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Journal of Systems Science and Information 2019年第3期10卷 257-269页

作者： Wei ZHANG Tao WU hong ma Guixin LI Department of Electronic and Optical Engineering Space Engineering University

In space information networks, satellites are generally in high speed orbit motion. In order to obtain better spacial and temporal coverage performance, satellites should cooperate with each other as a constellation. Previous works on constellations mainly focus on global seamless coverage using fewer satellites. However, like most countries, it is hard for China to build ground stations in overseas, and the geostationary Earth orbit position resource is scarce. In this paper, we investigate the constellation design problem with restricted ground supporting. We first proposes a 'backbone network + enhanced network' hybrid constellation design approach. Then a hybrid '4GEO+5IGSO' constellation is designed using the proposed approach, and the coverage performance of this constellation is analyzed in detail. Simulation results show the proposed approach can realize global seamless coverage only using a small number of satellites. Furthermore, the proposed hybrid constellation meets the coverage demand only relies on ground stations inside China.

关键词： space information network constellation design hybrid constellation GEO satellite IGSO satellite

Soil Respiration and Litter Decomposition Increased Following Perennial Forb Invasion into an Annual Grassland

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Pedosphere 2016年第4期26卷 567-576页

作者： ZHANG Ling ma Xiaochi WANG hong LIU Shuwei Evan SIEmaNN ZOU Jianwen College of Forestry Jiangxi Agricultural University College of Resources and Environmental Sciences Nanjing Agricultural University Department of Ecology and Evolutionary Biology Rice University

Exotic plant invasions may alter ecosystem carbon processes, especially when native plants are displaced by plants of a different functional group. Forb invasions into grasslands are common, yet little is known about how they impact carbon cycling. We conducted a field study over 2 years from April 2010 to march 2012 in China to examine changes in soil respiration （Rsoil） following invasion of exotic perennial forb species （Alternanthera philoxeroides or Solidago canadensis） into an annual grassland dominated by a native annual graminoid （Eragrostis pilosa）. Measurements of Rsoil were taken once a week in stands of the native annual graminoid or one of the forb species using static chamber-gas chromatograph method. Aboveground litterfall of each of the three focal species was collected biweekly and litter decomposition rates were measured in a 6-month litterbag experiment. The monthly average and annual cumulative Rsoil increased following invasion by either forb species. The increases in cumulative Rsoil were smaller with invasion of Solidago （36%） than Alternanthera （65%）. Both invasive forbs were associated with higher litter quantity and quality （e.g., C：N ratio） than the native annum graminoid. Compared to the native annual graminoid, the invasive forbs Altevnanthera （155%） and Solidago （361%） produced larger amounts of more rapidly decomposing litter, with the litter decay constant k being 3.8, 2.0 and 1.0 for Alternanthera, Solidago and Eragrostis, respectively. Functional groups of the invasive plants and the native plants they replaced appear to be useful predictors of directions of changes in Rsoil, but the magnitude of changes in Rsoil seems to be sensitive to variations in invader functional traits.

关键词： carbon cycling exotic plant functional group functional traits invasive plants litterfall native plants

Serum level changes of inflammatory cytokines in patients with moderate to severe acne vulgaris treated with dual-wavelength laser

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Chinese Journal of Plastic and Reconstructive Surgery 2023年第2期5卷 47-52页

作者： Yang Liu Qilin Sun Hui Xu gang ma Pinru Wu Department of Dermatology Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China Department of Laser and Aesthetic Medicine Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China

Background:Acne vulgaris(AV)is a common inflammatory skin *** various mechanisms have been indicated in the etiopathogenesis of AV,the exact pathophysiology remains *** lasers have been used to treat AV;however,the serum level changes of inflammatory cytokines after laser therapy have not been *** aimed to investigate the relationship between inflammatory changes and remission on the opposite side in patients with moderate to severe AV after treating half of the face with 595-and 1064-nm dualwavelength ***:In total,18 patients(9 male and 9 female)between 16 and 35 years of age with moderate to severe AV were evaluated in the *** severity was classified according to the Pillsbury grading system of *** were randomized to receive a series of two treatment sessions at intervals of 2 weeks and followed up at 2 weeks after the final treatment.A 3 mL blood sample was drawn from every subject each time,and serum levels of inflammatory cytokines such as interleukin(IL)-6,IL-8,and IL-22 were determined using enzyme-linked immunosorbent assay at baseline and 2 weeks after each *** was determined by a blinded assessment of photographs taken before and after the final ***:Inflammation was significantly reduced on both the treated and untreated sides,and symptoms of AV lesions were *** patients showed a significant increase in serum IL-22 levels after the first laser therapy,with no significant difference in serum IL-6 and IL-8 *** the second laser therapy,serum IL-6,IL-8,and IL-22 levels were significantly *** significant side effects such as bruising,edema,hyperpigmentation,hypopigmentation,or scarring were ***:Half-face treatment with 595-and 1064-nm dual-wavelength laser for moderate and severe AV showed a significant effect of full-face remission,which was associated with a gradual decrease in IL-6,IL-8,and IL-22 levels after half-fac

关键词： Acne vulgaris Dual-wavelength laser Inflammatory cytokines Serum

Selection of Observation Position and Orientation in Visual Servoing with Eye-in-vehicle Configuration for manipulator

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International Journal of Automation and computing 2019年第6期16卷 761-774页

作者： hong-Xuan ma Wei Zou Zheng Zhu Chi Zhang Zhao-Bing Kang Institute of Automation Chinese Academy of Science

In this paper, we propose a method to select the observation position in visual servoing with an eye-in-vehicle configuration for the manipulator. In traditional visual servoing, the images taken by the camera may have various problems, including being out of view, large perspective aberrance, improper projection area of object in images and so on. In this paper, we propose a method to determine the observation position to solve these problems. A mobile robot system with pan-tilt camera is designed, which calculates the observation position based on an observation and then moves there. Both simulation and experimental results are provided to validate the effectiveness of the proposed method.

关键词： Eye-in-vehicle observation position mobile robot visual servoing pan-tilt camera platform

An insoluble polysaccharide from the sclerotium of Poria cocos improves hyperglycemia, hyperlipidemia and hepatic steatosis in ob/ob mice via modulation of gut microbiota

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Chinese Journal of Natural Medicines 2019年第1期17卷 3-14页

作者： SUN Shan-Shan WANG Kai ma Ke BAO Li LIU hong-Wei School of Life Sciences University of Science and Technology of China State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of Sciences University of Chinese Academy of Sciences

Metabolic syndrome characterized by obesity, hyperglycemia and liver steatosis is becoming prevalent all over the world. Herein, a water insoluble polysaccharide(WIP) was isolated and identified from the sclerotium of Poria cocos, a widely used Traditional Chinese Medicine. WIP was confirmed to be a(1-3)-β-D-glucan with an average Mw of 4.486 × 10~6 Da by NMR and SEC-RI-maLLS analyses. Furthermore, oral treatment with WIP from P. cocos significantly improved glucose and lipid metabolism and alleviated hepatic steatosis in ob/ob mice. 16 S DNA sequencing analysis of cecum content from WIP-treated mice indicated the increase of butyrate-producing bacteria Lachnospiracea, Clostridium. It was also observed that WIP treatment elevated the level of butyrate in gut, improved the gut mucosal integrity and activated the intestinal PPAR-γ pathway. Fecal transplantation experiments definitely confirmed the causative role of gut microbiota in mediating the benefits of WIP. It is the first report that the water insoluble polysaccharide from the sclerotium of P. cocos modulates gut microbiota to improve hyperglycemia and hyperlipidemia. Thereby, WIP from P. cocos, as a prebiotic, has the potential for the prevention or cure of metabolic diseases and may elucidate new mechanism for the efficacies of this traditional herbal medicine on the regulation of lipid and glucose metabolism.

关键词： Poria cocos Water insoluble polysaccharide Metabolic syndrome Prebiotics Gut microbiota

前两阶原子交换能之比对bcc二元合金微结构的影响

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材料研究学报 2000年第5期14卷 463-468页

作者：马钢中国科学技术大学力学和机械工程系合肥市230027

利用Ｍｏｎｔｅ　Ｃａｒｌｏ法计算ｂｃｃ二元合金在低温下的微观结构，计算中原子交换能满足ｅ１＜０和ｅ２＜０．对于合金Ａ－５０Ｂ；ｅ２／ｅ１＜２／３和ｅ２／ｅ１＞２／３的情形分别对应完整的Ｂ２和Ｂ３２结构而对于合金... 详细信息

利用Ｍｏｎｔｅ　Ｃａｒｌｏ法计算ｂｃｃ二元合金在低温下的微观结构，计算中原子交换能满足ｅ１＜０和ｅ２＜０．对于合金Ａ－５０Ｂ；ｅ２／ｅ１＜２／３和ｅ２／ｅ１＞２／３的情形分别对应完整的Ｂ２和Ｂ３２结构而对于合金Ａ－２５Ｂ，ｅ２／ｅ１＜０．６时，用ＭｏｎｔｅＣａｒｌｏ方法不易得到完整的ＤＯ３结构，且Ｂ２有序化过程早于

关键词： Monte Carlo方法原子交换能 bcc二元合金结构

医患共同决策对老年慢性病共病患者家庭医生签约服务质量的影响

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中国卫生政策研究 2024年第8期17卷 1-9页

作者：熊巨洋朱璇马赫华中科技大学同济医学院医药卫生管理学院湖北武汉430030

目的:深入剖析医患共同决策水平对老年慢性病共病患者家庭医生签约服务质量的作用路径,为推动慢性病健康管理、改善患者就医体验感和签约服务质量提供参考。方法:在武汉市和贵阳市采取多阶段随机抽样方法对599名老年慢性病共病患者及其... 详细信息

目的:深入剖析医患共同决策水平对老年慢性病共病患者家庭医生签约服务质量的作用路径,为推动慢性病健康管理、改善患者就医体验感和签约服务质量提供参考。方法:在武汉市和贵阳市采取多阶段随机抽样方法对599名老年慢性病共病患者及其对应的63名签约医生开展问卷调查,借助分层回归模型分析医患共同决策水平对签约服务质量的作用路径。结果:我国中西部地区老年慢性病共病患者的医患共同决策得分为32.07±6.46,家庭医生签约服务质量得分为95.20±8.73,其中经济性和纵向连续性维度得分较低。分层回归模型分析结果显示医患共同决策水平对签约服务质量产生正向影响(β=0.369,P<0.05),家庭医生对签约患者的信任程度起到正向调节作用(β=0.548,P<0.05)。结论:我国中西部地区老年慢性病共病患者的医患共同决策水平和家庭医生签约服务质量均处于中等水平且有待提升,医患共同决策显著提升签约服务质量,对签约患者的信任程度强化共同决策对服务质量的正向效应。今后应加强医患共同决策、规范慢性病患者转诊服务、强化医患沟通信任,切实提升家庭医生签约服务质量。

关键词：医患共同决策慢性病共病家庭医生签约服务服务质量

乳腺MRI图像特征与保乳手术可行性的相关性分析

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磁共振成像 2024年第1期15卷 43-47,60页

作者：刘梁生刘佩芳马文娟张宇李艳博王嘉慧路红天津医科大学肿瘤医院乳腺影像诊断科国家恶性肿瘤临床医学研究中心天津市肿瘤防治重点实验室天津市恶性肿瘤临床医学研究中心乳腺癌防治教育部重点实验室天津300060

目的探讨乳腺癌保乳手术(breast conserving surgery, BCS)成功及失败相关的术前MRI影像特征和临床病理特征,为BCS可行性分析提供影像学依据。材料与方法回顾性分析2018年3月至2021年5月行BCS且术前行MRI检查的患者资料,并根据是否最... 详细信息

目的探讨乳腺癌保乳手术(breast conserving surgery, BCS)成功及失败相关的术前MRI影像特征和临床病理特征,为BCS可行性分析提供影像学依据。材料与方法回顾性分析2018年3月至2021年5月行BCS且术前行MRI检查的患者资料,并根据是否最终改行全乳切除术的手术结果分为失败组和成功组。收集的影像特征包括:病灶大小、左右侧、是否肿块、深度、纤维腺体组织量、是否对称、相关征象、背景实质强化(background parenchymal enhancement, BPE)、时间强度曲线、T1信号以及T2信号。临床病理特征包括:患者年龄、人表皮生长因子受体2 (human epidermal growth factor receptor 2, HER-2)、雌激素受体(estrogen receptor, ER)、孕激素受体(progesterone receptor, PR)状态及增殖指数Ki-67水平、分子分型以及是否导管内癌。采用单因素及多因素logistic回归对两组间的影像特征及临床病理特征进行分析,以P<0.05为差异具有统计学意义。结果 BCS失败和成功组的样本量分别为47例和91例。单因素及多因素logistic回归分析显示BPE在两组间差异有统计学意义。使用BPE极少强化作为参考,它与BPE轻度强化之间差异没有统计学意义[优势比(odds ratio, OR)=0.317,95%置信区间(confidence interval, CI):0.374~6.552,P=0.654]。它与中度强化之间差异具有统计学意义(OR=1.674,95%CI:1.392~26.420,P=0.022)和BPE重度增强(OR=1.569,95%CI:1.128~25.809,P=0.044)。然而,其他临床病理和影像学特征在BCS成功组与失败组间差异无统计学意义。结论 BPE与BCS成功与否具有一定相关性,更高的BPE程度提示更大的BCS失败可能性,BPE可能作为术前MRI评估乳腺癌BCS可行性分析的有效指标,有助于医生制订准确的手术策略。

关键词：癌症乳腺癌保乳手术影像特征磁共振成像

Advancements of macrophages Involvement in Pathological Progression of Colitis-Associated Colorectal Cancer and Associated Pharmacological Interventions

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Chinese Journal of Integrative Medicine 2024年第6期30卷 565-576页

作者： KE Jun-yu SONG Jin-bin LI Long HE Zhen-fan HUANG Zhuo-jian LIU Zheng-lin CHEN Gui-rong WANG Hai-yan WEN Su-ru ZHOU Heng-li ma Hui-lin DU Qun WU Yong-qiang LI Yan-wu CHEN Xin-lin School of Basic Medical Sciences Guangzhou University of Chinese MedicineGuangzhou510006China Department of Surgery II Gaozhou Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese MedicineGaozhou525200China Science and Technology Innovation Center Guangzhou University of Chinese MedicineGuangzhou510405China The First Clinical Medical College of Guangzhou University of Traditional Chinese Medicine Guangzhou510405China

Intestinal macrophages play crucial roles in both intestinal inflammation and immune homeostasis. They can adopt two distinct phenotypes, primarily determined by environmental cues. These phenotypes encompass the classically activated pro-inflammatory M1 phenotype, as well as the alternatively activated anti-inflammatory M2 phenotype. In regular conditions, intestinal macrophages serve to shield the gut from inflammatory harm. However, when a combination of genetic and environmental elements influences the polarization of these macrophages, it can result in an M1/M2 macrophage activation imbalance, subsequently leading to a loss of control over intestinal inflammation. This shift transforms normal inflammatory responses into pathological damage within the intestines. In patients with ulcerative colitis-associated colorectal cancer (UC-CRC), disorders related to intestinal inflammation are closely correlated with an imbalance in the polarization of intestinal M1/M2 macrophages. Therefore, reinstating the equilibrium in M1/M2 macrophage polarization could potentially serve as an effective approach to the prevention and treatment of UC-CRC. This paper aims to scrutinize the clinical evidence regarding Chinese medicine (CM) in the treatment of UC-CRC, the pivotal role of macrophage polarization in UC-CRC pathogenesis, and the potential mechanisms through which CM regulates macrophage polarization to address UC-CRC. Our objective is to offer fresh perspectives for clinical application, fundamental research, and pharmaceutical advancement in UC-CRC.

关键词： macrophage ulcerative colitis colon cancer Chinese medicine

UV-B has larger negative impacts on invasive populations of Triadica sebifera but ozone impacts do not vary

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Journal of Plant Ecology 2016年第1期9卷 61-68页

作者： hong Wang Xiaochi ma Ling Zhang Evan Siemann Jianwen Zou College of Resources and Environmental Sciences Nanjing Agricultural UniversityNanjing 210095China Department of Biosciences Rice UniversityHoustonTX 77005USA College of Forestry Jiangxi Agricultural UniversityNanchang 330045China

Aims Abiotic stresses may interact with each other to determine impacts on plants so that their combined impact is less than or more than *** UV-B radiation and surface ozone(O3)are two major components of global change that may have such interactive ***,invasive and native populations of plants may respond differently to stresses as they can vary in primary and secondary *** Here,we conducted a factorial field experiment with open-top chambers assigned to an ozone treatment(ambient,100 ppb,or 150 ppb)and UV-B treatment(ambient or increased 20%).We grew seedlings of native and invasive populations of Triadica sebifera in these chambers for one growing *** Findings Invasive plants grew faster than native plants in ambient UV-B but they did not differ significantly in elevated *** production of invasive plants was especially sensitive to UV-B in a way that increased with UV-B for native plants but decreased for invasive plants which may be important for nutrient *** ambient UV-B,total mass decreased as ozone *** mass was lower with elevated UV-B but there was no additional impact of increasing *** area did not decrease with UV-B so SLA and LAR were lowest at ambient ozone *** results suggest that the effects of ozone will depend on UV-B conditions perhaps due to changes in foliar *** traits that allow invasive populations of plants to be successful invaders may make them especially sensitive to UV-B which may reduce their success in future climatic conditions.

关键词： invasive UV-B O3 cross-tolerance litter