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Classification of breast microcalcifications: radiological-pathological correlation

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Chinese Medical Journal 2005年第17期118卷 1429-1435页

作者： SUN Zhe liang hong-wei xu Hui-mian Department of Oncological Surgery First Affiliated Hospital of China Medical University Shenyang 110001 China

Microcalcifications play a very important role in detection of breast cancer, especially early stage breast cancer. However, ambiguity still exists in understanding the relationship between radiological and pathological characteristics of microcalcifications. The definitive indication of a biopsy has not been established. The purpose of this study is to evaluate the relationship of classification of breast microcalcifications using full-field digital mammography to the pathological characteristics.

关键词： calcinosis breast neoplasms mammography

Brain atrophy in a patient with mitochondrial DNA G8363A mutation

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Chinese Medical Journal 2019年第17期132卷 2141-2142页

作者： hong-liang xu Ya-Jun Lian Xin Chen Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China

To the Editor: Mitochondrial diseases are a common group of human genetic diseases that can occur at any decade of life. Mitochondrial DNA (mtDNA) mutations are responsible for most adult-onset mitochondrial diseases.[1] There are over 260 known pathogenic mutations in mtDNA.[2] In the last two decades, a large number of pathogenic mutations of mtDNA have been reported, which associate with a wide spectrum of clinical features.[3]

关键词： There are In the last a large number of

Hysteroscopy and directed biopsy in the diagnosis of endometrial carcinoma

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Chinese Medical Journal 2010年第24期123卷 3524-3528页

作者： ZHU hong-lan liang xu-dong WANG Jian-liu CUI Heng WEI Li-hui Department of Gynecology and Obstetrics Peking University People's Hospital Beijing 100044 China

Background Diagnostic hysteroscopy and directed biopsy has been widely used to evaluate abnormal uterine bleeding. We aimed to explore the value of hysteroscopy and directed biopsy in the diagnosis of endometrial *** Two hundred and eighty-seven patients with endometrial carcinoma who were treated in Beijing University People＇s Hospital, Beijing, China were distributed into 2 groups： Group A （90 patients） was examined using hysteroscopy and directed biopsy, and Group B （197 patients） was examined using fractional dilatation and curettage （D＆C）. The diagnostic veracity of the two methods, the rate of positive peritoneal cytology and the prognosis of the 2 groups were *** In Group A, 97.8% （88/90） of patients were diagnosed pathologically before surgery; the rate was 88.8% （175/197） for Group B. The difference between the 2 groups was statistically significant （P ＜0.05）. The sensitivity,specificity, positive predictive value and negative predictive value for the two methods for detecting cervical involvement were 77.8%, 100%, 100% and 97.6% for Group Aand 65.3%, 92.6%, 74.4% and 90.0% for Group B, respectively. The positive peritoneal cytology rate was 5.6% （5/90） in Group A and 6.09% （12/197） in Group B. The difference was not statistically significant （P ＞0.05）. The 3-year and 5-year overall survival rates were 91.4% （33/36） and 82.4% （14/17） for Group A and 95.6% （87/91） and 86.7% （39/45） for Group B. There were no statistically significant differences between the two groups＇ survival rates （P ＞0.05）.Conclusion Compared with fractional D＆C, hysteroscopy and directed biopsy offered improved pathological diagnostic accuracy before surgery and discovered cervical involvement more precisely in endometrial carcinoma patients, but it did not increase the positive peritoneal cytology rate or affect the prognosis of these patients.

关键词： hysteroscopy endometrial carcinoma dilatation and curettage diagnosis prognosis

Two novel ETFDH mutations in a patient with lipid storage myopathy

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Chinese Medical Journal 2019年第15期132卷 1876-1878页

作者： hong-liang xu Ya-Jun Lian Xin Chen Lu Zhang xuan Cheng Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China

The patient was a 17-year-old female who complained of episodic vomiting,exercise intolerance,and muscle *** symptoms started at 13 years and the initial symptom was vomiting after a *** the beginning,muscle fatigue and exercise intolerance after intense exercise only affected her lower *** symptoms progressed slowly in the past 4 *** upper limbs,as well as neck muscles were involved *** patient had no complaint about muscle stiffness,myalgia,or *** examination indicated that she had no obviously muscle *** muscle strength was 4 to 5 (Medical Research Council Scale) in proximal lower limbs,4/5 in proximal upper limbs,and almost normal in distal *** tendon reflexes were diminished and sensory examination was *** abnormality was evident in the serum blood,except for mild elevated creatinine kinase level (312 IU/L,normal 26-192 IU/L) and slightly increased lactate dehydrogenase level (112IU/L,normal 8-46IU/L).Echocardiography examinations showed the four cardiac chambers were normal in size and *** strength improved after treatment with riboflavin.

关键词： lipid storage myopathy ETFDH mutations

Classification of breast microcalcifications: radiological-pathological correlation

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中华医学杂志(英文版) 2005年第17期 23-29页

作者： SUN Zhe,liang hong-wei and xu Hui-mianDepartment of Oncological Surgery, First Affiliated Hospital of China Medical University, Shenyang 110001, China

Background Microcalcifications play a very important role in detection of breast cancer, especially early stagebreast ***, ambiguity still exists in understanding the relationship between radiological andpathological characteristics of *** definitive indication of a biopsy has not been *** purpose of this study is to evaluate the relationship of classification of breast microcalcifications using full-field digital mammography to the pathological *** For all the women an open biopsy had been *** hundred and three mammographsshowing clustered microcalcifications from 98 consecutive patients were reviewed along with their *** investigate the value of each criterion for the detection of cancer, univariate and multivariate analyseswere performed on the entire sample and then on morphological *** Pathological examination showed 67 malignant lesions (65.05%) and 36 benign lesions (34.95%).In the univariate analysis, four radiological variables were significant: morphological type (P=0.001),complicated by a mass (P=0.002), number of microcalcifications per cluster (P=0.02) and linear ortriangular distribution of clusters (P=0.009).In the multivariate analysis, two criteria remained significant:morphological type (P<0.001) and complicated by a mass (P=0.001).The percentage of malignancy was37.0%, 60.0%, 78.8%, and 88.9%, respectively, for type 2 (regularly punctiform), type 3 (dusty), type4 ( irregularly punctiform) and type 5 ( vermicular) microcalcifications ( Le Gal’s classification).Themalignancy was78.6% for microcalcifications complicated by a mass and 48.9% without a *** differencewas significant (P<0.05).The relationship between morphological types of microcalcifications and thepathological characteristics was also *** subgroups, type 3 (dusty) microcalcifications complicated by amass (P=0.001) or with the number of microcalcifications more than 10 (P

关键词： calcinosis · breast neoplasms · mammography

Effects of Grain Protein Content Selection on Protein Content and Key Enzyme Activity Involved in Nitrogen Metabolism in Progenies Derived from a Rice Cross

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Rice science 2010年第2期17卷 156-160页

作者： HUANG Xing JIN Zheng-xun LI Xiao-guang LIU hong-liang xu Mei-lan ZHANG Feng-zhuan ZHANG Zhong-chen Agricultural College Northeast Agricultural University Harbin 150030 China

Two japonica rice parents （Tong 769 and Xixuan 1） and their progenies, significantly different in protein content of grains, were investigated to reveal the activities of proteinase in leaves and glutamine synthetase in grains, as well as the dynamic changes of soluble protein content in grains during rice grain filling. The results showed that the parents were very similar in protein content, however, advanced lines with different protein contents in grains and varied activities of proteinase and glutamine synthetase were acquired by consecutively directional selection of the grain protein content in their progenies. Moreover, the enzyme activity and the protein content in grains exceeded their parents during grain filling. The protein content in grains was positively related with the proteinase activity, and the soluble protein content was negatively related with the glutamine synthetase activity in grains to some extent.

关键词： rice hybrid progeny protein content nitrogen metabolism enzyme activity

The NICS Values Scan in Three-dimensional Space of[8]cyclacene

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The NICS Values Scan in Three-dimensional Space of[8]cyclace...

Superhydrophobic and corrosion-resistant siloxane-modified MgAl-LDHs coatings on magnesium alloy prepared under mild conditions

第十三届全国量子化学会议

作者： Qing Li hong-liang xu Zhong-Min Su Institute of Functional Material Chemistry Faculty of ChemistryNortheast Normal University Department of Chemistry Faculty of ScienceYanbian University

Usually, the NICS values of 1.0 above the center that serves as the NICS probe to estimate the aromaticity of planar or nearly planar π-conjucted molecules. How to judge the aromaticity of hoop-shaped π-conjucted molecules?In present work, the[8]cyclacene as the representative molecule to explore the aromaticity of the[n]cyclacenes by the NICS values scan in three-dimensional space. As a result, the position and NICS values of maximum aromaticity on the different scan cross-section P（L=0～3.2） has been changed with the increase of distance L, in which L is defined as scan cross-section moving up distance from center cross-section P（L=0）. Among these NICS values, the maximum aromaticity was settled in dc-c=0.8 on the plane P（L=0.6） for hoop-shaped π-conjucted [8]cyclacene. We hope that present qualitatively analysis on the NICS values scan in three-dimensional space of[8]cyclacene can provide a new research perspective for the aromaticity of hoopshaped π-conjucted molecules.

关键词： [n]cyclacenes NICS scan the three-dimensional space

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 450-463页

作者： Wenxi Zhang Zhangzelong Zhuo Dan xu liang Wu Zhihui Xie Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province College of Chemistry and Chemical EngineeringChina West Normal UniversityNanchong 637002China College of Materials Science and Engineering/National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China

We have developed a superhydrophobic and corrosion-resistant LDH-W/PFDTMS composite coating on the surface of Mg *** composite comprised a tungstate-intercalated(LDH-W)underlayer that was grown at low temperature(relative to hydrothermal reaction conditions)under atmospheric pressure and an outer polysiloxane layer created from a solution containing perfluorodecyltrimethoxysilane(PFDTMS)using a simple immersion *** successful intercalation of tungstate into the LDH phase and the following formation of the polysiloxane layer were confirmed through X-ray diffraction(XRD),Fourier transform infrared(FTIR)spectroscopy,and X-ray photoelectron spectroscopy(XPS).The corrosion resistance of the LDH-W film,both before and after the PFDTMS modification,was evaluated using electrochemical impedance spectroscopy(EIS),Tafel curves,and immersion *** results showed that Mg coated with LDH-W/PFDTMS exhibited significantly enhanced corrosion protection compared to the unmodified LDHW film,with no apparent signs of corrosion after exposure to 3.5wt%NaCl solution for 15 ***,the LDH-W/PFDTMS coating demonstrated superior superhydrophobicity and self-cleaning properties against water and several common beverages,as confirmed by static contact angle and water-repellency *** results offer valuable insights into preparing superhydrophobic and corrosion-resistant LDH-based composite coatings on Mg alloy surfaces under relatively mild reaction conditions.

关键词： Mg alloy corrosion coating layered double hydroxide

The Solvation Effect of Photochromic Nonliner Optical Properties Switch

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The Solvation Effect of Photochromic Nonliner Optical Proper...