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Characterization of the Purified Glutathione S-transferases from Two Psocids Liposcelis bostrychophila and ***

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Agricultural Sciences in China 2010年第7期9卷 1008-1016页

作者： DOU Wei XIAO Li-sha NIU jin-zhi JIANG hong-bo WANG jin-jun Key Laboratory of Entomology and Pest Control Engineering College of Plant Protection Southwest University Chongqing 400716 P.R. China

Glutathione S-transferases（GSTs） from Liposcelis bostrychophila Badonnel and ***（Enderlein）（Psocoptera：Liposcelididae） were purified by glutathione-agarose affinity chromatography,and characterized subsequently by their Michaelis-Menten kinetics toward the artificial substrates 1-chloro-2,4-dinitrobenzene（CDNB） and reduced glutathione（GSH）,*** specific activity of the purified GST toward CDNB was 2.3-fold higher in *** than in *** the specific activities of purified enzymes varied between the two species,the purification yields were ***-PAGE revealed one band at 23 kDa for both the *** of *** exhibited higher Michaelis-Menten constants（Km） but lower maximal velocity（Vmax） values than those of *** optimum pH for CDNB conjugation of *** and *** GSTs was 7.0 and 7.5,and optimum temperature was 35 and 40°C,*** kinetics showed that cibacron blue,curcumin,bromosulfalein,ethacrynic acid,and carbosulfan had excellent inhibitory effects on GSTs in both species,but the inhibitory effects of beta-cypermethrin,fenpropathrin,tetraethylthiuram disulfide,and diethyl maleate were not significant.

关键词： GSTs purification psocids xenobiotic compounds

Tetrahedron constellation of gravitational wave observatory

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Science China(Physics,Mechanics & Astronomy) 2024年

作者： hong-bo jin Cong-Feng Qiao National Astronomical Observatories Chinese Academy of Sciences International Centre for Theoretical Physics Asia-Pacific University of Chinese Academy of Sciences School of Physical Sciences University of Chinese Academy of Sciences

For the first time,we have introduced the tetrahedron constellation of gravitational wave observatory (TEGO) composed of four identical spacecrafts (S/Cs).The laser telescopes and their pointing structures are mounted on the S/C platform and are evenly distributed at three locations 120 degrees *** structures form automatically a stable mass center for the *** time delay interferometry (TDI) is used to suppress the frequency noise of gravitational wave (GW) *** unequal-arm Michelson TDI configuration and the Sagnac TDI configuration are equally effective at eliminating the laser frequency noise based on the TEGO ***,compared with the configurations of LISA,Taiji,and TianQin,the TEGO has more combinations of optical paths in its TDI system sensitive to GW *** six arms of TEGO are simultaneously sensitive to the six polarization modes of *** sensitivity implies that GW modes beyond the predictions of general relativity (GR)can be detected *** instance,a scalar longitudinal mode of GWs,which is not predicted by GR,has been identified as a dominant polarization *** mode is found to be evident in the response amplitudes of the TEGO arms,such as between S/C1 and S/C4,and S/C3 and S/C4,at certain orbital positions.

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Research and Review on Computer Forensics

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China Communications 2010年第6期7卷 37-43页

作者： Guo hong jin bo Huang Daoli Key Laboratory of Information Network Security Ministry of Public Security People＇s Republic of China （The 3rd Research Institute of Ministry of Public Security） Shanghai 201204 P. R. China

With the development of Internet and information technology, the digital crimes are also on the rise. Computer forensics is an emerging research area that applies computer investigation and analysis techniques to help detection of these crimes and gathering of digital evidence suitable for presentation in courts. This paper provides foundational concept of computer forensics, outlines various principles of computer forensics, discusses the model of computer forensics and presents a proposed model.

关键词： computer forensics computer crime digital evidence

Taiji data challenge for exploring gravitational wave universe

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Frontiers of physics 2023年第6期18卷 93-106页

作者： Zhixiang Ren Tianyu Zhao Zhoujian Cao Zong-Kuan Guo Wen-Biao Han hong-bo jin Yue-Liang Wu Taiji Laboratory for Gravitational Wave Universe University of Chinese Academy of Sciences(UCAS)Beijing 100049China Peng Cheng Laboratory Shenzhen 518055China Department of Astronomy Beijing Normal UniversityBeijing 100875China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUCASHangzhou 310024China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences UCASBeijing 100049China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China School of Astronomy and Space Science UCASBeijing 100049China International Centre for Theoretical Physics Asia-Pacific(ICTP-AP UNESCO)UCASBeijing 100190China Shanghai Frontiers Science Center for Gravitational Wave Detection Shanghai 200240China Key Laboratory of Computational Astrophysics National Astronomical ObservatoriesBeijing 100101China

The direct observation of gravitational waves(GWs)opens a new window for exploring new physics from quanta to cosmos and provides a new tool for probing the evolution of *** detection in space covers a broad spectrum ranging over more than four orders of magnitude and enables us to study rich physical and astronomical *** is a proposed space-based gravitational wave(GW)detection mission that will be launched in the *** will be exposed to numerous overlapping and persistent GW signals buried in the foreground and background,posing various data analysis *** order to empower potential scientific discoveries,the Mock Laser Interferometer Space Antenna(LISA)data challenge and the LISA data challenge(LDC)were *** LDC provides a baseline framework,the first LDC needs to be updated with more realistic simulations and adjusted detector responses for Taiji’s *** this paper,we review the scientific objectives and the roadmap for Taiji,as well as the technical difficulties in data analysis and the data generation strategy,and present the associated data *** contrast to LDC,we utilize second-order Keplerian orbit and second-generation time delay interferometry ***,we employ a new model for the extreme-mass-ratio inspiral waveform and stochastic GW background spectrum,which enables us to test general relativity and measure the non-Gaussianity of curvature ***,we present a comprehensive showcase of parameter estimation using a toy *** showcase not only demonstrates the scientific potential of the Taiji data challenge(TDC)but also serves to validate the effectiveness of the *** the first data challenge for Taiji,we aim to build an open ground for data analysis related to Taiji sources and *** details can be found on the official website(***).

关键词： gravitational wave universe evolution Taiji data challenge

Effects of hydrogen on a tungsten grain boundary:A first-principles computational tensile test

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Progress in Natural Science:Materials International 2011年第3期21卷 240-245页

作者： hong-bo ZHOU,Shuo jin,Ying ZHANG,Guang-hong LU Department of Physics,Key Laboratory of Micro-nano Measurement-Manipulation and Physics(Ministry of Education),Beijing University of Aeronautics and Astronautics,Beijing 100191,China Department of Physics Key Laboratory of Micro-nano Measurement-Manipulation and Physics (Ministry of Education) Beijing University of Aeronautics and Astronautics Beijing 100191 China

A first-principles computational tensile test has been preformed to investigate the effects of hydrogen on a tungsten grain *** has been found that the maximum ideal tensile strength of the tungsten grain boundary with hydrogen atom segregation was 32.85 GPa,which was about 9%lower than that of the clean tungsten grain boundary(36.23 GPa).This indicated that the theoretical strength of the tungsten grain boundary became weaker in the presence of the hydrogen *** configuration analysis showed that the grain boundary fracture was caused by the interfacial bond *** Griffith fracture energy was calculated to be 161 meV/A~2(2.58 J/m~2) and 155 meV/A~2(2.48 J/m~2) for the tungsten grain boundary without and with the hydrogen atom segregation,*** solution energy of the hydrogen atom in a fracture free surface was -0.31 eV,which was 0.08 eV lower than that of the hydrogen atom in a tungsten grain *** indicated that hydrogen was a grain boundary embrittler according to the Rice-Wang thermodynamic *** Bader charge analysis suggested that the physical origin for hydrogen-induced embrittlement was the charge transfer induced by hydrogen in the tungsten grain boundary.

关键词： tungsten hydrogen grain boundary tensile strength first-principles

Estimation of far-field wavefront error of tilt-to-length distortion coupling in space-based gravitational wave detection

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Chinese Physics B 2023年第2期32卷 20-26页

作者：陶雅正金洪波吴岳良 The School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China The International Centre for Theoretical Physics Asia-Pacific University of Chinese Academy of SciencesBeijing 100190China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Hangzhou Institute for Advanced Study University of Chinese Academy of SciencesHangzhou 310024China

In space-based gravitational wave detection, the estimation of far-field wavefront error of the distorted beam is the precondition for the noise reduction. Zernike polynomials are used to describe the wavefront error of the transmitted distorted beam. The propagation of a laser beam between two telescope apertures is calculated numerically. Far-field wavefront error is estimated with the absolute height of the peak-to-valley phase deviation between the distorted Gaussian beam and a reference distortion-free Gaussian beam. The results show that the pointing jitter is strongly related to the wavefront error. Furthermore, when the jitter decreases 10 times from 100 nrad to 10 nrad, the wavefront error reduces for more than an order of magnitude. In the analysis of multi-parameter minimization, the minimum of wavefront error tends to Z[5,3] Zernike in some parameter ranges. Some Zernikes have a strong correlation with the wavefront error of the received beam. When the aperture diameter increases at Z[5,3] Zernike, the wavefront error is not monotonic and has ***, the wavefront error almost remains constant with the arm length increasing from 10-1Mkm to 10~*** the arm length decreases for three orders of magnitude from 10-1Mkm to 10-4Mkm, the wavefront error has only an order of magnitude increasing. In the range of 10-4Mkm to 10~3Mkm, the lowest limit of the wavefront error is from 0.5 fm to 0.015 fm at Z[5,3] Zernike and 10 nrad jitter.

关键词： laser optical systems space mission gravitational wave

Isospin and Symmetry Structure in ^(36)Ar

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Communications in Theoretical Physics 2007年第12期48卷 1067-1071页

作者： BAI hong-bo ZHANG jin-Fu CAO Wan-Cang LLi-Jun Zhaorigt DONG hong-Fei Department of Physics,Chifeng University,Chifeng 024001,ChinaLI Yan-Song Department of Physics,Tsinghua University,Beijing 100084,China Department of Physics Chifeng University Chifeng 024001 China Department of Physics Tsinghua University Beijing 100084 China

The interacting boson model-3(IBM-3) has been used to study the isospin excitation states and electromag-netic transitions for ^(36)Ar *** mixed symmetry states and superdeformed band at low spin are also *** theoretical calculations are in agreement with experimental data,and the ^(36)Ar is superdeformed rotational nucleusclose to the SU(3) *** present calcula,tions indicate that the 2_4^+ state is the lowest mixed symmetry state and thelowest isospin T=1 excitation state and at about 6.2 MeV,and the bandhead of superdeformed band is 0_2^+ state.

关键词： IBM-3 energy level isospin mixed symmetry states electromagnetic transitions

FK506 contributes to peripheral nerve regeneration by inhibiting neuroinflammatory responses and promoting neuron survival

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Neural Regeneration Research 2025年第7期20卷 2108-2115页

作者： Yuhui Kou Zongxue jin Yusong Yuan bo Ma Wenyong Xie Na Han Department of Trauma and Orthopedics Peking University People’s HospitalBeijingChina National Center for Trauma Medicine Peking University People’s HospitalBeijingChina Key Laboratory of Trauma and Neural Regeneration(Peking University) Ministry of EducationBeijingChina Trauma Medicine Center Peking University People’s HospitalBeijingChina Department of Orthopedics China-Japan Friendship HospitalBeijingChina

FK506(Tacrolimus)is a systemic immunosuppressant approved by the *** and Drug ***506 has been shown to promote peripheral nerve regeneration,however,its precise mechanism of action and its pathways remain *** this study,we established a rat model of sciatic nerve injury and found that FK506 improved the morphology of the injured sciatic nerve,increased the numbers of motor and sensory neurons,reduced inflammatory responses,markedly improved the conduction function of the injured nerve,and promoted motor function *** findings suggest that FK506 promotes peripheral nerve structure recovery and functional regeneration by reducing the intensity of inflammation after neuronal injury and increasing the number of surviving neurons.

关键词： FK506 inflammation motor neurons nerve regeneration neuron peripheral nerve injury sensory neurons

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海南胡椒药材的HPLC指纹图谱研究

中草药 2007年第7期38卷 1084-1087页

作者：张艳秋洪金波海南省药物研究所海南海口570314

目的建立胡椒药材的指纹图谱,为胡椒的质量控制提供新方法。方法采用高效液相色谱法,选用YMCC18色谱柱(250mm×4.6mm,5μm),流动相为甲醇-水(65∶35);体积流量为1mL/min;检测波长为245nm。结果建立了胡椒药材的指纹图谱,并检测了不同来... 详细信息

目的建立胡椒药材的指纹图谱,为胡椒的质量控制提供新方法。方法采用高效液相色谱法,选用YMCC18色谱柱(250mm×4.6mm,5μm),流动相为甲醇-水(65∶35);体积流量为1mL/min;检测波长为245nm。结果建立了胡椒药材的指纹图谱,并检测了不同来源10批胡椒药材HPLC指纹图谱,相似度较高,并且利用"中药色谱指纹图谱相似度评价软件"生成了胡椒药材的对照指纹图谱,共有指纹峰12个,各色谱峰分离良好;对比分析4批市售胡椒粉HPLC指纹图谱与对照图谱的相似度。结论所建立的胡椒药材的指纹图谱有良好的精密度、重现性、稳定性,适于胡椒的质量控制。

关键词：胡椒 HPLC 指纹图谱相似度