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Rare Metals 2020年第8期39卷 928-935页

作者： Xing-Pin Chen Dan Chen hong-fu sun Li-Xia Wang Du Shang College of Materials Science and Engineering Chongqing UniversityChongqing 400044China

The evolution of microstructure and texture at four strain levels was investigated in Ni-5 at%W alloy by means of electron backscatter diffraction(EBSD)*** deformation microstructure evolves gradually from microbands(MBs)to typical lamellar structures with strain increasing in cold-rolled materials,while only lamellar structures in heavily cold-rolled ***,quantitative analysis of microstructure and texture was *** indicates that the texture is a typical pure metal deformation texture,but a few cube and rolling direction(RD)-rotated cube orientations also can be observed in the deformed *** use of high-temperature annealing enables an area fraction of cube orientation>95%to be obtained for high strained *** addition,it is worth noting that the point-to-point misorientation inside the band with various orientations is found to keep quite *** the point-to-origin misorientation over the same distance is dependent on strain and orientation type in the *** cube-oriented regions were characterized by a high accumulated orientation gradient,close to 28°,compared to the non-cube-oriented *** means that the accumulated orientation gradient only occurs in the cube band with the reduction of 98%,which partly explains the formation of strong cube texture after high-temperature annealing.

关键词： Cold rolling Microstructure Texture Orientation relationship

二维波动方程速度的正则化-同伦-测井约束反演

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地球物理学报 2005年第6期48卷 1441-1448页

作者：傅红笋韩波哈尔滨工业大学数学系哈尔滨150001

针对二维波动方程反问题,将大范围收敛的同伦方法引入速度参数的反演过程中,并将其与求解不适定问题的Tikhonov正则化有机结合,提出了一种新的、特别适用于非线性的、不适定的、多极值的地震勘探反演问题的反演策略:正则化-同伦方法.为... 详细信息

针对二维波动方程反问题,将大范围收敛的同伦方法引入速度参数的反演过程中,并将其与求解不适定问题的Tikhonov正则化有机结合,提出了一种新的、特别适用于非线性的、不适定的、多极值的地震勘探反演问题的反演策略:正则化-同伦方法.为了充分利用测井资料和地震资料的互补特征,进一步提高反演分辨率并压制噪声,设计了正则化-同伦-测井约束联合反演方法.大量数值试验结果表明了这两种方法的有效性.

关键词：二维波动方程速度反演 Tikhonov正则化同伦方法测井约束

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测井约束地震波形反演的同伦摄动法

地球物理学报 2012年第9期55卷 3173-3179页

作者：傅红笋曹莉韩波大连海事大学数学系大连116026 哈尔滨工业大学数学系哈尔滨150001

测井数据和地震数据是地震勘探中两种最重要的资料.测井约束地震波形反演是在非线性波形反演的基础上,利用已知测井资料详细的垂直分辨能力和地震资料均匀密集的水平采样特点,通过迭代反演来求取一个具有较高分辨率的速度参数.本文建立... 详细信息

测井数据和地震数据是地震勘探中两种最重要的资料.测井约束地震波形反演是在非线性波形反演的基础上,利用已知测井资料详细的垂直分辨能力和地震资料均匀密集的水平采样特点,通过迭代反演来求取一个具有较高分辨率的速度参数.本文建立了测井约束反演模型,研究了测井约束下地震波形反演的同伦摄动求解方法.同伦摄动法作为一种新的、求解数学物理中各种非线性问题的有效方法,具有计算速度快、计算精度高的优点.这对于提高反演的精度和效率是十分有益的.为了表征该方法的有效性和稳定性,分别对水平层状介质模型和逆冲断层带模型进行了数值模拟,并与Landweber迭代法相对比,结果表明该算法具有更好的收敛性,能够取得更为满意的反演效果.

关键词：测井资料约束速度反演同伦摄动法 Landweber方法

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动力系统法求解逆热传导

大连海事大学学报 2009年第3期35卷 111-114页

作者：傅红笋韩波大连海事大学数学系辽宁大连116026 哈尔滨工业大学数学系哈尔滨150001

为克服逆热传导的严重不适定性,基于动力系统法的一种简单形式,并利用后验停止准则来获取其稳定的数值解.理论分析和数值试验结果均表明:该方法具有简洁、高效、结果稳定等优点.

关键词：动力系统法逆热传导不适定性

正则化-同伦方法用于电阻抗断层成像(英文)

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黑龙江大学自然科学学报 2011年第3期28卷 319-323页

作者：傅红笋韩波大连海事大学数学系大连116026 哈尔滨工业大学数学系哈尔滨150001

电阻抗断层成像问题本质上是一个非线性、不适定反问题,必须进行正则化处理。基于Tik-honov正则化方法,结合大范围收敛的同伦方法,设计Tikhonov正则化-同伦方法,旨在克服传统重构算法(如Newton类算法等)的局部收敛性,解决初值难以有效... 详细信息

电阻抗断层成像问题本质上是一个非线性、不适定反问题,必须进行正则化处理。基于Tik-honov正则化方法,结合大范围收敛的同伦方法,设计Tikhonov正则化-同伦方法,旨在克服传统重构算法(如Newton类算法等)的局部收敛性,解决初值难以有效选取的难题。针对电阻抗断层成像的图像重建仿真试验,结果表明该方法的有效性与全局收敛性。

关键词：电阻抗断层成像 Tikhonov正则化同伦方法

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-Yan sun Lingyun Nie Jing Zhang Xue Fang hongmei Luo Chuanhai fu Zhiyi Wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

A bio-inspired optical imaging method for robotic perception in turbid water

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Science China Technological Sciences 2025年第1期 79-81页

作者： Xudong sun Yafeng LI Peng LIN Xiaodi SHANG Xianping fu School of Information Science and Technology Dalian Maritime University College of Computer Science and Technology Qingdao University

In the realm of underwater robotics, optical imaging plays a pivotal role in many scientific researches. Due to the effects of absorption and scattering,images captured in turbid water are severely degraded. Therefore, enhancing the quality of underwater optical images stands paramount in ensuring the continued advancement and efficacy of underwater robots across its multifarious applications.

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荒漠生境下柠条幼苗存活与生长对水分添加和沙埋的响应

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生态学杂志 2018年第5期37卷 1382-1390页

作者：罗永红闫兴富孙毅张金峰国家民委生态系统模型及应用重点实验室北方民族大学生物科学与工程学院银川750021

为了解柠条幼苗生长与存活对荒漠生境下沙埋和水分添加的响应,在宁夏灵武白芨滩国家级自然保护区南部荒漠灌丛群落,通过水分添加和持续沙埋处理,研究了柠条幼苗的存活与生长对水分添加和沙埋的响应。结果表明:水分添加有利于柠条幼苗的... 详细信息

为了解柠条幼苗生长与存活对荒漠生境下沙埋和水分添加的响应,在宁夏灵武白芨滩国家级自然保护区南部荒漠灌丛群落,通过水分添加和持续沙埋处理,研究了柠条幼苗的存活与生长对水分添加和沙埋的响应。结果表明:水分添加有利于柠条幼苗的存活与生长,幼苗最终留存率显著提高(P<0.05),且幼苗株高、单株叶面积和总干质量显著增大(P<0.05),侧根数、小叶数、相对生长率和净同化率也均有不同程度增大。沙埋抑制柠条幼苗的存活与生长,试验结束时,沙埋幼苗在水分添加条件下的最终留存率显著低于无沙埋幼苗(P<0.05);除株高外,沙埋幼苗的基径、小叶数、单株叶面积、总干质量、相对生长率等均显著减小(P<0.05),主根长、侧根数和净同化率也不同程度减小。沙埋幼苗的比叶面积、比根长和比枝长均显著大于无沙埋幼苗(P<0.05),但前者的根冠比显著小于后者(P<0.05);沙埋幼苗的比根长在水分添加条件下显著减小(P<0.05),但不论是否沙埋,幼苗根冠比、比叶面积和比枝长在有无水分添加间均差异不显著。

关键词：柠条水分添加持续沙埋幼苗存活幼苗生长形态学可塑性

Single-cell omics: experimental workflow, data analyses and applications

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Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying sun Haoyan Li Dongqing sun Shaliu fu Lei Gu Xin Shao Qinqin Wang Xin Dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei Wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

THREE NEW fuROCOUMARINS FROM NOTOPTERYGIUM INCISUM TING

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Chinese Chemical Letters 1994年第7期5卷 593-596页

作者： Yong Qing XIAO Xiao hong LIU, and You fu sun(Institute of Chinese Materia Medica, Academy of Traditional Chinese Medicine,beijing 1O0700)Kimiye BASA. Masahiko TANIGUCHI and Mitsugi KOZAWA(Osaka University of Pharmaceutical Sciences. Osaka 58O Japan)

From the EtOAc extract of the underground part of notopterygium incisum Ting.,three new furocoumarins. 5-[(2E)-3,7-dimethyl-5-ethylox-2.,6-octadienyloxylpsoralen named ethylnotopterol(A),5-(2E,5E)-3,7-dimethyl-7-dimet...

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