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Energy Management Strategy Considering Multi-time-scale Operational Modes of Batteries for the Grid-connected Microgrids Community

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CSEE Journal of Power and Energy Systems 2020年第1期6卷 111-121页

作者： Xiaowen Xing Lili Xie hongmin meng Xin Guo Lei Yue Josep M.Guerrero Department of Electrical Engineering Northwestern Polytechnical UniversityXi’an 710072China State Grid Information and Telecommunication Group Ltd.Co. Beijing 102211China State Grid Beijing Fengtai Electric Power Supply Company Beijing 100073China China Electric Power Research Institute Beijing 100192China Department of Energy Technology Aalborg UniversityAalborg9220Denmark

The advantages and promoting applications of the microgrids community(MGC)allows for a critical step being taken toward a smart *** energy management strategy(EMS)is essential to intelligently coordinate the operations of the *** paper presents a multi-time-scale EMS consid-ering battery operational modes for grid-connected *** proposed strategy consists of two modules:day-ahead integrated optimization and realtime distributed *** first module aims to minimize the operational cost of the MGC considering battery free-overcharging *** problem is solved by the mixed integer linear programming(MILP)sim-ulating two charging/discharging modes:limited-current mode and constant-voltage *** second module is installed in local MGs to correct the optimizing deviations of the day-ahead static scheduling,which are caused by predicting errors of renewable energy and *** main contribution of this work is integrating the advantages of global optimization of the centralized method and the fast computing speed of the distributed *** results prove the proposed EMS is feasible and *** computing time at each updating step is reduced by 75%on average,which has the potential to be adopted in engineering.

关键词： Day-ahead optimization energy management strategy forecast errors microgrids community realtime compensation strategy

Copper-thioguanine metallodrug with self-reinforcing circular catalysis for activatable MRI imaging and amplifying specificity of cancer therapy

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Science China Chemistry 2020年第7期63卷 924-935页

作者： Haifeng Yuan Yan Zhao Chan Yang Cheng Zhang Yue Yang hongmin meng Shuangyan Huan Guosheng Song Xiaobing Zhang State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China College of Chemistry Zhengzhou UniversityZhengzhou 450001China

For chemotherapy, drug delivery systems often suffer from the inefficient drug loading capability, which usually cause systems toxicity and extra burden to excrete carrier itself. Moreover, the cancer therapeutic efficacy is also greatly limited by the specificity of tumor microenvironment for reactive oxygen species(ROS) based cancer therapeutic strategy(e.g., chemodynamic therapy). Herein, we have developed metal-drug coordination nanoplatform that can not only be responsive to tumor microenvironment but also modulate it, so as to achieve efficient treatment of cancer. Excitingly, by employing small molecule drug(6-thioguanine) as ligand copper ions, we achieve a high drug loading rate(60.1%) and 100% of utilization of metal-drug coordination nanoplatform(Cu-TG). Interestingly, Cu-TG possessed high-efficiently horseradish peroxidase-like, glutathione peroxidase-like and catalase-like activity. Under the tumor microenvironment, Cu-TG exhibited the self-reinforcing circular catalysis that is able to amplify the cellular oxidative stress, inducing notable cancer cellular apoptosis. Moreover, Cu-TG could be activated with glutathione(GSH) and facilitated for GSH triggered 6-TG release, higher selective therapeutic effect toward cancer cells, and GSH activated T1 weight-magnetic resonance imaging. Based on the above properties, Cu-TG exhibited magnetic resonance imaging(MRI) guiding, efficient and synergistic combination of chemodynamic and chemotherapy with self-reinforcing therapeutic outcomes in vivo.

关键词： coordination nanoplatform metallodrug chemodynamic therapy circular catalysis drug delivery

Dual-readout test strips platform for portable and highly sensitive detection of alkaline phosphatase in human serum samples

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Chinese Chemical Letters 2021年第11期32卷 3421-3425页

作者： Juanzu Liu hongmin meng Lin Zhang Shasha Li Juan Chen Yi Zhang Jianjun Li Lingbo Qu Zhaohui Li Institute of Chemical Biology and Clinical Application at the First Affiliated Hospital Zhengzhou Key Laboratory of Functional Nanomaterial and Medical TheranosticCollege of ChemistryZhengzhou UniversityZhengzhou 450001China

In this work,a very simple dual-readout lateral flow test strip(LFTS)platform was developed for sensitive detection of alkaline phosphatase(ALP)based on a portable *** this assay,quantum dots(QDs)conjugated with bovine serum albumin(QDs-BSA)were chosen as fluorescence signal *** the absence of ALP,MnO_(2)nanosheets aggregate on the test line and exhibit an obvious brown color,which can be observed by naked eyes to realize semi-qualitative ***,fluorescence intensity of QDs-BSA can also be effectively quenched by MnO_(2)nanosheets due to inner-filter ***,in the presence of ALP,ALP can catalyze the hydrolysis of ascorbic acid 2-phosphate(AAP)to generate L-ascorbic acid(AA),which can reduce MnO_(2)into Mn^(2+),accompanying with the obvious fluorescence recovery of the *** simply monitoring the change of colorimetric and fluorescent signal on the test line,trace amount of ALP can be quantitatively *** the optimal conditions,measurable evaluation of ALP was reached in a linear range from 1 U/L to 20 U/L with a detection limit of 0.7 U/L based on fluorescence ***,this colorimetric/fluorescent dual-readout assay was successfully applied to monitor ALP in human serum samples,showing its great potential as a point of care biosensor for clinical diagnosis.

关键词： Lateral flow test strip MnO^(2)nanosheets Quantum dots Dual-readout Alkaline phosphatase

Gold nanorod-photosensitizer conjugate with extracellular pH-driven tumor targeting ability for photothermal/photodynamic therapy

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Nano Research 2014年第9期7卷 1291-1301页

作者： Nannan Wang Zilong Zhao Yifan Lv Huanhuan Fan Huarong Bai hongmin meng Yuqian Long Ting Fu Xiaobing Zhang Weihong Tan Molecular Science and Biomedicine Laboratory State Key Laboratory for Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical Engineering College of Biology and Collaborative Research Center of Molecular Engineering for Theranostics Hunan University Changsha 410082 China Department of Chemistry and Department of Physiology and Functional Genomics Center for Research at Bio/nano Interface Shands Cancer Center UF Genetics Institute and McKnight Brain Institute University of Florida Gainesville Florida 32611-7200 USA

Chlorin e6-pHLIPss-AuNRs, a gold nanorod-photosensitizer conjugate containing a pH （low） insertion peptide （pHLIP） with a disulfide bond which imparts extracellular pH （pHe）-driven tumor targeting ability, has been successfully developed for bimodal photodynamic and photothermal therapy. In this bimodal therapy, chlorin e6 （Ce6）, a second-generation photosensitizer （PS）, is used for photodynamic therapy （PDT）. Gold nanorods （AuNRs） are used as a hyperthermia agent for photothermal therapy （PTT） and also as a nanocarrier and quencher of Ce6. pHLIPss is designed as a pile-driven targeting probe to enhance accumulation of Ce6 and AuNRs in cancer cells at low pH. In Ce6- pHLIPss-AuNRs, Ce6 is close to and quenched by AuNRs, causing little PDT effect. When exposed to normal physiological pH 7.4, Ce6-pHLIPs^-AuNRs loosely associate with the cell membrane. However, once exposed to acidic pH 6.2, pHLIP actively inserts into the cell membrane, and the conjugates are translocated into cells. When this occurs, Ce6 separates from the AuNRs as a result of disulfide bond cleavage caused by intracellular glutathione （GSH）, and singlet oxygen is produced for PDT upon light irradiation. In addition, as individual PTT agent, AuNRs can enhance the accumulation of PSs in the tumor by the enhanced permeation and retention （EPR） effect. Therefore, as indicated by our data, when exposed to acidic pH, Ce6-pHLIPss-AuNRs can achieve synergistic PTT/PDT bimodality for cancer treatment.

关键词： photodynamic therapy photothermal therapy gold nanorods targeting acidity peptide

Manganese-Fluorouracil Metallodrug Nanotheranostic for MRI-Correlated Drug Release and Enhanced Chemoradiotherapy

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CCS Chemistry 2021年第4期3卷 1116-1128页

作者： Chan Yang Guosheng Song Haifeng Yuan Yue Yang Yuqi Wang Deju Ye hongmin meng Shuangyan Huan Xiao-Bing Zhang State Key Laboratory for Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082 State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023 College of Chemistry Zhengzhou UniversityZhengzhou 450001

For cancer therapy,drug delivery systems are often limited by insufficient drug loading capacity,which usually results in systemic toxicity and heavy metabolic burden to excrete the ***,we reported a“one-pot”method for constructing metal(Mn^(2+))–fluorouracil(FU)-coordinated nanotheranostics(Mn-FU)by self-assembly of FU(as bridging ligands)and Mn^(2+)(as metal nodes)through Mn–N/O coordination ***,owing to the effective coordination between Mn and FU,Mn-FU exhibits high drug loading efficacy(47.7 wt%),encapsulation efficacy(82.6%),and relatively large yield(1 g/pot).In acidic tumor microenvironments,efficient release of FU and Mn^(2+)is realized because of nitrogen *** released FU and Mn^(2+)from Mn-FU are used for chemotherapy and turn on magnetic resonance imaging(MRI),respectively,achieving MRI-correlated drug *** PEG modification,Mn-FU displays high tumor homing ability via enhanced permeability and retention effects and quick renal clearance owing to the disassembly in acidic biological *** a result,Mn-FU substantially enhances the synergistic effects of ***,the systemic toxic side effects of free FU-based chemoradiotherapy were greatly reduced through this *** strategy offers a facile way to construct metallodrug nanotheranostics for efficient cancer theranostics.

关键词： coordination-driven self-assembly metallodrug nanotheranostics magnetic resonance imaging synergetic chemoradiotherapy

采用梯度估计的风力发电系统最优转矩最大功率点追踪效率优化

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中国电机工程学报 2015年第10期35卷 2367-2374页

作者：刘吉臻孟洪民胡阳新能源电力系统国家重点实验室(华北电力大学) 北京市昌平区102206

风轮大转动惯量导致最优转矩最大功率点追踪(maximum power point tracking,MPPT)控制方法暂态时间过长,效率降低。通过研究风力发电系统(wind turbine generator system,WTGS)工作机理,对问题及原因作具体分析,并设计基于梯度估计的最... 详细信息

风轮大转动惯量导致最优转矩最大功率点追踪(maximum power point tracking,MPPT)控制方法暂态时间过长,效率降低。通过研究风力发电系统(wind turbine generator system,WTGS)工作机理,对问题及原因作具体分析,并设计基于梯度估计的最优转矩补偿器,对电磁转矩给定值进行补偿,以减小大转动惯量对风轮转速变化的影响。通过建立兆瓦级双馈WTGS小信号模型及系统闭环传递函数,分析系统闭环极点、阶跃响应曲线及频率特性。小信号模型分析及仿真结果表明,改进后的方法具有良好的系统稳定性及动态特性,暂态过程时间小,兼有经典最优转矩法稳定性和叶尖速比法快速性等部分优点,风能转化率较高。

关键词：风力发电系统最大功率点追踪转动惯量最优转矩控制小信号模型

含异步变速风机的风电场一次调频等值建模与仿真

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电力系统自动化 2019年第23期43卷 185-192页

作者：姚琦刘吉臻胡阳孟洪民华北电力大学控制与计算机工程学院北京市102206 新能源电力系统国家重点实验室(华北电力大学) 北京市102206 国网信息通信产业集团有限公司北京市102211

风机参与系统一次调频目前已成为各国电网对风机并网的基本要求,但是适用于预测控制等算法的大型风电场频率响应动态特性数学描述尚未有充分研究。文中提出了参与调频前运行于最大功率点跟踪模式下的异步变速风机参与一次调频时的全风... 详细信息

风机参与系统一次调频目前已成为各国电网对风机并网的基本要求,但是适用于预测控制等算法的大型风电场频率响应动态特性数学描述尚未有充分研究。文中提出了参与调频前运行于最大功率点跟踪模式下的异步变速风机参与一次调频时的全风况出力响应模型,基于小信号增量法获得了不同工况下出力响应的线性化描述,与风机非线性模型对比验证了所提线性化模型的有效性和准确性。此外,在单机线性化模型基础上,基于间隙度量计算将特性相似的风机进行聚类,建立了风电场出力响应等值模型。仿真结果表明,所提等值模型在降低风电场调频模型复杂度的前提下保证了风电场频率响应特性的逼近精度。

关键词：一次调频异步变速风机线性化模型间隙度量等值模型

Undisturbed Switching Strategy Based on Gain Self-regulation for Wind Turbine Generation System

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Optimal Price Incentive Strategy Based on Chance-constrained Programming for Virtual Power Plants Participating in Demand Response

第32届中国控制与决策会议

作者： hongmin meng Di Liu Dekun Lv Zhenan Xu Fang Li Qi Yao State Grid Information and Telecommunication Group Co. Ltd. Shandong Institute of Space Electronic Technology North China Electric Power University

This paper proposes a novel undisturbed switching strategy based on gain self-regulation for wind turbine generation system（WTGS） to restrain extra power fluctuations and mechanical loads caused during the controller switching process between full-load region and partial-load region. The switching characteristics near rated wind speed is firstly analyzed, and theoretical foundation of gain regulation is discussed. Then the gain self-regulation method based on Fourier transform is presented to optimize the switching performance. The simulation results based on FAST reveal that, the proposed switching strategy reduces output power fluctuations and mechanical loads significantly, which is also friendly to power grid and wind turbine devices.

关键词： Wind turbine generation system Undisturbed switching Power fluctuations Mechanical loads FAST

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Optimal Price Incentive Strategy Based on Chance-constrained...