检索结果-南通市图书馆

Protein & Cell 2015年第9期6卷 693-697页

作者： hong wang (1) (2) Mingzhu wang (1) Na Yang (1) (2) Rui-Ming Xu (1) (2) 1.National Laboratory of Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China 2.University of Chinese Academy of Sciences Beijing 100049 China

The building block of eukaryotic chromatin is the nucleo- some core particle （NCP）, which is consisted of -146 bps of DNA wrapped around an octamer of core histones. A tetra- mer of histone H3 and H4 and two H2A-H2B dimers form the histone octamer （Kornberg, 1974; Luger et al., 1997; Tho- mas and Kornberg, 1975）. During DNA replication, nucleo- some disassembly and reassembly occurs at the replication fork, and histone chaperons CAF-1 and ASF1 are principally responsible for the deposition of histones H3 and H4 onto replicated DNA （Kaufman et al., 1995; Tyler et al., 1999）. ASF1 binds a heterodimeric histone H3-H4 complex through its conserved N-terminal domain （aa 1-155） and impedes the formation of the （H3-H4）2 tetramer both inside the nucleus and in the cytoplasm （English et al., 2005）.

关键词：

Three industries and wastewater and COD discharge of Beijing

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2000年第4期12卷 474-477页

作者： wang Yan 1, wang hong rui 2, NING Da tong 2 (1. Beijing Municipal Research Institute of Environmental Protection, Beijing 100037, China 2. Institute of Environmental Sciences, Beijing Normal University, Beijing 100875, China) 北京市环境保护所北京 1 0 0 0 3 北京师范大学北京 1 0 0 875

With the swift development of economy, the water quality of Beijing is becoming worse day by day and hampers the sustainable development obviously. In this paper, the current conditions of the municipal wastewater structure in the industrial sectors are analysed and discussed in terms of the indicators, such as direct wastewater\|discharge coefficient, complete wastewater\|discharge coefficient, direct discharge coefficient of COD and complete discharge coefficient of COD, by taking a year of 1990s as the base year. Some countermeasures are studied and the corresponding recommendations are put forward in order to improve the water environment in Beijing. This provides a scientific ground for coordinating the relationship between the aquatic environment and economic growth in this city.

关键词： direct wastewater discharge coefficient (DWDC) complete wastewater discharge coefficient (CWDC) direct discharge coefficient of COD(DDC of COD) complete discharge coefficient of COD (CDC of COD)

Effect of primary iris and ciliary body cyst on anterior chamber angle in patients with shallow anterior chamber

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第9期13卷 723-730页

作者： Bing-hong wang Yu-feng YAO Department of Ophthalmology Sir Run Run Shaw Hospital School of MedicineZhejiang UniversityHangzhou 310016China Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University Hangzhou 310016China

Objective:To evaluate the prevalence of primary iris and/or ciliary body cysts in eyes with shallow anterior chamber and their effect on the narrowing of the anterior chamber ***:Among the general physical check-up population,subjects with shallow anterior chambers,as judged by van Herick technique,were recruited for further *** biomicroscope(UBM) was used to detect and measure the cysts located in the iris and/or ciliary body,the anterior chamber depth(ACD),the angle opening distance at 500 μm(AOD500),and the trabecular-iris angle(TIA).A-scan ultrasonography was used to measure the ocular biometry,including lens thickness,axial length,lens/axial length factor(LAF),and relative lens position(RLP).The effect of the cyst on narrowing the corresponding anterior chamber angle and the entire angle was evaluated by the UBM images,ocular biometry,and gonioscopic *** eye with unilateral cyst was compared with the eye without the cyst for further ***:Among the 727 subjects with shallow anterior chamber,primary iris and ciliary body cysts were detected in 250(34.4%) patients;among them 96(38.4%) patients showed unilateral single cyst,21(8.4%) patients had unilateral double cysts,and 42(16.8%) patients manifested unilateral multiple and multi-quadrants *** iris configuration was found in 140 of 361(38.8%) eyes with *** mean size of total cysts was(0.6547±0.2319) *** evaluation of the effect of the cyst size and location on narrowing the corresponding angle to their position,the proportion of the cysts causing corresponding angle narrowing or closure among the cysts larger than 0.8 mm(113/121,93.4%) was found to be significantly higher than that of the cysts smaller than 0.8 mm(373/801,46.6%),and a significant higher proportion was also found in the cysts located at iridociliary sulcus(354/437,81.0%) than in that at the pars plicata(131/484,27.1%).In evaluating the effect of the cyst on the entire anterior ch

关键词： Iris and ciliary body cyst Ultrasound biomicroscope Shallow anterior chamber

Indoor Thermal Environment of Korean Rural Housing Yanbian Region of China in Winter

在线全文

学校读者我要写书评

暂无评论

湖南大学学报（自然科学版） 2009年第S1期36卷 163-166页

作者： wang Xiu-ping1,JIN hong2,wang Yi-han1(1.School of Art and Design,Zhejiang Sci-Tech University,Hangzhou,Zhejiang 310018,China 2.School of Architecture,Harbin Institute of Technology,Harbin,Heilongjiang 150001,China) School of Art and Design Zhejiang Sci.-Tech. University Hangzhou 310018 China School of Architecture Harbin Institute of Technology Harbin 150001 China

For the rural housing in Yanbian region in winter,the indoor thermal environment is bad but the energy consumption is *** in order to solve the problem,the life particularities of the local residents,such as the inhabitation custom and the different living ways,were *** comfortable temperature felt by the local residents was surveyed and summarized according to different age's *** subjective comfortable temperature was calculated by using the thermal comfort formula set up by *** result shows that the comfortable temperature between the survey and the calculation is *** analyzing the survey and the result calculations,the range of local indoor comfortable temperature was given,which provides a reference basis for calculating the thermal comfort and energy efficiency as well as designing green rural houses.

关键词： green rural house thermal comfort environment indoor comfortable temperature energy efficiency

在线全文

学校读者我要写书评

暂无评论

含硫尾砂充填体长期强度性能及其影响因素

中南大学学报（自然科学版） 2018年第6期49卷 1504-1510页

作者：姜关照吴爱祥李红王贻明王洪江北京科技大学金属矿山高效开采与安全教育部重点实验室北京100083 北京科技大学土木与资源工程学院北京100083

针对含硫尾砂胶结充填体经常出现的后期强度劣化现象,进行含硫和无硫尾砂充填体强度对比试验,研究灰砂比和料浆对含硫尾砂充填体长期强度性能的影响,并采用XRD和SEM对含硫尾砂充填体中水化产物进行分析。研究结果表明:尾砂含硫量(质量分... 详细信息

针对含硫尾砂胶结充填体经常出现的后期强度劣化现象,进行含硫和无硫尾砂充填体强度对比试验,研究灰砂比和料浆对含硫尾砂充填体长期强度性能的影响,并采用XRD和SEM对含硫尾砂充填体中水化产物进行分析。研究结果表明:尾砂含硫量(质量分数)为6.1%,主要硫化物为黄铁矿时,充填体120 d强度下降达到47.4%。灰砂比为1:8时,充填体各龄期强度显著增加,后期强度劣化得到改善。灰砂比为1:16时,充填体长期强度稳定在0.85 MPa左右。充填料浆质量分数对充填体强度影响也较为显著,质量分数为74%~76%时,充填体后期强度下降幅度最小。当充填体内部结构较疏松时,次生石膏可以填充水化产物之间的空隙,在一定程度上改善充填体长期强度性能。充填体结构较为致密时,次生石膏会破坏其微观结构,降低充填体后期强度。

关键词：含硫尾砂灰砂比料浆质量分数强度性能硫酸盐侵蚀

Flooding 1990s along the Yangtze River, has it concern of global warming?

在线全文

学校读者我要写书评

暂无评论

Journal of Geographical Sciences 2001年第1期11卷 43-52页

作者： GONG Dao-yi1, ZHU Jin-hong2, wang Shao-wu2 (1. Key Laboratory of Environmental Change and Natural Disaster, Institute of Resources Science, Beijing Normal University, Beijing 100875, China 2. Department of Geophysics, Peking University, Beijing 100871, Beijing Normal University Key Laboratory of Environmental Change and Natural Disaster Institute of Resources Science Beijing China (GRID:grid.20513.35) (ISNI:***) Peking University Department of Geophysics Beijing China (GRID:grid.11135.37) (ISNI:***)

There were a series of severe floods along the middle to lower reaches of the Yangtze River (Changjiang River) in China during the 1990s. The extensive summer (June, July and August) precipitation is mostly responsible for the flooding. The summer rainfall in the 1980s and the 1990s is much higher than that in the previous 3 decades. The means for 1990–1999 is +87.62 mm above normal, marked the 1990s the wettest decade since the 1950s. Six stations with a time span of 1880–1999 are selected to establish century-long rainfall series. This series also shows that the 1990s is the wettest decade during the last 120 years. In the wettest 12 years, four occurred in the 1990s (1991, 1996, 1998 and 1999). Both global and China’s temperature show there is a relative lower air temperature during the 1960–1970s, and a rapid warming in the 1980–1990s. Comparisons of rainfall between 1960–1979 and 1980–1999 show there are dramatic changes. In the cold period 1960–1979, the summer rainfall along the Yangtze River is 3.8 % to 4.7 % below the normal, during the warm period 1980–1999, over 8.4 % to 18.2 % of summer rainfall occurs. Over the whole eastern China, the summer rainfall shows opposite spatial patterns from the 1960–1970s to 1980–1990s. The consistent trend toward more rainfall with global warming is also presented by the greenhouse scenario modeling. A millennial Drought/flood Index for the middle to lower reaches of the Yangtze River showed that although the surplus summer rainfall in the 1990s is the severest during the past 150 years, it is not outstanding in the context of past millennium. Power spectra of the Drought/flood Index show significant interdecadal periods at 33.3 and 11.8 years. Thus, both the natural interdecadal variations and the global warming may play important roles in the frequent floods witnessed during the last two decades.

关键词： summer rainfall Yangtze River global warming interdecadal variation

Land reclamation pattern of iron mine in Tangshan

在线全文

学校读者我要写书评

暂无评论

中国有色金属学会会刊：英文版 2005年第S1期15卷 159-163页

作者： LI Fu-ping~(1,2), LIU Ren-yi~(2), ZHANG Jin-rui~(1,2), GUO Qiao-zhen~(2), wang hong-xin~(2) (1. University of Science and Technology Beijing, Beijing 100083, China 2. Hebei Institute of Technology, Tangshan 063009, China) Univ Sci & Technol Beijing Beijing 100083 Peoples R China Hebei Inst Technol Tangshan 063009 Peoples R China

Based on the analyses of the character of the exploitation of the iron ore resource and its destruction of eco-environment in Tangshan area, this paper puts forward the patterns of land reclamation which fits for this area. The patterns include the reclamation of ecological agriculture, planting directly on the tailing bin without covering soil, reclamation of mine tailings in the pool, and improvement of the soil quality by using tailings etc. Now, over 700hm^2 land has been reclaimed by taking advantage of the pattern in Tangshan and eight typical reclamation districts have been built. The rates of reclamation exceed 80% and have reached the advanced level of the world. Practice has proved that the eco-environment of the ore area has been greatly improved and the remarkable economic and social benefits have been gained.

关键词： land reclamation iron mine reclamation of ecological agriculture improvement of soil quality

Electrophysiological effect of fluoxetine on Xenopus oocytes heterolo-gously expressing human serotonin transporter

在线全文

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2006年第3期27卷 289-293页

作者： hong-wei wang~2 Ci-zhen LI~2 Zhi-fang YANG~2 Yan-qian ZHENG~2 Ying ZHANG~2 Yuan-mou LIU~(2,3) ~2Department of Physiology,Shanghai Jiaotong University Medical School,Shanghai 200025,China DepartmentofPhysiology ShanghaiJiaotongUniversityMedicalSchoolShanghai200025China

Aim:To investigate the electrophysiological effect of fluoxetine on ***:A heterologous expression system was used to introducehuman serotonin transporter(hSERT)into Xenopus oocytes.A 2-electrode volt-age clamp technique was used to study the pharmacological properties ***:hSERT-expressing oocytes were perfused with 10 μmol/Lserotonin(5-HT)to induce *** 5-HT-induced hSERT currentswere dose-dependently reversed by *** RC50(concentration thatachieved a 50% reversal)was approximately 3.12 μmol/*** took moretime to combine with hSERT than 5-HT did,and it was also slow to dissociate *** long-lasting effect of fluoxetine affected normal 5-HT *** significantly prolonged the time constant for 5-HT-induced *** results might be used to explain the long-lasting anti-anxiety effectof fluoxetine in clinical practice,because it increases the concentration of 5-HT inthe synaptic cleft by its enduring suppression of the function of 5-HT ***:Fluoxetine inhibits 5-HT reuptake by competing with 5-HT and chang-ing the normal dynamics of hSERT.

关键词： fluoxetine human serotonin transporter 2-electrode voltage clamp heterologous expression

Mesozoic-Cenozoic tectonic transition in Kuqa Depression-Tianshan,Northwest China:Evidence from sandstone detrital and geochemical records

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2005年第9期48卷 1387-1402页

作者： LI Zhong1, GUO hong2, wang Daoxuan3 & LIN Wei1 1. Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China 2. Tarim Oilfield Branch, CNPC, Korla 841000, China 3. Hefei University of Industry, Tunxilu 193, Hefei 230009, China 1. Institute of Geology and Geophysics Chinese Academy of Sciences 100029 Beijing Chin 2. Tarim Oilfield Branch CNPC 841000 Korla China 3. Hefei University of Industry Tunxilu 193 230009 Hefei Chin

Similar to compositional evolution of sandstone modes and detrital heavy minerals from different profiles in the Kuqa Depression, Northwest China, major element analysis of whole sandstones from the same profiles shows four discontinuous depositional interfaces or periods, respectively corresponding to Lower Triassic\Middle Triassic, Upper Jurassic\Lower Cretaceous, Lower Cretaceous\Paleogene and Miocene\Pliocene, and indicates five-phase evolution during Mesozoic-Cenozoic: (1) From the first to fifth phase, a depositional suite changes from maroon and coarse clastic, through grey-dark grey and fine, red and coarse, red-mottled, interlayered by gypsum, to brown and coarse clastic assemblages, accompanying detrital component evolution in unstable-stable-unstable-very unstable-very unstable assem- blages. It is indicated that carbonate and complex detritus gradually dominate in sandstones in post-Late Jurassic, with rapid reduction of compositional maturity. (2) For major element geo- chemical parameters of whole sandstones, CaO and Fe2 O * 3+MgO contents show a change sequence in high-low-high-higher-highest values, with rapid increasing in post-Late Jurassic. (3) Contra some aggregative indicators for weathering indexes of sandstone detrital component, Al2O3/(CaO+Na2O) and ln(Q/(L+CE)), show a change sequence in low-high-low-lower-lowest ratios, with rapid decreasing in post-Late Jurassic. It is found that sandstone samples of the first, second and later three phases may be distinguished from the A-CN-K and A-CNK-FM diagrams respectively. Therefore, in the Kuqa Depression-Tianshan, the most important discontinuous depositional interface recording paleotectonic and paleoclimatic transition occurred in Early Triassic\Middle Triassic and Late Jurassic\Early Cretaceous, respectively, and, however, tec- tonic differentiations of basin-range system finally result in distinct depositional systems but similar detrital weathering indexes across the Lower Cretaceous\Paleogene

关键词： Tianshan, Kuqa Depression, basin-range, depositional record, tectonic transition, Mesozoic-Cenozoic.

Efficient Differentiation of Embryonic Stem Cells into Neurons in Glial Cell-conditioned Medium under Attaching Conditions

在线全文

学校读者我要写书评

暂无评论

Acta Biochimica et Biophysica Sinica 2005年第7期37卷 480-487页

作者： Hai-Bin TIAN~(1,2) Zeng-Liang BAI~1 hong wang~2 Jian-Quan CHEN~2 Guo-Xiang CHENG~2 1 Institute of Development Biology,School of Life Science,Shandong University,Jinan 250100,China 2 Shanghai Transgenic Research Center,Shanghai 201203,China Institute of Development Biology School of life science Shandong University Jinan 250100 China

Embryonic stem (ES) cells can differentiate into neurons in vitro,which provides hope for thetreatment of some neurodegenerative diseases through cell ***,it remains a challengeto efficiently induce ES cells to differentiate into ***,we show that murine ES cells can efficientlydifferentiate into neurons when cultured in glial cell-conditioned medium (GCM) under attaching conditionswithout the formation of embryoid *** comparison with murine embryonic fibroblast-conditionedmedium,we found that GCM has a positive effect on limiting the generation of non-neuronal cells,such *** addition,compared with suspension conditions,attaching conditions delay the differentiationprocess of ES cells.

关键词： embryonic stem cell glial cell-conditioned medium differentiation neuron attaching conditions