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SDSS spectroscopy for blazars in the Fermi LAT bright AGN sample

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Research in Astronomy and Astrophysics 2009年第11期9卷 1192-1204页

作者： Zhao-Yu Chen min-Feng gu Zhong-hui Fan Xin-Wu Cao Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of Sciences Shanghai 200030 China Graduate University of Chinese Academy of Sciences Beijing 100049 China Department of Physics Yunnan University Kunming 650091 China

We have collected all available spectra and photometric data from the SDSS catalog for bright AGNs complied from the first three months of the Fermi large area telescope all-sky survey. Based on the 106 high-confidence and 11 low-confidence associated bright AGN list, the photometry data are collected from SDSS DR7 for 28 sources （12 BL Lacs and 16 FSRQs）, two of which are low-confidence associated bright AGNs. Among these 28 SDSS photometric sources, SDSS spectra are available for 20 sources （6 BL Lacs and 14 FSRQs）. The black hole masses MBH and the broad line region （BLR） luminosity were obtained for 14 FSRQs by measuring the line-widths and strengths of broad emission lines from the SDSS spectra. The broad emission line measurements of five FSRQs are presented for the first time in this work. The optical continuum emission of these 14 FSRQs is found to be likely dominated by the non-thermal jet emission by comparing the relationship between the broad Mg II line and continuum luminosity to that of radio-quiet AGNs. The black hole mass of the 14 FSRQs ranges from 10^8.2 M⊙ to 10^9.9 M⊙, with most of the sources larger than 10^9 M⊙. The Eddington ratio Lbol/LEdd ranges from 10-1＇5 to - 1. This implies that an optically thin, geometrically thick accretion disk may exist in these FSRQs.

关键词： galaxies active -- galaxies nuclei -- gamma rays observations -- quasars emission lines -- BL Lacertae objects general

Spatial Structure,Hierarchy and Formation Mechanisms of Scientific Collaboration Networks:Evidence of the Belt and Road Regions

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Chinese Geographical Science 2020年第6期30卷 959-975页

作者： gu Weinan LIU hui Institute o f Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China Key Laboratory of Regional Sustainable Development Modelings Chinese Academy of Sciences Beijing 100101China College of Resource and Environment University of Chinese Academy of SciencesBeijing 100049China

Scientific collaboration has become an important part of the people-to-people exchanges in the Belt and Road initiative,and remarkable progress has been made since *** the 65 countries along the Belt and Road(BRI countries)as the research areas and using collaborated Web of Science(WOS)core collection papers to construct an international scientific collaboration matrix,the paper explores the spatial structure,hierarchy and formation mechanisms of scientific collaboration networks of 65 countries along the Belt and *** results show that:1)Beyond the Belt and Road regions(BRI regions),Central&Eastern Europe,China and West Asia&North Africa have formed a situation in which they all have the most external links with other countries beyond BRI *** has the dominant role over other BRI countries in generating scientific *** overall spatial structure has changed to a skeleton structure consisting of many dense regions,such as Europe,North America,East Asia and Oceania.2)Within the Belt and Road regions,Central&Eastern Europe has become the largest collaboration partner with other sub-regions in BRI *** spatial structure of scientific collaboration networks has transformed from the‘dual core’composed of China and the Central&Eastern Europe region,to the‘multi-polarization’composed of‘one zone and multi-points’.3)The hierarchical structure of scientific collaboration networks presents a typical‘core-periphery’structure,and changes from‘single core’to‘double cores’.4)Among the formation mechanisms of scientific collaboration networks,scientific research strength and social proximity play the most important roles,while geographical distance gradually weakens the hindrance to scientific collaboration.

关键词： scientific collaboration networks spatial structure hierarchy formation mechanisms the Belt and Road regions

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卡介菌多糖核酸对CIK细胞活性的影响

湖南师范大学自然科学学报 2017年第2期40卷 33-38页

作者：黄招琴苏壬香钟贝芬韩慧敏谷陟欣颜冬兰辛秀袁莉胡翔湖南师范大学生命科学学院蛋白质化学与基因调控教育部重点实验室中国长沙410081 九芝堂股份有限公司博士后工作站中国长沙410205

在CIK细胞的培养过程中加入卡介菌多糖核酸,研究其对CIK细胞体外增殖及杀瘤活性等方面的影响.CCK-8检测结果发现低浓度卡介菌多糖核酸处理的CIK细胞相比对照组(生理盐水),细胞增殖能力和杀瘤效果都显著上调.RT-qPCR结果显示卡介菌多糖... 详细信息

在CIK细胞的培养过程中加入卡介菌多糖核酸,研究其对CIK细胞体外增殖及杀瘤活性等方面的影响.CCK-8检测结果发现低浓度卡介菌多糖核酸处理的CIK细胞相比对照组(生理盐水),细胞增殖能力和杀瘤效果都显著上调.RT-qPCR结果显示卡介菌多糖核酸处理后的CIK细胞毒活性相关因子(Granzyme B,IFN-γ,TNF-α和TNF-β)mRNA的表达相比对照组都有提高.这些结果可为培养具有更高效杀瘤活性又能大量扩增的CIK细胞提供新思路.

关键词：卡介菌多糖核酸 CIK 细胞增值杀瘤活性

NASTCNN: a spatio-temporal convolutional neural network with non-local attention mechanism for image-induced brain activity pattern recognition

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Optoelectronics Letters 2025年

作者： TAN Xiangxin SHAO mingxiong ZENG Ke gu Yue School of Computer Science and Engineering， Tianjin University of Technology Engineering Research Center of Learning-Based Intelligent System (ministry of Education)， Tianjin University of Technology Krembil Research Institute， University Health Network

Deciphering the brain’s visual processing mechanisms has always been a hot topic. Using neural signal patterns to predict the corresponding external visual stimuli is crucial in understanding the interaction of real visual scenes. There are some challenges in the study of image-induced brain activity pattern recognition based on electroencephalogram (EEG)， e.g. how to fully utilize the effective features of EEG signals to improve the classification， and how the frequency and the length of EEG effect the model performance. We design an experimental paradigm that minimizes the interaction between visual stimuli， and propose a spatio-temporal convolutional neural network with non-local attention mechanism (NASTCNN) for image-induced brain activity pattern recognition. The framework utilizes non-local feature extraction operations to realize global information interaction between EEG signals over long distances and enhance the feature expression of some important information. Our model achieves the best performance on both MNIST-EEG and ImageNet-EEG datasets. The classification results are 24.00% and 50.10% respectively， higher than the random probability. We also analyze the effects of different EEG frequency bands and time subsequences of different lengths on the classification performance and which brain regions are activated over time. The results show that when full frequency band and entire length sequence are selected， the classification result is optimal. The occipital region is essential for processing visual tasks， and the temporal region and some frontal regions also play important role in the later stage of visual decoding. This research can help us better understand the visual processing mechanism of the brain.

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The composite X-ray spectra of radio-loud and radio-quiet SDSS quasars

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Research in Astronomy and Astrophysics 2021年第1期21卷 33-44页

作者： min-Hua Zhou min-Feng gu Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy ofSciences80 Nandan RoadShanghai 200030China University of Chinese Academy of Sciences 19A Yuquan RoadBeijing 100049China

We present a study of the X-ray emission for a sample of radio-detected quasars constructed from the cross-matches between SDSS,FIRST catalogs and XMM-Newton archives.A sample of radio-quiet SDSS quasars without FIRST radio detection is also assembled for *** construct the optical and X-ray composite spectra normalized at rest frame 4215 A(or 2200 A)for both radio-loud quasars(RLQs)and radio-quiet quasars(RQQs)at z≤3.2,with matched X-ray completeness of 19%,redshift and optical *** the optical composite spectrum of RLQs is similar to that of RQQs,we find that RLQs have a higher X-ray composite spectrum than RQQs,consistent with previous studies in the *** dividing the radio-detected quasars into radio loudness bins,we find the X-ray composite spectra are generally higher with increasing radio ***,a significant correlation is found between the optical-to-X-ray spectral index and radio loudness,and there is a unified multi-correlation between the radio and X-ray luminosities and radio loudness in radio-detected *** results could be possibly explained with the corona-jet model,in which the corona and jet are directly related.

关键词： methods:statistical catalogs quasars:general X-rays:general

Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic resonance

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Chinese Chemical Letters 2008年第9期19卷 1108-1110页

作者： hui hui Li gu Yuan Beifing National Laboratory for Molecular Sciences Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education Department of Chemical Biology College of Chemistry and Molecular Engineering Peking University Beifing 100871 China

In this research, an unusually dimeric G-quadruplex of d（GGGTGGGTGGGTGGGT）（SI）, the potent nanomolar HIV-1 integrase inhibitor, was detected by nuclear magnetic resonance （NMR）. This result has been confirmed b... 详细信息

关键词： G-quadruplex HIV-1 integrase inhibitor Nuclear magnetic resonance

Meta-analysis of the success rate of heartbeat recovery in patients with prehospital cardiac arrest in the past 40 years in China

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Military Medical Research 2020年第4期7卷 430-443页

作者： Xiang-min gu Shi-Bin Yao Zhong-Jie He Yong-Gang Wang Zhi-hui Li Tianjin Binhai New Area Center for Disease Control and Prevention Tianjin 300450China Emergency Department Affiliated Hospital of Chifeng CollegeChifeng 024005Inner MongoliaChina The Fourth Medical Center of Chinese PLA General Hospital Beijing 100048China Beijing Platinum Ten minutes Time-effect Emergency Technology Research Academy Beijing 100039China Beijing Chaoyang District Jiangtai Community Health Service Center Beijing 100016China

Background:Systematic evaluation of the successful heartbeat recovery rate(HRR)in patients during the platinum ten minutes after cardiac ***:The databases of CNKI(January 1979–March 2019),Chongqing VIP(January 1989–March 2019),Wanfang(January 1990–March 2019)and Web of Science(January 1900-May 2020)were *** collect the clinical data of patients with cardiac arrest before hospitalization and analyze the cardiopulmonary resuscitation(CPR)at different *** selection and data extraction were carried out by two researchers independently,and the meta package of R software(version 3.61)was used for ***:A total of 116 papers met the inclusion criteria,including 37,181 *** these patients,3367 had their heartbeats successfully *** results showed a high degree of heterogeneity(χ2=6999.21,Pguide 2000,2005,2010,2015 and other versions),the HRR of other versions[0.264(0.176–0.375)]was higher than the International Cardiopulmonary Resuscitation 2005 edition[0.121(0.092–0.158)].(2)The rescue time was divided into the 0 to≤5 min group,the 5 to≤10 min group,the 10 to≤15 min group,and the>15 min *** HRR were 0.417(0.341–0.496),0.143(0.104–0.193),0.049(0.034–0.069),and 0.022(0.009–0.051),*** HRR was higher in the 0 to≤5 min group than in the 5 to≤10 min group,the 10 to≤15 min group and the>15 min *** was no difference between the 10 to≤15 min group and the>15 min group.(3)When the groups were stratified with the cutoff of 10 min,the≤10 min group HRR[0.250(0.202–0.306)]was higher than the>10 min group rate[0.041(0.029–0.057)].(4)The HRR of the telephone guidance group was[0.273(0.227–0.325)]lower than that of the 0 to≤5 min group[0.429(0.347–0.516)]but higher than that of the 5 to≤10 min group,the 1

关键词： Sudden cardiac arrest Cardiopulmonary resuscitation Peri-cardiac arrest period Platinum 10 min Meta-analysis

Transition-layer of coreerim structures andβ→a transformation in SiC ceramics

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Journal of Materiomics 2023年第2期9卷 299-309页

作者： Qing-Qing Shao hui gu Materials Genome Institute School of Materials Science and EngineeringShanghai UniversityShanghai200444China

Similar to Si_(3)N_(4)ceramics,β→a phase transformation in SiC ceramics plays a key role in tailoring the microstructures thus optimizing related *** microstructures are dominated with the core erim structures by AlN-solution,and by EBSD analysis,a-lamellae were revealed as stacking-faults(SF)and twin-boundaries(TB)in b-grains,co-existing with the coreerim structures asα/β→α’/β’transformation by *** structural transformation can proceed much further by gas-pressuresintering than hot-pressing with only RE2O3 agents,while the latter retain a high-density of SF/TB in the metastable b-SiC *** high-angle secondary-electron imaging,nanoscale transition-layer(TL)was observed as an inter-phase to fully separate the core and rim,which is created by a transitory equilibrium in the solutionereprecipitation *** enrichment of AlN or RE in TL demonstrates their segregation to core surface until reaching the super-saturation and before the growth of *** higher AlN or RE solution and after sintering,a shear stress can develop from TL contour to drive the expansion of SF/TB in Martensitic transition,especially under an external isotropic *** combinations ofβ→a transformation,coreerim structures and viscous liquid-phase enable the comprehensive assessment of sintering-microstructure-property-performance relationship of SiC ceramics,as demonstrated for their creep behaviors and fracture toughness.

关键词： SiC ceramics Coreerim structures Transition-layer Martensitic transition Creep behaviors

Forkhead box M1 transcription factor:a novel target for pulmonary arterial hypertension therapy

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World Journal of Pediatrics 2020年第2期16卷 113-119页

作者： Li gu Han-min Liu Department of Pediatric Pneumology West China Second University HospitalSichuan UniversityChengduChina Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University) Ministry of EducationWest China Second University HospitalSichuan UniversityNo.20Section 3Renmin South RoadWuhou DistrictChengduChina

Background Forkhead box M1(FoxM1),a member of forkhead family,plays a key role in carcinogenesis,progression,invasion,metastasis and drug *** on the similarities between cancer and pulmonary arterial hypertension,studies on the roles and mechanisms of FoxM1 in pulmonary arterial hypertension have been *** article aims to review recent advances in the mechanisms of signal transduction associated with FoxM1 in pulmonary arterial *** sources Articles were retrieved from PubMed and MEDLINE published after 1990,including-but not limited to FoxM1 and pulmonary arterial *** FoxM 1 is overexpressed in pulmonary artery smooth muscle cells in both pulmonary arterial hypertension patients and animal models,and promotes pulmonary artery smooth muscle cell proliferation and inhibits cell apoptosis via regulating cell cycle *** signaling molecules and pathways,including hypoxia-inducible factors,transforming growth factor-β/Smad,SET domain-containing 3/vascular endothelial growth factor,survivin,cell cycle regulatory genes and DNA damage response network,are reported to cross talk with FoxM1 in pulmonary arterial *** inhibitors are effective in the prevention and treatment of pulmonary arterial hypertension by inhibiting the expression and transcriptional activity of *** FoxM1 has a crucial role in the pathogenesis of pulmonary arterial hypertension and may represent a novel therapeutic *** more details of interaction between FoxM1 and other signaling pathways need to be clarified in the future.

关键词： Forkhead box M1 Proteasome inhibitor Pulmonary arterial hypertension Signaling pathway