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Caffeine therapy in preterm infants

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World Journal of Clinical Pediatrics 2015年第4期4卷 81-93页

作者： hesham abdel-hady Nehad Nasef Abd Elazeez Shabaan Islam Nour Neonatal Intensive Care Unit Mansoura University Children's Hospital

Caffeine is the most commonly used medication for treatment of apnea of prematurity. Its effect has been well established in reducing the frequency of apnea, intermittent hypoxemia, and extubation failure in mechanically ventilated preterm infants. Evidence for additional short-term benefits on reducing the incidence of bronchopulmonary dysplasia and patent ductus arteriosus has also been suggested. Controversies existamong various neonatal intensive care units in terms of drug efficacy compared to other methylxanthines, dosage regimen, time of initiation, duration of therapy, drug safety and value of therapeutic drug monitoring. In the current review, we will summarize the available evidence for the best practice in using caffeine therapy in preterm infants.

关键词： Apnea Caffeine Preterm Methylxanthines

Language and cognitive outcome for high-risk neonates at the age of 2-3 years-experience from an Arab Country

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World Journal of Clinical Pediatrics 2017年第1期6卷 24-33页

作者： Tamer Abou-Elsaad hesham abdel-hady Hemmat Baz Doaa ElS habrawi Phoniatric Unit ORL DepartmentFaculty of MedicineMansoura University Neonatal Intensive Care Unit Mansoura University Children’s Hospital Phoniatric Unit ORL DepartmentMansoura General Hospital

AIM To investigate the effect of different neonatal risk factors on different language parameters as well as cognitive abilities among Arabic speaking Egyptian children at the age of two to three years of life and to find out which risk factor(s) had the greatest impact on language and cognitive *** This retrospective cohort study was conducted on 103 children with age range of 2-3 years(median age 31 mo).They were 62 males and 41 females who were exposed to different high-risk factors in the perinatal period,with exclusion of metabolic disorders,sepsis/meningitis,congenital anomalies and chromosomal *** studied children were subjected to a protocol of language assessment that included history taking,clinical and neurological examination,audiological evaluation,assessment of language using modified preschool language scale-4,IQ and mental age assessment and assessment of social *** The studied children had a median gestational age of 37 wk,median birth weight of 2.5 *** distribution of the high-risk factors in the affected children were prematurity in 25 children,respiratory distress syndromein 25 children,hypoxic-ischemic encephalopathy in 15 children,hyperbilirubinemia in 10 children,hypoglycemia in 13 children,mixed risk factors in 15 *** results revealed that high-risk neonatal complications were associated with impairment of different language parameters and cognitive abilities(P < 0.05).The presence of prematurity,in relation to other risk factors,increases the risk of language and cognitive delay significantly by 3.9 *** Arabic-speaking children aged 2-3 years who were exposed to high-risk conditions in the perinatal period are likely to exhibit delays in the development of language and impairments in cognitive *** most significant risk factor associated with language and cognitive impairments was prematurity.

关键词： High-risk neonates Prematurity Arabic language Cognition Child disability

Acute flaccid paralysis in a patient with sacral dimple

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World Journal of Clinical Pediatrics 2013年第3期2卷 26-30页

作者： Mohammed Mostafa Nehad Nasef Tarik Barakat Amany K El-Hawary hesham abdel-hady Faculty of Medicine Mansoura University Children’s Hospital Department of Pediatrics Faculty of MedicineUniversity of Mansoura

Sacral dimples are the most common cutaneous anomaly detected during neonatal spinal examination. Congenital dermal sinus tract, a rare type of spinal dysraphism, occurs along the midline neuraxis from occiput down to the sacral region. It is often diagnosed in the presence of a sacral dimple together with skin signs, local infection, meningitis, abscess, or abnormal neurological examination. We report a case of acute flaccid paralysis with sensory level in a 4 mo old female infant with sacral dimple, diagnosed by magnetic resonance imaging to be a paraspinal subdural abscess. Surgical exploration revealed a congenital dermal sinus tract extending from the subdural abscess down to the sacral dimple and open to the exterior with a minute opening.

关键词： Paralysis Paraplegia Spinal dysraphism Spinal cord compression Spinal epidural abscess

Design of Automated Opinion Mining Model Using Optimized Fuzzy Neural Network

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Computers, Materials & Continua 2022年第5期71卷 2543-2557页

作者： Ala’A.Eshmawi hesham Alhumyani Sayed abdel Khalek Rashid A.Saeed Mahmoud Ragab Romany F.Mansour Department of Cybersecurity College of Computer Science and EngineeringUniversity of JeddahJeddahSaudi Arabia Department of Computer Engineering College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Mathematics Faculty of SciencesTaif UniversityTaif21944Saudi Arabia Centre for Artificial Intelligence in Precision Medicine King Abdulaziz UniversityJeddah21589Saudi Arabia Department of Mathematics Faculty of ScienceNew Valley UniversityEl-Kharga72511Egypt

Sentiment analysis or Opinion Mining (OM) has gained significant interest among research communities and entrepreneurs in the recentyears. Likewise, Machine Learning (ML) approaches is one of the interestingresearch domains that are highly helpful and are increasingly applied in severalbusiness domains. In this background, the current research paper focuses onthe design of automated opinion mining model using Deer Hunting Optimization Algorithm (DHOA) with Fuzzy Neural Network (FNN) abbreviatedas DHOA-FNN model. The proposed DHOA-FNN technique involves fourdifferent stages namely, preprocessing, feature extraction, classification, andparameter tuning. In addition to the above, the proposed DHOA-FNN modelhas two stages of feature extraction namely, Glove and N-gram ***, FNN model is utilized as a classification model whereas GTOA isused for the optimization of parameters. The novelty of current work is thatthe GTOA is designed to tune the parameters of FNN model. An extensiverange of simulations was carried out on the benchmark dataset and the resultswere examined under diverse measures. The experimental results highlightedthe promising performance of DHOA-FNN model over recent state-of-the-arttechniques with a maximum accuracy of 0.9928.

关键词： Opinion mining sentiment analysis fuzzy neural network metaheuristics feature extraction classification

Combining Committee-Based Semi-Supervised Learning and Active Learning

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Journal of Computer Science & Technology 2010年第4期25卷 681-698页

作者： Mohamed Farouk abdel hady Friedhelm Schwenker Institute of Neural Information Processing University of Ulm

Many data mining applications have a large amount of data but labeling data is usually difficult, expensive, or time consuming, as it requires human experts for annotation. Semi-supervised learning addresses this problem by using unlabeled data together with labeled data in the training process. Co-Training is a popular semi-supervised learning algorithm that has the assumptions that each example is represented by multiple sets of features （views） and these views are sufficient for learning and independent given the class. However, these assumptions axe strong and are not satisfied in many real-world domains. In this paper, a single-view variant of Co-Training, called Co-Training by Committee （CoBC） is proposed, in which an ensemble of diverse classifiers is used instead of redundant and independent views. We introduce a new labeling confidence measure for unlabeled examples based on estimating the local accuracy of the committee members on its neighborhood. Then we introduce two new learning algorithms, QBC-then-CoBC and QBC-with-CoBC, which combine the merits of committee-based semi-supervised learning and active learning. The random subspace method is applied on both C4.5 decision trees and 1-nearest neighbor classifiers to construct the diverse ensembles used for semi-supervised learning and active learning. Experiments show that these two combinations can outperform other non committee-based ones.

关键词： data mining classification active learning co-training semi-supervised learning ensemble learning randomsubspace method decision tree nearest neighbor classifier

Acute diseases:An epidemiologic perspective

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Journal of Acute Disease 2023年第1期12卷 1-9页

作者： abdel-hady El-Gilany Hala Abou-ElWafa Public Health and Preventive Medicine Public Health and Community Medicine DepartmentFaculty of MedicineMansoura UniversityMansouraEgypt Industrial Medicine and Occupational Health Public Health&Community Medicine DepartmentFaculty of MedicineMansoura UniversityMansouraEgypt

Many underdeveloped countries still struggle with the public health issue of acute illnesses,especially with the emergence of injuries as a major category of acute *** of the acute disease is challenging particularly when it occurs as an outbreak,either in isolation or as part of a wider *** narrative review summarizes the definition,epidemiologic transition,pattern and modes of spread,classification,epidemiologic measures,community burden,prevention,control,and future challenges of acute *** review is to provide a reference for epidemiologists,clinicians,researchers,and policymakers.

关键词： Acute disease Spread Transition Classification Burden

Optimized Tuned Deep Learning Model for Chronic Kidney Disease Classification

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Computers, Materials & Continua 2022年第2期70卷 2097-2111页

作者： R.H.Aswathy P.Suresh Mohamed Yacin Sikkandar S.abdel-Khalek hesham Alhumyani Rashid A.Saeed Romany F.Mansour Department of Computer Science and Engineering KPR Institute of Engineering and TechnologyCoimbatore641407India Department of Medical Equipment Technology College of Applied Medical SciencesMajmaah UniversityAlMajmaah11952Saudi Arabia Department of Mathematics College of ScienceTaif UniversityTaif21944Saudi Arabia Department of Computer Engineering College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Mathematics Faculty of ScienceNew Valley UniversityEl-Kharga72511Egypt

In recent times,Internet of Things(IoT)and Cloud Computing(CC)paradigms are commonly employed in different healthcare *** gadgets generate huge volumes of patient data in healthcare domain,which can be examined on cloud over the available storage and computation resources in mobile *** Kidney Disease(CKD)is one of the deadliest diseases that has high mortality rate across the *** current research work presents a novel IoT and cloud-based CKD diagnosis model called Flower Pollination Algorithm(FPA)-based Deep Neural Network(DNN)model abbreviated as *** steps involved in the presented FPA-DNN model are data collection,preprocessing,Feature Selection(FS),and ***,the IoT gadgets are utilized in the collection of a patient’s health *** proposed FPA-DNN model deploys Oppositional Crow Search(OCS)algorithm for FS,which selects the optimal subset of features from the preprocessed *** application of FPA helps in tuning the DNN parameters for better classification *** simulation analysis of the proposed FPA-DNN model was performed against the benchmark CKD *** results were examined under different *** simulation outcomes established the superior performance of FPA-DNN technique by achieving the highest sensitivity of 98.80%,specificity of 98.66%,accuracy of 98.75%,F-score of 99%,and kappa of 97.33%.

关键词： Deep learning chronic kidney disease IoT cloud computing feature selection classification

Challenges of COVID-19 prevention and control: A narrative review

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Journal of Acute Disease 2022年第4期11卷 127-132页

作者： abdel-hady El-Gilany Eman Sameh Hala SAbou-ElWafa Public Health&Preventive Medicine Mansoura UniversityEgypt Public Health&Preventive Medicine Minia UniversityEgypt Industrial Medicine and Occupational Health Mansoura UniversityEgypt

This narrative review aims to highlight some of the factors contributing to challenges faced by many countries in controlling the spread of COVID-19 pandemic that continues to rage around the world,especially after stoppage of official prevention and control activities.A literature search was conducted on PubMed,and Google using search terms“COVID-19”,“challenges”,“prevention”,and“control”in different ***-19 prevention and control challenges are related to health-system,vaccines,administration,and society *** the spread of COVID-19 necessitates cooperation between community leaders,healthcare professionals,religious leaders,and the public.

关键词： COVID19 Challenges Prevention Control Vaccine Health system Administration Social Culture

Clinico-epidemiological features of dengue fever in Saudi Arabia

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Asian Pacific Journal of Tropical Medicine 2010年第3期3卷 220-223页

作者： abdel-hady El-Gilany abdelaziz Eldeib Sabri Hammad Public Health Family and Community Medicine DepartmentCollege of Medicine in Al-HassaKing Faisal University Ministry of Health

Objective:To highlight some clinical and epidemiological features of dengue ***: All patients who were admitted to hospitals in Holly Mecca City,Saudi Arabia and were confirmed as dengue fever(DF) or dengue hemorrhagic fever(DHF) were included in this study. The data were collected from patient files and through direct interview with patients or their *** were followed through their hospital *** laboratory investigations were done and diagnosis was confirmed by ***:Most of cases admitted in stable condition(94.37%) and only one case(1.41%) ***-1 and 3 types were the prevalent dengue viruses and cases in age group 16-44 were the most frequent(70.40%).The most common symptoms was fever reported from all cases followed by headache(74.60%),myalgia and anorexia(67.60%),back pain(59.20%) and chills(54.90%).DF represented(60.57%) of the cases while DHF represented(39.43%).About half of cases had underground water tanks for human use,5.60%had over house roof water tanks and 43.70%had both types,16.90% of these tanks were *** 70.00%of cases reported presence of small collection of water nearby houses and 46.80%reported the presence of mosquitoes within their ***:Most dengue fever cases might be endogenous in origin due to prevalence of mosquitoes and their breeding places within the houses and in nearby *** of mosquitoes and their breeding places will contribute to prevention of dengue fever.

关键词： Dengue fever(DF) Dengue haemorrhagic fever(DHF) Epidemiology Mosquitoes