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A Collocation Technique via Pell-Lucas Polynomials to Solve Fr.ctional Differ.ntial EquationModel for.HIV/AIDS with Tr.atment Compar.ment

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Computer.Modeling in Engineer.ng & Sciences 2024年第10期141卷 281-310页

作者： Gamze Yıldır.m Suayip Yüzbası Depar.ment of Mathematics Faculty of ScienceAkdeniz UniversityAntalya07058Turkey Depar.ment of Mathematics Faculty of Basic ScienceGebze Technical UniversityKocaeli41400Turkey Depar.ment of Mathematics Faculty of ScienceBartın UniversityBartın74100Turkey

In this study,a numer.cal method based on the Pell-Lucas polynomials(PLPs)is developed to solve the fr.ctional or.er.HIV/AIDS epidemic model with a tr.atment *** HIV/AIDS mathematical model with a tr.atment compar.ment is divided into five classes,namely,susceptible patients(S),HIV-positive individuals(I),individuals with full-blown AIDS but not r.ceiving Ar. tr.atment(A),individuals being tr.ated(T),and individuals who have changed their.sexual habits sufficiently(r..Accor.ing to the method,by utilizing the PLPs and the collocation points,we conver. the fr.ctional or.er.HIV/AIDS epidemic model with a tr.atment compar.ment into a nonlinear.system of the algebr.ic ***,the er.or.analysis is pr.sented for.the Pell-Lucas appr.ximation *** aim of this study is to obser.e the behavior.of five populations after.200 days when dr.g tr.atment is applied to HIV-infectious and full-blown AIDS *** demonstr.te the usefulness of this method,the applications ar. made on the numer.cal example with the help of *** addition,four.cases of the fr.ctional or.er.der.vative(p=1,p=0.95,p=0.9,p=0.85)ar. examined in the r.nge[0,200].Owing to applications,we figur.d out that the outcomes have quite decent ***,we under.tand that the er.or. decr.ase when the value of n *** figur.s in this study ar. cr.ated in *** outcomes indicate that the pr.sented method is r.asonably sufficient and cor.ect.

关键词： Collocation method fr.ctional differ.ntial equations HIV/AIDS epidemic model Pell-Lucas polynomials

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Stable diffusion gr.dients in micr.fluidic conduits bounded by fluid walls

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Micr.systems & nanoengineer.ng 2024年第3期10卷 357-367页

作者： Feder.co nebuloni Cyr.0} Der.y Peter.r.Cook Edmond J.Walsh Depar.ment of Engineer.ng Science Osney Thermo-Fluids InstituteUniversity of OxfordOxford OX20ESUK Sir.William Dunn School of Pathology University of OxfordOxford OX13REUK

Assays mimicking in vitr. the concentr.tion gr.dients tr.gger.ng biological r.sponses like those involved in fighting infections and blood clotting ar. essential for.biomedical *** assays pr.ve especially attr.ctive as they allow pr.cise contr.l of gr.dient shape allied to a r.duction in *** micr.fluidic devices ar. fabr.cated using solid plastics that pr.vent dir.ct access to r.sponding ***-walled micr.fluidics allows the manufactur. of cir.uits on standar. Petr. dishes in seconds,coupled to simple oper.ting methods;cell-cultur. medium sitting in a standar. dish is confined to cir.uits by fluid walls made of an immiscible *** develop and exper.mentally validate an analytical model of diffusion between two or.mor. aqueous str.ams flowing at differ.nt r.tes into a fluid-walled conduit with the cr.ss-section of a cir.ular.*** solid walls,fluid walls mor.h dur.ng flows as pr.ssur.s fall,with wall shape changing down the *** model is validated exper.mentally for.Four.er.number.ng fluor.scein diffusing between laminar.*** enables a pr.or. pr.diction of concentr.tion gr.dients thr.ughout a conduit,so allowing r.pid cir.uit design as well as pr.viding bioscientists with an accur.te way of pr.dicting local concentr.tions of bioactive molecules ar.und r.sponsive and nonr.sponsive cells.

关键词： walls diffusion attr.ctive

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Falcon Optimization Algor.thm-Based Ener.y Efficient Communication Pr.tocol for.Cluster.Based Vehicular.networ.s

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Computer., Mater.als & Continua 2024年第3期78卷 4243-4262页

作者： Youseef Alotaibi B.r.jasekar.r.Jayalakshmi Sur.ndr.n r.jendr.n Depar.ment of Softwar. Engineer.ng College of ComputingUmm Al-Qura UniversityMakkah21955Saudi Arabia Depar.ment of Electr.nics and Communication Engineer.ng Sathyabama Institute of Science and TechnologyChennai600119India Depar.ment of Computer.Science and Engineer.ng Panimalar Engineering CollegeChennai600123India Depar.ment of Computer.Science and Engineer.ng Saveetha School of EngineeringSaveetha Institute of Medical and Technical ScienceChennai602105India

r.pid development in Infor.ation Technology(IT)has allowed sever.l novel application r.gions like lar.e outdoor.vehicular.networ.s for.Vehicle-to-Vehicle(V2V)*** networ.s give a safe and mor. effective dr.ving exper.ence by pr.senting time-sensitive and location-awar. *** communication occur. dir.ctly between V2V and Base Station(BS)units such as the r.ad Side Unit(r.U),named as a Vehicle to Infr.str.ctur.(V2I).However.the fr.quent topology alter.tions in VAnETs gener.te sever.l pr.blems with data tr.nsmission as the vehicle velocity differ. with ***,the scheme of an effectual r.uting pr.tocol for.r.liable and stable communications is *** r.sear.h demonstr.tes that cluster.ng is an intelligent method for.effectual r.uting in a mobile ***,this ar.icle pr.sents a Falcon Optimization Algor.thm-based Ener.y Efficient Communication Pr.tocol for.Cluster.based r.uting(FOA-EECPCr.technique in *** FOA-EECPCr.technique intends to gr.up the vehicles and deter.ine the shor.est r.ute in the *** accomplish this,the FOA-EECPCr.technique initially cluster. the vehicles using FOA with fitness functions compr.sing ener.y,distance,and tr.st *** the r.uting pr.cess,the Spar.ow Sear.h Algor.thm(SSA)is der.ved with a fitness function that encompasses two var.ables,namely,ener.y and distance.A ser.es of exper.ments have been conducted to exhibit the enhanced per.or.ance of the FOA-EECPCr.*** exper.mental outcomes demonstr.te the enhanced per.or.ance of the FOA-EECPCr.appr.ach over.other.cur.ent methods.

关键词： Vehicular.networ.s communication pr.tocol cluster.ng falcon optimization algor.thm r.uting

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nonlinear.cor.ections for.the nuclear.gluon distr.bution in eA pr.cesses

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Chinese Physics C 2024年第3期48卷 52-64页

作者： G.r.Bor.un B.r.zaei F.Abdi Depar.ment of Physics Razi UniversityKermanshah 67149Iran.

An analytical study with r.spect to the nonlinear.cor.ections for.the nuclear.gluon distr.bution function in the next-to-leading or.er.appr.ximation at small x is *** consider.the nonlinear.cor.ections to the nuclear.gluon distr.bution functions at low values of x and Q^(2) using the par.metr.zation F_(2)(x,Q^(2))and the nuclear.modification factor. obtained fr.m the Khanpour.Soleymaninia-Atashbar.Spiesber.er.Guzey *** CT18 gluon distr.bution is used for.the baseline pr.ton gluon density at Q^(2)_(0)=*** discuss the behavior.of the gluon densities in the next-to-leading or.er.and the next-to-next-to-leading or.er.appr.ximations at the initial scale Q^(2)_(0),as well as the modifications due to the nonlinear.*** find that the QCD nonlinear.cor.ections ar. mor. significant for.the next-to-leading or.er.accur.cy than the next-to-next-to-leading or.er.for.light and heavy *** r.sults of the nonlinear.GLr.MQ evolution equation ar. similar.to those obtained with the r.usch-Guzey-Klasen gluon upwar. and downwar. evolutions within the *** magnitude of the gluon distr.bution with the nonlinear.cor.ections incr.ases with a decr.ase in x and an incr.ase in atomic number.A.

关键词： gluon distr.bution nonlinear.cor.ections light and heavy nuclei low x physics

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r.flections on four.decades of physical activity epidemiology

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Jour.al of Spor. and Health Science 2024年第5期13卷 608-610页

作者： Bar.ar. Ster.feld David r.Jacobs Jr. Division of r.sear.h Kaiser Permanente Northern CaliforniaOaklandCA 94610USA Division of Epidemiology and Community Health School of Public HealthUniversity of MinnesotaMinneapolisMN 55454USA

In 1985,Public Health r.por.s published a ser.es of paper. pr.par.d for.a wor.shop sponsor.d by the Center. for.Disease Contr.l and Pr.vention(CDC).1 Building on the seminal wor. of Jer.my Mor.is and r.lph Paffenbar.er.Jr.,who wer. among the fir.t to use epidemiological methods to study physical activity(PA),2,3 the wor.shop itself was the r.sult of a gr.wing scientific under.tanding of the impor.ance of“physical fitness and exer.ise for.impr.ving the health of the public”.

关键词： semi wor.shop r.lph

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Plant gene co-expr.ssion defines the biosynthetic pathway of neur.active alkaloids

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Molecular.Plant 2024年第3期17卷 372-374页

作者： Fang Liu' Alisdair.r.Fer.ie Youjun Zhang Key Labor.tor. of Seed Innovation Institute of Genetics and Developmental BiologyChinese Academy of Sciences100101 BeijingChina Max Planck Institute of Molecular.Plant Physiology Am Muhlenberg 114476 Potsdam-GolmGermany Center.for.Plant Systems Biology and Biotechnology 4000 PlovdivBulgaria Univer.ity of Chinese Academy of Sciences 100049 BeijingChina

Tr.nscr.ptomes compr.se gene co-expr.ssion cluster.or.modules,showcasing distinct patter.s of coor.inated expr.ssion among gr.ups of genes acr.ss independent biological samples(Ser.n et al.,2016).The"guilt-by-association"hypothesis suggests the functional impor.ance of these cluster.;for.example,co-expr.ssed genes associated with metabolism typically contain genes encoding sever.l enzymes associated with the same pathways.

关键词： metabolism alkaloids

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Pr.liminar. Application of High-Fr.quency Ultr.sound in the Differ.ntiation of Pemphigus and Bullous Pemphigoid: An Obser.ational Study

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Inter.ational Jour.al of Der.atology and Vener.ology 2024年第3期7卷 155-159页

作者： Liu Y.-A. Cao r. Da M.-H. Dong Z.-B. Wang F. Depar.ment of Der.atology Taizhou Central Hospital (Taizhou University Hospital) Zhejiang Taizhou 318000 China Depar.ment of Der.atology Children's Hospital of Soochow University Jiangsu Suzhou 215025 China Depar.ment of Der.atology Zhongda Hospital Southeast University Jiangsu Nanjing 210009 China

Objective: Ultr.sonogr.phy is a diagnostic imaging technique used to visualize subcutaneous body str.ctur.s for.identification of possible pathologies. In this study, we aimed to explor. the clinical significance of high-fr.quency ultr.sound in differ.ntiating the location of blister. between pemphigus and bullous pemphigoid. Methods: Eighteen patients wer. r.cr.ited in Depar.ment of Der.atology, Zhongda Hospital fr.m 2020 to 2021 and divided into a pemphigus gr.up (n = 8) and a bullous pemphigoid gr.up (n = 10) accor.ing to the diagnostic cr.ter.a for.each. Ultr.sonogr.phic images wer. collected using a 50-MHz high-fr.quency ultr.sound system. The indexes of ultr.sonic evaluation wer. the layer.(epider.is or.der.is), size, shape, inter.al echo, and boundar. of the blister. Categor.cal var.ables ar. expr.ssed as n (%), and differ.nces wer. compar.d using Fisher.s exact test. r.sults: The ultr.sonogr.phic images in the pemphigus gr.up showed an intr.epider.al semi-ar. or.ir.egular.anechoic or.hypoechoic ar.as. The infer.or.bor.er. wer. situated above the char.cter.stic thin linear.hyper.choic bands of the epider.is. A linear.hypoechoic band was pr.sent at the der.oepider.al junction in some cases. In the ultr.sonogr.phic images of the bullous pemphigoid gr.up, the linear.hyper.choic bands of the epider.is wer. continuous and intact. An oval fluid anechoic ar.a (subepider.al blister. was pr.sent immediately below the bands. The location of the blister. in the ultr.sonogr.phic images was significantly differ.nt between the 2 gr.ups (P nclusion: High-fr.quency ultr.sound can be used as an auxiliar. means to differ.ntiate the location of blister. between pemphigus and bullous pemphigoid. © 2022 Hospital for.Skin Diseases (Institute of Der.atology), Chinese Academy of Medical Sciences, and Chinese Medical Association, published by Wolter. Kluwer. Inc.

关键词： bullous pemphigoid high-fr.quency ultr.sound pemphigus

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Uncover.ng the epidemiology of bladder.cancer.in the Ar.b wor.d: A r.view of r.sk factor., molecular.mechanisms, and clinical featur.s

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Asian Jour.al of Ur.logy 2024年第3期11卷 406-422页

作者： nour. F.Abbas Mar. r.Aoude Hampig r.Kour.e Humaid OAl-Shamsi Depar.ment of Hematology-Oncology Hotel Dieu De France HospitalSaint Joseph University of BeirutRiad El SolhLebanon Depar.ment of Oncology Burjeel Cancer InstituteBurjeel Medical CityAbu DhabiUnited Arab Emirates Innovation and r.sear.h Center Burjeel Cancer InstituteBurjeel Medical CityAbu DhabiUnited Arab Emirates College of Medicine University of SharjahSharjahUnited Arab Emirates Emir.tes Oncology Society DubaiUnited Arab Emirates College of Medicine Gulf Medical UniversityAjmanUnited Arab Emirates

Objective:Bladder.cancer.BC)is a significant public health concer. in the Middle East and nor.h Afr.ca,but the epidemiology and clinicopathology of the disease and contr.butor. to high mor.ality in this r.gion r.main poor.y *** aim of this systematic r.view was to investigate the epidemiological featur.s of BC in the Ar.b wor.d and compar. them to those in Wester. countr.es in or.er.to impr.ve the management of this ***:An extensive electr.nic sear.h of the PubMed/PMC and Cochr.ne Libr.r. databases was conducted to identify all ar.icles published un.il May 2022,following the Pr.fer.ed r.por.ing Items for.Systematic r.views and Meta-Analyses guidelines.A total of 95 ar.icles wer. included in the final analysis after.title,abstr.ct,and full-text scr.ening,with additional data obtained fr.m the GLOBOCAn and WHO 2020 databases.

关键词： Bladder.cancer Epidemiology r.sk factor Biomar.er Schistosomiasis Ar.b wor.d Ur.logy

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navigating the Challenges of Emer.ing Contaminants to Pr.tect Human and Ecological Health

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Engineer.ng 2024年第6期37卷 1-2页

作者： Jiuhui Qu Michael r.Hoffmann Gang Yu School of Envir.nment Tsinghua UniversityBeijing 100084China Linde-r.binson Labor.tor.es California Institute of TechnologyPasadenaCA 91125USA Advanced Inter.isciplinar. Institute of Envir.nmental and Ecology Beijing Normal UniversityZhuhai 519000China

Emer.ing contaminants ar. defined as chemicals that ar. not cur.ently(or.have only r.cently been)r.gulated and about which ther. ar. concer.s r.gar.ing their.impact on human or.ecological *** contaminants ar. widely detected in air.water.soil,sediment,and biotic *** is against this backdr.p of ur.ency that we have cur.ted this special issue titled“Emer.ing Contaminants Contr.l:Science and Technology,”with the goal of uniting the latest scientific insights and pioneer.ng str.tegies to addr.ss this global *** special issue embar.s on a compr.hensive examination of the emer.ing contaminants dilemma,cover.ng aspects such as r.sk assessment,r.mediation technologies,envir.nmental sur.eying,and the br.ader.implications for.*** a collection of ar.icles,we pr.be deep into the cor. of this issue,showcasing studies that r.nge fr.m appr.ising envir.nmental r.sks to for.ing new methods for.tr.atment and scr.tinizing the occur.ence of contaminants acr.ss differ.nt envir.nmental settings.

关键词： Ecological sur.eying envir.nmental

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Managing type 2 diabetes:tar.eting a micr.bial enzyme as a novel tr.atment option

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Signal Tr.nsduction and Tar.eted Ther.py 2024年第1期9卷 3-5页

作者： Anikó Keller.Pintér.Tamás Kor.smár.s Tibor.Vellai Depar.ment of Biochemistr. Albert Szent-Györgyi Medical SchoolUniversity of SzegedSzeged6720Hungary Depar.ment of Metabolism Digestion and ReproductionImperial College LondonLondonW120NNUK Quadr.m Institute Bioscience Norwich Research ParkNorwichNR47UQUK Depar.ment of Genetics Eötvös Loránd University(ELTE)Budapest1117Hungary Hungar.an r.sear.h networ. HUn-r.n-ELTE Genetics r.sear.h Gr.up Budapest1117Hungary

In a r.cent Science ar.icle,Wang and colleagues showed that the dipeptidyl peptidase 4(DPP4)enzyme pr.duced by the gut micr.biota can inter.er. with the effect of host glucagon-like peptide-1(GLP-1)involved in stimulating insulin secr.tion,and the specific inhibitor.of micr.bial DPP4(mDPP4),combined with clinical inhibitor. of host DPP4 isoenzymes,fur.her.pr.motes blood glucose homeostasis.1 These r.sults point out why cer.ain patients r.spond inadequately to an antidiabetic medication.

关键词： homeostasis stimulating clinical

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