检索结果-南通市图书馆

Eff ect of post-rewarming fever after targeted temperature management in cardiac arrest patients: a systematic review and meta-analysis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2023年第3期14卷 217-223页

作者： Guang-qi Guo Yan-nan Ma Shuang Xu hong-rong zhang Peng Sun Department of Emergency Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

BACKGROUND:Targeted temperature management(TTM),as a therapeutic temperature control strategy for cardiac arrest(CA),is recommended by ***,the relationship between postrewarming fever(PRF)and the prognosis of CA patients is ***,we aim to summarize the studies regarding the infl uence of PRF on patients with ***:EMBASE,PubMed,and Cochrane Central databases were searched from inception to March 13,*** clinical trials(RCTs)and cohort studies on PRF in CA patients were *** to the heterogeneity,the meta-analysis was performed using a random eff ects model or fi xed eff ects model to calculate the pooled odds ratios(ORs)and corresponding 95%confi dence intervals(CIs).The outcome data were unfavorable neurological outcome and ***:The meta-analysis included 11 observational studies involving 3,246 *** results of the meta-analysis show that PRF(body temperature>38.0℃)has no eff ect on the neurological outcome of CA patients(OR 0.71,95%CI 0.43–1.17,I282%)and has a signifi cant relationship with lower mortality(OR 0.63;95%CI 0.49–0.80,I239%).However,PRF with a stricter defi nition(body temperature>38.5℃)was associated with worse neurological outcome(OR 1.44,95%CI 1.08–1.92,I245%)and higher mortality(OR 1.71,95%CI 1.25–2.35,I247%).CONCLUSION:This study suggests that PRF>38.0℃ may not affect the neurological outcome and have a lower mortality in CA patients who completed ***,PRF>38.5℃ is a potential prognostic factor for worse outcomes in CA patients.

关键词： Cardiac arrest Target temperature management Post-rewarming fever Rebound hyperthermia

Removal of cadmium using MnO_2 loaded D301 resin

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2007年第6期19卷 652-656页

作者： ZHU Zhi-liang MA hong-mei zhang rong-hua GE Yuan-xin ZHAO Jian-fu Key Laboratory of Yangtze Aquatic Environment of Ministry of Education State Key Laboratory of Pollution Control and Resource Reuse Tongji University Shanghai 200092 China

MnO2 loaded weak basic anion exchange resin D301 （Anion exchange resin, macroreticular weak basic styrene） as adsorbent has been prepared and applied to the removal of cadmium. The adsorption characteristics have been investigated with respect to effect of pH, equilibrium isotherms, removal kinetic data, and interference of the coexisting ions. The results indicated that the Cd^2＋ could be efficiently removed using MnO2 loaded D301 resin in the pH range of 3-8 from aqueous solutions with the co-existence of high concentration of alkali and alkaline-earth metals ions. The saturate adsorption capacity of the Cd^2＋ was 77.88 mg/g. The adsorption process followed the pseudo first-order kinetics. The equilibrium data obtained in this study accorded excellently with the Langmuir adsorption isotherm.

关键词： cadmium kinetics adsorption loaded resin removal

The relationship between serum amyloid A and apolipoprotein A-I in high-density lipoprotein isolated from patients with coronary heart disease

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2013年第19期126卷 3656-3661页

作者： WANG Dong-xue LIU hong YAN Li-rong zhang Ye-ping GUAN Xiao-yuan XU Zhi-min JIA You-hong LI Yi-shi zKey Laboratory of Clinical Trial Research in Cardiovascular Drugs Ministry of Health State Key Laboratory of Cardiovascular DiseasesFuwai Hospital National Center for Cardiovascular DiseasesPeking Union Medical College and Chinese Academy of MedicalSciences Beijing 100037China

Background Alteration in the protein composition of high-density lipoprotein （HDL） has been proposed as a mechanism for the development of coronary heart disease （CHD）.In HDL,an increase in serum amyloid A protein （SAA） accompanying the decrease in apolipoprotein A-I （apoA-I） has been found during the acute inflammation ***,whether this phenomenon persists in CHD patients,a disease related to inflammation,is *** purpose of the present study was to explore the relationship between SAA and apoA-I in HDL isolated from CHD *** Overall,98 patients with confirmed stable CHD and 90 control subjects matched for age and gender were enrolled in this case-control *** bromide （KBr） density gradient ultracentrifugation was used to isolate HDL from *** levels of SAA and apoA-I in the HDL samples were detected by enzyme-linked immunosorbent assay ***＇s correlation and general linear models were used in the *** Compared with controls,patients with CHD had a significant decrease in the amount of apoA-I （（14.21±8.44） μg/ml vs.（10.95±5.95） μg/ml,P =0.003） in HDL and a significant increase in the amount of log SAA （1.21±0.46 vs.1.51±0.55,P 〈0.00001）.Differences were independent of age,body mass index （BMI）,HDL cholesterol （HDL-C）,and other *** independently and statistically significant positive correlation between log SAA and apoA-I in HDL was observed only in the CHD group （β =2.0,P =0.026）.In the general linear model,changes in Iog（SAA）,age,age2,gender,BMI and HDL-C could explain a statistically significant 43% of the variance in *** This study provides direct evidence for the first time that there was an independent positive correlation between log SAA and apoA-I in the HDL of CHD patients,indicating the alteration of protein composition in ***,the question of whether this alteration in HDL is associated with impairment of HDL functions requires further research.

关键词： coronary heart disease lipoproteins high-density lipoprotein serum amyloid A protein apolipoprotein A-I

Nonlinear Observer Design and Application

在线全文

学校读者我要写书评

暂无评论

Nonlinear Observer Design and Application

Knight不确定环境下Lévy市场中的期权定价

1998年中国控制会议

作者： Yiguang hong rong zhang Jingqing Han Lab of Systems and Control, Institute of Systems Science, Academia Sinica, Beijing 100080

＜正＞In this paper, a nonlinear observer design method is proposed for control systems. The strict theoretic results are presented only for linear systems, but, in fact, the method is very effective in nonlinear case... 详细信息

关键词： nonlinear observer robustness application in robot control.

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

数学的实践与认识 2016年第20期46卷 87-92页

作者：黄虹王向荣张勇山东科技大学信息科学与工程学院山东青岛266590 山东科技大学数学与系统科学学院山东青岛266590

研究了Knight不确定环境下的Lévy型金融市场.假设标的股票价格服从Lévy过程,借助Lévy-Laplace指数建立了欧式期权的动态定价模型,得到了定价区间,并针对Lévy纯跳过程给出了模型的显示解.最后,利用数值分析方法,研究了Knight不确定... 详细信息

研究了Knight不确定环境下的Lévy型金融市场.假设标的股票价格服从Lévy过程,借助Lévy-Laplace指数建立了欧式期权的动态定价模型,得到了定价区间,并针对Lévy纯跳过程给出了模型的显示解.最后,利用数值分析方法,研究了Knight不确定性参数对欧式看涨期权定价区间的重要影响.

关键词： Knight不确定性 Lévy过程 Lévy-Laplace指数期权定价

Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2955-2968页

作者： Wei zhang Yubao Lu Ruoqi Shen Yingjie Wu Chenrui Liu Xingxing Fang Liangming zhang Bin Liu Limin rong Department of Spine Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina

Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord ***,the precise mechanism remains *** investigate the molecular mechanisms by which microglia regulate the neuroinflammatory response to spinal cord injury,we performed single-cell RNA sequencing dataset analysis,focusing on changes in microglial *** found that the MG1 subpopulation emerged in the acute/subacute phase of spinal cord injury and expressed genes related to cell pyroptosis,sphingomyelin metabolism,and neuroinflammation at high ***,we established a mouse model of contusive injury and performed intrathecal injection of siRNA and molecular inhibitors to validate the role of ceramide synthase 5 in the neuroinflammatory responses and pyroptosis after spinal cord ***,we established a PC12-BV2 cell co-culture system and found that ceramide synthase 5 and pyroptosis-associated proteins were highly expressed to induce the apoptosis of neuron *** ceramide synthase 5 expression in a mouse model of spinal cord injury effectively reduced ***,ceramide synthase 5-induced pyroptosis was dependent on activation of the NLRP3 signaling *** ceramide synthase 5 expression in microglia in vivo reduced neuronal apoptosis and promoted recovery of neurological ***2g7 formed a“bridge”between sphingolipid metabolism and ceramide synthase 5-mediated cell death by inhibiting the NLRP3 signaling ***,these findings suggest that inhibiting ceramide synthase 5 expression in microglia after spinal cord injury effectively suppressed microglial pyroptosis mediated by NLRP3,thereby exerting neuroprotective effects.

关键词： ceramide synthase 5 gasdermin D microglia neuroinflammation NLRP3 nuclear factor kappa B Pla2g7 pyroptosis sphingomyelin metabolism spinal cord injury

Flexible Graphene Field‑Effect Transistors and Their Application in Flexible Biomedical Sensing

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 252-313页

作者： Mingyuan Sun Shuai Wang Yanbo Liang Chao Wang Yunhong zhang hong Liu Yu zhang Lin Han Institute of Marine Science and Technology Shandong UniversityQingdao 266237ShandongPeople’s Republic of China State Key Laboratory of Crystal Materials Shandong UniversityJinan 250100ShandongPeople’s Republic of China School of Integrated Circuits Shandong UniversityJinan 250100ShandongPeople’s Republic of China Shandong Engineering Research Center of Biomarker and Artificial Intelligence Application Jinan250100ShandongPeople’s Republic of China

Flexible electronics are transforming our lives by making daily activities more *** to this innovation are field-effect transistors(FETs),valued for their efficient signal processing,nanoscale fabrication,low-power consumption,fast response times,and ***,known for its exceptional mechanical properties,high electron mobility,and biocompatibility,is an ideal material for FET channels and *** combination of graphene and FETs has given rise to flexible graphene field-effect transistors(FGFETs),driving significant advances in flexible electronics and sparked a strong interest in flexible biomedical ***,we first provide a brief overview of the basic structure,operating mechanism,and evaluation parameters of FGFETs,and delve into their material selection and patterning *** ability of FGFETs to sense strains and biomolecular charges opens up diverse application *** specifically analyze the latest strategies for integrating FGFETs into wearable and implantable flexible biomedical sensors,focusing on the key aspects of constructing high-quality flexible biomedical ***,we discuss the current challenges and prospects of FGFETs and their applications in biomedical *** review will provide valuable insights and inspiration for ongoing research to improve the quality of FGFETs and broaden their application prospects in flexible biomedical sensing.

关键词： Flexible Graphene Field-effect transistor Wearable Implantable Biosensor

Technology of infrared image process based on difference between continuous frames

在线全文

学校读者我要写书评

暂无评论

Technology of infrared image process based on difference bet...

Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

Photonics Asia 2004;Sensors and Imaging

作者： ZHUO hong-yan, zhang rong, YOU An-qing, Song Ying-song Institute of Applied Electronics, CAEP, P.O. Box 919-1011, Mianyang Sichuan.621900, China

While using long wave FPA infrared detector to detect target, there are some faults in the infrared detector such as speckles add to infrared image we shot. The inherent faults of the infrared detector are solved by means based on difference between the two continuous frames. By setting different grades of gray value, the noise such as all speckles and mostly background in the two continuous frames is eliminated. Consequently, The area where the target moved is picked up.

关键词： infrared image, difference between continuous frames, motion compensation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao Jing-Wen Li Hui Ye Xue-Zhi zhang Jian-Xiang Liu hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly