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Rumex dentatus could be a potent alternative to treatment of microbial infections and of breast cancer

Journal of Traditional Chinese Medicine 2019年第6期39卷 772-779页

作者： Riffat Batool Ejaz Aziz hina salahuddin Javed Iqbal Saira Tabassum Tariq Mahmood University Institute of Biochemistry and Biotechnology Pir Mehr Ali Shah Arid Agriculture University RawalpindiRawalpindiPunjab 46000Pakistan Department of Botany Government Degree College KhanpurHaripur 22650Pakistan Department of Zoology University of OkaraOkara 56300Pakistan National University of Technology School of Applied Sciences and HumanitiesNational University of TechnologyIslamabad 42000Pakistan Department of Plant Sciences Faculty of Biological SciencesQuaid-i-Azam UniversityIslamabad 45320Pakistan

OBJECTIVE:To investigate the phytochemicals and in vitro antioxidant,antimicrobial and cytotoxic potential of Rumex dentatus(***)leaf ***:The total phenolics and flavonoids content of *** extracts were evaluated by the Folin-Ciocalteu and aluminum chloride colorimetric methods *** potential of studied plant extracts was assessed through 2,2-diphenyl-1-picrylhydrazyl radical scavenging capacity,total reducing power and total antioxidant ***,antibacterial and antifungal capacity was also evaluated by disc diffusion method against six clinically isolated multi-drug resistant bacterial strains as well as six fungal ***,cell cytotoxicity was also evaluated through3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide ***:Ethanol extract showed highest total phenolic[(38.9±1.5)μg gallic acid equivalent/mg]and total flavonoids[(17.2±1.9)μg quercetin equivalent/mg]*** assays indicated that ethanol and methanol extracts possess potent antioxidant ***,it was observed that ethanol and hexane extracts have the potential to inhibit most of the tested multi-drug resistant bacterial strains while methanol,chloroform and hexane extracts could inhibit the growth of pathogenic fungal strains *** all the studied extracts,ethanolic extract showed highest cytotoxicity against MCF-7 cell line then Hep-2 and DU-145 cell lines by MTT assay with lowest IC50 of 47.3μg/m ***:These results suggest that *** could be a potent alternative candidate for treatment of microbial infections and for breast cancer treatment.

关键词： Rumex Atioxidants Anti-infective agents Drug resistant,multiple Cytotoxins

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In vitro antioxidant and anti-cancer activities and phytochemical analysis of Commelina benghalensis L. root extracts

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Asian Pacific Journal of Tropical Biomedicine 2020年第9期10卷 417-425页

作者： Riffat Batool Ejaz Aziz Javed Iqbal hina salahuddin Benny Kwong-Huat Tan Saira Tabassum Tariq Mahmood University Institute of Biochemistry and Biotechnology PMAS-UAAR RawalpindiPakistan Department of Botany GDC KhanpurHaripur Pakistan Department of Plant Sciences Faculty of Biological SciencesQuaid-i-Azam UniversityIslamabad-45320Pakistan Department of Zoology University of OkaraOkaraPakistan Department of Pharmacology Yong Loo Lin School of MedicineNational University of SingaporeSingapore Department of Biotechnology Faculty of Biological SciencesQuaid-i-Azam UniversityIslamabad-45320Pakistan

Objective:To explore antioxidant potential,anti-cancer activity,and phytochemicals of Commelina benghalensis ***:The roots of Commelina benghalensis were extracted in different solvents(methanol,ethanol,benzene,chloroform,n-hexane)with a range of *** activity was evaluated by reducing power assay,DPPH radical scavenging activity and phosphomolybdenum method,cytotoxicity by MTT assay,apoptotic and cell cycle analysis by flow cytometry,migratory and invasive potential by wound scratch assay and invasion assay,respectively,functional groups analysis by FT-IR spectroscopy and phytochemicals by aluminum chloride colorimetric and FolinCiocalteu ***:The extracts showed worthy antioxidant *** chloroform extract demonstrated the most significant cytotoxic effect on MDA-MB-231(breast cancer)cell line,induced apoptosis and reduced migratory and invasive potential of MDA-MB-231 *** and ethanol extracts presented good yield of total phenolic and total flavonoid *** FTIR spectroscopic studies revealed different characteristic peak values with various functional compounds such as alkenes,alkanes,aliphatic amines,aromatics,alkyl halides,carboxylic acid,alcohols,ester,aldehydes and ***:The results demonstrate the potential use of Commelina benghalensis as a good antioxidant with significant anticancer effect.

关键词： Commelina benghalensis Anti-cancer Antioxidant FT-IR

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A Traffic-Aware and Cluster-Based Energy Efficient Routing Protocol for IoT-Assisted WSNs

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Computers, Materials & Continua 2024年第8期80卷 1831-1850页

作者： hina Gul Sana Ullah Ki-Il Kim Farman Ali Department of Computer and Software Technology University of SwatMingora19130Pakistan Department of Computer Science and Engineering Chungnam National UniversityDaejeon34134Republic of Korea Department of Applied AI Sungkyunkwan UniversitySeoul03063Republic of Korea

The seamless integration of intelligent Internet of Things devices with conventional wireless sensor networks has revolutionized data communication for different applications,such as remote health monitoring,industrial monitoring,transportation,and smart *** and reliable data routing is one of the major challenges in the Internet of Things network due to the heterogeneity of *** paper presents a traffic-aware,cluster-based,and energy-efficient routing protocol that employs traffic-aware and cluster-based techniques to improve the data delivery in such *** proposed protocol divides the network into clusters where optimal cluster heads are selected among super and normal nodes based on their residual *** protocol considers multi-criteria attributes,i.e.,energy,traffic load,and distance parameters to select the next hop for data delivery towards the base *** performance of the proposed protocol is evaluated through the network simulator *** different traffic rates,number of nodes,and different packet sizes,the proposed protocol outperformed LoRaWAN in terms of end-to-end packet delivery ratio,energy consumption,end-to-end delay,and network *** 100 nodes,the proposed protocol achieved a 13%improvement in packet delivery ratio,10 ms improvement in delay,and 10 mJ improvement in average energy consumption over LoRaWAN.

关键词： Internet of Things wireless sensor networks traffic load clustering routing energy efficiency

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Posture Detection of Heart Disease Using Multi-Head Attention Vision Hybrid(MHAVH)Model

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Computers, Materials & Continua 2024年第5期79卷 2673-2696页

作者： hina Naz Zuping Zhang Mohammed Al-Habib Fuad A.Awwad Emad A.A.Ismail Zaid Ali Khan School of Computer Science and Engineering Central South UniversityChangsha410003China Department of Quantitative analysis College of Business AdministrationKing Saud UniversityP.O.Box 71115Riyadh11587Saudi Arabia Electrical and Computer Engineering University of VictoriaVictoriaV9A1B8Canada

Cardiovascular disease is the leading cause of death *** disease causes loss of heart muscles and is also responsible for the death of heart cells,sometimes damaging their functionality.A person’s life may depend on receiving timely assistance as soon as ***,minimizing the death ratio can be achieved by early detection of heart attack(HA)*** the United States alone,an estimated 610,000 people die fromheart attacks each year,accounting for one in every four ***,by identifying and reporting heart attack symptoms early on,it is possible to reduce damage and save many lives *** objective is to devise an algorithm aimed at helping individuals,particularly elderly individuals living independently,to safeguard their *** address these challenges,we employ deep learning *** have utilized a vision transformer(ViT)to address this ***,it has a significant overhead cost due to its memory consumption and computational complexity because of scaling dot-product ***,since transformer performance typically relies on large-scale or adequate data,adapting ViT for smaller datasets is more *** response,we propose a three-in-one steam model,theMulti-Head Attention Vision Hybrid(MHAVH).Thismodel integrates a real-time posture recognition framework to identify chest pain postures indicative of heart attacks using transfer learning techniques,such as ResNet-50 and VGG-16,renowned for their robust feature extraction *** incorporatingmultiple heads into the vision transformer to generate additional metrics and enhance heart-detection capabilities,we leverage a 2019 posture-based dataset comprising RGB images,a novel creation by the author that marks the first dataset tailored for posture-based heart attack *** the limited online data availability,we segmented this dataset into gender categories(male and female)and conducted testing on both segmented and original dat

关键词： Image analysis posture of heart attack(PHA)detection hybrid features VGG-16 ResNet-50 vision transformer advance multi-head attention layer

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A review:Health benefits and physicochemical characteristics of blended vegetable oils

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Grain & Oil Science and Technology 2024年第2期7卷 113-123页

作者： hina Daud Memon Sarfaraz Ahmed Mahesar Sirajuddin Huseyin Kara Syed Tufail Hussain Sherazi Mohammad Younis Talpur National Centre of Excellence in Analytical Chemistry University of SindhJamshoro 76080Pakistan International Center for Chemical and Biological Sciences HEJ Research Institute of ChemistryUniversity of KarachiKarachi 75270Pakistan Department of Chemistry Faculty of ScienceSelcuk UniversityKonya 42075Turkey Dr.M.A.Kazi Institute of Chemistry University of SindhJamshoro 76080Pakistan

Oil blending is the method of choice used worldwide to improve oxidative stability and nutritional *** is no such edible oil/fat that meets all the recommendations from the health point of *** fatty acid composition of vegetable oils decides the fate of the *** single oil is unable to provide a balanced amount of fatty acids(FAs)required/recommended on a daily intake *** oils/fats is an appropriate procedure of physically mixing multiple oils in suitable proportions which may provide functional lipids with improved antioxidant potential and desirable physical and chemical *** review piled up the accessible data on the blending of diverse oils/fats in the combination of binary,ternary,quaternary,or other types of oils into a single blended *** can be found very convincing towards appropriate FA profile,enhancement in physicochemical characteristics,and augmented stability for the period of storage or when used as cooking/frying processes which could ultimately serve as an effectual dietary intervention towards the health protectiveness.

关键词： Vegetable oil Oil blending Physicochemical properties Nutritional benefits

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Impact of Cattaneo-Christov Heat Flux in the Nanofluid Flow over an Inclined Permeable Surface with Irreversibility Analysis

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Journal of Applied Mathematics and Physics 2024年第4期12卷 1582-1595页

作者： Muhammad Ramzan hina Gul Department of Computer Science Bahria University Islamabad Pakistan

This study discusses the magnetohydrodynamic nanofluid flow over an inclined permeable surface influenced by mixed convection, and Cattaeo-Christov heat flux. The heat transfer analysis is performed in the presence of a heat source/sink and thermal stratification. To gauge the energy loss during the process, an irreversibility analysis is also performed. A numerical solution to the envisaged problem is obtained using the bvp4c package of MATLAB. Graphs are drawn to assess the consequences of the arising parameters against the associated profiles. The results show that an augmentation in the magnetic field and nanomaterial volume fraction results in an enhancement in the temperature profile. A strong magnetic field can significantly reduce the fluid velocity. The behavior of the Skin friction coefficient against the different estimates of emerging parameters is discussed. .

关键词： Nanofluid Flow Cattaneo-Christov Heat Flux Permeable Surface Mixed Convection Heat Source/Sink Thermal Stratification

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Association of spiritual well-being with quality of life among undergraduate nursing students

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Journal of Integrative Nursing 2024年第1期6卷 49-54页

作者： Ahmad SHAHID hina HUSSAIN Nazia SHUAIB Ahmad RASOOL Fatima YOUNIS Zoya NASAB Department of Nursing Professional College of Nursing and Health SciencesIslamabadPakistan Department of Nursing Rawal Institute of Health SciencesIslamabadPakistan Department of Nursing Rawal College of NursingIslamabadPakistan School of Nursing and Health Zhengzhou UniversityZhengzhouChina

Objective:The study was conducted with the aim of determining the spiritual well-being(SWB)of nursing students and its association with quality of life(QOL).Materials and Methods:A cross-sectional analytical study was conducted with a sample size of 504 nursing students collected from January 2023 to March 2023 in the nursing institutes of Khyber Pakhtunkhwa,Pakistan,using convenient sampling techniques.A Spiritual Health and Life-Orientation Measure(SHALOM)questionnaire for SWB and K-27 QOL(K-27 QOL)instrument were used for data collection that contains three ***:The number of female participants was in the majority(50.4%)compared to male nurses(49.6%).The overall mean score of SWB of the students was 3.79±0.48,while the mean K-27 QOL score was 3.73±*** were significant differences between the groups of gender(P=0.001),while no significant difference within the groups of semester(P=0.061)and college status(0.285).In QOL,there were significant differences within the groups of semester(P=0.000)and college status(P=0.036)while no significant difference in gender category(P=0.480).SHALOM score is positively and moderately correlated with QOL score(r=0.597,P<0.05).Conclusion:Spiritual practices are one of the important factors that are associated positively with QOL,therefore to enhance the QOL,it will require spiritual practices.

关键词： Nursing education nursing student quality of life spiritual nursing care spirituality well‑being

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The Experience and Impact of a Fitbit-Based Physical Activity and Sleep Hygiene Intervention for Older Adults Experiencing Cognitive Decline

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Advances in Aging Research 2024年第3期13卷 41-59页

作者： Kate Walker Chris Griffiths Jen Yates Louise Birkett-Swan Farah hina Chee Siang Ang Research and Innovation Department Northamptonshire Healthcare NHS Foundation Trust Northampton UK Institute of Mental Health University of Nottingham Nottingham UK Dementia and Older People’ s Psychology Provision Northamptonshire Healthcare NHS Foundation Trust Northampton UK School of Computing University of Kent Canterbury UK

Objectives: This study aimed to understand the experience and impact of a physical activity and sleep wrist-worn tracker (Fitbit)-based healthy lifestyle intervention for older patients attending a memory assessment service, who are experiencing cognitive impairment but do not receive a dementia diagnosis. Methods: A qualitative design was employed. Semi-structured interviews were conducted with a purposeful sample of thirteen participants recruited from a memory assessment service. Thematic analysis, that was data driven and inductive, was undertaken to analyse the data. Results: Two global themes were developed. “Understanding exercise and sleep as part of my lifestyle” was made up of themes representing how participants viewed exercise and sleep as part of their lifestyles in terms of acknowledging the positive impacts and the barriers to exercise and sleep. The second global theme “Understanding my experience of the healthy lifestyle intervention” was made up of themes that identified the positive impact of the intervention regarding improving health and wellbeing, enabling validation of proactive behaviours and motivation to engage in healthy lifestyle behaviours, so promoting positive behaviour change. Conclusion: Patients experiencing age-related cognitive impairment, applied and benefited from a healthy lifestyle Fitbit-based intervention to facilitate and promote physical activity, better sleep hygiene and healthy lifestyles.

关键词： Cognitive Impairment Healthy Lifestyle Intervention Fitbit Health and Wellbeing Behaviour Change

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“Active Feedback” Fitbit-Based Physical Activity and Sleep Hygiene Intervention for Memory Assessment Service (MAS) Patients with Cognitive Deficits: Feasibility, Acceptability, Sleep Quality, Stress, and Wellbeing Outcomes

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Advances in Aging Research 2024年第4期13卷 61-74页

作者： Chris Griffiths Farah hina Chee Siang Ang Louise Birkett-Swan Casey Bonham Lauren Currell Emily Ward Natasha Stace-Wood Jessica Plumbridge Northamptonshire Healthcare NHS Foundation Trust Northampton UK School of Computing University of Kent Canterbury UK

Research Background: Compared to the general population, people experiencing age-related cognitive decline are more likely to have low levels of physical activity and sleep problems. Sufficient physical activity and quality sleep are protective factors against cognitive decline and poor health and can improve coping with stressors. The “Active Feedback” intervention comprises a wearable activity and sleep tracker (Fitbit), access to Fitbit software healthy lifestyle software apps;one session with Memory Assessment Service (MAS) staff providing physical activity and sleep hygiene advice and two further engagement, discussion, and feedback sessions. Purpose/Aim: This study investigates the acceptability and feasibility of Active Feedback and the effect on stress, mental wellbeing, and sleep quality, and the links between these factors. Methods: An open-label patient cohort design with no control group was used. Pre-intervention, 4-week and 8-week intervention assessments were performed using participant self-report measures: Perceived Stress Scale (PSS), Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS), and Sleep Conditioning Index (SCI). Twenty-five participants completed an eight-week three-session intervention (18 males and 7 females), with the age range of 66 - 84 years old, and average age of 73.8 years (SD = 5.09). Fifteen participants had a diagnosis of MCI, ten participants did not. Results: There were non-significant improvements in SCI scores from 21.0 (SD = 8.84) to 21.6 (SD = 6.20) at 8 weeks, PSS scores from 17.5 (SD = 5.89) to 17.0 (SD = 6.20) at 8 weeks, and WEMWBS scores from 46.9 (SD = 9.23) to 48.8 (SD = 9.69) at 8 weeks. There were negative correlations between WEMWBS and PSS. Conclusion: Active Feedback intervention was found to be feasible and acceptable. Active Feedback could be enhanced to include motivational interviewing and goal setting.

关键词： Fitbit Tracker MCI Exercise Insomnia Physical Activity Wearables Sleep

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Analysis of Combined Convective and Viscous Dissipation Effects for Peristaltic Flow of Rabinowitsch Fluid Model

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Journal of Bionic Engineering 2017年第1期14卷 182-190页

作者： hina Sadaf Sohail Nadeem Department of Mathematics Quaid-i-Azam University Islamabad 44000 Pakistan

In this article, mathematical modeling for peristaltic flow of Rabinowitsch fluid model is considered in a non-uniform tube with combined effects of viscous dissipation and convective boundary conditions. Wall properties analysis is also taken into account. Non-dimensional differential equations are simplified by using the well-known assumptions of low Reynolds number and long wavelength. The influence of various parameters connected with this flow problem such as rigidity parameter E1, stiffness parameter E2, viscous damping force parameter E3, Brickman number and Biot number are plotted for velocity distribution, temperature profile and for stream function. Results are plotted and discussed in detail for shear thinning, shear thickening and for viscous fluid. It is found that velocity profile is an increasing function of rigidity parameter, stiffness parameter, and viscous damping force parameter for shear thinning and for viscous fluid, due to the less resistance offered by the walls but, quite opposite behavior is depicted for shear thickening fluids. It is seen that Brickman number relates to the viscous dissipation effects, so it contributes in enhancing fluid temperature for all cases.

关键词： peristaltic flow non-uniform tube viscous dissipation convective boundary condition exact solution,non-newtonian fluid

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