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Genes & Diseases 2024年第3期11卷 34-38页

作者： mj Mahesh Kumar Shailendra Arindkar Masum Saini Perumal Nagarajan National Institute of Immunology New Delhi 100067India Center for Cellular and Molecular Biology Hyderabad 500007India Regional Center for Biotechnology Faridabad 121001India

Non-alcoholic fatty liver disease(NAFLD)and type 2 diabetes mellitus(T2DM)are two disease conditions for which obesity is a risk factor.^(1)Due to the close relationship between the three pathologies,researchers frequently use the same mouse models to identify the underlying processes of obesity,NAFLD,and *** instance,leptin(Lep)-null(ob/ob)and leptin receptor(Lepr)-deficient(db/db)mice spontaneously develop NAFLD and show different phenotypes of extreme obesity and diabetes,respectively.

关键词： obesity NAFLD Lep

Development of an experimental method for well-controlled blast induced traumatic limb fracture in rats

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Defence Technology（防务技术） 2024年第4期34卷 168-176页

作者： Luyang Xu Xiancheng Yu Clement DFavier Ibidumo Igah Thuy-Tien Nguyen Warren Macdonald Anthony mj.Bull Centre for Blast Injury Studies Imperial College LondonLondonUnited Kingdom Department of Bioengineering Imperial College LondonLondonUnited Kingdom Dyson School of Design Engineering Imperial College LondonLondonUnited Kingdom Department of Trauma and Orthopaedics Royal Free London National Health Service Foundation TrustLondonUnited Kingdom

Heterotopic ossification(HO)is a consequence of traumatic bone and tissue damage,which occurs in 65%of military casualties with blast-associated ***,the mechanisms behind blast-induced HO remain *** models are used to study blast-induced HO,but developing such models is challenging,particularly in how to use a pure blast wave(primary blast)to induce limb fracture that then requires an *** studies,including our recent study,have developed platforms to induce limb fractures in rats with blast loading or a mixture of blast and impact ***,these models are limited by the survivability of the animal and repeatability of the *** this study,we developed an improved platform,aiming to improve the animal's survivability and injury repeatability as well as focusing on primary blast *** platform exposed only one limb of the rat to a blast wave while providing proper protection to the rest of the rat's *** obtained very consistent fracture outcome in the tibia(location and pattern)in cadaveric rats with a large range of size and ***,the rats did not obviously move during the test,where movement is a potential cause of uncontrolled *** further conducted parametric studies by varying the features of the design of the *** factors,such as how the limb is fixed and how the cavity through which the limb is placed is sealed,significantly affect the resulting *** platform and test setups enable well-controlled limb fracture induced directly by pure blast wave,which is the fundamental step towards a complete in vivo animal model for blast-induced HO induced by primary blast alone,excluding secondary and tertiary blast *** addition,the platform design and the findings presented here,particularly regarding the proper protection of the animal,have implications for future studies investigating localized blast injuries,such as blast induced brain and lung injuries.

关键词： Blast injury Biomechanics Heterotopic ossification Limb fracture Blast wave Animal model

A Sustainable Strategy for Spent Cathode Carbon Blocks Hazardous Waste Recycling Using Binary Molten Salt Thermal Treatment

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Journal of Thermal Science 2024年第3期33卷 1082-1093页

作者： LI Bin DING Yan JIAO Yuyong XU Fang WANG Xinyang ZHENG Fei ZOU Junpeng GAO Qiang hu Hongyun Faculty of Engineering China University of GeosciencesWuhan430074China Institute for Natural Disaster Risk Prevention and Emergency Management China University of GeosciencesWuhan430074China State Key Laboratory of Coal Combustion Huazhong University of Science and TechnologyWuhan430074China

Waste-to-Energy treatment is a promising path to environment and energy management in the *** work detailed a binary molten salt thermal treatment methodology for the detoxification of spent cathode carbon block(SCCB)waste and the recycling of carbonaceous *** thermal behavior of SCCB and SCCB blended with molten salts was *** was found that the NaCl-Na_(2)CO_(3)binary molten salts significantly contributed to reducing pyrolysis onset temperature by 334.3 K compared to that of SCCB itself(i.e.,activation energy of pyrolysis reaction was reduced from 4.24×10^(5)to 2.30×10^(5)J/mol),thus helping to lower thermal treatment energy *** the addition of binary molten salts,the residue after thermal treatment in a horizontal tube furnace experiment was separated into two *** bottom-layer residue was mainly composed of molten *** fluorine content in the form of NaF and CaF_(2)of top-layer residue was reduced significantly while the carbon content remained ***,the leaching concentration of fluoride ion was decreased from 4620 mg/L to 856 mg/*** is noted that the NaF and CaF_(2)can be removed through water-leaching and hydrothermal acid-leaching methods and thus the carbonaceous materials with a calorific value of 17.5 mj/kg were obtained.

关键词： spent cathode carbon block hazardous solid waste detoxification binary-molten-salt thermal treatment carbon recycling pyrolysis kinetics

Atomization characteristics of pyrolysis oil derived from waste tires

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Waste Disposal and Sustainable Energy 2024年第1期6卷 39-52页

作者： Hong Feng Zhitong Yin Qin Hong Yiming hu Lintao Liu Jun Wang Qunxing huang Yonggang Zhou ZJMI Environmental Energy Co. LtdHangzhou310003China Tongxiang Taiaisi Environmental Protection Energy Co. Ltd.Jiaxing314500China State Key Laboratory of Clean Energy Utilization Zhejiang UniversityHangzhou310027China Key Laboratory of Clean Energy and Carbon Neutrality of Zhejiang Province Jiaxing Research InstituteZhejiang UniversityJiaxing314031China

The atomization characteristics play a key role in the highly efficient combustion of pyrolysis oil derived from waste *** this study,the fuel properties of tire pyrolysis oil(TPO)were initially studied,and then a high-speed camera and a phase Doppler particle analyzer were employed to characterize the atomization feature of *** influence of pressure and nozzle orifice diameter on atomization characteristics such as spray angle,droplet velocity,and droplet size distribution was *** results showed that TPO had a high calorific value of about 43.6 mj/kg and a low viscosity of 3.84×10^(–6)m^(2)/s at 40℃,which made it have the potential to be used as an alternative *** pressure expanded the spray angle and extended the spray in both the axial and radial *** increasing pressure,spray angle and droplet velocity raised,and the increase in crushing effect of air reduced the Sauter mean diameter(SMD)of the *** obtain proper atomization quality for combustion,the pressure is expected to be higher than 1.25 *** increasing nozzle orifice diameter,droplet velocity increased,and the SMD of the droplets increased as well due to weakened crushing effect of the ***,the pressure must be increased to maintain the atomization quality when using a nozzle with a larger *** to the lower viscosity,the velocity and particle size distribution of TPO droplets after atomization were smaller than those of diesel *** extremely small carbon black contained in TPO also contributed to the breaking of droplets and played a certain role in the size reduction of the oil droplets,but it may cause the risk of nozzle *** summary,TPO showed great atomization characteristics for alternative fuel applications.

关键词： Pyrolysis oil Atomization characteristics Spray angle Droplet velocity Droplet size distribution

Tough Semi-interpenetrating Polyvinylpyrrolidone/Polyacrylamide Hydrogels Enabled by Bioinspired Hydrogen-bonding Induced Phase Separation

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Chinese Journal of Polymer Science 2024年第5期42卷 591-603,I0006页

作者： Qiong-Jun Xu Zhao-Yang Yuan Chang-Cheng Wang Hao Liang Yu Shi Hai-Tao Wu hu Xu Jing Zheng Jin-Rong Wu State Key Laboratory of Polymer Materials Engineering College of Polymer Science and EngineeringSichuan UniversityChengdu610065China

Semi-interpenetrating(semi-IPN)hydrogels formed by the continuous interpenetration of cross-linked polymer network and linear non-crosslinked polymer with multifunctionality are widely used in biomedical and other ***,the negative impact of linear polymer on the homogeneity of the cross-linked network often leads to a decrease in the mechanical properties of semi-IPN hydrogels and severely limits their ***,a bioinspired hydrogen-bonding induced phase separation strategy is presented to construct the tough semi-IPN polyvinylpyrrolidone/polyacrylamide hydrogels(named PVP/PAM hydrogels),including the linear polymer polyvinylpyrrolidone(PVP)and cross-linked polyacrylamide(PAM)*** resultant PVPx/PAM hydrogels exhibit unique phase separation induced by the hydrogen bonding between PVP and PAM and affected by the amount of substance of ***,the phase separation of PVPx/PAM hydrogels results in excellent mechanical properties with a strain of 2590%,tensile strength of 0.28 MPa and toughness of 2.17 mj/m^(3).More importantly,the hydrogen bonding between PVP and PAM firstly disrupts to dissipate energy under external forces,so the PVPx/PAM hydrogels exhibit good self-recovery properties and outperform chemically cross-linked PAM hydrogels in impact resistance and damping *** is believed that the PVPx/PAM hydrogels with hydrogen-bonding induced phase separation possess more potential application prospects.

关键词： Tough Semi-interpenetrating networks Polyvinylpyrrolidone/polyacrylamide Hydrogels Phase separation

Non-enzymatic methods for isolation of stromal vascular fraction and adipose-derived stem cells:A systematic review

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World Journal of Methodology 2024年第2期14卷 134-144页

作者： Vamsi Krishna Mundluru mj Naidu Ravi Teja Mundluru Naveen Jeyaraman Sathish Muthu Swaminathan Ramasubramanian Madhan Jeyaraman Department of Orthopaedics MJ Naidu Super Speciality HospitalVijayawada 520002Andhra PradeshIndia Department of Regenerative Medicine StemC ClinicsVijayawada 520002Andhra PradeshIndia Department of Orthopaedics ACS Medical College and HospitalDr.MGR Educational and Research InstituteChennai 600077Tamil NaduIndia Department of Orthopaedics Orthopaedic Research GroupCoimbatore 641045Tamil NaduIndia Department of Orthopaedics Government Medical College and HospitalKarur 639004Tamil NaduIndia Department of Biotechnology Faculty of EngineeringKarpagam Academy of Higher EducationCoimbatore 641021Tamil NaduIndia Department of Orthopaedics Government Medical CollegeOmandurar Government EstateChennai 600002Tamil NaduIndia

BACKGROUND Adipose-derived stem cells(ADSCs)and the stromal vascular fraction(SVF)have garnered substantial interest in regenerative medicine due to their potential to treat a wide range of *** enzymatic methods for isolating these cells face challenges such as high costs,lengthy processing time,and regulatory *** This systematic review aimed to assess the efficacy and practicality of nonenzymatic,mechanical methods for isolating SVF and ADSCs,comparing these to conventional enzymatic *** Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines,a comprehensive literature search was conducted across multiple *** were selected based on inclusion criteria focused on non-enzymatic isolation methods for SVF and ADSCs from adipose *** risk of bias was assessed,and a qualitative synthesis of findings was performed due to the methodological heterogeneity of the included *** Nineteen studies met the inclusion criteria,highlighting various mechanical techniques such as centrifugation,vortexing,and ultrasonic *** review identified significant variability in cell yield and viability,and the integrity of isolated cells across different non-enzymatic methods compared to enzymatic *** some advantages of mechanical methods,including reduced processing time and avoidance of enzymatic reagents,the evidence suggests a need for optimization to match the cell quality and therapeutic efficacy achievable with enzymatic *** Non-enzymatic,mechanical methods offer a promising alternative to enzymatic isolation of SVF and ADSCs,potentially simplifying the isolation process and reducing regulatory ***,further research is necessary to standardize these techniques and ensure consistent,high-quality cell yields for clinical *** development of efficient,safe,and reproducible non-enzymatic isolation methods could signi

关键词： Adipose-derived stem cells Stromal vascular fraction Regenerative medicine Non-enzymatic isolation Mechanical separation techniques

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基于辐射型反射涂层的热控制墙体性能分析

东南大学学报（自然科学版） 2024年第2期54卷 465-474页

作者：胡轩宇殷勇高赵兴旺东南大学能源与环境学院南京211189 东南大学低碳型建筑环境设备与系统节能教育部工程研究中心南京211189

为评估基于辐射型反射涂层的热控制墙体节能效果,解决相关评测体系缺失问题,建立墙体瞬态传热模型,探究复杂气候交变环境下墙体温度和热流的动态特性,以及辐射换热在被动式制冷过程中的热调控作用,基于热流和墙体传热系数提出一种新的... 详细信息

为评估基于辐射型反射涂层的热控制墙体节能效果,解决相关评测体系缺失问题,建立墙体瞬态传热模型,探究复杂气候交变环境下墙体温度和热流的动态特性,以及辐射换热在被动式制冷过程中的热调控作用,基于热流和墙体传热系数提出一种新的评估模型进行性能评价.结果表明:在室内空调开启情况下,热控制墙体相比于普通墙体,其外表面温度平均下降10.74%,热流提升了281.54%;在夏热冬暖地区,建筑南侧涂覆辐射型反射涂层效果最佳,涂层可以降低建筑全年冷负荷87.8 mj/m2;在夏热冬冷地区,建筑西面涂覆辐射型反射涂层可以降低建筑全年总负荷26.3 mj/m2.所提出的性能评价指标能够刻画热控制墙体一天内的传热过程和传热特性,进而得到墙体的折合传热系数,对指导实际建筑施工、降低建筑全生命周期总能耗有重要意义.

关键词：辐射型反射涂层数值模拟动态特性建筑节能评价指标

植酸/壳聚糖对涤纶/棉混纺织物的协同阻燃整理

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纺织学报 2024年第4期45卷 126-135页

作者：胡自强骆晓蕾魏璐琳刘琳浙江理工大学材料科学与工程学院浙江杭州310018

针对涤纶/棉混纺织物的易燃问题,采用植酸(PA)和壳聚糖(CS)构成膨胀阻燃体系,通过浸渍烘焙法对涤纶/棉混纺织物进行阻燃整理,并对整理前后织物的化学结构、表面形貌、热稳定性、燃烧行为、力学性能及耐水洗性等进行探究。通过工艺调控... 详细信息

针对涤纶/棉混纺织物的易燃问题,采用植酸(PA)和壳聚糖(CS)构成膨胀阻燃体系,通过浸渍烘焙法对涤纶/棉混纺织物进行阻燃整理,并对整理前后织物的化学结构、表面形貌、热稳定性、燃烧行为、力学性能及耐水洗性等进行探究。通过工艺调控与优化,获得最佳阻燃整理工艺:烘焙温度160℃,烘焙时间120 s,CS质量浓度30 g/L,PA质量浓度400 g/L。经过阻燃整理后,所得涤纶/棉混纺织物的极限氧指数值由17.8%上升到28.7%,达到难燃级别;热重结果表明,相较于原涤纶/棉混纺织物,阻燃涤纶/棉混纺织物的分解速率下降,高温热稳定性显著提高,在氮气气氛下,800℃时残炭率提高到25%以上;阻燃涤纶/棉混纺织物的最大热释放速率由原涤纶/棉混纺织物的145.86 kW/m^(2)下降到96.96 kW/m^(2),总热释放量由原涤纶/棉混纺织物的2.75 mj/m^(2)下降到2.06 mj/m^(2);PA和CS在织物表面构成膨胀阻燃涂层,显著提高了织物的阻燃性能。

关键词：涤纶/棉混纺织物壳聚糖植酸阻燃整理生物质膨胀阻燃体系功能性纺织品

基于计算流体动力学方法的两栖飞机规则波中运动特性研究

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哈尔滨工程大学学报 2024年第1期45卷 44-52页

作者：胡开业石林飞周辉毛丽君哈尔滨工程大学船舶工程学院黑龙江哈尔滨150001

针对水陆两栖飞机加速起飞运动过程受波浪干扰问题,本文基于Star-CCM+平台数值模拟技术,引入SST k-ε湍流模型求解RANS方程,VOF方法捕捉自由液面,DFBI模块以及重叠网格技术模拟水上飞机六自由度运动,建立了一套波浪中水陆两栖飞机加速... 详细信息

针对水陆两栖飞机加速起飞运动过程受波浪干扰问题,本文基于Star-CCM+平台数值模拟技术,引入SST k-ε湍流模型求解RANS方程,VOF方法捕捉自由液面,DFBI模块以及重叠网格技术模拟水上飞机六自由度运动,建立了一套波浪中水陆两栖飞机加速滑行起飞运动特性研究方案。以波长和波高为变量,探讨了加速滑行过程中上述变量对水上飞机升沉、纵摇运动响应以及机身重心处垂向加速度的影响规律。结果表明:随着波长增加,飞机升沉运动先增加后缓慢变化,飞机重心垂向加速度、纵摇角加速度和纵摇峰值集中在波长为2~3倍机身长度海况范围内;随着波高增大,飞机升沉、纵摇运动及重心垂向加速度最大值随之增大,且长波中的运动变化量较短波中更大;机翼气动升力数值模拟结果与计算值一致,该方案可用于水陆两栖飞机气动力相关计算。

关键词：水陆两栖飞机纵向稳性加速运动计算流体力学纵摇升沉规则波重叠网格

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