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Discrete vortices on anisotropic lattices

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Frontiers of physics 2015年第4期10卷 55-60页

作者： Gui-Hua chen hong-cheng wang Zi-Fa chen Department of Electronic Engineering Dongguan University of Technology Dongguan 523808 China

We consider the effects of anisotropy on two types of localized states with topological charges equal to 1 in two-dimensional nonlinear lattices, nsing the discrete nonlinear SchrSdinger equation as a paradigm model. We find that on-site-centered vortices with different propagation constants are not globally stable, and that upper and lower boundaries of the propagation constant exist. The region between these two boundaries is the domain outside of which the on-site-centered vortices are unstable. This region decreases in size as the anisotropy parameter is gradually increased. We also consider off-site-centered vortices on anisotropic lattices, which are unstable on this lattice type and either transform into stable quadrupoles or collapse. We find that the transformation of off-site- centered vortices into quadrupoles, which occurs on anisotropic lattices, cannot occur on isotropic lattices. In the quadrupole case, a propagation-constant region also exists, outside of which the localized states cannot stably exist. The influence of anisotropy on this region is almost identical to its effects on the on-site-centered vortex case.

关键词： anisotropy discrete vortex quadrupole localized state

Cisplatin-loaded Polymer/Magnetite Composite Nanoparticles as Multifunctional Therapeutic Nanomedicine

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Chinese Journal of Polymer Science 2014年第10期32卷 1329-1337页

作者： Yan Zhang Xiao-ju wang Miao Guo 阎虎生 chen-hong wang 刘克良 Key Laboratory of Functional Polymer Materials (Ministry of Education) and Institute of Polymer Chemistry Nankai University and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Beijing Institute of Pharmacology and Toxicology

Multifunctional nanocarriers with multilayer core-shell architecture were prepared by coating superparamagnetic Fe3O4 nanoparticles with diblock copolymer folate-poly（ethylene glycol）-b-poly（glycerol monomethacrylate）（FA-PEG-b- PGMA）, and triblock copolymer methoxy poly（ethylene glycol）-b-poly（2-（dimethylamino） ethyl methacrylate）-b- poly（glycerol monomethacrylate）（MPEG-b-PDMA-b-PGMA）. The PGMA segment was attached to the surfaces of Fe304 nanoparticles, and the outer PEG shell imparted biocompatibility. In addition, folate was conjugated onto the surfaces of the nanocarriers. Cisplatin was then loaded into the nanocarrier by coordination between the Pt atom in cisplatin and the amine groups in the inner shell of the multilayer architecture. The loaded cisplatin showed pH-responsive release： slower release at pH 7.4 （i.e. mimicking the blood environment） and faster release at more acidic pH （i.e. mimicking endosome/lysosome conditions）. All of the cisplatin-loaded nanoparticles showed concentration-dependent cytotoxicity in HeLa cells. However, the folate-conjugated cisplatin-loaded carriers exhibited higher cytotoxicity in HeLa cells than non-folate conjugated cisplatin-loaded carriers.

关键词： Drug delivery Folate Targeting Cisplatin Magnetic.

Three new C_(20)-diterpenoid alkaloids from Delphinium anthriscifolium ***

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Chinese Chemical Letters 2009年第6期20卷 698-701页

作者： Xiao Yu Liu Qiao hong chen Feng Peng wang Department of Chemistry of Medicinal Natural Products West China College of Pharmacy Sichuan University Chengdu 610041 China

Three new C20-diterpenoid alkaloids, designated as anthriscifolmines A-C （1-3）, together with two known alkaloids denudatine and delgramine, were isolated from the whole herb of Delphinium anthriscifolium var. savat... 详细信息

关键词： Delphinium anthriscifolium vat. savatieri C20-diterpenoid alkaloid Anthriscifolmines A-C

Development and assessment of quantitative structure-activity relationship models for bioconcentration factors of organic pollutants

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Chinese Science Bulletin 2009年第4期54卷 628-634页

作者： QIN hong chen JingWen wang Ying wang Bin LI XueHua LI Fei wang YaNan Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education) Department of Environmental Scienceand Technology Dalian University of Technology Dalian 116024 China

Bioconcentration factors (BCFs) are of great importance for ecological risk assessment of organic chemicals. In this study, a quantitative structure-activity relationship (QSAR) model for fish BCFs of 8 groups of compounds was developed employing partial least squares (PLS) regression, based on linear solvation energy relationship (LSER) theory and theoretical molecular structural descriptors. The guidelines for development and validation of QSAR models proposed by the Organization for Economic Cooperation and Development (OECD) were followed. The model results show that the main factors governing logBCF are Connolly molecular area (CMA), average molecular polarizability (α) and molecular weight (MW). Thus molecular size plays a critical role in affecting the bioconcentration of organic pollutants in fish. For the established model, the multiple correlation coefficient square (RY2) = 0.868, the root mean square error (RMSE) = 0.553 log units, and the leave-many-out cross-validated Q2CUM = 0.860, indicating its good goodness-of-fit and robustness. The model predictivity was evaluated by external validation, with the external explained variance (QE2XT) = 0.755 and RMSE = 0.647 log units. Moreover, the applicability domain of the developed model was assessed and visualized by the Williams plot. The developed QSAR model can be used to predict fish logBCF for organic chemicals within the application domain.

关键词：生物浓缩因子定量结构活动关系有机污染物生态学风险评估

Dynamical properties of ultracold Bose atomic gases in one-dimensional optical lattices created by two schemes

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Chinese Physics B 2019年第9期28卷 175-179页

作者： Jiang Zhu cheng-Ling Bian hong-chen wang College of Physics and Electronic Engineering Hainan Normal University

An optical lattice could be produced either by splitting an input light(splitting scheme) or by reflecting the input light by a mirror(retro-reflected scheme).We study quantum dynamical properties of an atomic Bose-Einstein condensate(BEC) in the two *** a mean field theory and neglecting collision interactions between atoms, we find that the momentum and spatial distributions of BEC are always symmetric in the splitting scheme which, however, are asymmetric in the retro-reflected *** reason for this difference is due to the local field ***, we propose an effective method to avoid asymmetric diffraction.

关键词： optical lattice Bose-Einstein condensate local field effect

Simultaneous Determination of Gold and Platinum by Double Artificial Neural Network Analysis with Flow-injection Chemiluminescence

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Chinese Chemical Letters 2006年第10期17卷 1343-1346页

作者： Ming Yang LIU Hai Tao ZHANG Jun Feng LI Shu Gui chen hong Yan wang College of chemistry Jilin University Changchun 130012

A highly sensitive double artificial neural network （DANN） analysis with flow-injection chemiluminescence （FI-CL） has been developed to simultaneously determine the trace amounts of the gold and platinum in simula... 详细信息

关键词： Double artificial neural networks flow-injection chemiluminescence simultaneous determination gold and platinum.

Clinical features and therapeutic strategies of obstructive azoospermia in patients treated by bilateral inguinal hernia repair in childhood

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Asian Journal of Andrology 2014年第5期16卷 745-748,I0010页

作者： Xiang-Feng chen hong-Xiang wang Yi-Dong Liu Kai Sun Li-Xin Zhou Yi-Ran Huang Zheng Li Ping Ping Department of Urology Ren Ji Hospital School of Medicine Shanghai Jiao Tong University Shanghai Institute of Andrology Shanghai China

Childhood inguinal herniorrhaphy is one common cause of seminal tract obstruction. Vasovasostomy （VV） can reconstruct seminal deferens and result in appearance of sperm and natural pregnancy in some patients. Secondary epididymal obstruction caused by a relatively long-term vasal obstruction is a common cause of lower patency compared with VV due to vasectomy in adults. From July 2007 to June 2012, a total of 62 patients, with history of childhood inguinal herniorrhaphy and diagnosed as obstructive azoospermia were treated in our center. The overall patency rate and natural pregnancy rate were 56.5% （35/62） and 25.8% （16/62）, respectively. 48.4% （30/62） of the patients underwent bilateral VV in the inguinal region, with a patency rate of 76.7% （23/30） and a natural pregnancy rate of 36.7% （11/30）, respectively. 30.6% （19/62） of the patients underwent bilateral VV and unilateral or bilateral vasoepididymostomies due to ipsilateral epididymal obstruction with the patency and natural pregnancy rate decreasing to 63.2% （12/19） and 26.3% （5/19）. 21.0% （13/62） of the patients merely underwent vasal exploration without reconstruction due to failure to find distal vasal stump, etc. Our study indicate that microsurgical reanastomosis is an effective treatment for some patients with seminal tract obstruction caused by childhood inguinal herniorrhaphy.

关键词： azoospermia inguinal herniorrhaphy microsurgical reanastomosis

Diet-induced hyperhomocysteinemia exacerbates vascular reverse remodeling of balloon-injured arteries in rat

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Chinese Medical Journal 2008年第22期121卷 2265-2271页

作者： GUO Yan-hong chen Feng-ying wang Gui-song chen Li GAO Wei Department of Cardiology Peking University Third Hospital and Key Laboratory of Molecular Cardiovascular Science Ministry of Education Beijing 100191 China

Background While hyperhomocysteinemia is associated with an increased risk of cardiovascular diseases, the effect of hyperhomocysteinemia on the vascular adventitia and vessel remodeling has not been clearly demonstrated. We investigated the effect of the hyperhomocysteinemia on adventitial hyperplasia and vascular remodeling following balloon injury in rats and the underlying mechanisms. Methods Rats were fed with diet containing methionine for 4 weeks to increase plasma homocysteine before balloon injury. Vascular geometrical changes were assessed at different time points following balloon injury. The collagen deposition was determined by picrosirius red staining and immunohistochemical staining. Results When compared with normal diet group, moderate hyperhomocysteinemia in methionine diet group significantly exacerbated adventitial hyperplasia at day 7 and collagen deposition mainly in the adventitia at day 28 following balloon injury. The increased plasma homocysteine level significantly increased collagen deposition in the adventitia. There was a negative correlation （r=-0.698; P〈0.01） between the luminal area and the collagen content in the adventitia on day 28 following balloon injury. In cultured adventitial fibroblasts isolated from rat aorta, 100 pmol/L L-homocysteine （L-Hcy） significantly down-regulated matrix metalloproteinase-2 activity by 43% as determined by in vitro gelatin zymography （P 〈0.05） and up-regulated the expression of collagen type I by 187% （P 〈0.05） assessed by Western blotting. Conclusions Hyperhomocysteinemia exacerbated vascular constrictive remodeling by accelerated neointima formation and collagen accumulation in the adventitia. Increased collagen deposition may be the underlying mechanism.

关键词： homocysteine arteries adventitia collagen matrix metalloproteinase

ENHANCEMENT　OF　EXCIMER　FORMATION　AND　PHOTODIMERIZATIONON　OF　9－ANTHRYLMETHYL　DODECANOATE　VIA　AGGREGATION

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Chinese Chemical Letters 1994年第4期5卷 287-290页

作者： Xi LI Xiao hong DENG Xiao hong wang and chen Ho TUNG(The Laboratory of Photochemistry, Institute of PhotographicChemistry, Academia Sinica, Beijing 100101)

The diluted solution of 9-anthrylmethyl dodecanoate in aqueous organic binary mixed solvents exhibits strong excimer fluorescence. Photoirradiation of this solution results in the dimerization of the anthracene nucleus at 9, 10-positions to form almost exclusively the head-to-head (h-h) dimer. This is contrary to the photodimerization in organic solvents, where the major product is the head-to-tail (h-t) dimer.

关键词： VIA DODECANOATE ANTHRYLMETHYL AGGREGATION AND