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Identification of candidate genes for early-maturity traits by combining BSA-seq and QTL mapping in upland cotton(Gossypium hirsutum L.)

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Journal of Integrative Agriculture 2024年第10期23卷 3472-3486页

作者： Liang Ma Tingli Hu meng Kang Xiaokang fu Pengyun Chen Fei Wei Hongliang Jian Xiaoyan Lü meng Zhang Yonglin Yang State Key Laboratory of Cotton Bio-breeding and Integrated Utilization/Institute of Cotton Research Chinese Academy ofAgricultural SciencesAnyang 455000China School of Agriculture Henan Institute of Science and TechnologyXinxiang 453003China Shihezi Academy of Agricultural Sciences Shihezi 832099China

Cotton breeding for the development of early-maturing varieties is an effective way to improve multiple cropping indexes and alleviate the conflict between grains and cotton in the cultivated fields in *** the present study,we aimed to identify upland cotton quantitative trait loci(QTLs)and candidate genes related to early-maturity traits,including whole growth period(WGP),flowering timing(FT),node of the first fruiting branch(NFFB),height of the node of the first fruiting branch(HNFFB),and plant height(PH).An early-maturing variety,CCRI50,and a latematuring variety,Guoxinmian 11,were crossed to obtain biparental *** populations were used to map QTLs for the early-maturity traits for two years(2020 and 2021).With BSA-seq analysis based on the data of population 2020,the candidate regions related to early maturity were found to be located on chromosome *** then developed 22 polymorphic insertions or deletions(InDel)markers to further narrow down the candidate regions,resulting in the detection of five and four QTLs in the 2020 and 2021 populations,*** to the results of QTL mapping,two candidate regions(InDel_G286-InDel_G144 and InDel_G24-InDel_G43)were *** these regions,three genes(GH_D03G0451,GH_D03G0649,and GH_D03G1180)have nonsynonymous mutations in their exons and one gene(GH_D03G0450)has SNP variations in the upstream sequence between CCRI50 and Guoxinmian *** four genes also showed dominant expression in the floral *** expression levels of GH_D03G0451,GH_D03G0649 and GH_D03G1180 were significantly higher in CCRI50 than in Guoxinmian 11 during the bud differentiation stages,while GH_D03G0450 showed the opposite *** functional verification of GH_D03G0451 indicated that the GH_D03G0451-silenced plants showed a delay in the flowering *** results suggest that these are the candidate genes for cotton early maturity,and they may be used for breeding early-maturity cotton varieties.

关键词： cotton genomics early-maturity traits BSA-seq QTL mapping molecular breeding

Ingredients-based Methodology and fuzzy Logic Combined Short-Duration Heavy Rainfall Short-Range Forecasting:An Improved Scheme

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Journal of Tropical Meteorology 2024年第3期30卷 241-256页

作者： TIAN fu-you XIA Kun SUN Jian-hua ZHENG Yong-guang hua Shan National Meteorological Center Beijing100081 China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of Sciences(IAP/CAS)Beijing 100029 China Key Laboratory of Cloud-Precipitation Physics and Severe Storms(LACS) Institute of Atmospheric PhysicsChinese Academy of Sciences(IAP/CAS)Beijing 100029 China

Short-duration heavy rainfall(SHR),as delineated by the National Meteorological Center of the China Me-teorological Administration,is characterized by hourly rainfall amounts no less than 20.0 *** is one of the most common convective weather phenomena that can cause severe ***-range forecasting of SHR is an important part of operational severe weather *** the present study,an improved objective SHR forecasting scheme was developed by adopting the ingredients-based methodology and using the fuzzy logic *** 1.0°×1.0°National Centers for Environmental Prediction(NCEP)final analysis data and the ordinary rainfall(0.1-19.9 mm h-1)and SHR observational data from 411 stations were used in the improved *** best lifted index,the total precipitable water,the 925 hPa specific humidity(Q 925),and the 925 hPa divergence(DIV 925)were selected as predictors based on objective *** distributed membership functions of predictors were obtained based on relative frequency *** weights of predictors were also objectively *** with a typhoon SHR case and a spring SHR case show that the main possible areas could be captured by the improved *** of SHR forecasts within 96 hours with NCEP global forecasts 1.0°×1.0°data initiated at 08:00 Beijing Time during the warm seasons in 2015 show the results were improved from both deterministic and probabilistic *** study provides an objectively feasible choice for short-range guidance forecasts of *** scheme can be applied to other convective phenomena.

关键词： ingredients-based methodology fuzzy logic approach probability of short-duration heavy rainfall(SHR) improved forecasting scheme objectively obtained membership functions

Efficient removal of Cr(VI) by polydopamine-modified lignin from aqueous solution: Batch and XAFS studies

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Water Science and Engineering 2024年第1期17卷 51-61页

作者： Xiao-jie Guo Wei-kang fu Jing-yuan Ma Bo-jun Xi Chen Wang meng-yao Guan College of Materials and Environmental Engineering Hangzhou Dianzi UniversityHangzhou 310018China College of Textile and Garment Shaoxing UniversityShaoxing 312000China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China

Lignocellulose has the potential to become a bio-based adsorbent due to its biodegradability and *** this study,a novel polydopamine functionalized-lignin(lignin@PDA),prepared via self-polymerization of dopamine(PDA)on lignin,was used as a bio-based adsorbent for rapid scavenging of hexavalent chromium(Cr(VI)).The morphology,functional groups,crystalline structure,and chemical composition of lignin@PDA were characterized with a scanning electron microscope-energy dispersive spectrometer,Fourier transform infrared spectroscopy,X-ray diffraction,and X-ray photoelectron *** Cr(VI)adsorption process of lignin@PDA was studied using batch experiments as a function of pH,ionic strength,adsorbent dose,and contact time at room *** adsorption rate of lignin@PDA was five times greater than that of the unmodified lignin,with a maximum adsorption capacity of 102.6 mg/g in an acidic *** adsorption of Cr(VI)on lignin@PDA fit the pseudo-secondorder equation and the Freundlich model,indicating that the adsorption process was mainly dominated by chemisorption and surface *** thermodynamic parameters showed that adsorption of Cr(VI)on lignin@PDA was an endothermic and spontaneous *** X-ray absorption fine structure results showed that sorption and reduction of Cr(VI)into Cr(II)occurred simultaneously on ***,PDA coating not only improved the reactivity of lignin but also promoted the complete reduction of Cr(VI)by *** to these results,polydopamine functionalized-lignin is a promising bio-based adsorbent for immobilization of Cr(VI)from wastewater.

关键词： Lignin Polydopamine Hexavalent chromium EXAFS Adsorption mechanism

Safety,immunogenicity and protective effect of sequential vaccination with inactivated and recombinant protein COVID-19 vaccine in the elderly:a prospective longitudinal study

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2738-2747页

作者： Hong-Hong Liu Yunbo Xie Bao-Peng Yang huan-Yue Wen Peng-Hui Yang Jin-E Lu Yan Liu Xi Chen meng-meng Qu Yang Zhang Wei-Guo Hong Yong-Gang Li Junliang fu fu-Sheng Wang Out-patient Department of Day Diagnosis and Treatment The Fifth Medical Center of Chinese PLA General HospitalBeijing 100039China Senior Department of Infectious Diseases The Fifth Medical Center of Chinese PLA General HospitalNational Clinical Research Center for Infectious DiseasesBeijing 100039China Chinese PLA Medical School Chinese PLA General HospitalBeijing 100039China Hunyuan County People’s Hospital Datong 037499 Shanxi ProvinceChina Faculty of Hepato-Pancreato-Biliary Surgery Institute of Hepatobiliary SurgeryThe First Medical CenterChinese PLA General HospitalBeijing 100853China

The safety and efficacy of COVID-19 vaccines in the elderly,a high-risk group for severe COVID-19 infection,have not been fully *** clarify these issues,this prospective study followed up 157 elderly and 73 young participants for 16 months and compared the safety,immunogenicity,and efficacy of two doses of the inactivated vaccine BBIBP-CorV followed by a booster dose of the recombinant protein vaccine *** results showed that this vaccination protocol was safe and tolerable in the *** administering two doses of the BBIBP-CorV,the positivity rates and titers of neutralizing and anti-RBD antibodies in the elderly were significantly lower than those in the young *** the ZF2001 booster dose,the antibody-positive rates in the elderly were comparable to those in the young;however,the antibody titers remained ***,age,and underlying diseases were independently associated with vaccine immunogenicity in elderly *** pseudovirus neutralization assay showed that,compared with those after receiving two doses of BBIBP-CorV priming,some participants obtained immunological protection against BA.5 and BF.7 after receiving the ZF2001 *** infection symptoms last longer in the infected elderly and pre-infection antibody titers were negatively associated with the severity of post-infection *** antibody levels in the elderly increased significantly after breakthrough infection but were still lower than those in the *** data suggest that multiple booster vaccinations at short intervals to maintain high antibody levels may be an effective strategy for protecting the elderly against COVID-19.

关键词： vaccination vaccine doses

NLRP3-mediated autophagy dysfunction links gut microbiota dysbiosis to tau pathology in chronic sleep deprivation

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Zoological Research 2024年第4期45卷 857-874页

作者： Na Zhao Xiu Chen Qiu-Gu Chen Xue-Ting Liu Fan Geng meng-meng Zhu fu-Ling Yan Zhi-Jun Zhang Qing-Guo Ren Department of Neurology School of MedicineSoutheast UniversityNanjingJiangsu 210009China Department of Neurology Affiliated Zhongda HospitalSoutheast UniversityNanjingJiangsu 210009China

Emerging evidence indicates that sleep deprivation(SD)can lead to Alzheimer’s disease(AD)-related pathological changes and cognitive ***,the underlying mechanisms remain *** the present study,we identified the existence of a microbiota-gut-brain axis in cognitive deficits resulting from chronic SD and revealed a potential pathway by which gut microbiota affects cognitive functioning in chronic *** findings demonstrated that chronic SD in mice not only led to cognitive decline but also induced gut microbiota dysbiosis,elevated NLRP3 inflammasome expression,GSK-3βactivation,autophagy dysfunction,and tau hyperphosphorylation in the *** with the“SD microbiota”replicated the pathological and behavioral abnormalities observed in chronic sleep-deprived ***,both the deletion of NLRP3 in NLRP3-/-mice and specific knockdown of NLRP3 in the hippocampus restored autophagic flux,suppressed tau hyperphosphorylation,and ameliorated cognitive deficits induced by chronic SD,while GSK-3βactivity was not regulated by the NLRP3 inflammasome in chronic ***,deletion of NLRP3 reversed NLRP3 inflammasome activation,autophagy deficits,and tau hyperphosphorylation induced by GSK-3βactivation in primary hippocampal neurons,suggesting that GSK-3β,as a regulator of NLRP3-mediated autophagy dysfunction,plays a significant role in promoting tau ***,gut microbiota dysbiosis was identified as a contributor to chronic SD-induced tau pathology via NLRP3-mediated autophagy dysfunction,ultimately leading to cognitive ***,these findings highlight GSK-3βas a regulator of NLRP3-mediated autophagy dysfunction,playing a critical role in promoting tau hyperphosphorylation.

关键词： Chronic sleep deprivation Tau pathology NLRP3 inflammasome Autophagy GSK-3β Microbiota-gut-brain axis

Enhancing the electrocatalytic performance of nitrate reduction to ammonia by in-situ nitrogen leaching

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Chinese Chemical Letters 2024年第2期35卷 564-569页

作者： Mimi fu Yini Mao hua Wang Wei Luo Yimin Jiang Wei Shen Ming Li Rongxing He College of Chemistry and Chemical Engineering Southwest UniversityChongqing 400715China

Electrochemical nitrate reduction reaction (NITRR) is regarded as a “two birds-one stone” method for the treatment of nitrate contaminant in polluted water and the synthesis of valuable ammonia, which is retarded by the lack of highly reactive and selective electrocatalysts .Herein, for the first time, nickel foam supported Co_(4) N was designed as a high-performance NITRR catalyst by an in-situ nonmetal leaching-induced *** the optimal potential, the Co_(4) N/NF catalyst achieves ultra-high Faraday efficiency and NH_(3) selectivity of 95.4% and 99.4%, *** situ X-ray absorption spectroscopy (XAS), together with other experiments powerfully reveal that the nitrogen vacancies produced by nitrogen leaching are stable and play a key role in boosting nitrate reduction to *** calculations confirm that Co_(4) N with abundant nitrogen vacancies can optimize the adsorption energies of NO_(3)^(-) and intermediates, lower the free energy (Δ G ) of the potential-determining step (*NH_(3) to NH_(3) ) and inhibit the formation of N-containing *** addition, we also conclude that the nitrogen vacancies can stabilize the adsorbed hydrogen, making H_(2) quite difficult to produce, and lowering ΔG from *NO to *NOH, which facilitates the selective reduction of *** study reveals significant insights about the in-situ nonmetal leaching to enhance the NITRR activity.

关键词： Co4N Nitrate reduction In-situ nonmetal leaching Nitrogen vacancy Mechanism

Oxidation resistant low-alloyed Ti alloys with good ductility

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Rare Metals 2024年第8期43卷 3921-3936页

作者： meng Li Zhang-Zhi Shi Jun-Yi Xu fu-Zhi Dai Xiang-Min Li Zi-Lin Li Lu-Ning Wang Beijing Advanced Innovation Center for Materials Genome Engineering State Key Laboratory for Advance Metals and MaterialsSchool of Materials Science and EngineeringUniversity of Science and Technology BeijingBeijingBeijing 100083China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China

Oxidation resistance enhancement of pure Ti often comes at the cost of reduced ductility,which is frequently the problem through alloying with sole Al,Si,W,Mo and *** overcome the short coming of single element alloying,this paper proposes a multi-element low-alloying strategy to take advantage of synergistic effects and resolve the conflict between oxidation resistance and *** demonstrates that the addition of a small quantity of Ta(0.51wt%)can boost both oxidation resistance and ductility in comparison to pure ***,the combined addition of a small amount(0.54 wt%)of Ta,Nb and Si not only preserves good ductility of pure Ti,but also reduces mass gains to 14%-67%of pure Ti during 100 h oxidation at 650-850℃in *** indicates even better oxidation resistance than that obtained through the use of Ta,Nb,or Nb+Ta *** Ta+Nb+Si alloying creates an oxide layer that is less porous and more resistant to stratification and ***,a 3-μm N-rich layer can form in the Ti substrate beneath the oxide scale,in which phase transformation generates coherent Ti_(2)N with(0001)_(Ti)as the habit plane,with N atoms prefers to diffuse along■than along[0001]_(Ti).The completely transformed Ti_(2)N region or partially transformed Ti+Ti_(2)N region can effectively impede oxygen ***,the multielement low-alloying strategy is promising for enhancing both oxidation resistance and mechanical properties of metallic materials in the future.

关键词： Ti alloys Multi-element Co-alloying Oxidation resistance Mechanical properties

Thermo-hydro-poro-mechanical responses of a reservoir-induced landslide tracked by high-resolution fiber optic sensing nerves

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第3期16卷 1018-1032页

作者： Xiao Ye Hong-Hu Zhu Gang Cheng hua-fu Pei Bin Shi Luca Schenato Alessandro Pasuto School of Earth Sciences and Engineering Nanjing UniversityNanjing210023China School of Computer Science North China Institute of Science and Technology(National Safety Training Center of Coal Mines)Beijing101601China State Key Lab of Coastal and Offshore Engineering Department of Geotechnical EngineeringDalian University of TechnologyDalian116024China National Research Council-Research Institute for Geo-Hydrological Protection(CNR-IRPI) Padova35127Italy Department of Information Engineering University of PadovaPadova35131Italy

Thermo-poro-mechanical responses along sliding zone/surface have been extensively ***,it has not been recognized that the potential contribution of other crucial engineering geological interfaces beyond the slip surface to progressive ***,we aim to investigate the subsurface multiphysics of reservoir landslides under two extreme hydrologic conditions(*** and dry),particularly within sliding *** on ultra-weak fiber Bragg grating(UWFBG)technology,we employ specialpurpose fiber optic sensing cables that can be implanted into boreholes as“nerves of the Earth”to collect data on soil temperature,water content,pore water pressure,and *** Xinpu landslide in the middle reach of the Three Gorges Reservoir Area in China was selected as a case study to establish a paradigm for in situ thermo-hydro-poro-mechanical *** UWFBG-based sensing cables were vertically buried in a 31 m-deep borehole at the foot of the landslide,with a resolution of 1 m except for the pressure *** reported field measurements covering the period 2021 and 2022 and produced the spatiotemporal profiles throughout the *** show that wet years are more likely to motivate landslide motions than dry *** annual thermally active layer of the landslide has a critical depth of roughly 9 m and might move downward in warmer *** dynamic groundwater table is located at depths of 9e15 m,where the peaked strain undergoes a periodical response of leap and withdrawal to annual hydrometeorological *** interface behaviors may support the interpretation of the contribution of reservoir regulation to slope stability,allowing us to correlate them to local damage events and potential global *** paper also offers a natural framework for interpreting thermo-hydro-poro-mechanical signatures from creeping reservoir bank slopes,which may form the basis for a landslide monitoring and early warning system.

关键词： Reservoir landslide Thermo-hydro-poro-mechanical response Ultra-weak fiber bragg grating(UWFBG) subsurface evolution Engineering geological interface Geotechnical monitoring

A novel long persistent luminescent material CaGeO_(3):Tb^(3+)with photo-stimulation properties

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Journal of Rare Earths 2024年第7期42卷 1233-1239,I0002页

作者： Wei meng Xiaoyan fu Tongyan Lin Zewen Liu Naihui Chen Jiaxu Zhang Runyao Liu Rujun Yang Long Chen Hongwu Zhang School of Chemistry and Material Sciences Ludong UniversityYantai264025China College of Materials Science and Engineering Xiamen University of TechnologyXiamen361024China College of Materials Xiamen UniversityXiamen361005China

A novel green long afterglow material CaGeO_(3):Tb^(3+)was synthesized by high temperature solid phase *** to the experimental results,CaGeO_(3):Tb^(3+)is a green long persistent luminescent(LPL)material with excellent ***_(3):Tb^(3+)shows LPL emission peak at 442,490.9,548.7,588.5 and 623.8 nm,corresponding to ^(5)D_(3) to^(7)F_(4)and^(5)D_(4)to^(7)F_(J)(J=6,5,4,3)transitions of Tb^(3+).Its CIE coordinates are(0.27,0.50),indicating that the afterglow emission is close to the light of green *** addition,after the excitation source is turned off,the afterglow time is longer than 90 *** an interval of 7 h,the photo-stimulation luminescence(PSL)can be observed by using 980 nm laser cyclic *** thermoluminescence(ThL)results show that there are three types of traps in the material and their depths are 0.666,0.774 and 0.892 eV respectively,which are caused by the doping of Tb^(3+).All the results show that CaGeO_(3):Tb^(3+)is an excellent long afterglow luminescent material.

关键词： Long persistent luminescence Photo-stimulation Trap CaGeO_(3):Tb^(3+) Rare earths