检索结果-南通市图书馆

Optimized operation scheme of flash-memory-based neural network online training with ultra-high endurance

Journal of Semiconductors 2024年第1期45卷 33-37页

作者： Yang Feng Zhaohui Sun Yueran Qi Xuepeng Zhan Junyu Zhang Jing Liu Masaharu kobayashi Jixuan Wu Jiezhi Chen School of Information Science and Engineering(ISE) Shandong UniversityQingdao 266200China Neumem Co. LtdHefei 230093China Key Laboratory of Microelectronic Devices and Integrated Technology Institute of Microelectronics of Chinese Academy of SciencesBeijing 100084China Institute of Industrial Science The University of TokyoTokyoJapan

With the rapid development of machine learning,the demand for high-efficient computing becomes more and more *** break the bottleneck of the traditional Von Neumann architecture,computing-in-memory(CIM)has attracted increasing attention in recent *** this work,to provide a feasible CIM solution for the large-scale neural networks(NN)requiring continuous weight updating in online training,a flash-based computing-in-memory with high endurance(10^(9) cycles)and ultrafast programming speed is *** the one hand,the proposed programming scheme of channel hot electron injection(CHEI)and hot hole injection(HHI)demonstrate high linearity,symmetric potentiation,and a depression process,which help to improve the training speed and *** the other hand,the low-damage programming scheme and memory window(MW)optimizations can suppress cell degradation effectively with improved computing *** after 109 cycles,the leakage current(I_(off))of cells remains sub-10pA,ensuring the large-scale computing ability of *** characterizations are done on read disturb to demonstrate its robust *** processing CIFAR-10 tasks,it is evident that~90%accuracy can be achieved after 109 cycles in both ResNet50 and VGG16 *** results suggest that flash-based CIM has great potential to overcome the limitations of traditional Von Neumann architectures and enable high-performance NN online training,which pave the way for further development of artificial intelligence(AI)accelerators.

关键词： NOR flash memory computing-in-memory endurance neural network online training

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The efficacy of ma-huang-tang (maoto) against influenza

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Health 2011年第5期3卷 300-303页

作者： Mizue Saita Toshio Naito Soushin Boku Yukiko Watanabe Mai Suzuki Fukuko Oka Miki Takahashi Takako Sakurai Eiichiro Sogihara Tomomi Haniu Yuki Uehara Kazunori Mitsuhashi Hiroshi Fukuda Hiroshi Isonuma Keiko Lee hiroyuki kobayashi 不详

In this study, we compared Ma Huang Tang (maoto), a traditional Japanese medicine (Kampo), with antiviral drugs to evaluate their respective and combined effect on the duration of fever and other subjective symptoms of influenza. Forty-five patients enrolled in this randomized control trial had positive type A influenza on rapid influenza antigen test, provided written consent, and sought treatment at Juntendo University Hospital between November 2008 and March 2009. Using a computer-gen- erated list, patients were randomly assigned to one of the four intervention groups: 1): maoto (TJ-27), 9 subjects;2): Tamiflu (oseltamivir), 13 subjects;3): Relenza (zanamivir), 6 subjects;and 4): maoto/oseltamivir combination, 9 subjects. Six outcome measures were evaluated, including fever, myalgia, headache, arthralgia, fatigue, and cough. Statistical differences were determined by the Bonferroni-adjusted t-test for multiple comparisons. Our results showed that there were no significant differences among the four groups in the time-course profile of fever and the number of days until fever resolution since treatment was initiated. In addition, no significant intergroup differences were detected in the number of days until resolution of myalgia, headache, fatigue, and cough. However, the maoto group reported a more rapid improvement in joint pain than the oseltamivir group (P = 0.01). In conclusion, maoto showed comparable efficacy as antiviral medications in reducing fever and influenza symptoms. As serious concerns over the indiscriminate use, adverse reactions, and resistance to current antiviral drugs continue to grow, maoto may serve as an elegant option for the treatment of influenza.

关键词： Ma Huang Tang (Maoto) Influenza Joint Pain Oseltamivir and Zanamivir

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用高效液相色谱法（HPLC）和用银电极作电化学检测快速测定明胶中腺嘌呤和鸟嘌呤含量

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明胶科学与技术 2002年第4期22卷 214-214页

作者： kobayashi,hiroyuki

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Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

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Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi Hideo Kunitoh Shingo Matsumoto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito Yuichiro Ohe Shun-ichi Watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi kobayashi Yohei Miyagi Kazumi Tanaka hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko Matsuda Yoko Shimada Takaaki Mizuno Hiromi Sakamoto Teruhiko Yoshida Yasushi Goto Tatsuya Yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi Hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada Yuichiro Nishida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki Hishida Yasunari Miyazaki Hidemi Ito Mitsuhiro Amemiya Hirohiko Totsuka Haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma kobayashi Kenichi Okubo Kenji Wakai Atsushi Shimizu Masayuki Yamamoto Motoki Iwasaki Koichi Matsuda Johji Inazawa Yuichi Shiraishi Hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko Matsuda Yoichiro Kamatani Ryuji Hamamoto Keitaro Matsuo Takashi Kohno Division of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Division of Medical AI Research and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Respiratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Division of General Thoracic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gastrointestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Division of Thoracic Surgery National Cancer Center HospitalTokyoJapan Department of Thoracic Surgery National Cancer Center Hospital EastChibaJapan Division of Translational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type.

关键词： adenocarcinoma lung Lung

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早稻田大学国际文学馆（村上春树图书馆）

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城市环境设计 2024年第1期147卷 116-123页

作者：渡边启太渡部悠川澄·小林研二写真事务所

我们将早稻田大学校园内的4号楼改建为新的村上春树图书馆，成为一条穿过原有建筑的“木隧道”。木隧道超越了时间和空间，我们将村上春树小说中连接不同维度的“隧道”转译为建筑空间。我们通过将外墙重新漆成白色涂装和原来的建筑，...

我们将早稻田大学校园内的4号楼改建为新的村上春树图书馆，成为一条穿过原有建筑的“木隧道”。木隧道超越了时间和空间，我们将村上春树小说中连接不同维度的“隧道”转译为建筑空间。我们通过将外墙重新漆成白色涂装和原来的建筑，强调了新建的三维木屏风雨棚。雨棚作为隧道入口的指示，也代表了维度之间的边界。这条木制隧道纵向贯穿了原有的楼板，同时用作书架、剧院和演讲厅。20世纪是混凝土的时代，混凝土具有“坚硬”和“冰冷”的特性。相比之下，对于这个图书馆，我们想象了一条隧道，通过使用细腻柔软的木材来保护我们、培育梦想。

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COEDA咖啡厅

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城市环境设计 2024年第1期147卷 162-167页

作者：大庭晋小松克仁川澄·小林研二写真事务所

我们随机堆叠8厘米正方形的桧木棒，制作了一个巨大的树状结构。用碳纤维棒加固（抗拉强度是铁的7倍），就有了一个带有巨大枝杈的“树干”，同时能保证在地震期间减少晃动。项目用地位于可以俯瞰太平洋的悬崖上，通过利用树木状的外观...

我们随机堆叠8厘米正方形的桧木棒，制作了一个巨大的树状结构。用碳纤维棒加固（抗拉强度是铁的7倍），就有了一个带有巨大枝杈的“树干”，同时能保证在地震期间减少晃动。项目用地位于可以俯瞰太平洋的悬崖上，通过利用树木状的外观造型，可以避免使用遮挡景观的外围柱子。

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Theoretical study of current-voltage characteristics of carbon nanotube wire functionalized with hydrogen atoms

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Science China Chemistry 2012年第5期55卷 796-801页

作者： FUENO hiroyuki kobayashi Yoshikazu TANAKA Kazuyoshi Department of Molecular Engineering Graduate School of Engineering Kyoto University Nishikyo-ku Kyoto 615-8510 Japan

A functionalized single-walled carbon nanotube (SWCNT) of a finite length with a ring-like hydrogenation around its surface is designed toward fabrication of a molecular field-effect transistor (FET) device. The molecular wire thus designed is equipped with a quantum dot inside, which is confirmed by theoretical analysis for electronic transport. In particular, the current-voltage (I-V) characteristics under influence of the gate voltage are discussed in detail.

关键词：电压特性碳纳米管线电流氢原子场效应晶体管单壁碳纳米管分子导线有限长度

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Study on Distribution of Four Pseudomonas Species in Living Environment Using Multiplex PCR

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Open Journal of Stomatology 2024年第2期14卷 77-86页

作者： Sachiyo Hayashi Koji Umezawa Osamu Tsuzukibashi Akira Fukatsu Mana Fuchigami Chiaki Komine Hiroshi Yamamoto Mio Hagiwara-Hamano Yukiko Iizuka Satoshi Uchibori Masanobu Wakami Hiroshi Murakami Taira kobayashi Masahiko Fukumoto Takato Nomoto Department of Special Needs Dentistry Nihon University School of Dentistry at Matsudo Chiba Japan Department of Laboratory Medicine for Dentistry for the Compromised Patient Nihon University School of Dentistry at Matsudo Chiba Japan Department of Oral Surgery Nihon University School of Dentistry at Matsudo Chiba Japan Department of Fixed Prosthodontics Nihon University School of Dentistry at Matsudo Chiba Japan Department of Oral Implantology Nihon University School of Dentistry at Matsudo Chiba Japan

Purpose: The genus Pseudomonas is a ubiquitous microorganism frequently detected from immunocompromised patients. The inherent resistance to numerous antimicrobial agents contributes to the opportunistic character of this pathogen exhaustive monitoring of this pathogen is considered of critical importance to public health organizations. The reliable identification method able to distinguish genetic close Pseudomonas species is needed, because these organisms are difficult to differentiate by phenotypic or biochemical methods. The purpose of the present study was to design species-specific primers in order to identify and detect four Pseudomonas species which are frequently detected from the human oral cavities, and to investigate the distribution of these organisms in the living environment using a multiplex PCR. Methods: Polymerase chain reaction (PCR) primers were designed based on partial sequences of the rpoD gene of four Pseudomonas species. Swab samples were collected from fifty washstands, and the distribution of Pseudomonas species was investigated using a conventional PCR at genus level and a multiplex PCR at species level. Results: Multiplex PCR method developed in this study was able to distinguish four Pseudomonas species clearly. The genus Pseudomonas was detected from all samples (100%), whereas P. putida, P, aeruginosa, P. stutzeri and P. fluorescens were detected at 44%, 8%, 4% and 2% in fifty swab samples, respectively. Conclusion: Our developed one-step multiplex PCR method is accurate, specific, cost-effective, time-saving, and works without requiring DNA extraction. It was indicated that washstands were the uninhabitable environment for P. putida, P, aeruginosa, P. stutzeri and P. fluorescens.

关键词： Genus Pseudomonas Multiplex PCR Living Environment

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和线画匹配的阶调再现

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包装工程 2016年第15期37卷 30-34页

作者：耿竞曹从军吴卫国清水浩勝青木直和小林裕幸西安理工大学西安710048 西安市中心医院信息中心西安710003 日本千叶大学

目的为了探索和线画匹配的阶调再现。方法采用明暗描画的非真实感渲染方法将阶调再现这个反映输入明暗和打印出图像的浓度关系的画质因素导入到面积变调的线画中。结果建立了一套自动绘制线画的系统,并发现了和线画匹配的阶调再现。结... 详细信息

目的为了探索和线画匹配的阶调再现。方法采用明暗描画的非真实感渲染方法将阶调再现这个反映输入明暗和打印出图像的浓度关系的画质因素导入到面积变调的线画中。结果建立了一套自动绘制线画的系统,并发现了和线画匹配的阶调再现。结论可以看出要表现深层的感受,即使是灰度值数值段很少的明暗阶调,选择合适的阶调再现也是非常重要的。

关键词：笔墨插图阶调再现线画自动生成

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STOP1 regulatory system: Centered on multiple stress tolerance and cellular nutrientmanagement

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Molecular Plant 2021年第10期14卷 1615-1617页

作者： hiroyuki Koyama Liujie Wu Raj Kishan Agrahari Yuriko kobayashi Molecular PlantApplied Biological Sciences Gifu University501-1193 GifuJapan School of Environment and Life Science Nanning Normal UniversityNanning530001 GuangxiP.R.China.

Transcriptional regulation plays a crucial role in plant adaptation to diverse *** transcription factors(TFs),the so-called master switch TFs or hub TFs,regulate various genes critical for adaptation to different ***1(SENSITIVE TO PROTON RHIZOTOXICITY 1),a zinc-finger TF of Arabidopsis(Arabidopsis thaliana),is one such master/hub TF that transcriptionally regulates multiple stress tolerance(Sadhukhan et al.,2021).STOP1 plays a critical role in tolerance to acid soil syndrome(i.e.,H+and Al3+tolerance)(Iuchi et al.,2007)and hypoxia tolerance(Enomoto et al.,2019),and negatively regulates drought tolerance(Sadhukhan et al.,2019).In addition,Tian et al.

关键词： STOP1 stress Arabidopsis

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