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Moxibustion of Zusanli(ST36)and Shenshu(BL23)alleviates the inflammation of rheumatoid arthritis in rats through regulating macrophage migration inhibitory factor/glucocorticoids signaling

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Journal of Traditional Chinese Medicine 2024年第2期44卷 353-361页

作者： ZHANG Linlin ZHONG Yumei LU Wenting SHANG Yanan GUO Yanding LUO Xiaochao CHEN yang LUO Kun HU Danhui YU huiling ZHOU Haiyan Acupuncture and Moxibustion College Chengdu University of Traditional Chinese MedicineChengdu 610075China Department of Painology First People's Hospital of ChengduChengdu 610095China Chinese Evidence-Based Medicine Centre West China HospitalSichuan UniversityChengdu 610044China Traditional Chinese Medicine College Chongqing Medical UniversityChongqing 400016China External treatment center First People's Hospital of ChengduChengdu 610095China

OBJECTIVE:To test the hypothesis that moxibustion may inhibit rheumatoid arthritis(RA)synovial inflammation by regulating the expression of macrophage migration inhibitory factor(MIF)/glucocorticoids(GCs).METHODS:Fifty male Sprague-Dawley rats were randomly divided into five groups(n=10 each):blank Control(CON)group,RA Model(RA)group,Moxibustion(MOX)group,MIF inhibitor(S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester(ISO-1)group,and Moxibustion+MIF inhibitor ISO-1(MOX+ISO-1)*** in the ISO-1 group and ISO-1+MOX group were intraperitoneally injected with the inhibitor *** rats in the RA group,ISO-1 group,MOX group,and ISO-1+MOX group were injected with Freund's complete adjuvant(FCA)in the right hind footpad to establish an experimental RA rat *** the MOX group and MOX+ISO-1 group,rats were treated with *** thickness of the footpads of the rats in each group was measured at three-time points before,after modeling and after moxibustion *** contents of serum MIF,corticosterone(CORT),tumor necrosis factor-α(TNF-α)and interleukin-1β(IL-1β)were detected by enzyme-linked immunosorbent assay;and the contents of synovial MIF were detected by Western ***-eosin(HE)staining method was used to observe the pathological changes of synovial tissue under a section light microscope,and pathological scoring was performed according to the grading standard of the degree of synovial tissue ***:Moxibustion was found to reduce the level of MIF and alleviate inflammation in RA rats in this *** addition,after inhibiting the expression of MIF,the level of CORT increased,and the level of TNF-α *** RA rats with inhibited MIF by moxibustion,the level of CORT was almost unchanged,but the level of TNF-α further *** correlation analysis data suggested that MIF was positively related to the expression of TNF-α and negatively correlated with the expression of ***:Reducing MIF to

关键词： rheumatoid arthritis macrophage migration inhibitory factor moxibustion corticosterone glucocorticoids

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明清浙江家族祭会演剧考论

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戏剧艺术 2015年第1期 92-99,107页

作者：杨惠玲厦门大学人文学院

家族祭会是专门从事祭祀的组织。明清两代,浙江绍兴和宁波等地由家族祭会主持的演剧活动相当活跃,不仅促进了家族的文化建设,同时也有助于昆曲艺术的繁荣。从这一点来看,家族文化和昆曲艺术形成了互相影响、促进的关系。

关键词：家族祭祀祭会演剧

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Investigating spatio-temporal characteristics and influencing factors for green energy consumption in China

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Geoscience Frontiers 2024年第3期15卷 221-236页

作者： Xiaowei Ma Shimei Weng Jun Zhao huiling Liu Hongyun Huang School of Finance Anhui University of Finance and EconomicsBengbu 233030PR China Hefei Advanced Research Institute Anhui University of Finance and EconomicsHefei 230041PR China School of Mathematics and Statistics Fujian Normal UniversityFuzhou 350117PR China School of Economics and Management Beijing University of Chemical TechnologyBeijing 100029PR China School of Economics Hefei University of TechnologyHefei 230601PR China Qingdao Institute of Humanities and Social Sciences Shandong UniversityQingdao 266237PR China Center for Yellow River Ecosystem Products Shandong UniversityQingdao 266237PR China

The green transformation of energy consumption is beneficial for promoting green development in *** study constructed a green energy consumption evaluation index system and measured the green energy consumption levels in 30 provinces of China from 2000 to 2019 using the fuzzy comprehensive evaluation *** study further employed the spatial Durbin model to examine influencing factors and spillover effects of green energy *** results showed that,temporally,China’s green energy consumption levels had a fluctuating upward ***,spatially,the overall levels of green energy consumption in China showed apparent characteristics of“high in the west and low in the east”.In terms of influencing factors,environmental regulations played an important role in promoting green energy consumption in the region,while economic development,opening up,and industrial structure had considerably inhibiting ***,economic development,opening up,and industrial structure of neighboring regions showed marked positive spillover effects,while urbanization level and technological innovation showed substantial negative spillover *** regional heterogeneity test results showed that environmental regulation and industrial structure rationalization were the important factors for promoting green energy consumption in the eastern region,environmental regulation played an important driving role in the central region,and opening to the outside world and technological innovation helped improve the level of green energy consumption in the western region.

关键词： Energy green consumption Spatial and temporal characteristics Influencing factors Spatial Durbin model Regional heterogeneity

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Food nutrition and toxicology targeting on specific organs in the era of single-cell sequencing

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Food Science and Human Wellness 2024年第1期13卷 75-89页

作者： Xiaofei Wang Xiaowen Cheng huiling Liu Xiaohuan Mu Hao Zheng National Engineering Technology Research Center for Fruit and Vegetable Processing Key Open Laboratory of Fruit and Vegetable ProcessingMinistry of Agriculture and Rural AffairsBeijing Key Laboratory of Food Non-Thermal ProcessingCollege of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100083China

Due to the complex natures of dietary food components,it is difficult to elucidate how the compounds affect host *** food often selectively presents its mechanism of action on different cell types,and participates in the modulation of targeted cells and their microenvironments within ***,the limitations of traditional in vitro assays or in vivo animal experiments cannot comprehensively examine cellular heterogeneity and the tissue-biased ***-cell RNA sequencing(sc RNA-seq)has emerged as an indispensable methodology to decompose tissues into different cell types for the demonstration of transcriptional profiles of individual *** RNA-seq applications has been summarized on three typical organs(brain,liver,kidney),and two representative immune-and tumor related health *** everincreasing role of sc RNA-seq in dietary food research with further improvement can provide sub-cellular information and the coupling between other cellular *** this review,we propose utilizing sc RNAseq to more effectively capture the subtle and complex effects of food chemicals,and how they may lead to health problems at single-cell *** novel technique will be valuable to elucidate the underlying mechanism of both the health benefits of food nutrients and the detrimental consequences food toxicants at the cellular level.

关键词： Dietary food Cellular heterogeneity Single-cell RNA sequencing Food nutrients Food toxicants

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从明清家班的历史经验看当下昆曲的保护和发展

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戏剧（中央戏剧学院学报） 2005年第1期 36-44页

作者：杨惠玲厦门大学中文系

明清两代 ,家班主要从事昆曲演出 ,取得了很高的成就 ,不仅推动了昆曲发展 ,而且完善了我国传统戏曲的舞台艺术。明清家班的成功经验主要有三点 :(一 )集中了当时文艺领域的优秀人才 ,主人多才多艺 ,教习身怀绝技 ,家伶素质良好。这些... 详细信息

明清两代 ,家班主要从事昆曲演出 ,取得了很高的成就 ,不仅推动了昆曲发展 ,而且完善了我国传统戏曲的舞台艺术。明清家班的成功经验主要有三点 :(一 )集中了当时文艺领域的优秀人才 ,主人多才多艺 ,教习身怀绝技 ,家伶素质良好。这些来自不同阶层的艺术人才组成了一个职责清楚、目标一致的艺术团体 ;(二 )主人将戏曲当作乐生而不是谋生的手段 ,为家班提供了良好的创作环境 ;(三 )坚持不懈地追求艺术上的至高境界。这些经验对当前昆曲保护工作的借鉴意义是 :(一 )建设高素质、高效率的专业队伍 ;(二 )强化以艺术为上的观念 ;(三 )

关键词：明清家班昆曲

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从明清江南望族看昆曲的文化生态——兼谈昆曲衰落的原因

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戏剧艺术 2017年第3期 49-57页

作者：杨惠玲厦门大学人文学院

任何一种文艺样式,其存在的空间、方式、审美形态和文化品格,以及盛衰的转折等,主要取决于两个因素:一是特定的文化土壤,二是围绕这一文艺样式开展的创作、观演、批评和理论等活动。昆曲的文化土壤有很大一部分是江南望族提供的,相关活... 详细信息

任何一种文艺样式,其存在的空间、方式、审美形态和文化品格,以及盛衰的转折等,主要取决于两个因素:一是特定的文化土壤,二是围绕这一文艺样式开展的创作、观演、批评和理论等活动。昆曲的文化土壤有很大一部分是江南望族提供的,相关活动也有很大一部分是江南望族组织并主持的。从这两点来看,江南望族在很大程度上决定了昆曲的生态。文化生态具有不可再生性,望族及其文化的衰落无法逆转,昆曲的兴盛也将一去不返。倘若不切实际地倡导振兴,并以创演新戏为主要的振兴之途,结果往往事与愿违。

关键词：望族昆曲文化生态

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Theoretical and experimental investigation of the resonance responses and chaotic dynamics of a bistable laminated composite shell in the dynamic snap-through mode

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 581-602页

作者： Meiqi WU Pengyu LV Hongyuan LI Jiale YAN huiling DUAN Wei ZHANG State Key Laboratory for Turbulence and Complex Systems Department of Mechanics and Engineering ScienceBIC-ESATCollege of EngineeringPeking UniversityBeijing 100871China Nanchang Innovation Institute of Peking University Nanchang 330096China Department of Mechanics Guangxi UniversityNanning 530004China

The dynamic model of a bistable laminated composite shell simply supported by four corners is further developed to investigate the resonance responses and chaotic *** existence of the 1:1 resonance relationship between two order vibration modes of the system is *** resonance response of this class of bistable structures in the dynamic snap-through mode is investigated,and the four-dimensional(4D)nonlinear modulation equations are derived based on the 1:1 internal resonance relationship by means of the multiple scales *** Hopf bifurcation and instability interval of the amplitude frequency and force amplitude curves are *** discussion focuses on investigating the effects of key parameters,e.g.,excitation amplitude,damping coefficient,and detuning parameters,on the resonance *** numerical simulations show that the foundation excitation and the degree of coupling between the vibration modes exert a substantial effect on the chaotic dynamics of the ***,the significant motions under particular excitation conditions are visualized by bifurcation diagrams,time histories,phase portraits,three-dimensional(3D)phase portraits,and Poincare ***,the vibration experiment is carried out to study the amplitude frequency responses and bifurcation characteristics for the bistable laminated composite shell,yielding results that are qualitatively consistent with the theoretical results.

关键词： bistable laminated composite shell dynamic snap-through mode Hopf bifurcation chaotic dynamics vibration experiment

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梵蒂冈图书馆藏明清中西文化交流史重要文献——对梵蒂冈图书馆藏稿抄本***.503的初步研究

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史学史研究 2016年第2期 93-98页

作者：杨慧玲北京外国语大学国际中国文化研究院北京100089

梵蒂冈图书馆作为世界上最大的天主教文献收藏地,收藏了一批珍贵的中国天主教文献。本文仅对该馆所收藏的重要中西文化交流史文献稿抄本***.503,即多明我会士黎玉范所撰述的中西文文献作出研究:介绍了黎玉范其人其事,黎玉范对中国祭祖... 详细信息

梵蒂冈图书馆作为世界上最大的天主教文献收藏地,收藏了一批珍贵的中国天主教文献。本文仅对该馆所收藏的重要中西文化交流史文献稿抄本***.503,即多明我会士黎玉范所撰述的中西文文献作出研究:介绍了黎玉范其人其事,黎玉范对中国祭祖、祭孔礼仪问题研究著作《圣教孝亲解》及原文转写,汉语-西班牙语双语词典和学习汉语会话的《拜客问答》等,并且探究文献撰写背景、内容及其价值。梵蒂冈收藏的珍贵稿抄本天主教文献,对中国明清史、中国基督教史以及中西文化交流史的研究均有重要价值。

关键词：黎玉范《圣教孝亲解》汉西双语词典《拜客问答》

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Research on Test Method of Platinum Loading in Fuel Cell Membrane Electrode

Research on Test Method of Platinum Loading in Fuel Cell Mem...

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2023中国汽车工程学会年会暨展览会

作者： Yao Hui Zhang Zhongrong Li Minghe yang huiling CATARC Automotive Test Center(Tianjin)Co. Ltd.

As the energy conversion unit of proton exchange membrane fuel cell(PEMFC),membrane electrode assembly(MEA)converted chemical energy into electrical energy under the action of ***-based catalyst was still an irreplaceable catalyst for commercial PEMFC,and the platinum(Pt) loading in membr ane electrode had became an important indicator of PEMFC performance *** improving the existing national standard method for testing the platinum loading of PEMFC membrane electrode,a microwave digestion pretreatment method for testing the platinum loading of PEMFC membrane electrode was *** with the national standard method,the new method not only improved the accuracy of the test results,but also greatly improved the test *** amount of reagent was greatly *** method was more green,safe and environmentally friendly.

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著作权滥用的反垄断法控制研究

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现代经济探讨 2009年第2期 24-27页

作者：杨惠玲南京大学副编审南京210093

改革开放以来,中国著作权法律保护取得了举世瞩目的成就。但是,著作权保护必须有一个合理的界限。著作权的专有性或法定垄断性决定了著作权滥用往往会涉及限制竞争问题。为防止著作权的滥用,著作权的行使必须受到相应的以反垄断法为中... 详细信息

改革开放以来,中国著作权法律保护取得了举世瞩目的成就。但是,著作权保护必须有一个合理的界限。著作权的专有性或法定垄断性决定了著作权滥用往往会涉及限制竞争问题。为防止著作权的滥用,著作权的行使必须受到相应的以反垄断法为中心的法律控制。因此,积极借鉴外国经验,构建我国著作权滥用反垄断法控制体系对促进我国经济发展意义重大。

关键词：著作权滥用反垄断法权利滥用反垄断法控制

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