期9卷 60-70页

作者： Jie SHI Zhaofei CHAI Runli TANG huiyang li Hongwei HAN Tianyou PENG Qianqian li Zhen li Department of Chemistry Hubei Key Lab on Organic and Polymeric Opto-Electronic Materials Wuhan University Wuhan 430072 China Hubei Key Laboratory of Oilcrops lipid Chemistry and Nutrition Oil Crops Research Institute Chinese Academy of Agricultural Sciences Wuhan 430062 China Michael Gratzel Center for Mesoscopic Solar Cells Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074 China

Four organic sensitizers containing quinoxaline or benzoxadiazole as an auxiliary electron acceptor in conjugated bridge were synthesized and utilized for dyesensitized solar cells （DSSCs）. It was found that the incorporation of different electron-withdrawing moieties can affect the absorption spectra, electronic properties, the interfacial interactions and then the overall conversion efficiencies significantly. Therefore, the appropriate selection of the auxiliary acceptor was important to optimize the photovoltaic performance of solar cells. Among these sensitizers, li-44 based solar cell showed the best photovoltaic performance： a shortcircuit photocurrent density （Jsc） of 13.90 mA/cm2, an open-circuit photovoltage （Voc） of 0.66 V, and a fill factor （FF） of 0.66, corresponding to an overall conversion efficiency of 6.10% under standard global AM 1.5 solar light conditions.

关键词： dye-sensitized solar cells (DSSCs) auxiliary electron acceptor quinoxaline benzoxadiazole

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混凝沉淀法去除饮用水中痕量磷的试验

沈阳建筑大学学报（自然科学版） 2012年第1期28卷 140-144页

作者：李亚峰李辉洋刘莎沈阳建筑大学市政与环境工程学院辽宁沈阳110168

目的去除饮用水中的痕量磷,优选饮用水除磷混凝剂,并对混凝除磷的影响因素进行研究.方法应用六联搅拌机对比研究三氯化铁、聚合硫酸铁、聚合氯化铝、聚合氯化铝铁以及硫酸亚铁对饮用水中痕量磷的去除效果,并分析pH值、水温、水中共存离... 详细信息

目的去除饮用水中的痕量磷,优选饮用水除磷混凝剂,并对混凝除磷的影响因素进行研究.方法应用六联搅拌机对比研究三氯化铁、聚合硫酸铁、聚合氯化铝、聚合氯化铝铁以及硫酸亚铁对饮用水中痕量磷的去除效果,并分析pH值、水温、水中共存离子对最佳混凝剂除磷效果的影响.结果 FeCl3和PFS对饮用水中痕量磷的去除效果最好,在混凝剂投入量为15 mg/L,pH值为6～7,温度在5～25℃时,饮用水中的磷能够从80μg/L降到3μg/L以下;温度在35℃时除磷难以达到饮用水生物稳定的限制范围,通过提高混凝剂的投加量能够保证除磷效果满足要求;SO42-、Cl-对除磷影响小,CO32-对除磷效果有一定干扰,通过调节原水pH值可以降低其干扰.结论 FeCl3和PFS对饮用水中痕量磷具有理想的去除效果,处理后的水满足饮用水生物稳定的限制范围.

关键词：饮用水混凝沉淀痕量磷影响因素