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Flavonoids from mulberry leaves inhibit fat production and improve fatty acid distribution in adipose tissue in finishing pigs

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Animal Nutrition 2024年第1期16卷 147-157页

作者： Yingying liu Yinglin Peng Chen Chen Huibo Ren Ji Zhu Yuan Deng Qingming Cui Xionggui Hu Jianhua He huali li Xinghui Zhu Yulong Yin Jun He Yi Xiao College of Animal Science and Technology Hunan Agricultural University Hunan Institute of Animal and Veterinary Science Key Laboratory of Conservation and Genetic Analysis of Local Pig Breed Germplasm Resources College of Information and Intelligence Hunan Agricultural University Institute of Subtropical Agriculture Chinese Academy of Sciences

This study evaluated the effects of flavonoids from mulberry leaves (FML) on plasma biochemical indices,serum activities of lipid metabolism-related enzymes,fat morphology,fatty acid composition,and lipid metabolism in different adipose tissues of finishing *** used 120 Chinese hybrid barrows of Berkshire and Bama mini-pigs with an average initial body weight of 45.11±4.23 *** pigs were randomly assigned to five treatment groups and fed a control diet based on corn,soybean meal,and wheat bran or a control diet supplemented with 0.02%,0.04%,0.08%,or 0.16%*** experimental group had six replicates (pens),with four pigs per *** a 7-d adaptation period,the feeding trial was conducted for 58 *** and adipose tissue samples were collected from 30 pigs (one pig per pen)at the end of the *** results showed that FML supplementation significantly decreased the feed intake to body gain ratio,the plasma concentrations of total cholesterol and free fatty acids,and the serum activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (linear or quadratic effects,Plipoprotein lipase (linear and quadratic effects,Plipase (linear,Plinear,P=0.05) and increased the adipocyte area in the visceral adipose tissue (quadratic,Plipid metabolism genes were regulated by the PPARγ-LXRa-ABCA1 signaling pathway,and their expressions differed in different adipose *** findings suggest that FML improved growth performance,reg

关键词： Finishing pig Mulberry leaf Flavonoid lipid metabolism Fatty acid Lard

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益气活血养心汤对急性ST段抬高型心肌梗死早期溶栓患者炎症因子、心功能及预后的影响

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新中医 2024年第1期56卷 29-34页

作者：李华丽临海市中医院浙江临海317000

目的:观察益气活血养心汤对急性ST段抬高型心肌梗死(ASTEMI)早期溶栓患者炎症因子、心功能及预后的影响。方法:回顾性选取68例ASTEMI患者为研究对象,根据治疗方式不同分为对照组及观察组各34例。对照组应用早期溶栓,观察组在早期溶栓基... 详细信息

目的:观察益气活血养心汤对急性ST段抬高型心肌梗死(ASTEMI)早期溶栓患者炎症因子、心功能及预后的影响。方法:回顾性选取68例ASTEMI患者为研究对象,根据治疗方式不同分为对照组及观察组各34例。对照组应用早期溶栓,观察组在早期溶栓基础上应用益气活血养心汤治疗。比较2组临床疗效、冠状动脉恢复情况及不良反应发生率,比较2组治疗前后炎症因子[前列腺素E2(PGE2)、白细胞介素-6(IL-6)、超敏C-反应蛋白(hs-CRP)]、心功能[左室射血分数(LVEF)、左心室舒张末容积(LVEDV)、左心室收缩末容积(LVESV)]、中医症状评分的变化。结果:观察组总有效率为94.12%,对照组为76.47%,2组比较,差异有统计学意义(P0.05)。观察组不良反应发生率为8.82%,对照组为23.53%,2组比较,差异有统计学意义(P<0.05)。结论:益气活血养心汤治疗ASTEMI早期溶栓患者,能提高临床疗效,降低炎症反应,提高心功能,缓解临床症状,用药安全性高,预后较好。

关键词：急性ST段抬高型心肌梗死益气活血养心汤早期溶栓心功能预后

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摩罗丹联合四联疗法治疗幽门螺杆菌阳性慢性萎缩性胃炎临床研究

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新中医 2024年第3期56卷 33-38页

作者：李华丽临海市中医院浙江临海317000

目的:观察摩罗丹联合四联疗法治疗胃络瘀阻型幽门螺杆菌(Hp)阳性慢性萎缩性胃炎(CAG)的临床疗效。方法:选取160例胃络瘀阻型Hp阳性CAG患者为研究对象,按随机数字表法分为研究组及对照组各80例。对照组予以四联疗法治疗,研究组在此基础... 详细信息

目的:观察摩罗丹联合四联疗法治疗胃络瘀阻型幽门螺杆菌(Hp)阳性慢性萎缩性胃炎(CAG)的临床疗效。方法:选取160例胃络瘀阻型Hp阳性CAG患者为研究对象,按随机数字表法分为研究组及对照组各80例。对照组予以四联疗法治疗,研究组在此基础上予以摩罗丹口服治疗。观察2组临床疗效,比较2组治疗后Hp转阴率及不良反应发生率,比较2组治疗前后血清炎症因子[肿瘤坏死因子-α (TNF-α)、白细胞介素-1β (IL-1β)、白细胞介素-6 (IL-6)、白细胞介素-8 (IL-8)]、胃肠激素[胃泌素(GAS)、胃动素(MTL)、生长抑素(SS)]、胃蛋白酶原[胃蛋白酶原Ⅰ(PGⅠ)、胃蛋白酶原Ⅱ(PGⅡ)]含量的变化。结果:治疗后,研究组临床疗效总有效率为96.25%,对照组为78.75%,2组比较,差异有统计学意义(P0.05);研究组血清PGⅠ含量高于对照组(P0.05)。治疗期间,研究组不良反应发生率为11.25%,对照组不良反应发生率为8.75%,2组药物不良反应发生率比较,差异无统计学意义(P>0.05)。结论:摩罗丹联合四联疗法可有效提高胃络瘀阻型Hp阳性CAG临床疗效水平,增强Hp清除效果,缓解炎症反应,改善胃肠激素和胃蛋白酶原分泌水平,且不增加药物安全性风险。

关键词：慢性萎缩性胃炎幽门螺杆菌胃络瘀阻证摩罗丹四联疗法

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绒山羊腐蹄病的发病原因及其防治技术

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广东饲料 2024年第7期 48-50页

作者：李华丽岫岩满族自治县农业农村发展中心

本文重点探讨绒山羊腐蹄病的发病原因及其防治技术,综合分析了腐蹄病的病原学、流行病学、临床症状、病理变化等,总结了相应的诊断技术,并根据绒山羔羊的养殖特点提出了加强卫生管理、加强饲养管理、加强防疫管理等防治技术,以期为绒山... 详细信息

本文重点探讨绒山羊腐蹄病的发病原因及其防治技术,综合分析了腐蹄病的病原学、流行病学、临床症状、病理变化等,总结了相应的诊断技术,并根据绒山羔羊的养殖特点提出了加强卫生管理、加强饲养管理、加强防疫管理等防治技术,以期为绒山羊腐蹄病的综合研究提供有效参考。

关键词：绒山羊腐蹄病发病原因防治技术

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槐杞黄颗粒联合艾曲泊帕乙醇胺治疗儿童难治性免疫性血小板减少症的临床研究

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现代药物与临床 2024年第1期39卷 132-135页

作者：梁玉丽王丽温丽马夫天李华利全美洁李文梓赵艳荣安娜河北省儿童医院血液肿瘤科河北石家庄050000 河北省儿童医院药剂科河北石家庄050000

目的探讨槐杞黄颗粒联合艾曲泊帕乙醇胺片治疗儿童难治性免疫性血小板减少症的临床效果。方法选取2020年1月—2022年7月河北省儿童医院收治的60例儿童难治性免疫性血小板减少症患儿,将60例患儿用随机数字表法分为对照组(30例)和治疗组... 详细信息

目的探讨槐杞黄颗粒联合艾曲泊帕乙醇胺片治疗儿童难治性免疫性血小板减少症的临床效果。方法选取2020年1月—2022年7月河北省儿童医院收治的60例儿童难治性免疫性血小板减少症患儿,将60例患儿用随机数字表法分为对照组(30例)和治疗组(30例)。对照组口服艾曲泊帕乙醇胺片,初始剂量25 mg/d,随后根据血小板计数(PLT)调整剂量。治疗组在对照组基础上开水冲服槐杞黄颗粒,1袋/次,2次/d。两组均治疗6个月。比较两组的临床疗效、PLT和免疫功能。结果治疗后,治疗组总有效率显著高于对照组(P<0.05)。治疗后,两组PLT较治疗前均显著升高(P<0.05),且治疗组的PLT高于对照组(P<0.05)。治疗后,两组CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平均明显升高,CD8^(+)明显降低(P<0.05);治疗后,治疗组CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平均高于对照组,CD8^(+)低于对照组(P<0.05)。结论槐杞黄颗粒联合艾曲泊帕乙醇胺片治疗儿童难治性免疫性血小板减少症具有较好临床疗效,能够在短期内快速提升患儿PLT水平,增强免疫功能。

关键词：槐杞黄颗粒艾曲泊帕乙醇胺片儿童难治性免疫性血小板减少症血小板计数 CD3+

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Copper ions-me diate d dynamic re dox-responsive microgels synergize with silicone for efficient and sustainable antibacterial properties

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Journal of Materials Science & Technology 2023年第12期143卷 253-267页

作者： huali li liuqin Zhang Xiaohu Zhang Shuwen Luo Baoshan Yang Min Wu Wei-Hua li Fa-Qian liu School of Chemical Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Materials Science and Engineering Sun Yat-sen UniversityGuangzhou 510275China Offshore Oil Production Plant of Sinopec Shengli Oilfield Company Dongying 257237China

The antifouling of marine facilities placed below the waterline is a key constraint to the development of the marine ***,commercial Cu_(2)O-based antifouling coatings still have defects such as agglomeration,oxidation,short duration and high *** this reason,we developed for the first time a triple antifouling system consisting of Cu_(2)O@poly(NIPAM-co-DAm)(Cu_(2)O@PND)dynamic redox micro-gels triggered by copper ions and polydimethylsiloxane(PDMS).The catechol groups of PND nanogels can chelate Cu^(2+)and reduce it in situ to obtain Cu_(2)O@PND microgels,which guarantees the stable release of Cu^(+).Furthermore,Cu_(2)O remains stable and free from oxidation because of the electron transfer between PND and Cu^(2+).Finally,superior antifouling performance was achieved by combining the stable Cu^(+)re-leased from Cu_(2)O,in situ conversion of PND to hydrogel,and its oxidation to produce active substances and H_(2)O_(2),and PDMS coating with low surface energy.

关键词： Hydrogel Copper ions Dynamic redox Silicone Efficient-sustainable release Antibacterial

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Factors affecting college students’attitudes towards carpooling

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Transportation Safety and Environment 2024年第2期6卷 55-62页

作者： linchao li huali Zhang Zuoxian Gan College of Civil and Transportation Engineering Shenzhen UniversityShenzhen 518060China College of Transportation Engineering Dalian Maritime UniversityDalian 116026LiaoningChina

As a sustainable mode of travel,carpooling is an effective solution to environmental and energy problems,but it has not been fully *** research on carpooling attitudes,especially for college students,still needs to be *** response to this problem,this paper aims to investigate the effect of personal attributes,travel attributes,attitude attributes and other attributes of students on carpooling attitudes in *** collect the data,an online questionnaire survey was implemented at Shenzhen University,and 514 students *** on the samples,the multinomial logit model is used to explore the contribution of all *** model results showed that personal attributes such as sex and age had no significant effect on the attitude of college students towards *** safety of carpooling and its high cost make college students have a neutral attitude towards *** most concerning factor for college students in carpooling is *** findings can provide valuable suggestions for measures to be taken in response to different attributes affecting students’attitudes and are particularly important for the university and government to make optimal decisions to motivate students to select carpooling.

关键词： carpooling attitudes college students multinomial logit traffic environment

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Melatonin delays leaf senescence in pak choi(Brassica rapa ***)by regulating biosynthesis of the second messenger cGMP

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Horticultural Plant Journal 2024年第1期10卷 145-155页

作者： Xuesong liu Ronghui An Guofeng li Shufen Luo huali Hu Pengxia li Institute of Agricultural Facilities and Equipment Jiangsu Academy of Agricultural SciencesNanjingJiangsu 210014China School of Food and Biological Engineering Jiangsu UniversityZhenjiangJiangsu 212013China Jiangsu Key Laboratory for Horticultural Crop Genetic Improvement NanjingJiangsu 210014China Key Laboratory of Cold Chain Logistics Technology for Agro-Products Ministry of Agriculture and Rural AffairsNanjingJiangsu 210014China Jinan Fruit Research Institute All China Federation of Supply and Marketing CooperativesJinanShandong 250220China

Melatonin(MT)is a low molecular weight compound with multiple biological functions in *** is known to delay leaf senescence in various ***,no data are available on the MT signaling pathway in postharvest *** study demonstrates that MT increases cGMP concentration and the expression of the cGMP synthesis gene BcGC1 in pak *** c GMP inhibitor LY83583 destroys effect of MT delaying the leaf ***83583 also prevents MT treatment from reducing the expression of chlorophyll metabolism-related genes(BcNYC1,BcNOL,BcPPH1/2,BcSGR1/2,and BcPAO)and senescence genes(BcSAG12 and BcSAG21).It also inhibits MT from reducing the activity of the key chlorophyll catabolism enzymes Mg-dechelatase,pheophytinase,and pheide a ***,the ability of MT to maintain high levels of chlorophyll metabolites is also *** Arabidopsis c GMP synthetic gene mutant atgc1 was used to confirm that delayed leaf senescence caused by MT is mediated,at least in part,by the second messenger c GMP.

关键词： Pak choi Melatonin cGMP Chlorophyll degradation Senescence

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岫岩县辽宁绒山羊产业发展调查报告与建议

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现代畜牧兽医 2024年第1期 54-59页

作者：孙亚波刘颖徐晓江韩迪贾富勃吴世海于明李华丽辽宁农业职业技术学院畜牧兽医学院辽宁营口115009 岫岩县农业农村中心辽宁鞍山118400 辽宁省现代农业生产基地建设工程中心辽宁沈阳110032

调查旨在全面掌握岫岩县绒山羊产业发展的现状和存在的问题,采用现场调查、问卷调查和电话调查等多种方法,于2022年7月—2023年4月对岫岩县24个乡镇的221个养殖场(户)开展了产业情况、产业技术水平、饲草料情况和加工流通等方面的调研... 详细信息

调查旨在全面掌握岫岩县绒山羊产业发展的现状和存在的问题,采用现场调查、问卷调查和电话调查等多种方法,于2022年7月—2023年4月对岫岩县24个乡镇的221个养殖场(户)开展了产业情况、产业技术水平、饲草料情况和加工流通等方面的调研。结果显示:岫岩县绒山羊饲养量、羊肉产量自2019年以来一直呈上升趋势;养殖规模以中小型养殖场(户)为主;大中规模的养殖场主要以育肥为主,随着规模降低逐渐过渡为自繁自养方式。2021—2023年,母羊繁殖效率和羔羊培育效率不断增强,育肥效益较好,绝大多数养殖场能够定期免疫。养殖方式以舍饲和半舍饲为主,日粮配方化水平不高。产品加工环节较薄弱,缺少专门的加工企业。研究表明,岫岩县绒山羊产业发展趋势较好,生产技术水平逐年提高,但也存在生物安全重视程度不够、疫病防控成本较高等技术问题和产品加工流通薄弱等产业问题。因此,建议进一步提高绒山羊良种化水平,加强生物安全防控工作,加大开发新的饲料资源力度,行业主管部门加强对产品加工流通的政策引导和扶持,为岫岩县绒山羊产业持续健康发展助力。

关键词：岫岩县辽宁绒山羊养羊业

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Parameter optimization and experiment of the negative pressure precision seed-metering device for wheat

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International Journal of Agricultural and Biological Engineering 2024年第1期17卷 154-162页

作者： Yubo Feng Xiaoshun Zhao Jincai li huali Yu Hongpeng Zhao Baozhong Yin State Key Laboratory of North China Crop Improvement and Regulation Hebei Agricultural UniversityBaoding 071001HebeiChina College of Mechanical and Electrical Engineering Hebei Agricultural UniversityBaoding 071001HebeiChina College of Plant Protection Hebei Agricultural UniversityBaoding 071001HebeiChina

In order to ensure the most reasonable distribution of wheat seeds in the field to improve seeding quality and uniformity,a set of negative pressure precision seed-metering device was designed,which shares a hollow *** seed-metering device can sow two rows of *** the STAR-CCM+,the analysis of nephogram,vectogram and streamline graph showed that more ideal structural parameters of the seed-metering device are 0.5 mm width of the slit sucking seed(WSS),150-200 mm diameter of the seed-metering disc(DSD),2.0 mm axial depth of air chamber in the seed-metering disc(ADS),and arc-shaped cross-section shape of the ring groove sucking seed(CSGS).Single-factor test on the JPS-12 test-bed analyzed the influence of the CSGS,WSS,DSD,and ADS on the qualified index(Iq),multiple index(Imul),miss index(Imiss)and coefficient of variation of qualified seed spacing(CV).Through the orthogonal on the JPS-12 test-bed,it is found that the influence of vacuum negative pressure and seed-metering device shaft speed is significant on the Iq,Imiss and *** on these,the structural parameters of the seed-metering device were *** DSD is 180 mm,the WSS is 0.7 mm,the ADS is 2.5 mm,and the CSGS is *** optimization seed-metering device was tested on the JPS-12 *** Iq is 86.66%,the Imiss is 5.09%,the Imul is 8.25%,and the CV is 24.50%.These testing results fully coincide with the standard JB/T 10293-2013 Specifications of single seed drill(precision drill).The seed-metering device meets fully the requirements for wheat precision seeding.

关键词： wheat seed-metering device negative pressure precision parameter optimization STAR-CCM+ orthogonal test variance analysis

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