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Performance of Gas-Steam Combined Cycle Cogeneration Units Influenced by Heating Network Terminal Steam Parameters

Energy Engineering 2024年第6期121卷 1495-1519页

作者： Guanglu Xie Zhimin Xue Bo Xiong Yaowen huang Chaoming Chen Qing Liao Cheng Yang Xiaoqian Ma zhongshan Jiaming Electric Power Co. Ltd.CNOOC Gas&Power GroupZhongshan528403China School of Electric Power South China University of TechnologyGuangzhou510640China

The determination of source-side extracted heating parameters is of great significance to the economic operation of cogeneration *** paper investigated the coupling performance of a cogeneration heating and power system multidimensionally based on the operating characteristics of the cogeneration units,the hydraulic and thermodynamic characteristics of the heating network,and the energy *** a steam network supported by a gas-steam combined cycle cogeneration system as the research case,the interaction effect among the source-side prime movers,the heating networks,and the terminal demand thermal parameters were investigated based on the designed values,the plant testing data,and the validated *** operating maps of the gas-steam combined cycle cogeneration units were obtained using THERMOFLEX,and the minimum source-side steam parameters of the steam network were solved using an inverse solution procedure based on the hydro-thermodynamic coupling *** cogeneration operating maps indicate that the available operating domain considerably narrows with the rise of the extraction steam pressure and flow *** heating network inverse solution demonstrates that the source-side steam pressure and temperature can be optimized from the originally designed 1.11 MPa and 238.8°C to 1.074 MPa and 191.15°C,*** the operating strategy with the minimum source-side heating parameters,the power peak regulation depth remarkably increases to 18.30%whereas the comprehensive thermal efficiency *** operation under the minimum source-side heating steam parameters can be superior to the originally designed one in the economy at a higher price of the heating *** a fuel price of$0.38/kg and the power to fuel price of 0.18 kg/(kW·h),the critical price ratio of heating steam to fuel is 119.1 kg/*** influence of the power-fuel price ratio on the economic deviation appears relatively weak.

关键词： Gas-steam combined cycle cogeneration of heating and power steam network inverse problem operating performance

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Enhanced Damping Capacities of Mg–Ce Alloy by the Special Microstructure with Parallel Second Phase

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Journal of Materials Science & Technology 2017年第9期33卷 941-946页

作者： zhongshan Wu Jingfeng Wang Haibo Wang She Ma Song huang Shun Li Fusheng Pan National Engineering Research Center for Magnesium Alloys College of Materials Science and EngineeringChongqing University The State Key Laboratory of Mechanical Transmission Chongqing University Institute of Applied Electronics China Academy of Engineering Physics

Microstructure evolution and damping capacities of Mg–Ce binary alloys with three different Ce contents（0.5, 1, or 2 wt%） have been systematically investigated in this work. Numerous fine parallel second phases in Mg–2Ce alloy are obtained, as well as a large number of dislocations around them, but few dislocations appear around the reticular second phase in the Mg–1Ce alloy. Among the three alloys, two internal friction peaks（P;and P;） are detected at about 78 and 167?C in both the Mg–0.5Ce and Mg–1Ce *** addition, the alloy with special parallel second phase structure exhibits excellent damping capacity in both strain amplitude and temperature-dependent regions. These results may be ascribed to the stress concentration and the formation of abundant parallel and uniform dislocation configurations in the ?-Mg matrix without the influence of crystal orientation. The obtained results may provide a novel idea to prepare high-damping magnesium alloys by tailoring their microstructure.

关键词： Mg–Ce alloy Parallel second phase Dislocation configuration Damping capacity

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Beneficial Effects of Traditional Chinese Medicine Fuzheng Huayu on the Occurrence of Hepatocellular Carcinoma in Patients with Compensated Chronic Hepatitis B Cirrhosis Receiving Entecavir:A Multicenter Retrospective Cohort Study

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Journal of Clinical and Translational Hepatology 2024年第5期12卷 505-515页

作者： Haina Fan Shujuan Lei Zhimin Zhao Yan huang Hui Wang Xudong Liu Xiaodong Li Min Xu Wei Zhang Kewei Sun Huichun Xing Yang Mei Jiaquan huang Chuanwu Zhu Kejun Zhang Yali Zong Xizhong Shen Qing Xie Chenghai Liu Institute of Liver Diseases Shanghai Key Laboratory of Traditional Chinese Clinical MedicineKey Laboratory of Liver and Kidney Diseases(Ministry of Education)Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Infectious Diseases Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Infectious Diseases Ruikang Hospital Affiliated to Guangxi University of Chinese MedicineNanningGuangxiChina Institute of Liver Diseases Hubei Provincial Hospital of Traditional Chinese MedicineWuhanHubeiChina Department of Infectious Diseases Huaian Fourth People’s HospitalHuai’anJiangsuChina Institute of Liver Diseases Shijiazhuang Fifth HospitalShijiazhuangHebeiChina Department of Liver Diseases The First Hospital of Hunan University of Chinese MedicineChangshaHunanChina Center of Hepatology Capital Medical University Affiliated Beijing Ditan HospitalBeijingChina Department of Hepatology The Fifth People’s Hospital of AnyangAnyangHenanChina Department and Institute of Infectious Disease Tongji Hospital of Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubeiChina Department of Hepatology The Fifth People’s Hospital of SuzhouSuzhouJiangsuChina Department of Gastroenterology The First People’s Hospital of JingmenJingmenHubeiChina Department of Integrated Traditional and Western Medicine The Ninth Hospital of NanchangNanchangJiangxiChina Department of Gastroenterology Zhongshan HospitalFudan UniversityShanghaiChina

Background and Aims:The application of antifibrotic drugs to treat patients with chronic liver diseases who are receiving antiviral therapies for hepatocellular carcinoma(HCC)has not been ***,we aimed to assess the impact of the Traditional Chinese Medicine Fuzheng Huayu(FZHY)on the occurrence of HCC in patients with hepatitis B virus-related compensated cirrhosis receiving the antiviral drug entecavir(ETV).Methods:A multicenter retrospective cohort study was *** liver cirrhosis patients were divided into the ETV+FZHY group or the ETV group according to *** cumulative incidence of HCC was analyzed using Kaplan-Meier and log-rank *** score matching was used for confounding *** analysis and Cox regression were used to determine the effects of FZHY on the occurrence of HCC and liver function ***:Out of 910 chronic hepatitis B patients,458 were in the ETV+FZHY group and 452 were in the ETV *** propensity score matching,the 5-year cumulative incidence of HCC was 9.8%in the ETV+FZHY group and 21.8%in the ETV group(p36 ***,diabetes,alanine aminotransferase,􀇄-glutamyl transpeptidase,albumin,hepatitis B e-antigen,and fibrosis 4 score were associated with the occurrence of *** decreased the risk of HCC in patients aged>45 years with a hepatitis B virus DNA level of􀂕2,000 IU/***:Adjunctive FZHY treatment reduced HCC occurrence in patients with hepatitis B virus cirrhosis who were treated with ETV,possibly due to the antifibrotic properties of FZHY.

关键词： Entecavir Fuzheng Huayu Hepatitis B virus Cirrhosis Hepatocellular carcinoma Traditional Chinese Medicine

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A novel mouse model of PEDF-associated serious liver inflammation,hepatic tumorigenesis and cardiovascular injury mimics human nonalcoholic steatohepatitis

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Genes & Diseases 2024年第1期11卷 11-14页

作者： Xinghui Li Haiping Wang Yandi Wu Li Zou Shijie Dengg Xintu Fu Tongsheng huang Conghui Shen Teng Wu Weibin Cai Guangdong Engineering&Technology Research Center for Disease-Model Animals Laboratory Animal CenterZhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong 510080China Department of Biochemistry Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong 510080China School of Pharmacy Guangdong Pharmaceutical UniversityGuangzhouGuangdong 510006China Guangdong Provincial Key Laboratory of Digestive Cancer Research The Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhenGuangdong 518107China

There are no approvedtherapeuticdrugs for nonalcoholic steatohepatitis(NASH)due to the many bottlenecks,including the lack of preclinical animal models that can perfectly mimic human NASH features,such as systemic metabolic disorders,hepatic steatosis,intense liver inflammation and fibrosis,liver tumorigenesis,and cardiovascularcomplications.i,2"Pigment"epitheliumderived factor(PEDF)is a lipid metabolism regulator with high expression in the liver,and its reduced expression in the liver is closely related to the development of nonalcoholic fatty liver disease(NAFLD).

关键词： inflammation PEDF hepatic

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Synthesis of ordered mesoporous carbonaceous materials and their highly efficient capture of uranium from solutions

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Science China Chemistry 2018年第3期61卷 281-293页

作者： Chenlu Zhang Xing Li zhongshan Chen Tao Wen Shuyi huang Tasawar Hayat Ahmed Alsaedi Xiangke Wang College of Environmental Science and Engineering North China Electric Power University NAAM Research Group Faculty of Science King Abdulaziz University Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions School for Radiological and Interdisciplinary Sciences Soochow University

An extremely effortless method was applied for successful synthesis of mesoporous carbonaceous materials(MCMs) using well-ordered mesoporous silica as template. Various characterizations(scanning electron microscopy(SEM), transmission electron microscopy(TEM), X-ray diffraction(XRD), Fourier transform infrared spectroscopy(FT-IR), Raman, X-ray photoelectron spectroscopy(XPS), Brunner-Emmet-Teller(BET) and Zeta potential) confirmed that MCMs had large surface area, uniform pore size distribution, and abundant oxygen-containing functional groups. The batch techniques were employed to study U(VI) adsorption on MCMs under a wide range of experiment conditions. The adsorption kinetics of U(VI) onto MCMs were well-fitted by pseudo-second-order kinetic model, indicating a chemisorption process. The excellent adsorption capacity of MCMs calculated from the Langmuir model was 293.95 mg g^(-1) at pH 4.0. The FT-IR and XPS analyses further evidenced that the binding of U(VI) onto MCMs was ascribed to the plentiful adsorption sites(–OH and –COOH groups) in the internal mesoporous structure, which could efficiently trap guest U(VI) ions. The results presented herein revealed that MCMs were ideal adsorbents in the efficient elimination of uranium or other lanthanides/actinides from aqueous solutions, which would play an important role in environmental pollution management application.

关键词： mesoporous carbonaceous materials (MCMs) U(VI) adsorption -OH and -COOH groups

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Oral nanoparticles containing naringenin suppress atherosclerotic progression by targeting delivery to plaque macrophages

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Nano Research 2023年第1期16卷 925-937页

作者： Mengran Guo zhongshan He Zhaohui Jin Lingjing huang Jingmei Yuan Shugang Qin Xinchun Wang Lili Cao Xiangrong Song Department of Critical Care Medicine Department of Anesthesiology and Translational Neuroscience CenterDepartment of Clinical PharmacyFrontiers Science Center for Disease-related Molecular NetworkState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610000China First Affiliated Hospital of the Medical College Shihezi UniversityShihezi 832008China College of Medicine Chengdu UniversityChengdu 610000China

Atherosclerosis is the main cause of ischemic stroke and myocardial infarction *** have shown unique benefits for atherosclerosis treatment by targeting the lesional macrophages of ***,most of the nanocarriers are administered intravenously,which is inconvenient and may cause ***,we developed an oral lipid-polymer based nanoparticles(FA-LNPs)decorated with folic acid,which can not only effectively overcome intestinal mucosal-epithelial barrier by increasing the transmembrane transport through intestinal epithelial and the accumulation in Peyer’s patches but also actively target to the aortic plaque sites and accumulate in lesional ***,naringenin(Nrg),one of the antiinflammation drugs,was designed to be the oral nanomedicine(FA-LNPs/Nrg)for the first time via the encapsulation of ***-LNPs/Nrg presented highly anti-atherosclerotic *** the atherosclerotic ApoE−/−mice were treated by FALNPs/Nrg via oral administration for three months,the aortic lesion area,plaque area,and necrotic core area of the aortic root were significantly ***,the lipid-related blood parameters recovered to normal *** study provides a promising approach to atherosclerosis treatment based on the novel oral targeting delivery system.

关键词： atherosclerosis macrophages Peyer’s patches oral delivery folic acid naringenin

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Introgression of lac6/tl1/du13 improves the palatability of japonica rice

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The Crop Journal 2024年第4期12卷 1259-1265页

作者： Yong Yang Tao Zhang Yuliang Shi Yan Lu Qianfeng Li Xiaolei Fan Lichun huang Lu Chen Xuetang Song Qing Liu Changquan Zhang Qiaoquan Liu Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/zhongshan Biological Breeding Laboratory/Key Laboratory of Plant Functional Genomics of the Ministry of Education Agricultural College of Yangzhou UniversityYangzhou 225009JiangsuChina Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops/Jiangsu Key Laboratory of Crop Genetics and Physiology Yangzhou UniversityYangzhou 225009JiangsuChina Jiang Su(Wu Jin)Rice Research Institute Changzhou 213175JiangsuChina

Amylose content(AC)is a crucial determinant of the eating and cooking quality(ECQ)of rice,with low AC varieties exhibiting a softer texture and greater stickiness-attributes that enhance palatability and are desirable in specific culinary *** harness these traits,significant efforts have been made to manipulate AC to improve rice *** research utilized the MutMap+approach to identify LAC6/TL1,a gene that is an allele of Du13,responsible for low ***6 encodes a C2H2 zinc finger protein,which specifically increases the splicing efficiency of the Wxb allele without affecting the Wxa *** studies of LAC6 revealed that its proper integration could rectify the undesirable AC phenotype,whereas mutations within this gene led to reduced AC and were associated with shorter grain length and decreased thousand-grain *** these drawbacks,such mutations positively impact rice palatability,presenting a trade-off between grain size and eating *** address the challenges posed by the reduced grain weight associated with LAC6 mutations,we developed a specific molecular marker for LAC6,which has been effectively used in breeding programs to select lac6/tl1/du13 homozygous individuals with larger grain *** findings demonstrate that the“small grain”trait associated with lac6/tl1/du13 can be effectively mitigated through combined phenotype-based and marker-assisted *** study highlights the potential of lac6/tl1/du13 as a valuable gene for breeding novel,high-quality soft rice varieties through targeted breeding strategies.

关键词： Rice Dull endosperm Amylose content Wx Breeding

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Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis

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Asian Journal of Pharmaceutical Sciences 2024年第3期19卷 131-145页

作者： Rui Wang Tongyao Liu Xinhong Li Enhao Lu Yiting Chen Kuankuan Luo Tao Wang Xueli huang Zhiwen Zhang Shilin Du Xianyi Sha Key Laboratory of Smart Drug Delivery(Ministry of Education) Institutes of Integrative MedicineDepartment of PharmaceuticsSchool of PharmacyFudan UniversityShanghai 201203China Department of Emergency Medicine Shanghai Geriatric Medical CenterShanghai 201104China Department of Emergency Medicine Zhongshan HospitalFudan UniversityShanghai 200032China

Flare and multiple recurrences pose significant challenges in gouty *** treatments provide temporary relief from inflammation but fail to promptly alleviate patient pain or effectively prevent subsequent *** should also be noted that both anti-inflammation and metabolism of uric acid are necessary for gouty arthritis,calling for therapeutic systems to achieve these two goals *** this study,we propose a biomimetic integrated nanozyme,HMPB-Pt@MM,comprising platinum nanozyme and hollow Prussian *** demonstrates anti-inflammatory properties by eliminating reactive oxygen species and reducing infiltration of inflammatory ***,it rapidly targets inflamed ankles through the camouflage of macrophage ***,HMPB-Pt@MM exhibits urate oxidase-like capabilities,continuously metabolizing locally elevated uric acid concentrations,ultimately inhibiting multiple recurrences of gouty *** summary,HMPB-Pt@MM integrates ROS clearance with uric acid metabolism,offering a promising platform for the treatment of gouty arthritis.

关键词： Gouty arthritis Inflammation Nanozyme Platinum Prussian blue

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外泌体在牙周再生应用的研究进展

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实用口腔医学杂志 2024年第1期40卷 117-121页

作者：黄欣悦龚旭郭维维张滋彬公梓昊(综述) 王忠山(审校) 口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔医学重点实验室第四军医大学口腔医院修复科西安710032 口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔医学重点实验室第四军医大学口腔材料学教研室西安710032 口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔医学重点实验室第四军医大学口腔颌面外科西安710032 空军军医大学基础医学院一大队一队

牙周病在中国人群中的患病率高达90%以上,现有治疗技术仅能控制疾病发展,诱导骨组织再生能力成为治疗的希望和难点。外泌体是一类来源于核内体的多囊泡结构物,近年来将其应用于牙周再生领域的研究越来越多。该文将近年来外泌体在牙周再... 详细信息

牙周病在中国人群中的患病率高达90%以上,现有治疗技术仅能控制疾病发展,诱导骨组织再生能力成为治疗的希望和难点。外泌体是一类来源于核内体的多囊泡结构物,近年来将其应用于牙周再生领域的研究越来越多。该文将近年来外泌体在牙周再生领域的应用进行综述,有望为牙周再生治疗提供新的思路。

关键词：外泌体牙周再生组织工程

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光物理化学实验虚拟仿真平台设计与实现

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实验室科学 2023年第1期26卷 54-57,62页

作者：黄中山王祎薛昕惟贾棋叶昕辰李梦遥王胜法大连理工大学软件学院辽宁大连116600 大连理工大学国际信息与软件学院辽宁大连116600

设计与实现了一个基于Unity3D的光物理化学过程实验虚拟仿真演示平台。该平台采用模块化设计思想,主要完成了荧光共振能量转移和荧光寿命模拟实验。不但基本实现了这两种实验的客观性和准确性,而且用户还可以更改参数,获得不同的实验结... 详细信息

设计与实现了一个基于Unity3D的光物理化学过程实验虚拟仿真演示平台。该平台采用模块化设计思想,主要完成了荧光共振能量转移和荧光寿命模拟实验。不但基本实现了这两种实验的客观性和准确性,而且用户还可以更改参数,获得不同的实验结果。该虚拟仿真实验平台有助于提高学生对理论知识的理解和学习效率,同时也可为网络远程教育等在线学习提供了新的体验途径。

关键词：光物理化学过程实验平台虚拟仿真荧光共振能量转移

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