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Design, performance and application of a line-imaging velocity interferometer system for any reflector coupled with a streaked optical pyrometer system at the Shenguang-Ⅱ upgrade laser facility

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High Power Laser Science and Engineering 2024年第1期12卷 52-59页

作者： Dawei Yuan Shaojun Wang huigang wei Haochen Gu Yu Dai Jiayong Zhong Yutong Li Gang Zhao Jie Zhang Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijingChina Institute of Frontiers in Astronomy and Astrophysics of Beijing Normal University BeijingChina Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijingChina Key Laboratory for Laser Plasmas(MOE)and School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Department of Astronomy Beijing Normal UniversityBeijingChina Collaborative Innovation Center of IFSA Shanghai Jiao Tong UniversityShanghaiChina School of Physical Sciences University of Chinese Academy of SciencesBeijingChina Songshan Lake Materials Laboratory DongguanChina

The velocity interferometer system for any reflector(VISAR) coupled with a streaked optical pyrometer(SOP) system is used as a diagnostic tool in inertial confinement fusion(ICF) experiments involving equations of state and shock *** validate the process of adiabatically compressing the fuel shell through precise tuning of shocks in experimental campaigns for the double-cone ignition(DCI) scheme of ICF, a compact line-imaging VISAR with an SOP system is designed and implemented at the Shenguang-II upgrade laser facility. The temporal and spatial resolutions of the system are better than 30 ps and 7 μm, respectively. An illumination lens is used to adjust the lighting spot size matching with the target size. A polarization beam splitter and λ/4 waveplate are used to increase the transmission efficiency of our system. The VISAR and SOP work at 660 and 450 nm, respectively, to differentiate the signals from the scattered lights of the drive lasers. The VISAR can measure the shock velocity. At the same time, the SOP system can give the shock timing and relative strength. This system has been used in different DCI campaigns, where the generation and propagation processes of multi-shock are carefully diagnosed.

关键词： double-cone ignition streaked optical pyrometer velocity interferometer system for any reflector

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FGF21-mediated autophagy:Remodeling the homeostasis in response to stress in liver diseases

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Genes & Diseases 2024年第3期11卷 264-274页

作者： wei Shen Modan Yang Hao Chen Chiy He huigang Li Xinyu Yang Jianyong Zhuo Zuyuan Lin Zhihang Hu Di Lu Xiao Xu Zhejiang University School of Medicine HangzhouZhejiang 310058China Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Department of Hepatobiliary and Pancreatic SurgeryAffiliated Hangzhou First People's HospitalZhejiang University School of MedicineHangzhouZhejiang 310006China The Institute for Organ Repair and Regenerative Medicine of Hangzhou HangzhouZhejiang 310006China Institute of Organ Transplantation Zhejiang UniversityHangzhouZhejiang 310003China National Center for Healthcare Quality Management in Liver Transplant HangzhouZhejiang 310003China

Liver diseases are worldwide problems closely associated with various stresses,such as endoplasmic reticulum *** exact interplay between stress and liver diseases remains *** plays an essential role in maintaining homeostasis,and recent studies indicate tight crosstalk between stress and autophagy in liver *** the bal-ance between damage and autophagy is broken,autophagy can no longer resist injury or main-tain *** recent years,FGF21(fibroblast growth factor 21)-induced autophagy has attracted much ***21 is regarded as a stress hormone and can be up-regulated by an abundance of signaling pathways in response to ***,increased FGF21 activates autophagy by a complicated signaling network in which mTOR plays a pivotal *** review summarizes the mechanism of FGF21-mediated autophagy and its derived application in the defense of stress in liver diseases and offers a glimpse into its promising prospect in future clinical practice.

关键词： Autophagy Fibroblast growth factor 21 Liver diseases mTOR Stress

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Physical parameter estimation with MCMC from observations of Vela X-1

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High Power Laser Science and Engineering 2018年第2期6卷 202-212页

作者： Lan Zhang Feilu Wang Xiangxiang Xue Dawei Yuan huigang wei Gang Zhao Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100012China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 101408China Graduate School of China Academy of Engineering Physics Beijing 100196China

We present a parameter estimate for continua, and He-like triplets of the high resolution X-ray spectra with a Bayesian inference and a Markov Chain Monte Carlo(MCMC) tool. The method is applied for Vela X-1 with three different orbital phases(φ), Eclipse, φ = 0.25, and φ = 0.5, which are adopted from the Chandra High-Energy Transmission Grating Spectrometer(HETGS). A parameterized two-component power-law model [Sako et al., Astrophys. J. 525, 921(1999)] and a multi-Gaussian model are applied to model these continua and He-like triplets, respectively. A uniform distribution over each parameter is used as the prior belief. Posterior probability distribution functions of parameters and the covariances among them are explored by using the MCMC method. The main advantages are(i) all model-based parameters are set to be free instead of artificially fixing some of the parameters during the data-model fitting;(ii) the contributions from satellite lines are considered;(iii) backgrounds are treated as a correction to the observation errors;and(iv) the confidence interval of each parameter is given. The fitted results show that the column density of scatter component(N_H^(scat)) varies from phase to phase, which imply a non-spherical structure of the stellar wind in Vela ***, the wind velocities derived from main lines of each set of He-like triplets show better self-consistency than those in previous publications, which could provide a reliable approach for the diagnostics of photoionized plasma in astrophysical objects and the laboratory.

关键词： data analysis satellite lines X-ray spectra

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Observation of Zeeman splitting effect in a laser-driven coil

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Matter and Radiation at Extremes 2022年第2期7卷 18-24页

作者： Baojun Zhu Zhe Zhang Chang Liu Dawei Yuan weiman Jiang huigang wei Fang Li Yihang Zhang Bo Han Lei Cheng Shangqing Li Jiayong Zhong Xiaoxia Yuan Bowei Tong wei Sun Zhiheng Fang Chen Wang Zhiyong Xie Neng Hua Rong Wu Zhanfeng Qiao Guiyun Liang Baoqiang Zhu Jianqiang Zhu Shinsuke Fujioka Yutong Li Beijing National Laboratory of Condensed Matter Physics Institute of PhysicsCASBeijing 100190China Institute of Laser Engineering Osaka University2-6 Yamada-okaSuitaOsakaJapan Songshan Lake Materials Laboratory DongguanGuangdong 523808China Department of Advanced Photon Research Kansai Photon Science InstituteNational Institutes for Quantum and Radiological Science and Technology619-0215 KyotoJapan Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Department of Astronomy Beijing Normal UniversityBeijing 100875China Center for Advanced Material Diagnostic Technology College of Engineering PhysicsShenzhen Technology UniversityShenzhen 518118China Shanghai Institute of Laser Plasma Shanghai 201800China National Laboratory on High Power Laser and Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China

The Zeeman splitting effect is observed in a strong magnetic field generated by a laser-driven *** expanding plasma from the coil wire surface is concentrated at the coil center and interacts with the simultaneously generated magnetic *** Cu I spectral lines at wavelengths of 510.5541,515.3235,and 521.8202 nm are detected and *** splittings of spectral lines are used to estimate the magnetic field strength at the coil center as∼31.4±15.7 T at a laser intensity of∼5.6310^(15) W/cm^(2),which agrees well with measurements using a B-dot *** other plasma parameters of the central plasma disk are also *** temperature is evaluated from the Cu I spectral line intensity ratio,while the electron density is estimated from the Stark broadening effect.

关键词： laser splitting effect

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Gas-phase synthesis of Ti_(2)CCl_(2) enables an efficient catalyst for lithiumsulfur batteries

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The Innovation 2024年第1期5卷 33-40页

作者： Maoqiao Xiang Zihan Shen Jie Zheng Miao Song Qiya He Yafeng Yang Jiuyi Zhu Yuqi Geng Fen Yue Qinghua Dong Yu Ge Rui Wang Jiake wei weiliang Wang Haiming Huang huigang Zhang Qingshan Zhu Chuanfang John Zhang State Key Laboratory of Multiphase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of the Chinese Academy of SciencesBeijing 100049China Innovation Academy for Green Manufacture Chinese Academy of SciencesBeijing 100190China China Nuclear Power Engineering Co. Ltd.117 West Third Ring RoadNorth SectionBeijing 100840China College of Materials Science&Engineering Sichuan UniversityChengdu 610065China State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China School of Physics Guangdong Province Key Laboratory of Display Material and TechnologyCenter for Neutron Science and TechnologySun Yat-sen UniversityGuangzhou 510275China Solid State Physics&Material Research Laboratory School of Physics and Materials ScienceGuangzhou UniversityGuangzhou 510006China

MXenes have aroused intensive enthusiasm because of their exotic properties and promising ***,to date,they are usually synthesized by etching *** synthetic technologies provides more opportunities for innovation and may extend unexplored ***,we report a bottom-up gas-phase synthesis of Cl-terminated MXene(Ti_(2)CCl_(2)).The gas-phase synthesis endows Ti_(2)CCl_(2) with unique surface chemistry,high phase purity,and excellent metallic conductivity,which can be used to accelerate polysulfide conversion kinetics and dramatically prolong the cyclability of Li-S ***-depth mechanistic analysis deciphers the origin of the formation of Ti_(2)CCl_(2) and offers a paradigm for tuning MXene chemical vapor *** brief,the gas-phase synthesis transforms the synthesis of MXenes and unlocks the hardly achieved potentials of MXenes.

关键词： synthesis phase lithium

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Generation of strong magnetic fields with a laser-driven coil

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High Power Laser Science and Engineering 2018年第3期6卷 1-8页

作者： Zhe Zhang Baojun Zhu Yutong Li weiman Jiang Dawei Yuan huigang wei Guiyun Liang Feilu Wang Gang Zhao Jiayong Zhong Bo Han Neng Hua Baoqiang Zhu Jianqiang Zhu Chen Wang Zhiheng Fang Jie Zhang Beijing National Laboratory of Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100190 China School of Physical Sciences University of Chinese Academy of Sciences Beijing 100049 China Collaborative Innovation Center oflFSA (CICIFSA) Shanghai Jiao Tong University Shanghai 200240 China Key Laboratory of Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China Department of Astronomy Beijing Normal University Beijing 100875 China National Laboratory on High Power Laser and Physics Chinese Academy of Sciences Shanghai 201800 China Shanghai Institute of Laser Plasma Shanghai 201800 China Key Laboratory for Laser Plasmas (MoE) and Department of Physics and Astronomy Shanghai Jiao Tong University Shanghai 200240 China

As a promising new way to generate a controllable strong magnetic field, laser-driven magnetic coils have attracted interest in many research fields. In 2013, a kilotesla level magnetic field was achieved at the Gekko XⅡ laser facility with a capacitor–coil target. A similar approach has been adopted in a number of laboratories, with a variety of targets of different shapes. The peak strength of the magnetic field varies from a few tesla to kilotesla, with different spatiotemporal ranges. The differences are determined by the target geometry and the parameters of the incident laser. Here we present a review of the results of recent experimental studies of laser-driven magnetic field generation, as well as a discussion of the diagnostic techniques required for such rapidly changing magnetic fields. As an extension of the magnetic field generation, some applications are discussed.

关键词：激光驱动磁线圈激光技术发展现状技术创新

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电子束离子阱对中性气体电荷交换的光谱诊断

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强激光与粒子束 2018年第12期30卷 27-33页

作者：梁雅琼梁贵云魏会冈北京物资学院物流学院北京101149 中国科学院国家天文台北京100012

在实验室天体物理研究中,电子束离子阱(EBIT)是极端紫外(EUV)和X射线波段能谱分析的重要实验平台,其中EBIT中心残余的中性气体对离子产生存在显著影响。研究了阱区中心残余中性气体对电荷态分布的影响,发现阱区中心残余中性气体和高电... 详细信息

在实验室天体物理研究中,电子束离子阱(EBIT)是极端紫外(EUV)和X射线波段能谱分析的重要实验平台,其中EBIT中心残余的中性气体对离子产生存在显著影响。研究了阱区中心残余中性气体对电荷态分布的影响,发现阱区中心残余中性气体和高电荷态离子之间的电荷/能量交换过程不仅影响离子的电荷分布,而且对激发函数(离子分布比例随电子能量关系曲线)有着极大的影响。利用电离平衡分析方法成功诊断出阱区中心区域残留的中性气体分子数密度,以及内腔室的真空度。

关键词：原子过程电子束离子阱极紫外线

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老年下呼吸道感染铜绿假单胞菌的病原学特征分析

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中国病原生物学杂志 2024年第1期19卷 74-78页

作者：陈惠刚李桂艳马微张家口学院医学院河北张家口075000

目的分析本地区老年下呼吸道感染患者的病原学特征。方法选取2020-2022年张家口学院附属人民医院治疗的286例老年下呼吸道感染患者为研究对象,选取同期住院、年龄≥65岁未发生下呼吸道感染的住院患者为对照组。患者入院后未进行抗菌治疗... 详细信息

目的分析本地区老年下呼吸道感染患者的病原学特征。方法选取2020-2022年张家口学院附属人民医院治疗的286例老年下呼吸道感染患者为研究对象,选取同期住院、年龄≥65岁未发生下呼吸道感染的住院患者为对照组。患者入院后未进行抗菌治疗前,采集清晨第一口痰液,接种不同培养基,培养分离纯化后用全自动细菌鉴定及药敏分析系统进行菌株鉴定及药敏分析,采用聚合酶链反应检测铜绿假单胞菌毒力基因的携带情况。结果286例老年下呼吸道感染患者中,主要为肺炎(49.65%,142/286),检出286株病原菌。212株为革兰阴性菌,主要为肺炎克雷伯菌(22.73%,22/286)和铜绿假单胞菌(14.69%,42/286)。72株为革兰阳性菌(25.17%,72/286),主要为肺炎链球菌(11.89%,34/286)。对革兰阴性菌进行药敏试验,对氨曲南、左氧氟沙星、复方新诺明的耐药率高于50%,分别为50.47%、53.77%和52.36%,对头孢他啶、莫西沙星的耐药率低于30%,分别为29.72%和24.53%,对亚胺培南、美罗培南、阿米卡星耐药率低于10%。对革兰阳性菌进行药敏试验,对青霉素、红霉素、克林霉素、复方新诺明的耐药率高于50%,分别为95.83%、72.22%、61.11%和55.56%,对莫西沙星的耐药率为26.39%,未产生对万古霉素、替考拉宁的耐药株。42株铜绿假单胞菌中,28株携带exoS基因(66.67%,28/42),11株携带exoU基因(26.19%,11/42)。携带exoU基因的铜绿假单胞菌,对环丙沙星、左氧氟沙星、莫西沙星、庆大霉素、阿米卡星的耐药率均高于携带exoS基因的铜绿假单胞菌,携带exoU基因的铜绿假单胞菌对氨曲南的耐药率低于携带exoS基因的铜绿假单胞菌,差异有统计学意义(P0.05)。对比三组患者血清PCT水平,细菌感染组患者高于对照组,革兰阴性菌感染者水平高于革兰阳性菌感染者,差异有统计学意义(F=351.778,P<0.05)。以老年下呼吸道感染病原菌为基准,绘制ROC曲线,血清PCT水平的曲线下面积(AUC)为0.972(95%CI:0.952~0.993),最佳截断值为1.605 ng/mL时,敏感度为95.3%,特异性为100%。结论老年下呼吸道感染患者病原菌主要为革兰阴性菌,对临床常见抗菌药物耐药率较高,exoU基因与铜绿假单胞菌的耐药性显著相关。血清PCT水平可以作为对老年下呼吸道感染的初步筛查指标,对诊断患者感染病原菌类型具有一定临床价值。

关键词：下呼吸道感染病原菌耐药性铜绿假单胞菌毒力基因

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Measurement and analysis of K-shell lines of silicon ions in laser plasmas

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High Power Laser Science and Engineering 2018年第2期6卷 133-140页

作者： Bo Han Feilu Wang Jiayong Zhong Guiyun Liang huigang wei Dawei Yuan Baojun Zhu Fang Li Chang Liu Yanfei Li Jiarui Zhao Zhe Zhang Chen Wang Jun Xiong Guo Jia Neng Hua Jianqiang Zhu Yutong Li Gang Zhao Jie Zhang Department of Astronomy Beijing Normal University Key Laboratory of Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences IFSA Collaborative Innovation Center Shanghai Jiao Tong University National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Research Center for Laser Fusion China Academy of Engineering Physics National Laboratory on High Power Laser and Physics Chinese Academy of Sciences Key Laboratory for Laser Plasmas (MoE) and Department of Physics and Astronomy Shanghai Jiao Tong University

We present laboratory measurement and theoretical analysis of silicon K-shell lines in plasmas produced by Shenguang II laser facility, and discuss the application of line ratios to diagnose the electron density and temperature of laser *** types of shots were carried out to interpret silicon plasma spectra under two conditions, and the spectra from 6.6 ?A to6.85 ?A were measured. The radiative-collisional code based on the flexible atomic code(RCF) is used to identify the lines, and it also well simulates the experimental spectra. Satellite lines, which are populated by dielectron capture and large radiative decay rate, influence the spectrum profile significantly. Because of the blending of lines, the traditional G value and R value are not applicable in diagnosing electron temperature and density of plasma. We take the contribution of satellite lines into the calculation of line ratios of He-α lines, and discuss their relations with the electron temperature and density.

关键词： high energy density physics laser plasmas interaction plasmas astrophysics

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高速开关阀动态响应特性研究及性能优化

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机床与液压 2024年第12期52卷 119-126页

作者：吴会刚韦文术徐龙北京天玛智控科技股份有限公司北京101300

为研究某型高速开关阀的动态响应特性并开展参数优化,描述开关阀的结构组成及工作原理,并建立其数学模型;基于电磁铁的有限元模型,重点研究极靴盆口磁分路的作用,并求解电磁力及磁通量离散空间分布;进而建立开关阀的机-电-液联合仿真模... 详细信息

为研究某型高速开关阀的动态响应特性并开展参数优化,描述开关阀的结构组成及工作原理,并建立其数学模型;基于电磁铁的有限元模型,重点研究极靴盆口磁分路的作用,并求解电磁力及磁通量离散空间分布;进而建立开关阀的机-电-液联合仿真模型,研究其静态压力控制特性及关键参量的动态响应过程。以单变量作用规律分析为基础,应用(1+1)-ES算法完成多参数迭代优化。最后,测定高速开关阀的动态响应特性,完成对比验证。实验结果表明:所建立的联合仿真模型较好地刻画了开关阀的动态响应特性,并借助进化策略优化算法实现了性能的有效提升。

关键词：高速开关阀电磁场有限元方法进化策略参数优化

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