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氟尿嘧啶与常用止吐药在Y型输液通路中的相容性

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医药导报 2021年第10期40卷 1408-1411页

作者：何光照王玲娜邓玉琴丁建薛宏波江苏省常州市肿瘤医院、苏州大学附属常州肿瘤医院药剂科临床试验机构办公室常州213032 江苏省常州市食品药品监督检验中心常州213022

目的研究氟尿嘧啶与常用止吐药在Y型输液通路中的相容性,以评价临床配伍用药的合理性和可行性。方法模拟临床实际Y型输液通路,在室温不避光环境下,向氟尿嘧啶以0.9%氯化钠注射液或5%葡萄糖注射液配置后两种临用前药液中,分别加入临床单... 详细信息

目的研究氟尿嘧啶与常用止吐药在Y型输液通路中的相容性,以评价临床配伍用药的合理性和可行性。方法模拟临床实际Y型输液通路,在室温不避光环境下,向氟尿嘧啶以0.9%氯化钠注射液或5%葡萄糖注射液配置后两种临用前药液中,分别加入临床单次常用量的一种止吐药(盐酸昂丹司琼、盐酸格拉司琼、盐酸托烷司琼、盐酸阿扎司琼、盐酸帕洛诺司琼或地塞米松磷酸钠)临用前药液,等体积混匀后,共得12种配伍液。对配伍液在配置后0,0.5,1,2和4 h的外观性状、pH值、氟尿嘧啶浓度进行考察。结果氟尿嘧啶与盐酸昂丹司琼混合后即产生白色浑浊,其他10种配伍液在4 h内均保持无色、澄清,未见气泡、紊状物和沉淀等产生,不溶性微粒、pH值和配伍液中氟尿嘧啶浓度均符合配伍要求。结论在室温不避光情况下,氟尿嘧啶与盐酸昂丹司琼在Y型输液通路中配伍不相容,与其他5种止吐药配伍相容。

关键词：氟尿嘧啶止吐药 Y型输液通路相容性

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垫料生物炭对Cd^(2+)的吸附性能

环境工程学报 2016年第11期10卷 6655-6661页

作者：王俊超郑凯琪俞筱妍薛红波李建辉尹微琴王小治扬州大学环境科学与工程学院扬州225127 江苏省有机固体废弃物资源化协同创新中心南京210095

以发酵床废弃垫料和秸秆为原料,采用限氧热解法制备不同温度(300、400和500℃)下的垫料生物炭(D300、D400和D500)和秸秆生物炭(S300、S400和S500),通过X-ray能谱仪、扫描电镜、傅里叶变换红外光谱仪等手段表征其物理化学性质,研究不同... 详细信息

以发酵床废弃垫料和秸秆为原料,采用限氧热解法制备不同温度(300、400和500℃)下的垫料生物炭(D300、D400和D500)和秸秆生物炭(S300、S400和S500),通过X-ray能谱仪、扫描电镜、傅里叶变换红外光谱仪等手段表征其物理化学性质,研究不同吸附时间、Cd^(2+)浓度和初始pH下垫料生物炭对Cd^(2+)的吸附性能,并与秸秆生物炭进行比较。结果表明,D300和D400的吸附过程较符合准二级动力学模型,D500的吸附过程更符合颗粒内扩散模型,吸附时间以30 h为宜;垫料生物炭对Cd^(2+)的等温吸附实验更符合Freundlich模型,400℃制备的垫料生物炭对Cd^(2+)的吸附效果最好;D300和D400对Cd^(2+)的吸附能力受pH的影响较大,D500对Cd^(2+)的吸附能力受pH的影响较小,pH在4.5~7.5之间吸附效果较好。秸秆生物炭吸附Cd^(2+)到表观平衡所用的时间在20 h左右,而最大吸附量比垫料生物炭多2.727 mg·g-1。

关键词：生物炭垫料秸秆吸附镉

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电力企业信用度综合智能评分及风险等级评价

微型电脑应用 2023年第2期39卷 111-114页

作者：庄友淳薛宏波朱晓明国网青海省电力公司西宁供电公司青海西宁810003 国网西宁供电公司易创数字化实验室青海西宁810003

针对电力企业信用度性能差,风险评估能力差等问题,提出了一种新型的管理方法,构建了一种新型的综合智能评分架构方案。该方案能够融合多种数据信息,实现电力企业信用度综合智能评分。在该电力企业信用度综合智能评分系统的基础上,设计... 详细信息

针对电力企业信用度性能差,风险评估能力差等问题,提出了一种新型的管理方法,构建了一种新型的综合智能评分架构方案。该方案能够融合多种数据信息,实现电力企业信用度综合智能评分。在该电力企业信用度综合智能评分系统的基础上,设计了改进型模糊评价方法,该方法融合了DA-BP神经网络模型,又通过卷积分计算,提高了电力企业信用度评估能力。通过试验,本研究的方法评估精度高,性能稳定可靠。

关键词：企业信用度 DA-BP神经网络模型卷积分计算改进型模糊评价方法风险评估

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头孢氨苄在磷酸盐缓冲液中的单扫描极谱法

中南民族大学学报（自然科学版） 2010年第3期29卷 22-24页

作者：王炎英薛红波牙禹詹国庆中南民族大学化学与材料科学学院国家民委分析化学重点实验室武汉430074 广西壮族自治区甘蔗研究所南宁530007

采用单扫描极谱法研究了头孢氨苄在pH 7.4的KH2PO4-K2HPO4缓冲溶液中的极谱行为,发现在-1.2V附近产生一个灵敏的还原峰.还原峰峰电流与头孢氨苄的浓度分别在2.7×10-7～2.7×10-6mol/L和2.7×10-6～1.0×10-3mol/L范围存在良好的线性关... 详细信息

采用单扫描极谱法研究了头孢氨苄在pH 7.4的KH2PO4-K2HPO4缓冲溶液中的极谱行为,发现在-1.2V附近产生一个灵敏的还原峰.还原峰峰电流与头孢氨苄的浓度分别在2.7×10-7～2.7×10-6mol/L和2.7×10-6～1.0×10-3mol/L范围存在良好的线性关系,检测限为2.7×10-8mol/L(S/N=3).用于药片中头孢氨苄测量,加入回收率为94.0%～102.0%.

关键词：头孢氨苄单扫描极谱法药物分析

Operation and Force Analysis of the Guide Wire in a Minimally Invasive Vascular Interventional Surgery Robot System

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Chinese Journal of Mechanical Engineering 2015年第2期28卷 249-257页

作者： YANG xue WANG hongbo SUN Li YU Hongnian Parallel Robot and Mechatronic System Laboratory of Hebei Province Yanshan University School of Mechanical Engineering University of Jinan Key Laboratory of Advanced Forging & Stamping Technology and Science of Ministry of Education Yanshan University Faculty of Science and Technology Bournemouth University

To develop a robot system for minimally invasive surgery is significant,however the existing minimally invasive surgery robots are not applicable in practical operations,due to their limited functioning and weaker perception.A novel wire feeder is proposed for minimally invasive vascular interventional *** is used for assisting surgeons in delivering a guide wire,balloon and stenting into a specific lesion *** contrasting those existing wire feeders,the motion methods for delivering and rotating the guide wire in blood vessel are described,and their mechanical realization is presented.A new resistant force detecting method is given in *** change of the resistance force can help the operator feel the block or embolism existing in front of the guide *** driving torque for rotating the guide wire is developed at different *** the CT reconstruction image and extracted vessel paths,the path equation of the blood vessel is *** the shapes of the guide wire outside the blood vessel,the whole bending equation of the guide wire is *** is a risk criterion in the delivering *** process can make operations safer and man-machine interaction more reliable.A novel surgery robot for feeding guide wire is designed,and a risk criterion for the system is given.

关键词： minimally invasive wire feeder force analysis moment of inertia risk criterion

Impermeability of Y_3Al_5O_(12) ceramic against molten glassy calcium-magnesium-alumina-silicate

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Chinese Journal of Aeronautics 2018年第12期31卷 2306-2311页

作者： Zhaolu xue Yue MA Shengkai GONG hongbo GUO School of Materials Science and Engineering Beihang UniversityBeijing 100083China Key Laboratory of High-Temperature Structure Materials and Coatings Technology (Ministry of Industry and Information Technology) Beihang UniversityBeijing 100083China

Degradation of thermal barrier coatings(TBCs) caused by calcium-magnesium-aluminasilica(CMAS) glassy penetration is becoming an urgent issue for TBCs industrial applications. In this work, yttrium aluminum garnet(YAlO, YAG) nano-powders were synthesized through a chemical co-precipitation route. The resistance of YAG ceramic to glassy CMAS infiltration at1250 °C was evaluated. YAG ceramic bulk sintered at 1700 °C for 10 h was comprised of a single garnet-type YAlOphase. The molten CMAS glass was suppressed on the surface of the YAG ceramic at 1250 °C. A chemical reaction between YAG and the molten CMAS glass did not occur at 1250 °C for 24 h, suggesting that YAG could act as an impermeable material against glassy CMAS deposits in the TBC field.

关键词： Calcium-magnesium-alu mina-silicate(CMAS) Ceramics Thermal barrier coating Yttrium aluminum garnet Zirconia

Progress in study on endocrine disrupting pesticides (EDPs) in aquatic environment

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Chinese Science Bulletin 2005年第20期50卷 2257-2266页

作者： xue Nandong WANG hongbo XU Xiaobai State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China Department of Environmental Sciences and Engineering Hunan Agricultural University Changsha 410128 China

Background on the generation of the problems of endocrine disrupting pesticides (EDPs) in aquatic environment, characteristics of EDPs, adverse effects and their effect mechanism of EDPs on human and wildlife, the transportation and degradation pathways of EDPs in water and analysis methods of EDPs in water were reviewed. The importance of EDPs in water should be attached to adverse effects on wildlife and human health. It was advised to estab- lish research programs on EDPs in aquatic environment es- pecially in water supply source.

关键词：水生环境内分泌紊乱杀虫剂 EDPs 人类健康化学物质

荧光增白剂CXT和CBS的物理化学性质及细胞毒性

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山西医科大学学报 2020年第11期51卷 1193-1200页

作者：姚苏霞薛红波王真祥杜江锋山西医科大学医学影像学院太原030001 山西省疾病预防控制中心卫生检验二科山西青山化工有限公司研发部

目的研究荧光增白剂CXT和CBS的物理化学性质及其对人支气管上皮细胞16HBE和人皮肤角质细胞HaCaT的生物安全性。方法利用高效液相色谱仪检测紫外吸光度反映荧光增白剂的纯度,利用动态光散射仪检测荧光增白剂分子的尺寸和电荷,使用分光测... 详细信息

目的研究荧光增白剂CXT和CBS的物理化学性质及其对人支气管上皮细胞16HBE和人皮肤角质细胞HaCaT的生物安全性。方法利用高效液相色谱仪检测紫外吸光度反映荧光增白剂的纯度,利用动态光散射仪检测荧光增白剂分子的尺寸和电荷,使用分光测色仪检测荧光增白剂对棉布的增白效果。以人支气管上皮细胞16HBE和人皮肤角质细胞HaCaT为研究对象,利用酶标仪和MTT试剂检测细胞液在490 nm处的吸光度反映细胞活力,利用显微镜观察细胞膜表面形态变化,利用流式细胞仪检测细胞液荧光强度反映细胞凋亡情况。通过设立空白对照组,50,100,200μg/ml荧光增白剂CXT和CBS组,研究荧光增白剂CBS和CXT对这两种细胞的毒理学效应。结果荧光增白剂CXT和CBS主要成分的纯度在97%左右,对棉布均有良好的增白强度,分别达到99.92%和99.69%,其表面具有负电荷和纳米级的分子尺寸。研究结果显示,与空白对照组的细胞相比,荧光增白剂CBS在100μg/ml时16HBE和HaCaT细胞活力分别降低到80.0%和90.1%,荧光增白剂CXT在100μg/ml时16HBE和HaCaT细胞活力分别降低到88.5%和93.2%,但这两种细胞形态均未发生明显变化。细胞凋亡的流式分析结果也证实,即使在200μg/ml的荧光增白剂溶液作用下,细胞也未发生明显的凋亡。结论荧光增白剂CXT和CBS表面的负电荷使它们具有良好的水溶性,纳米级的分子尺寸使其染色效果更为持久。在日常使用情况下(洗涤剂中的荧光增白剂的添加量为4-40μg/ml),荧光增白剂中无论是CBS还是CXT均不会对呼吸道或者皮肤表面的细胞造成毒性损伤,具有良好的生物安全性。

关键词：荧光增白剂CXT 荧光增白剂CBS 细胞活力细胞凋亡毒理学

Space advanced technology demonstration satellite

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Science China(Technological Sciences) 2024年第1期67卷 240-258页

作者： ZHANG XiaoFeng CHEN Wen ZHU XiaoCheng MENG Na HE JunWang BI XingZi ZHANG YongHe SHI Qi LI Fei LIU Rui FENG ZhengGong LIU Liu LI JinSong WU HaiChen XU DongXiao LI TaiJie HUANG JiangJiang LIU Shuo LI TianTong YU XianSheng GAO Yang ZHOU Heng BAN HanYu ZHANG YanLi ZHANG YueTing YANG YingQuan HE Tao DUAN XuLiang CHEN Xin WANG YaMin SUN AnTai ZHANG KuoXiang SUN Ying WANG YaoBin FAN ChengCheng XIONG ShaoLin LI XinQiao WEN XiangYang LING ZhiXing SUN XiaoJin ZHANG Chen BAI XianYong WANG ZhanShan DENG YuanYong TIAN Hui YANG JianFeng xue hongbo SANG Peng LIU JinGuo ZHENG HuiLong ZHU Xiang HE JianWu LI Hui XU LuXiang XU ShuYan CHEN WenWu LIU ZhenDong WANG ZhaoLi MAO XiangLong GAO Rong LI ZongXuan DING GuoPeng WANG XinYu DOU RunJiang WENG LuBin LUO Hao WANG YaPing LIANG XianFeng FANG ZiRuo Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 201203China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China National Astronomical Observatory of China Beijing 100101China Shanghai Institute of Technical Physics Chinese Academy of SciencesShanghai 200083China Institute of Precision Optical Engineering School of Physics Science and EngineeringTongji UniversityShanghai 200092China School of Earth and Space Sciences Peking UniversityBeijing 100871China Xi’an Institute of Optics and Precision Mechanics Chinese Academy of SciencesXi’an 710119China National Space Science Center Chinese Academy of SciencesBeijing 100190China Shenyang Institute of Automation Chinese Academy of SciencesShenyang 110016China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100190China Institute of Mechanics Chinese Academy of SciencesBeijing 100190China Shanghai Institute of Organic Chemistry Chinese Academy of SciencesShanghai 200032China Hangzhou Institute for Advanced Study University of Chinese Academy of SciencesHangzhou 310024China Nanyang Technological University Singapore 569830Singapore Dalian Institute of Chemical Physics Chinese Academy of SciencesDalian 116023China Technical Institute of Physics and Chemistry Chinese Academy of SciencesBeijing 100049China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Institute of Semiconductors Chinese Academy of SciencesBeijing 100083China Institute of Automation Chinese Academy of SciencesBeijing 100190China School of Aeronautics and Astronautics Zhejiang UniversityHangzhou 310058China

The Space Advanced Technology demonstration satellite(SATech-01),a mission for low-cost space science and new technology experiments,organized by Chinese Academy of Sciences(CAS),was successfully launched into a Sun-synchronous orbit at an altitude of~500 km on July 27,2022,from the Jiuquan Satellite Launch *** as an experimental platform for space science exploration and the demonstration of advanced common technologies in orbit,SATech-01 is equipped with 16 experimental payloads,including the solar upper transition region imager(SUTRI),the lobster eye imager for astronomy(LEIA),the high energy burst searcher(HEBS),and a High Precision Magnetic Field Measurement System based on a CPT Magnetometer(CPT).It also incorporates an imager with freeform optics,an integrated thermal imaging sensor,and a multi-functional integrated imager,*** paper provides an overview of SATech-01,including a technical description of the satellite and its scientific payloads,along with their on-orbit performance.

关键词： SATech-01 spacecraft design scientific instruments on-orbit performance

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