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High-solid anaerobic digestion of sewage sludge:achievements and perspectives

Frontiers of Environmental Science & Engineering 2021年第4期15卷 1-18页

作者： Ying Xu hui gong Xiaohu Dai State Key Laboratory of Pollution Control and Resource Reuse School of Environmental Science and EngineeringTongji UniversityShanghai200092China Shanghai Institute of Pollution Control and Ecological Security Shanghai200092China

High-solid anaerobic digestion(HS-AD)has been applied extensively during the last few decades for treating various organic wastes,such as agricultural wastes,organic fractions of municipal solid wastes,and kitchen ***,the application of HS-AD to the processing of sewage sludge(SS)remains limited,which is largely attributable to its poor process stability and *** research has been conducted to attempt to surmount these *** this review,the main factors affecting process stability and performance in the HS-AD of SS are comprehensively reviewed,and the improved methods in current use,such as HS sludge pre-treatment and anaerobic co-digestion with other organic wastes,are ***,this paper also discusses the characteristics of substance transformation in the HS-AD of SS with and without thermal *** has shown that the HS effect is due to the presence of high concentrations of substances that may inhibit the function of anaerobic microorganisms,and that it also results in poor mass transfer,a low diffusion coefficient,and high ***,knowledge gaps in the current research on HS-AD of SS are *** on these,it proposes that future efforts should be devoted to standardising the definition of HS sludge,revealing the law of migration and transformation of pollutants,describing the metabolic pathways by which specific substances are degraded,and establishing accurate mathematical ***,developing green sludge dewatering agents,obtaining high value-added products,and revealing effects of the above two on HS-AD of SS can also be considered in future.

关键词： High-solid effect Anaerobic fermentation Methane production Biodegradability Sludge treatment

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Aerobic granular sludge formation based on substrate availability:Effects of flow pattern and fermentation pretreatment

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Frontiers of Environmental Science & Engineering 2020年第3期14卷 155-164页

作者： Quan Yuan hui gong Hao Xi Kaijun Wang State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China

The influences of flow patterns(mixed-flow and plug-flow)and fermentation pretreatment on aerobic granular sludge(AGS)formation with various substrate availability levels were investigated by running four identical laboratory-scale sequencing batch reactors(R1-R4),comparing two anaerobic feeding strategies and three kinds of substrates.R1 achieved faster granulation with a fast influent fill step followed by a modified anaerobic mixed-flow phase,but the AGS showed poorer stability with a cracked structure and a high suspended solids concentration in the *** anaerobic plug-flow feeding mode(with influent fed slowly from the bottom)in R2 provided deeper penetration depth for the substance to reach the core of A G S and accordingly strengthen A G S *** acidogenic upflow sludge bed reactor was introduced as a pretreatment to improve the AGS performance by enhancing glucose pre-fermentation(R4).AGS fed with mixed volatile fatty acids(VFA)after glucose fermentation showed similar performance compared with the reactor fed with acetate in the aspects of stability,structure,size distribution and nitrogen removal efficiency,and 74%similarity in the microbial *** actual wastewater with low VFA concentrations,fermentation treatment was suggested as a promising pretreatment for stable AGS granulation and operation.

关键词： Anaerobic plug-flow feeding mode Anaerobic mixed-flow mode Fermentation pretreatment Substrate gradient Penetration depth

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Whole-brain Optical Imaging:A Powerful Tool for Precise Brain Mapping at the Mesoscopic Level

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Neuroscience Bulletin 2023年第12期39卷 1840-1858页

作者： Tao Jiang hui gong Jing Yuan Huazhong University of Science and Technology-Suzhou Institute for Brainsmatics Jiangsu Industrial Technology Research InstituteSuzhou215123China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan430074China

The mammalian brain is a highly complex network that consists of millions to billions of densely-interconnected *** dissection of neural circuits at the mesoscopic level can provide important structural information for understanding the *** approaches can achieve submicron lateral resolution and achieve“optical sectioning”by a variety of means,which has the natural advantage of allowing the observation of neural circuits at the mesoscopic *** whole-brain optical imaging methods based on tissue clearing or histological sectioning surpass the limitation of optical imaging depth in biological tissues and can provide delicate structural information in a large volume of *** with various fluorescent labeling techniques,whole-brain optical imaging methods have shown great potential in the brain-wide quantitative profiling of cells,circuits,and blood *** this review,we summarize the principles and implementations of various whole-brain optical imaging methods and provide some concepts regarding their future development.

关键词： Whole-brain optical imaging Optical sectioning Micrometer resolution Brain connectome Neural circuits Neuron

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One-pot Two-Step Cycloaddition Reaction for Convenient Synthesis of Polycyclic Spirooxindole-fused [1,3]Oxazines

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Chinese Journal of Chemistry 2015年第9期33卷 1049-1056页

作者： Jing Sun hui gong Chaoguo Yan College of Chemistry & Chemical Engineering Yangzhou University Yangzhou Jiangsu 225002 China

The novel spirooxindoline fused [1,3]oxazines were efficiently synthesized from Diels-Alder reaction of N-arylmaleimides with 1,2-dihydro-2-oxospiro[3H-indole-3,2＇-[2H,9aH-pyrido[2,1-b][l,3]oxazines], which were generated in situ from three-component reactions of substituted pyridines and isatins with methyl propiolate, or di- methyl acetylenedicarboxylate. The stereochemistry of the products was clearly clarified by the analysis of 1H NMR data and single crystal structures of the obtained polycyclic compounds.

关键词： Diels-Alder reaction one-pot reaction diastereoselectivity spirooxindole oxazine maleimide

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A SIMPLE METHOD FOR PREDICTION OF THE REDUCED SCATTERING COEFFICIENT IN TISSUE-SIMULATING PHANTOMS

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Journal of Innovative Optical Health Sciences 2010年第1期3卷 53-59页

作者： JIANWEI FU GUOTAO QUAN hui gong Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics—Huazhong University of Science and Technology Wuhan 430074P.R.China

This paper proposes a method for predicting the reduced scattering coefficients of tissuesimulating phantoms or the desired amount of scatters for producing phantoms according to Mie scattering theory without measurements with other *** concentration of the scatters TiO2 particles is determined according to Mie theory calculation and added to transparent host epoxy resin to produce phantoms with different reduced scattering *** India Ink is added to alter the absorption coefficients of the *** reduced scattering coefficients of phantoms are measured with single integrating sphere *** results show that the measurements are in direct proportion to the concentration of TiO2 and have identical with Mie theory calculation at multiple *** method proposed can accurately determine the concentration of scatters in the phantoms to ensure the phantoms are qualified with desired reduced scattering coefficients at specified *** investigation should be possible to manufacture the phantom simply in reasonably accurate for evaluation of biomedical optical imaging systems.

关键词： Mie scattering theory integrating sphere optical imaging

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Metagenomics reveals the microbial community and functional metabolism variation in the partial nitritation-anammox process:From collapse to recovery

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Journal of Environmental Sciences 2024年第1期135卷 210-221页

作者： Hong Wang hui gong Xiaohu Dai Min Yang State Key Laboratory of Pollution Control and Resource Reuse College of Environmental Science and EngineeringTongji UniversityShanghai 200092China BIOMATH Department of Data Analysis and Mathematical ModellingGhent UniversityGhent 9000Belgium

Mainstream partial nitritation-anammox(PNA)process easily suffers from performance instability and even reactor collapse in ***,it is of great significance to unveil the characteristic of performance recovery,understand the intrinsic mechanism and then propose operational *** this study,we combined long-term reactor operation,batch tests,and metagenomics to reveal the succession of microbial community and functional metabolism variation from system collapse to *** aeration control(0.10-0.25mg O_(2)/L)was critical for performance *** was also found that Candidatus Brocadia became the dominant flora and its abundance increased from 3.5%to 11.0%.Significant enhancements in carbon metabolism and phospholipid biosynthesis were observed during system recovery,and the genes abundance related to signal transduction was dramatically *** up-regulation of sdh and suc genes showed the processes of succinate dehydrogenation and succinyl-CoA synthesis might stimulate the production of amino acids and the synthesis of proteins,thereby possibly improving the activity and abundance of AnAOB,which was conducive to the performance ***,the increase in abundance of hzs and hdh genes suggested the enhancement of the anammox *** in the abundance of key genes involved in nitrogen metabolism indicated that nitrogen removal pathway was more diverse after system *** achievement of performance recovery was driven by anammox,nitrification and denitrification coupled with dissimilatory nitrate reduction to *** results provide deeper insights into the recovery mechanism of PNA system and also provide a potential regulation strategy for the stable operation of the mainstream PNA process.

关键词： Partial nitritation-anammox Metagenomics Microbial community Functional metabolism Recovery

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Constructing the rodent stereotaxic brain atlas:a survey

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Science China(Life Sciences) 2022年第1期65卷 93-106页

作者： Zhao Feng Anan Li hui gong Qingming Luo Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for OptoelectronicsMOE Key Laboratory for Biomedical PhotonicsHuazhong University of Science and TechnologyWuhan 430074China HUST-Suzhou Institute for Brainsmatics Suzhou 215123China School of Biomedical Engineering Hainan UniversityHaikou 570228China

The stereotaxic brain atlas is a fundamental reference tool commonly used in the field of *** we provide a brief history of brain atlas development and clarify three key conceptual elements of stereotaxic brain atlasing:brain image,atlas,and *** also refine four technical indices for evaluating the construction of atlases:the quality of staining and labeling,the granularity of delineation,spatial resolution,and the precision of spatial location and ***,we discuss state-of-the-art technologies and their trends in the fields of image acquisition,stereotaxic coordinate construction,image processing,anatomical structure recognition,and publishing:the procedures of brain atlas *** believe that the use of single-cell resolution and micron-level location precision will become a future trend in the study of the stereotaxic brain atlas,which will greatly benefit the development of neuroscience.

关键词： brain atlas stereotaxic cytoarchitecture brainsmatics

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A Whole-brain Map of Long-range Inputs to GABAergic Interneurons in the Mouse Caudal Forelimb Area

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Neuroscience Bulletin 2020年第5期36卷 493-505页

作者： Zhuonan Duan Anan Li hui gong Xiangning Li Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and TechnologyWuhan 430074China Ministry of Education Key Laboratory for Biomedical Photonics School of Engineering SciencesHuazhong University of Science and TechnologyWuhan 430074China Huazhong University of Science and Technology-Suzhou Institute for Brainsmatics Suzhou 215125China

The caudal forelimb area(CFA)of the mouse cortex is essential in many forelimb movements,and diverse types of GABAergic interneuron in the CFA are distinct in the mediation of cortical inhibition in motor information ***,their long-range inputs remain *** the present study,we combined the monosynaptic rabies virus system with Cre driver mouse lines to generate a whole-brain map of the inputs to three major inhibitory interneuron types in the *** discovered that each type was innervated by the same upstream areas,but there were quantitative differences in the inputs from the cortex,thalamus,and *** the locations of the interneurons in two subregions of the CFA,we discovered that their long-range inputs were remarkably different in distribution and *** whole-brain mapping indicates the existence of parallel pathway organization in the forelimb subnetwork and provides insight into the inhibitory processes in forelimb movement to reveal the structural architecture underlying the functions of the CFA.

关键词： Forelimb area Input circuit Interneuron Parvalbumin Somatostatin Vasoactive intestinal peptide

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Optimal bundles for sponsored search auctions via bracketing scheme

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Frontiers of Computer Science 2019年第2期13卷 333-342页

作者： Zheng-Dong XIA Tian-Ming BU Wen-hui gong Shanghai Key Laboratory of Trustworthy Computing East China Normal University Shanghai 200233 China

Sponsored search auction has been recently studied and auctioneer's revenue is an important consideration in probabilistic single-item second-price auctions. Some papers have analyzed the revenue maximization problem on different methods to bundle contexts. In this paper, we propose a more flexible and natural method which is called the bracketing method. We prove that finding a bracketing scheme that maximizes the auctioneer's revenue is strongly NP-hard. Then, a heuristic algorithm is given. Experiments on three test cases show that the revenue of the optimal bracketing scheme is very close to the optimal revenue without any bundling constraint, and the heuristic algorithm performs very well. Finally, we consider a simpler model that for each row in the valuation matrix, the non-zero cells have the same value. We prove that the revenue maximization problem with Kanonymous signaling scheme and cardinality constrained signaling scheme in this simpler model are both NP-hard.

关键词： sponsored search auction revenue maximization bracketing scheme NP-hardness

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Enhanced triallyl isocyanurate(TAIC)degradation through application of an 03/UV process:Performance optimization and degradation pathways

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Frontiers of Environmental Science & Engineering 2020年第4期14卷 103-113页

作者： Yapeng Song hui gong Jianbing Wang Fengmin Chang Kaijun Wang State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China School of Chemical&Environmental Engineering China University of Mining and TechnologyBeijing 100083China

Triallyl isocyanurate(TAIC,C12H15N3O3)has featured in wastewater treatment as a refractory organic compound due to the significant production capability and negative environmental *** degradation was enhanced when an ozone(O3)/ultraviolet(UV)process was applied compared with the application of an independent O3 *** 99%of TAIC could be degraded in 5 min during both processes,the O3/UV process had a 70%mineralization rate that was much higher than that of the independent O3 process(9%)in 30 *** possible degradation pathways were proposed based on the organic compounds of intermediate products identified during TAIC degradation through the application of independent 03 and O3/UV *** impacted both the direct and indirect oxidation *** and alkaline conditions preferred direct and indirect reactions respectively,with a pH of 9 achieving maximum Total Organic Carbon(TOC)*** CO32-and HCO3-decreased TOC removal,however only CO32-negatively impacted TAIC *** of Cl-as a radical scavenger became more marked only at high concentrations(over 500 mg/L Cl-).Particulate and suspended matter could hinder the transmission of ultraviolet light and reduce the production of HO·accordingly.

关键词： Triallyl isocyanurate O3/UV Advanced oxidation processes(AOP) Degradation pathway

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