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Growth of BaTiO_3-Ag hybrid composite films at room temperature by aerosol deposition

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中国有色金属学会会刊：英文版 2012年第S3期22卷 735-739页

作者： Young Joon YOON Sung Hwan CHO Jihoon KIM Hyo Tae KIM hong koo baik Jong-Hee KIM Nano-Convergence Intelligence Material Team Korea Institute of Ceramic Engineering and Technology Division of Advanced Materials Engineering Kongju National University Department of Materials Science and Engineering Yonsei University

Barium titanate (BaTiO3) and silver (Ag) composite film with high dielectric constant was grown at room temperature by an aerosol deposition *** dielectric constant increases by 0.5 times after adding Ag to the BaTiO3 matrix,compared with pure *** high dielectric constant can be attributed to the percolation effect of Ag inclusions in the BaTiO3 *** Ag was present in the form of discrete layer in the BaTiO3 *** dielectric properties of BaTiO3 Ag were discussed in detail taking into account the changes in microstructures.

关键词： composites percolation aerosol deposition BaTiO3 Ag

Callus proliferation-induced hypoxic microenvironment decreases shoot regeneration competence in Arabidopsis

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Molecular Plant 2024年第3期17卷 395-408页

作者： Dohee koo hong Gil Lee Soon Hyung Bae Kyounghee Lee Pil Joon Seo Department of Chemistry Seoul National UniversitySeoul 08826Korea Plant Genomics and Breeding Institute Seoul National UniversitySeoul 08826Korea Research Institute of Basic Sciences Seoul National UniversitySeoul 08826Korea

Plants are aerobic organisms that rely on molecular oxygen for respiratory energy *** conditions,with oxygen levels ranging between 1%and 5%,usually limit aerobic respiration and affect plant growth and ***,we demonstrate that the hypoxic microenvironment induced by active cell proliferation during the two-step plant regeneration process intrinsically represses the regener-ation competence of the callus in Arabidopsis *** showed that hypoxia-repressed plant regener-ation is mediated by the RELATED TO APETALA2.12(RAP2.12)protein,a memberof the Ethylene Response Factor VIl(ERF-Vll)*** found that the hypoxia-activated RAP2.12 protein promotes salicylic acid(SA)biosynthesis and defense responses,thereby inhibiting pluripotency acquisition and de novo shoot regeneration in *** and genetic analyses revealed that RAP2.12 could bind directly to the SALICYLIC ACID INDUCTION DEFICIENT 2(SID2)gene promoter and activate SA biosynthesis,repressing plant regeneration possibly via a PLETHORA(PLT)-dependent ***,the rap2.12 mutant calli exhibits enhanced shoot regeneration,which is impaired by SA *** together,these find-ings uncover that the cell proliferation-dependent hypoxic microenvironment reduces cellular pluripotency and plant regeneration through the RAP2.12-SID2 module.

关键词： callus cell proliferation-induced hypoxia SID2 plant regeneration salicylic acid RAP2.12

使用低压平行板等离子体对天然皮革进行表面改性

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北京皮革（中外皮革信息版）（中） 2007年第8期 95-98页

作者： Jai Hyuk Ohoi Eung Suok Lee hong koo baik Se-Jong Lee Ki Moon Soog Myung Keun Hwang Chang Su Huh 郝霞（译） Yonsei大学冶金工程系 134 Shinchon—dongSeodaemun—Ku首尔120—749韩国 Kyungsung大学材料科学与工程系 Busan 608—756韩国新材料科学与应用物理系 Konkuk大学Chungju 380—701韩国 Inha大学电气工程系 253 Yonghyun—dongInchon市402—751韩国不详

本文将低压平行板等离子体用于控制天然皮革的表面可湿性，提高其可染性，防水性和湿擦性能。经过等离子体处理后，由于等离子体的原子团和离子的轰击，使得天然皮革不均匀的表面趋于光滑。试验表明，亲水性随着表面处理时间的增加而增... 详细信息

本文将低压平行板等离子体用于控制天然皮革的表面可湿性，提高其可染性，防水性和湿擦性能。经过等离子体处理后，由于等离子体的原子团和离子的轰击，使得天然皮革不均匀的表面趋于光滑。试验表明，亲水性随着表面处理时间的增加而增强。CF4等离子体处理可以显著提高天然皮革的防水性能，且不使其脱色。等离子体处理后，湿擦性能可以提高大约2级（使用灰度色标）。由此，我们可以断言，重复进行等离子体处理，将会提高皮革的湿擦效果。

关键词：等离子体天然皮革表面处理

Recent developments in selective laser processes for wearable devices

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Bio-Design and Manufacturing 2024年第4期7卷 517-547页

作者： Youngchan Kim Eunseung Hwang Chang Kai Kaichen Xu Heng Pan Sukjoon hong Optical Nanoprocessing Lab Department of Mechanical EngineeringBK21 FOUR ERICA-ACE CenterHanyang University55 Hanyangdaehak-RoSangnok-GuAnsan 15588Republic of Korea Multiscale Manufacturing Lab J.Mike Walker’66 Department of Mechanical EngineeringTexas A&M UniversityCollege StationTX 77843USA State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310058China

Recently,the increasing interest in wearable technology for personal healthcare and smart virtual/augmented reality applications has led to the development of facile fabrication *** have long been used to develop original solutions to such challenging technological problems due to their remote,sterile,rapid,and site-selective processing of *** this review,recent developments in relevant laser processes are summarized under two separate ***,transformative approaches,such as for laser-induced graphene,are *** addition to design optimization and the alteration of a native substrate,the latest advances under a transformative approach now enable more complex material compositions and multilayer device configurations through the simultaneous transformation of heterogeneous precursors,or the sequential addition of functional layers coupled with other electronic *** addition,the more conventional laser techniques,such as ablation,sintering,and synthesis,can still be used to enhance the functionality of an entire system through the expansion of applicable materials and the adoption of new ***,various wearable device components developed through the corresponding laser processes are discussed,with an emphasis on chemical/physical sensors and energy *** addition,special attention is given to applications that use multiple laser sources or processes,which lay the foundation for the all-laser fabrication of wearable devices.

关键词： Selective laser process Wearable device Transformative approach Laser-induced graphene Ablation Sintering Synthesis

Unraveling links between aging,circadian rhythm and cancer:Insights from evidence-based analysis

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Chinese Journal of Cancer Research 2024年第3期36卷 341-350页

作者： Dechao Feng Yuhan Xiao Jie Wang Ruicheng Wu Zhouting Tuo koo Han Yoo Wuran Wei Dilinaer Wusiman Zhipeng Wang Dengxiong Li Yubo Yang William C.Cho Mang Ke Department of Urology Institute of UrologyWest China HospitalSichuan UniversityChengdu 610041China Division of Surgery&Interventional Science University College LondonLondon W1W 7TSUK Department of Urology Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical UniversityTaizhou 317000China Department of Urology the Second Affiliated Hospital of Anhui Medical UniversityHefei 230601China Department of Urology Kyung Hee UniversitySeoul 130-701South Korea Department of Comparative Pathobiology College of Veterinary MedicinePurdue UniversityWest LafayetteIN47907USA Purdue Institute for Cancer Research Purdue UniversityWest LafayetteIN 47907USA Department of Urology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072China Department of Urology Three Gorges HospitalChongqing UniversityChongqing 404000China Department of Clinical Oncology Queen Elizabeth HospitalHong Kong SARChina

Aging and circadian rhythms have been connected for decades,but their molecular interaction has remained unknown,especially for *** this situation,we summarized the current research actuality and problems in this field using the bibliometric *** in the PubMed and Web of Science databases were ***,there is a rising trend in the publication volume regarding aging and circadian rhythms in the field of *** from USA,Germany,Italy,China and England have greater studies than *** three publication institutions are University of California System,UDICE-French Research Universities and University of Texas *** research hotspots include oxidative stress,breast cancer,melatonin,cell cycle,calorie restriction,prostate cancer and NF-κ*** conclusion,results generated by bibliometric analysis indicate that many approaches involve in the complex interactions between aging and circadian rhythm in *** established and emerging research directions guide our exploration of the regulatory mechanisms of aging and circadian rhythms in cancer and provide a reference for developing new research avenues.

关键词： Aging circadian rhythm human cancer bibliometric analysis oxidative stress

Invasive and non-invasive diagnosis of cirrhosis and portal hypertension

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World Journal of Gastroenterology 2014年第15期20卷 4300-4315页

作者： Moon Young Kim Woo Kyoung Jeong Soon koo baik Department of Internal Medicine Yonsei University Wonju College of MedcineWonju Severance Christan HospitalWonju 220-701South Korea Department of Radiology and Center for Imaging Science Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 440-746South Korea

With advances in the management and treatment of advanced liver disease,including the use of antiviral therapy,a simple,one stage description for advanced fibrotic liver disease has become *** refining the diagnosis of cirrhosis to reflect disease heterogeneity is essential,current diagnostic tests have not kept pace with the progression of this new *** biopsy and hepatic venous pressure gradient measurement are the gold standards for the estimation of hepatic fibrosis and portal hypertension(PHT),respectively,and they have diagnostic and prognostic ***,they are invasive and,as such,cannot be used repeatedly in clinical *** ideal noninvasive test should be safe,easy to perform,inexpensive,reproducible as well as to give numerical and accurate results in real *** should be predictive of long term outcomes related with fibrosis and PHT to allow prognostic ***,many types of noninvasive alternative tests have been developed and are under *** particular,imaging and ultrasound based tests,such as transient elastography,have shown promising *** most of these noninvasive tests effectively identify severe fibrosis and PHT,the methods available for diagnosing moderate disease status are still insufficient,and further investigation is essential to predict outcomes and individualize therapy in this field.

关键词： Hepatic fibrosis Portal hypertension Liver biopsy Hepatic venous pressure gradient Non-invasive test Transient elastography

Connection between inflammation and carcinogenesis in gastrointestinal tract: Focus on TGF-β signaling

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World Journal of Gastroenterology 2010年第17期16卷 2080-2093页

作者： Suntaek hong Ho-Jae Lee Seong Jin Kim Ki-baik Hahm Laboratory of Cancer Cell Biology Lee Gil Ya Cancer and Diabetes InstituteGachon University of Medicine and ScienceIncheon 406-840South Korea Laboratory of Chemoprevention Lee Gil Ya Cancer and Diabetes InstituteGachon University of Medicine and ScienceIncheon 406-840South Korea Laboratory of Cell Regulation and Carcinogenesis Lee Gil Ya Cancer and Diabetes InstituteGachon University of Medicine and ScienceIncheon 406-840South Korea Laboratory of Translational Medicine Lee Gil Ya Cancer and Diabetes InstituteGachon University of Medicine and ScienceIncheon 406-840South Korea Department of Gastroenterology Gachon Graduate School of MedicineIncheon 406-840South Korea

Inflammation is a primary defense process against various extracellular stimuli,such as viruses,pathogens,foods,and environmental *** cells respond to stimuli for short periods of time,it results in acute or physiological ***,if the stimulation is sustained for longer time or a pathological state occurs,it is known as chronic or pathological *** studies have shown that tumorigenesis in the gastrointestinal (GI) tract is closely associated with chronic inflammation,for which abnormal cellular alterations that accompany chronic inflammation such as oxidative stresses,gene mutations,epigenetic changes,and inflammatory cytokines,are shared with carcinogenic processes,which forms a critical cross-link between chronic inflammation and *** growth factor (TGF)-β is a multi-potent cytokine that plays an important role in regulation of cell growth,apoptosis and *** importantly,TGF-β is a strong anti-inflammatory cytokine that regulates the development of effector ***-β has a suppressive effect on carcinogenesis under normal conditions by inhibiting abnormal cell growth,but on the other hand,many GI cancers originate from uncontrolled cell growth and differentiation by genetic loss of TGF-β signaling molecules or perturbation of TGF-β *** a tumor has developed,TGF-β exerts a promoting effect on the tumor itself and stromal cells to enhance cell growth,alter the responsiveness of tumor cells to stimulate invasion and metastasis,and inhibited immune ***,novel development of therapeutic agents to inhibit TGF-β-induced progression of tumor and to retain its growth inhibitory activities,in addition to anti-inflammatory actions,could be useful in *** this review,we discuss the role of TGF-β in inflammation and carcinogenesis of the GI tract related to abnormal TGF-β signaling.

关键词： Inflammation Carcinogenesis Transforming growth factor-β Gastrointestinal tract

Installing a molecular truss beam stabilizes MOF structures

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npj Computational Materials 2022年第1期8卷 1110-1118页

作者： hong Ki Kim Jong-Yeong Jung Gyumin Kang Mu-Hyun baik Eun-Young Choi Department of Chemistry Korea Advanced Institute of Science and Technology(KAIST)Daejeon34141Republic of Korea Center for Catalytic Hydrocarbon Functionalizations Institute for Basic Science(IBS)Daejeon34141Republic of Korea Korea Science Academy of KAIST 105-47 Baegyanggwanmun-roBusanjin-guBusan47162Republic of Korea

Enhancing the stability and durability of metal-organic frameworks(MOFs)is vital for practical applications because many promising MOF materials suffer from phase transitions and/or structural decompositions with humidity being a particularly damaging *** mechanical engineering,the frame of buildings and furniture can be stabilized significantly by installing a truss *** the same principle,we functionalized the organic component of MOF-5 to contain a carbazole moiety that can act as a molecular truss beam by reaching across the corner and forming a stableπ–πinteraction with a phenyl group on the edge position of the *** structural support enhanced the stability of the MOF substantially,allowing the designed MOF to maintain compositional integrity under steam conditions at 90℃for~5 *** unmodified MOF-5 shows clear signs of structural collapse after~1 h.

关键词： beam moiety durability

Expression of E-cadherin and α-catenin in a varicocele-induced infertility rat model

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Asian Journal of Andrology 2011年第3期13卷 470-475,514页

作者： hong koo Ha Hyun Jun Park Nam Cheol Park Department of Urology Pusan National University School of Medicine Busan 602739 Korea Medical Research Institute Pusan National University Hospital Busan 602739 Korea

The roles of E-cadherin and α-catenin were evaluated in the development of varicocele-induced infertility. Analysis of the association between the expression of E-cadherinla-catenin and clinical/pathological parameters was performed. Thirty lO-week-old male rats （experimental group） were used for the experiments; the left renal vein was ligated to form a varicocele. The abdomen was incised in 30 rats （control group） and no procedure was performed on 10 rats （baseline group）. The weights of the left testis, serum reactive oxygen species （ROS）, testosterone, luteinizing hormone （LH）, follicle-stimulating hormone （FSH） and degenerative changes in the seminiferous tubules after 4 and 8 weeks were recorded. The expression of E-cadherin and α-catenin was evaluated by immunohistochemical （IHC） staining and Western blot analysis. The ROS increased in the 8-week experimental group, compared with the baseline and control groups （P〈0.001 for both）. Additionally, FSH significantly increased in the 4- and 8-week experimental group compared with the control groups （P= 0.013 and P= 0.032, respectively）. The ratio of degenerative changes in the seminiferous tubules of the experimental groups increased. The IHC staining showed that the expression of E-cadherin and a-catenin decreased in the 4- and 8-week experimental groups. Similar to the IHC staining, the experimental group had decreased reactivity on Western blot analysis. The expression of E-cadherin and a-catenin was significantly associated with the ROS and degenerative changes in the seminiferous tubules. The results of this study suggest that damage to the blood-testis barrier （BTB） is associated with varicocele-induced male infertility, and that ROS may cause damage to the BTB.

关键词： α-catenin blood-testis barrier E-cadherin varicocele infertility