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Possibility to Realize the Brain-Computer Interface from the Quantum Brain Model Based on Superluminal Particles

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Journal of Quantum Information Science 2011年第3期1卷 111-115页

作者： Takaaki Musha Toshiki sugiyama 不详

R. Penrose and S. Hameroff have proposed an idea that the brain can attain high efficient quantum computation by functioning of microtubular structure of neurons in the cytoskelton of biological cells, including neurons of the brain. But Tegmark estimated the duration of coherence of a quantum state in a warm wet brain to be on the order of 10>–13

关键词： Brain-Computer Interface Evanescent Photon Tachyon Quantum Computation Decoherence

Role of drug transporter studies in the drug discovery and development

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Role of drug transporter studies in the drug discovery and d...

World Maps Originating in Asia

第八次全国药物与化学异物代谢学术会议

作者： Yuichi sugiyama Graduate School of Pharmaceutical Sciences The University of TokyoHongoBunkyo-kuTokyo 113-0033Japan

General introduction Drug transporters are expressed in many tissues, such as the intestine, liver, kidney, and the brain, and play key roles in drug absorption, distribution and excretion. The information on the functional characteristics of drug transporters provides important information to allow improvements in drug delivery or drug design by targeting specific transporter proteins. In this presentation, I will summarize the significant role played by drug transporters in drug disposition, focusing particularly on their potential use during the drug discovery and development process. The use of transporter function offers the possibility of delivering a drug to the target organ, avoiding distribution to other organs (thereby reducing

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World Maps Originating in Asia

Membrane transporters and drug response

北京论坛（2005）文明的和谐与共同繁荣——全球化视野中亚洲的机遇与发展

作者： Masaaki sugiyama Kyoto University Japan

The First Afro-Eurasian Map in Human History A single map of vast proportions The map you have before you is known as the Hunyijiangli lidai guodu zhitu (which has been translated in English as the Map ofIntegrated Lands and Regions of Historical Countries and Capitals). That such a map exists in the collection of the library of Ryukoku University is today well *** map was previously owned by the Otani family ofNishi-

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Membrane transporters and drug response

Reduced hemoglobin and increased C-reactive protein are associated with upper gastrointestinal bleeding

第九届全国药物和化学异物代谢学术会议

作者： Yuichi sugiyama Graduate School of Pharmaceutical Sciences The University of TokyoHongoBunkyo-kuTokyo 113-0033 Japan

Drug transporters are expressed in many tissues,such as the intestine,liver,kidney,and the brain,and play key roles in drug absorption,distribution and *** this presentation,I will summarize the significant role played by drug transporters in drug disposition,focusing particularly on their potential use during the drug discovery and development *** use of transporter function offers the possibility of delivering a drug to the target organ,avoiding distribution to other organs(thereby reducing the chance of toxic side-effects),controlling the elimination process,and/or im-

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World Journal of Gastroenterology 2014年第5期20卷 1311-1317页

作者： Minoru Tomizawa Fuminobu Shinozaki Rumiko Hasegawa Akira Togawa Yoshinori Shirai Noboru Ichiki Yasufumi Motoyoshi Takao sugiyama Shigenori Yamamoto Makoto Sueishi Department of Gastroenterology National Hospital Organization Shimoshizu Hospital Yotsukaido City Department of Radiology National Hospital Organization Shimoshizu Hospital Yotsukaido City Department of Surgery National Hospital Organization Shimoshizu Hospital Yotsukaido City Department of Neurology National Hos- pital Organization Shimoshizu Hospital Yotsukaido City Department of Rheumatology National Hospital Organization Shimoshizu Hospital Yotsukaido City Department of Pediatrics National Hospital Organization Shimoshizu Hospital Yotsukaido City

AIM: To investigate the early upper gastrointestinal endoscopy (endoscopy) significantly reduces mortality resulting from upper gastrointestinal (GI) bleeding.

关键词： Receiver operating characteristic Area under curve Sensitivity Specificity Gastrointestinal bleeding

日本设施农业采收机器人研究应用进展及对中国的启示

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智慧农业（中英文） 2022年第2期4卷 135-149页

作者：黄梓宸 sugiyama Saki 京都大学农学研究科京都6068502 浙江大学文学院浙江杭州310058

设施农业智能装备是设施农业稳定、高品质、高效生产的必要保障。日本智能采收装备已有近四十年的研发经验,其发展具有一定启发和借鉴意义。本文综述了日本设施农业采收机器人的研究应用进展,分析了基于农机农艺结合的茄科(番茄、茄子... 详细信息

设施农业智能装备是设施农业稳定、高品质、高效生产的必要保障。日本智能采收装备已有近四十年的研发经验,其发展具有一定启发和借鉴意义。本文综述了日本设施农业采收机器人的研究应用进展,分析了基于农机农艺结合的茄科(番茄、茄子、青椒)、葫芦科(黄瓜、瓜类水果)、芦笋和草莓等10种设施农业采收机器人的采收技术,其中详细对比了番茄、草莓等几种蔬菜历代采收机器人的设计理念及其优点与不足。分析了设施农业采收机器人面临的科学问题及解决方案,总结了未来发展趋势及对中国的启发。本文可为加速推进中国设施农业采收机器人的智慧化、智能化和产业化发展提供借鉴参考。

关键词：农机农艺结合采收技术机器人智慧化研发经验高效生产研究应用进展葫芦科

盆腔后腹膜无缝合法在妇癌淋巴结清扫术中的应用价值

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复旦学报（医学版） 2001年第1期28卷 66-67页

作者：齐聪杉山 上海中医药大学附属曙光医院妇科上海200021 日本久留米大学医学部妇产科

目的　探讨盆腔后腹膜无缝合法在妇癌淋巴结清扫术的应用价值。方法　对 2 18例包括淋巴结清除术在内的各妇癌手术病例进行回顾分析 ,比较了盆腔后腹膜缝合组与无缝合组的术前、术中、术后状况以及并发症的发生率。结果　盆腔后腹膜无... 详细信息

目的　探讨盆腔后腹膜无缝合法在妇癌淋巴结清扫术的应用价值。方法　对 2 18例包括淋巴结清除术在内的各妇癌手术病例进行回顾分析 ,比较了盆腔后腹膜缝合组与无缝合组的术前、术中、术后状况以及并发症的发生率。结果　盆腔后腹膜无缝合法 ,能减少引流管保留天数 ,缩短发热期间和降低淋巴囊肿的发生率。结论　(1)盆腔淋巴结清扫术后 ,后腹膜的缝合可以省略 ;(2 )

关键词：淋巴结清扫术并发症妇科恶性肿瘤癌盆腔后腹膜无缝合法

Evaluation of endoscopic biliary stenting for obstructive jaundice caused by hepatocellular carcinoma

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World Journal of Gastroenterology 2014年第22期20卷 6968-6973页

作者： Gen sugiyama Yoshinobu Okabe Yusuke Ishida Fumihiko Saitou Ryuichi Kawahara Hiroto Ishikawa Hiroyuki Horiuchi Hisafumi Kinoshita Osamu Tsuruta Michio Sata Division of Gastroenterology Department of MedicineKurume University School of MedicineKurume 830-0011Japan

AIM: To review the usefulness of endoscopic biliary stenting for obstructive jaundice caused by hepatocellular carcinoma and identify problems that may need to be addressed.

关键词： Hepatocellular carcinoma Obstructive jaundice Biliary drainage Percutaneous transhepatic biliary drainage Endoscopic biliary stenting

MicroRNA-31 expression in colorectal serrated pathway progression

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World Journal of Gastroenterology 2014年第34期20卷 12346-12349页

作者： Hironori Aoki Katsuhiko Nosho Hisayoshi Igarashi Miki Ito Kei Mitsuhashi Takafumi Naito Eiichiro Yamamoto Tokuma Tanuma Masafumi Nomura Hiroyuki Maguchi Toshiya Shinohara hiromu Suzuki Hiroyuki Yamamoto Yasuhisa Shinomura Center for Gastroenterology Teine-Keijinkai HospitalSapporo 006-0811Japan Department of Gastroenterology Rheumatology and Clinical ImmunologySapporo Medical University School of MedicineSapporo 060-8543Japan Department of Gastroenterology Rheumatology andClinical ImmunologySapporo Medical University School of MedicineSapporo 060-8543Japan Department of Pathology Teine-KeijinkaiHospitalSapporo 006-0811Japan Department of Molecular Biology SapporoMedical University School of MedicineSapporo 060-8543Japan Division of Gastroenterology and Hepatology Department of Internal MedicineSt. Marianna University School of MedicineKawasaki 216-8511Japan

MicroRNAs have been increasingly recognized as useful biomarkers for colorectal cancers(CRC).We have recently observed that microRNA-31(miR-31)expression is associated with BRAF mutation and prognosis in ***,high miR-31 expression is frequently detected in sessile serrated adenomas compared with hyperplastic polyps(HPs).These results suggest that miR-31 may contribute to the progression of serrated *** a follow-up colonoscopy,we observed the case of a 75-year-old man with a 7-mm flat-elevated lesion in the cecum and diagnosed the lesion as an early invasive carcinoma with serrated *** specimens were obtained from the representative areas to compare the molecular alterations in the carcinoma component with those in the HP *** miR-31 expression was observed in the carcinoma component(57-fold increase)and the HP component(8-fold increase)compared with the paired normal mucosa,suggesting that miR-31 may be one of the key molecules in serrated pathway progression.

关键词： BRAF Colorectal carcinoma MicroRNA-31 MLH1 microsatellite instability Serrated pathway