检索结果-南通市图书馆

Serum vaspin level in relation to postprandial plasma glucose concentration in subjects with diabetes

Chinese Medical Journal 2009年第21期122卷 2530-2533页

作者： YE Yin HOU Xu-hong PAN Xiao-ping lu Jun-xi JIA Wei-ping Department of Endocrinology and Metabolism Shanghai Clinical Center for Diabetes Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Diabetes Institute Shanghai Key Laboratory of Diabetes Mellitus Shanghai 200233 China

Background Vaspin is a newly-identified adipocytokine related to obesity and insulin sensitivity. However, its pathophysiologic role in humans remains largely unknown. The aim of our study was to investigate the relationship between serum vaspin level and glucose metabolism or obesity in Chinese adults. Methods A total of 123 subjects, including 84 subjects with normal glucose tolerance （NGT） and 39 subjects with diabetes, were enrolled in this study. Anthropometric parameters, abdominal fat areas, plasma glucose concentration, serum insulin, lipids, and vaspin level were measured in each participant. Results Serum vaspin concentration was significantly higher in diabetic patients than that in NGT subjects （592 （438-695） pg/ml vs 380 （294-517） pg/ml, P=0.020） in women. In all participants, age, fasting plasma glucose concentration （FPG）, 2-hour post-load plasma glucose （PG2h）, hemoglobin Alc （HbAlc） and high-density lipoprotein cholesterol （HDL-c） significantly increased from the lower tertile to the higher tertile of vaspin. Univariate linear regression analyses revealed that vaspin level was only positively correlated with age （β=0.340, P=0.002） in NGT subjects. And vaspin was positively associated with FPG （β=0.365, P=0.023）, PG2h （β=0.526, P=0.001）, HbAlc （β=0.388, P=0.016）, and HDL-c （β=0.353, P=0.027）, while negatively with homeostasis model assessment of beta cell function （HOMA-β）（β=-0.361, P=-0.024） in diabetic patients. In stepwise multivariate regression analyses, age was independently associated with circulating vaspin in NGT subjects, whereas PG2h was an independent predictor of vaspin in diabetic patients. In addition, there was no significant difference of serum vaspin level between men and women. And no significant correlations between vaspin and body fat indexes were detected. Conclusions Serum vaspin level is higher in diabetic patients than that in NGT subjects in women. Age predicts serum vaspin level in NGT subjects, while PG2h is independently

关键词： vaspin protein, human blood glucose diabetes mellitus obesity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dynamic effects of high-pressure pulsed water jet in low-permeability coal seams

引用

Journal of Coal Science & Engineering(China) 2009年第3期15卷 284-288页

作者： LI Xiao-hong ZHOU Dong-ping lu Yi-yu KANG Yong ZHAO Yu WANG Xiao-chuan Key Lab for the Exploitation of Southwestern Resources ＆ Environmental Disaster Control Engineering Chongqing University Chongqing 400030 China

Mine gas extraction in China is difficult due to the characteristics such as micro-porosity,low-permeability and high adsorption of coal *** pulsed mechanismof a high-pressure pulsed water jet was studied through theoretical analysis,experimentand field *** results show that high-pressure pulsed water jet has threedynamic ***'s more,the three dynamic effects can be found in low-permeabilitycoal seams.A new pulsed water jet with 200-1 000 Hz oscillation frequency andpeak pressure 2.5 times than average pressure was *** bubble collapsing,sound vibration and instantaneous high pressures over 100 MPa enhanced the cuttingability of the high-pressure *** high-pressure pulsed water jet drilling and slotting,the exposure area of coal bodies was greatly enlarged and pressure of the coal seamsrapidly ***,the permeability of coal seams was improved and gas absorptionrate also *** results show that gas adsorption rate decreasedby 30%-40%and the penetrability coefficient increased 100 *** proves that high-pressurepulsed water is more efficient than other conventional methods.

关键词： high-pressure pulsed water jet gas desorption penetrability dynamic effects

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Calcitriol attenuates liver fibrosis through hepatitis C virus nonstructural protein 3-transactivated protein 1-mediated TGF β1/Smad3 and NF-κB signaling pathways

引用

World Journal of Gastroenterology 2023年第18期29卷 2798-2817页

作者： Liu Shi Li Zhou Ming Han Yu Zhang Yang Zhang Xiao-Xue Yuan hong-ping lu Yun Wang Xue-Liang Yang Chen Liu Jun Wang Pu Liang Shun-Ai Liu Xiao-Jing Liu Jun Cheng Shu-Mei Lin Department of Infectious Disease Medicine The First Hospital Affiliated to Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina China-Japan Friendship Hospital Department of Infectious Disease China-Japan Friendship HospitalBeijing 100029China Institute of Infectious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China The Division of Liver Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Institute of Liver Diseases Beijing Pan-Asia Tongze Institute of Biomedicine Co.LtdBeijing 100015China Department of Rehabilitation Medicine The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Beijing Key Laboratory of Emerging Infectious Diseases Peking University Ditan Teaching HospitalBeijing 100015China

BACKGROUND Hepatic fibrosis is a serious condition,and the development of hepatic fibrosis can lead to a series of ***,the pathogenesis of hepatic fibrosis remains unclear,and effective therapy options are still *** group identified hepatitis C virus nonstructural protein 3-transactivated protein 1(NS3TP1) by suppressive subtractive hybridization and bioinformatics analysis,but its role in diseases including hepatic fibrosis remains ***,additional studies on the function of NS3TP1 in hepatic fibrosis are urgently needed to provide new targets for *** To elucidate the mechanism of NS3TP1 in hepatic fibrosis and the regulatory effects of calcitriol on *** Twenty-four male C57BL/6 mice were randomized and separated into three groups,comprising the normal,fibrosis,and calcitriol treatment groups,and liver fibrosis was modeled by carbon tetrachloride(CCl4).To evaluate the level of hepatic fibrosis in every group,serological and pathological examinations of the liver were ***-β1 was administered to boost the in vitro cultivation of LX-2 ***3TP1,α-smooth muscle actin(α-SMA),collagen I,and collagen Ⅲ in every group were examined using a Western blot and real-time quantitative polymerase chain *** activity of the transforming growth factor beta 1(TGFβ1)/Smad3 and NF-κB signaling pathways in each group of cells transfected with pcDNA-NS3TP1 or siRNA-NS3TP1 was *** statistical analysis of the data was performed using the Student’s t *** NS3TP1 promoted the activation,proliferation,and differentiation of hepatic stellate cells(HSCs)and enhanced hepatic fibrosis via the TGFβ1/Smad3 and NF-κB signaling pathways,as evidenced by the presence of α-SMA,collagen I,collagen Ⅲ,p-smad3,and p-p65 in LX-2 cells,which were upregulated after NS3TP1 overexpression and downregulated after NS3TP1 *** proliferation of HSCs was lowered after NS3TP1 interference and elevated after

关键词： Nonstructural protein 3-transactivated protein 1 Calcitriol Liver fibrosis Hepatic stellate cells Mouse model TGFβ1/Smad3 NF-κB Signaling pathway

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于“生活教育”理念的中学作文教学实践

引用

浙江海洋学院学报（人文科学版） 2010年第2期27卷 133-135页

作者：洪路平杭二中树兰实验学校浙江杭州311100

按照杜威"教育即生活""从做中学"的理论,针对当前高中作文教学领域日益明显的技术主义浮躁风气,提出作文教学应与生活教育相结合的实践策略,引导学生体验生活、深入思考,抒写真情实感,使写作呈现本色状态,并形成自主写作的动机。

关键词：杜威陶行知生活教育中学作文教学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Autophagy Vitalizes Appressorium Morphogenesis in Magnaporthe oryzae

Autophagy Vitalizes Appressorium Morphogenesis in Magnaporth...

引用

中国植物病理学会2008年学术年会

作者： Xiao-hong Liu Jian-ping lu Tong-Bao Liu Fu-Cheng Lin Biotechnology Institute, Zhejiang University, Hangzhou 310029,P. R. China

One of the most widespread and devastating plant diseases is rice blast which causes significant crop losses throughout China,South East Asia,and South America,representing a loss of 157 million tons of rice per annum...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Understanding the local structure and thermophysical behavior of Mg-La liquid alloys via machine learning potential

引用

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 439-449页

作者： Jia Zhao Taixi Feng Guimin lu National Engineering Research Center for Integrated Utilization of Salt Lake Resource East China University of Science and TechnologyShanghai 200237China Joint International Laboratory for Potassium and Lithium Strategic Resources East China University of Science and TechnologyShanghai 200237China

The local structure and thermophysical behavior of Mg-La liquid alloys were in-depth understood using deep potential molecular dynamic(DPMD) simulation driven via machine learning to promote the development of Mg-La alloys. The robustness of the trained deep potential(DP) model was thoroughly evaluated through several aspects, including root-mean-square errors(RMSEs), energy and force data, and structural information comparison results;the results indicate the carefully trained DP model is reliable. The component and temperature dependence of the local structure in the Mg-La liquid alloy was analyzed. The effect of Mg content in the system on the first coordination shell of the atomic pairs is the same as that of temperature. The pre-peak demonstrated in the structure factor indicates the presence of a medium-range ordered structure in the Mg-La liquid alloy, which is particularly pronounced in the 80at% Mg system and disappears at elevated temperatures. The density, self-diffusion coefficient, and shear viscosity for the Mg-La liquid alloy were predicted via DPMD simulation, the evolution patterns with Mg content and temperature were subsequently discussed, and a database was established accordingly. Finally, the mixing enthalpy and elemental activity of the Mg-La liquid alloy at 1200 K were reliably evaluated,which provides new guidance for related studies.

关键词： magnesium-lanthanum liquid alloys local structure macroscopic properties thermodynamic behavior deep potential mo-lecular dynamic simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

LiDAR-Visual SLAM with Integrated Semantic and Texture Information for Enhanced Ecological Monitoring Vehicle Localization

引用

Computers, Materials & Continua 2025年第1期82卷 1401-1416页

作者： Yiqing lu Liutao Zhao Qiankun Zhao Foreign Environmental Cooperation Center Ministry of Ecology and Environment of PRCBeijing100035China Beijing Computing Center Co. Ltd.Beijing Academy of Science and TechnologyBeijing100083China Beijing Guyu Interactive Artificial Intelligence Application Co. Ltd.Beijing100024China

Ecological monitoring vehicles are equipped with a range of sensors and monitoring devices designed to gather data on ecological and environmental *** vehicles are crucial in various fields,including environmental science research,ecological and environmental monitoring projects,disaster response,and emergency management.A key method employed in these vehicles for achieving high-precision positioning is LiDAR(lightlaser detection and ranging)-Visual Simultaneous Localization and Mapping(SLAM).However,maintaining highprecision localization in complex scenarios,such as degraded environments or when dynamic objects are present,remains a significant *** address this issue,we integrate both semantic and texture information from LiDAR and cameras to enhance the robustness and efficiency of data ***,semantic information simplifies the modeling of scene elements,reducing the reliance on dense point clouds,which can be less ***,visual texture information complements LiDAR-Visual localization by providing additional contextual *** incorporating semantic and texture details frompaired images and point clouds,we significantly improve the quality of data association,thereby increasing the success rate of *** approach not only enhances the operational capabilities of ecological monitoring vehicles in complex environments but also contributes to improving the overall efficiency and effectiveness of ecological monitoring and environmental protection efforts.

关键词： LiDAR-Visual simultaneous localization and mapping integrated semantic texture information

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A quantum-search-based multi-classifier for image recognition

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 21-31页

作者： lu Liu Xingyu Wu lufan Zhang Chuan Wang School of Artificial Intelligence Beijing Normal University Applied Optics Beijing Area Major Laboratory Beijing Normal University

The multi-class classification of images is a pivotal challenge within the realm of image processing. As the volume of visual data continues to expand, there is a burgeoning interest in harnessing the unique capabilities of quantum computation to augment the efficiency of classification tasks. However, many existing methods for training quantum image multi-classifiers parallel classical machine learning techniques, where the requisite circuit measurements increase linearly with the volume of training data. This work introduces a novel approach for training a quantum image multi-classifier based on the quantum search algorithm. We have meticulously conducted rigorous experiments on a handwritten digit dataset, a classic benchmark in the field. The results have been meticulously compared with previous works, and the comparative analysis not only validates the efficiency of our proposed approach, requiring only O(N/b) measurements during training, but also highlights a significant quadratic speedup of the algorithm.

关键词： quantum computation image recognition quantum search algorithm

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Orbitronics for energy-efficient magnetization switching

引用

Science China(Information Sciences) 2025年第1期68卷 398-399页

作者： Yuxuan YAO Daoqian ZHU Qingtao XIA Jianing LIANG Yuhao JIANG Zhiyang PENG Jiaxu LI Chen XIAO Renyou XU Wenwen WANG Xiantao SHANG Shiyang lu Dapeng ZHU hong-Xi LIU Kaihua CAO Weisheng ZHAO Fert Beijing Institute School of Integrated Circuit Science and Engineering Beihang University National Key Lab of Spintronics Institute of International Innovation Beihang University Qingdao Research Institute Beihang University Truth Memory Corporation

Spin-orbit torque （SOT）,as a promising writing method for magnetic random-access memory （MRAM）,has garnered widespread interest for over a decade [1].Heavy metals,such as β-W,have been broadly adopted as spin current sources,but suffer from phase change at a limited thickness,resulting in a dramatic reduction of the charge-tospin conversion efficiency θSH[2].The thickness limitation leads to stringent etching conditions and large distribution among devices,posing challenges for simultaneously satisfying SOT efficiency,etching-stop margins,and back-end-ofline （BEOL） compatibility.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unraveling the origins of PGY-sRNA-6,BZL-sRNA-20,and XKC-sRNA-h3

引用

Science China Life Sciences 2025年

作者： Shanfa lu State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Institute of Medicinal Plant DevelopmentChinese Academy of Medical Sciences&Peking Union Medical College Engineering Research Center of Chinese Medicine Resource Ministry of Education

Dear Editor,The regulatory role of herbal sRNAs in humans and animals is an interesting research ***,current evidence is insufficient to conclude that herbal sRNAs are novel precision medicines.I previously showed that HJT-sRNA-m1-HJT-sRNA-m8,identified as herbal sRNAs previously (Du et al.,2019),may be derived from humans and/or animals(lu,2023).To minimize errors during herbal sRNA analysis,I provided a list of matters needing special attention and proposed problem-solving solutions for researchers working on sRNA cross-kingdom regulation (lu,2023).

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：