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Numerical study on the wave pattern characteristic of air layer in cavity and the effects of multiple influence factors

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Journal of Hydrodynamics 2023年第5期35卷 923-941页

作者： Xiao-song Zhang Xue-qin Ji Lei-qiang Chen Li-jin Gao hong-bo huang Fang-wen hong CSSC Shanghai Marine Energy Saving Technology Co.Ltd. Shanghai200011China China Ship Scientific Research Center Shanghai Branch Shanghai200011China China Ship Scientific Research Center Wuxi214082China School of Naval Architecture Ocean and Civil EngineeringState Key Laboratory of Ocean EngineeringShanghai Jiao Tong UniversityShanghai200240China

Air-layer drag reduction (ALDR) technology for ship energy saving is getting more and more attention in recent years because of the outstanding drag reduction effect. In order to promote practical application, it is necessary to fully understand the two phase flow characteristics of the air layer. Recent experimental studies have shown that the surface of the air layer presents wave pattern, which has an important influence on its damage risk. However, it is difficult to measure the wave pattern quantificationally due to the interference of equipment. The main goal of the present paper is to investigate the wave pattern characteristic of air layer in cavity using numerical simulation method. On this basis, the effect of flow and geometric influence factors are discussed to understand the key control conditions. A computational fluid dynamics (CFD) numerical method based on Reynolds averaged Navier-Stokes (RANS) equations and volume of fluid (VOF) interface capturing method is established, and has been successfully applied in the simulation of air layer wave pattern. both 2-D and 3-D simulations are carried out, aiming at analyzing air-water interface flow and vortex flow directly. Based on the simulation results, several important conclusions about the mechanism of air layer wave pattern can be obtained. Firstly, it is found to be an inherent characteristic that the wave height of the upstream air layer is higher than that of the downstream. The extremely high wave peak is easy to contact with the flat plate, leading to the breakup of air layer and a “central blank area” phenomenon. With the help of flow analysis, it is found that this characteristic is mainly caused by the strong counterclockwise vortex behind the bow wedge block. Secondly, the air layer stability is reduced with the increase of water flow velocity by affecting the wave height. There is a saturation point of air flow rate to reach maximum thickness of air layer. Thirdly, cavity configuration has ob

关键词： Air layer drag reduction wave pattern of air-water interface numerical simulation multiple influence factors vortex flow fields

Serum neuron-specific enolase:A promising biomarker of silicosis

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World Journal of Clinical Cases 2021年第5期9卷 1016-1025页

作者： hong-bo huang Jun-Ling huang Xiao-Ting Xu Kun-bo huang Yi-Jian Lin Jie-Bin Lin Xi-Bin Zhuang Department of Pulmonary and Critical Care Medicine Quanzhou First Hospital Affiliated to Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Clinical Laboratory Quanzhou First Hospital Affiliated to Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Internal Medicine Infectious Disease Hospital of QuanzhouQuanzhou 362000Fujian ProvinceChina

BACKGROUND Silicosis is a type of chronic pulmonary fibrosis caused by long-term inhalation of silica dust *** has been no ideal biomarker for the diagnosis and differential diagnosis of silicosis until *** have found that elevated neuron-specific enolase(NSE)concentration in the serum of silicosis patients is helpful for diagnosis and severity assessment of the ***,the number of cases in these studies was not enough to arouse *** To investigate the clinical significance of serum NSE in the diagnosis and staging of *** From January 2017 to June 2019,326 cases of silicosis confirmed in Quanzhou First Hospital Affiliated to Fujian Medical University were included in the silicosis group.A total of 328 healthy individuals or medical patients without silicosis were included in the control *** NSE concentrations of all subjects were determined by electrochemical *** There were no significant differences in sex,age,smoking index and complications between the silicosis and control *** mean serum NSE concentration was 26.57±20.95 ng/mL in the silicosis group and 12.42±2.68 ng/mL in the control *** difference between the two groups was significant(U=15187,P=0.000).Among the 326 patients with silicosis,103 had stage I silicosis,and the mean serum NSE concentration was 15.55±6.23 ng/*** mean serum NSE concentration was 21.85±12.05 ng/mL in 70 patients with stage II *** mean serum NSE concentration was 36.14±25.72 ng/mL in 153 patients with stage III ***-Wallis H test suggested that the difference in serum NSE concentration in silicosis patients in the three groups was significant(H=130.196,P=0.000).Receiver operating characteristic curve analysis indicated that the area under the curve was 0.858(95%confidence interval:0.828-0.888;P=0.000).When the NSE concentration was 15.82 ng/mL,the Jorden index was the largest,the sensitivity was 72%,and the specificity wa

关键词： Silicosis Neuron-specific enolase Receiver operating characteristic curve Disease stage Biomarker Diagnosis

Research and Review on Computer Forensics

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China Communications 2010年第6期7卷 37-43页

作者： Guo hong Jin bo huang Daoli Key Laboratory of Information Network Security Ministry of Public Security People＇s Republic of China （The 3rd Research Institute of Ministry of Public Security） Shanghai 201204 P. R. China

With the development of Internet and information technology, the digital crimes are also on the rise. Computer forensics is an emerging research area that applies computer investigation and analysis techniques to help detection of these crimes and gathering of digital evidence suitable for presentation in courts. This paper provides foundational concept of computer forensics, outlines various principles of computer forensics, discusses the model of computer forensics and presents a proposed model.

关键词： computer forensics computer crime digital evidence

25G和27G玻璃体切除术联合空气填充治疗RRD的疗效比较

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国际眼科杂志 2019年第9期19卷 1602-1604页

作者：黄红波韩光杰中国广西壮族自治区柳州市红十字会医院眼科

目的:对比25G和27G玻璃体切割术(PPV)联合无菌空气填充治疗孔源性视网膜脱离(RRD)的临床疗效和安全性。方法:回顾性分析2016-05/2018-06在我院行PPV联合空气填充治疗的RRD患者63例63眼,其中25G组33例33眼,27G组30例30眼。对比分析两组... 详细信息

目的:对比25G和27G玻璃体切割术(PPV)联合无菌空气填充治疗孔源性视网膜脱离(RRD)的临床疗效和安全性。方法:回顾性分析2016-05/2018-06在我院行PPV联合空气填充治疗的RRD患者63例63眼,其中25G组33例33眼,27G组30例30眼。对比分析两组术前和术后BCVA(LogMAR)、眼压、手术时间、视网膜复位率及并发症发生情况。结果:两组术前的基线资料均无差异(P>0.05)。25G组与27G组末次随访的BCVA均较术前改善(均P0.05)。25G组和27G组的平均手术时间分别为44.13±5.9、46.07±6.1min(t=0.028,P=0.412)。25G和27G组视网膜复位率分别为91%、93%(χ^2=0.015,P=0.902)。25G和27G组术后发生一过性低眼压(<6mmHg)的分别为5眼(15%)和3眼(10%)(χ^2=0.376,P=0.540)。两组均未观察到脉络膜脱离、感染性眼内炎等严重并发症。结论:27G PPV联合空气填充治疗RRD在手术时间、视网膜复位率、视力改善及并发症方面与25G无差异,是治疗RRD安全、经济而有效的手术方式。

关键词： 25G 27G 玻璃体切除术孔源性视网膜脱离无菌空气填充视网膜复位率

The potential mechanism and clinical application value of remote ischemic conditioning in stroke

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Neural Regeneration Research 2025年第6期20卷 1613-1627页

作者： Yajun Zhu Xiaoguo Li Xingwei Lei Liuyang Tang Daochen Wen bo Zeng Xiaofeng Zhang Zichao huang Zongduo Guo The First Affiliated Hospital of Chongqing Medical University ChongqingChina

Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation, cellular immunity, apoptosis, and autophagy, the exact underlying molecular mechanisms are unclear. This review summarizes the current status of different types of remote ischemic conditioning methods in animal and clinical studies and analyzes their commonalities and differences in neuroprotective mechanisms and signaling pathways. Remote ischemic conditioning has emerged as a potential therapeutic approach for improving stroke-induced brain injury owing to its simplicity, non-invasiveness, safety, and patient tolerability. Different forms of remote ischemic conditioning exhibit distinct intervention patterns, timing, and application range. Mechanistically, remote ischemic conditioning can exert neuroprotective effects by activating the Notch1/phosphatidylinositol 3-kinase/Akt signaling pathway, improving cerebral perfusion, suppressing neuroinflammation, inhibiting cell apoptosis, activating autophagy, and promoting neural regeneration. While remote ischemic conditioning has shown potential in improving stroke outcomes, its full clinical translation has not yet been achieved.

关键词： Akt apoptosis autophagy cerebral perfusion cerebral vascular stenosis clinical transformation hemorrhagic stroke ischemic stroke neuroinflammation neuroprotection Notch1 PI3K remote ischemic conditioning stroke

Application of the improved dung beetle optimizer,muti-head attention and hybrid deep learning algorithms to groundwater depth prediction in the Ningxia area,China

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 18-23页

作者： Jiarui Cai bo Sun Huijun Wang Yi Zheng Siyu Zhou Huixin Li Yanyan huang Peishu Zong Collaborative Innovation Center on forecast and Evaluation of Meteorological Disasters/Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment ChangeNanjing University of Information Science and TechnologyNanjingChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiChina China Meteorological Administration Key Laboratory of Transportation MeteorologyNanjingChina Jiangsu Meteorological Observatory NanjingChina

Due to the lack of accurate data and complex parameterization,the prediction of groundwater depth is a chal-lenge for numerical *** learning can effectively solve this issue and has been proven useful in the prediction of groundwater depth in many *** this study,two new models are applied to the prediction of groundwater depth in the Ningxia area,*** two models combine the improved dung beetle optimizer(Dbo)algorithm with two deep learning models:The Multi-head Attention-Convolution Neural Network-Long Short Term Memory networks(MH-CNN-LSTM)and the Multi-head Attention-Convolution Neural Network-Gated Recurrent Unit(MH-CNN-GRU).The models with Dbo show better prediction performance,with larger R(correlation coefficient),RPD(residual prediction deviation),and lower RMSE(root-mean-square error).Com-pared with the models with the original Dbo,the R and RPD of models with the improved Dbo increase by over 1.5%,and the RMSE decreases by over 1.8%,indicating better prediction *** addition,compared with the multiple linear regression model,a traditional statistical model,deep learning models have better prediction performance.

关键词： Groundwater depth Multi-head attention Improved dung beetle optimizer CNN-LSTM CNN-GRU Ningxia

基于遗传算法的旅客列车垃圾投放站布局优化研究

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铁道学报 2004年第1期26卷 120-123页

作者：郑凯汝宜红黄波北京交通大学经济管理学院北京100044

现阶段铁路路网干线上的旅客列车垃圾投放站基本是根据客运站的等级确定的。主管部门一直寻求旅客列车垃圾投放站布局的优化方案 ,以便重点建设永久型、现代化的处理设施 ,提高垃圾治理效果。文章运用遗传算法 ,建立路网干线旅客列车垃... 详细信息

现阶段铁路路网干线上的旅客列车垃圾投放站基本是根据客运站的等级确定的。主管部门一直寻求旅客列车垃圾投放站布局的优化方案 ,以便重点建设永久型、现代化的处理设施 ,提高垃圾治理效果。文章运用遗传算法 ,建立路网干线旅客列车垃圾投放站布局模型。

关键词：旅客列车垃圾遗传算法布局优化

Activation of β3-adrenergic receptor inhibits arrhythmia in the failing heart by modulating calcium handling

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Activation of β3-adrenergic receptor inhibits arrhythmia in...

Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment

第十三次全国心血管病学术会议

作者： LI Hai-tao,L1U Yu,huang He,TANG Ynag-hong, YANG bo,huang Cong-xin *Hainan Provincal People’s Hospital,Hainan 570311,China

Objective It is well known that activation of beta-ARs(beta adrenergic receptors)has been associated with occurrence of fatal ventricular tachycardia(VT)in chronic heart failure(CHF).Interestingly,endogenousβ3-AR up-regulate and elicit opposite effects in the failing myocardium that are largely unknown in ***,we investigate whetherβ3AR could effect on triggering of VT in *** In vivo studies were performed on arrhythmogenie rabbits produced by combined aortic insufficiency and aortic ***,ICI 118 551,BRL 37 344 and zinterol were administrated.

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Structural Durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-Jun Zhang Wen-Wei Wang Jing-Shui Zhen bo-Cheng Li De-Cheng Cai Yang-Yang Du Hui huang Offshore Oil Engineering Co.Ltd. Tianjin300461China Department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.

关键词： Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model