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Hepatocardiorenal syndrome in liver cirrhosis:Recognition of a new entity?

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world Journal of Gastroenterology 2024年第2期30卷 128-136页

作者： henry H l wu Amina Rakisheva Arvind Ponnusamy Rajkumar Chinnadurai Renal Research Kolling Institute of Medical ResearchRoyal North Shore Hospital&The University of SydneySt.Leonards(Sydney)2065New South WalesAustralia Department of Cardiology City Cardiological CenterAlmaty 050000Kazakhstan Department of Renal Medicine Royal Preston HospitalPreston PR29HTUnited Kingdom Donal O’Donoghue Renal Research Centre&Department of Renal Medicine Northern Care Alliance National Health Service Foundation TrustSalford M68HDUnited Kingdom

Emerging evidence and perspectives have pointed towards the heart playing an important role in hepatorenal syndrome(HRS),outside of conventional understanding that liver cirrhosis is traditionally considered the sole origin of a cascade of pathophysiological mechanisms directly affecting the kidneys in this *** the absence of established heart disease,cirrhotic cardiomyopathy may occur more frequently in those with liver cirrhosis and kidney *** is a specific form of cardiac dysfunction characterized by blunted contractile responsiveness to stress stimuli and altered diastolic relaxation with electrophysiological *** the clinical description of these potential cardiac-related complications of the liver,the role of the heart has traditionally been an overlooked aspect of circulatory dysfunction in *** from a physiological sense,temporality(prior onset)of cardiorenal interactions in HRS and positive effects stemming from portosystemic shunting demonstrated an important role of the heart in the development and progression of kidney dysfunction in cirrhotic *** this review,we discuss current concepts surrounding how the heart may influence the development and progression of HRS,and the role of systemic inflammation and endothelial dysfunction causing circulatory dysfunction within this *** temporality of heart and kidney dysfunction in HRS will be *** a subgroup of patients who receive portosystemic shunting,the dynamics of cardiorenal interactions following treatment is *** research to determine the unknowns in this topic is anticipated,hopefully to further clarify the intricacies surrounding the liver-heart-kidney connection and improve strategies for management.

关键词： Hepatorenal syndrome Cardiorenal syndrome Cirrhosis Cardiac dysfunction Circulatory dysfunction

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混凝土自复位墙结构地震全过程损伤分析

建筑结构学报 2024年第2期45卷 189-204页

作者：鲁懿虬 henry Richard S 周颖 RODGERS Geoffrey w 杨群顾安琪同济大学土木工程学院上海200092 奥克兰大学土木与环境系新西兰奥克兰1010 坎特伯雷大学土木与自然资源工程系新西兰基督城8140

后张法预应力混凝土自复位墙是一种有效的可恢复功能结构。虽然自复位墙自身在地震中损伤较小,但其与周边构件的变形不协调可使结构损伤严重。为控制结构层面的损伤,设计了1个框架-自复位墙结构,对自复位墙底、梁柱节点、墙梁节点、墙-... 详细信息

后张法预应力混凝土自复位墙是一种有效的可恢复功能结构。虽然自复位墙自身在地震中损伤较小,但其与周边构件的变形不协调可使结构损伤严重。为控制结构层面的损伤,设计了1个框架-自复位墙结构,对自复位墙底、梁柱节点、墙梁节点、墙-基础连接、柱-基础连接以及墙-板连接开展损伤控制设计,并对设计的结构进行足尺振动台试验。结构共经历了39次不同设计工况下不同烈度的地震激励,峰值加速度最大达1.0g,位移角最大达3.3%。对结构在历次地震作用下整体、局部构件和节点的损伤发展进行全过程定量分析,结果表明:自复位墙-开槽梁结构在地震作用下的损伤能够得到有效控制,其中多遇、设防地震作用下结构基本无损伤,罕遇地震作用下墙底损伤仅限角部剥落且面积仅为400 cm2,楼板有开裂且裂缝最大仅为1.2 mm,梁端剥落可忽略;自复位墙-开槽梁结构可使整个结构在不同设计位移角下实现多遇、设防地震不坏,罕遇地震小修甚至不修的抗震性能目标;设计的连接方式解决了结构中构件之间的变形不协调问题,提高了自复位墙结构层面的可修复性。

关键词：自复位墙开槽梁墙板连接振动台试验结构损伤

Efficient fidelity estimation:alternative derivation and related applications

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Communications in Theoretical Physics 2024年第9期76卷 16-20页

作者： Diego S Starke Marcos l w Basso Jonas Maziero Physics Department Center for Natural and Exact SciencesFederal University of Santa MariaRoraima Avenue 1000Santa MariaRS97105-900Brazil Center for Natural and Human Sciences Federal University of ABCAvenue of the StatesSanto AndréSão Paulo09210-580Brazil

In[***.A 107012427(2023)],Baldwin and Jones prove that Uhlmann–Jozsa’s fidelity between two quantum statesρandσ,i.e.,F(ρ,σ)=(Tr√√ρσ√ρ)^(2),can be written in a simplified form as F(ρ,σ)=(Tr√ρσ)^(2).In this article,we give an alternative proof of this result,using a function power series expansion and the properties of the trace *** approach not only reinforces the validity of the simplified expression but also facilitates the exploration of novel dissimilarity functions for quantum states and more complex trace functions of density operators.

关键词： Ulhmann–Jozsa fidelity Rényi entropy efficient fidelity estimation Chebyshev polynomials

Survey of E-Commerce Modeling and Optimization Strategies

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Tsinghua Science and Technology 2005年第Z1期10卷 761-771页

作者： wANG Dingwei nuttle henry l.w. FANG Shu-Cherng School of Information Science and Engineering Northeastern University Shenyang 110004 China Department of Industrial Engineering North Carolina State University Raleigh NC 27695 USA Department of Industrial Engineering North Carolina State University Raleigh NC 27695 USA

Electronic commerce is impacting almost all commercial activities. The resulting emerging commercial activities bring with them many new modeling and optimization problems. This survey reviews pioneering works in this new area, covering topics in advertising strategy, web page design, automatic pricing, auction methods, brokerage strategy, and customer behavior analysis. Mathematical models for problems in these areas and their solution algorithms are discussed. In addition to presenting and commenting on these works, we also discuss possible extensions and related problems. The objective of this survey is to encourage more researchers to pay attention to this emerging area.

关键词： electronic commerce modeling and optimization advertising web link pricing auction brokerage customer behavior

Precipitation transformation pathway and mechanical behavior of nanoprecipitation strengthened Fe-Mn-Al-C-Ni austenitic low-density steel

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Journal of Materials Science & Technology 2024年第7期174卷 157-167页

作者： Y.F.An X.P.Chen l.Mei P.Ren D.wei w.Q.Cao College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Guangxi Engineering Research Center for Characteristic Metallic Powder Materials School of Electronic EngineeringGuangxi University of Science and TechnologyLiuzhou 545006China Central Iron&Steel Research Institute Beijing 100081China

Precipitation strengthening has been widely adopted in austenitic low-density steel owing to excellent hardened *** approach generally employs the coherentκ′carbides and non-coherent B2 *** the precipitation transformation pathway is decisive for further optimizing the microstructures under specific engineering ***,the detailed precipitation sequence of Fe-28Mn-11Al-1C-5Ni(wt%)austenitic low-density steel as well as its influence on mechanical prop-erties during aging process is systematically *** results reveal that nano-sizedκ′carbides domains(2 nm)exist in the solution-treated *** aging at 500℃for 1 h,the cuboidalκ′carbides(15-20 nm)uniformly disperse in austenite ***,after aging at 700℃for 15 min,the coarsenκ′carbides(30-35 nm)inhomogeneously distribute and align preferentially along the〈100〉***,extending the aging time to 60 min,the needle-type B2 particles replace theκ′carbides due to the enrichment of Ni elements at the phase boundaries among the austenite andκ′*** aging at 900℃,κ′carbides entirely dissolve into the austenite matrix,and the intragranular B2 particles are the sole precipitates in the austenite matrix and follow the K-S orientation relationship with *** work hardening capability seriously deteriorates due to the shearing ofκ′carbides by gliding *** the intragranular B2 particles preserve excellent work hardening rate by dislocations bow-out *** present work is meaningful for guiding the design of new generation dual-nano precipitation austenitic lightweight steel.

关键词： lightweight steel κ′-carbides B2 particles work hardening capability

Precipitation of multi-type nano-quasicrystals in a Mg-Zn-Y alloy

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Journal of Magnesium and Alloys 2024年第3期12卷 997-1008页

作者： w.Z.wang X.Z.Zhou l.F.Zhang H.Q.Ye Z.Q.Yang Shenyang National laboratory for Materials Science Institute of Metal ResearchChinese Academy of ScienceShenyang 110016China Ji Hua laboratory Foshan 528251China Foshan University Foshan 528231China

Mg-6Zn-1Y(at.%)ribbons with strengthening precipitates of multi-type nanoquasicrystals were prepared by melt-spinning followed by aging *** evolution of the rapidly solidified ribbons during isothermal aging was comprehensively studied using various electron microscopy *** new kinds of decagonal quasicrystals were formed in aged ribbons,in addition to precipitation of nanometer icosahedral ***-resolution observations reveal that both decagonal quasicrystals can be modeled by quasiperiodic tiling with decagonal clusters of 2.5 nm in diameter,but overlap of neighboring clusters in both decagonal quasicrystals is different from the Gummelt model observed in other quasicrystals.A shell composed of complex laves Mg-Zn domains was formed surrounding each decagonal quasicrystal precipitate upon prolonged *** addition,all kinds of nanoprecipitates exhibit excellent structure and size stability at 573 *** findings may have implications for not only fundamental studies about quasicrystals,but also microstructural manipulation of high-performance Mg alloys.

关键词： Quasicrystal Mg alloys Rapid solidification Scanning-transmission electron microscopy.

Anneal-free ultra-low loss silicon nitride integrated photonics

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light(Science & Applications) 2024年第8期13卷 1565-1577页

作者： Debapam Bose Mark w.Harrington Andrei Isichenko Kaikai liu Jiawei wang Nitesh Chauhan Zachary l.Newman Daniel J.Blumenthal Department of Electrical and Computer Engineering University of California Santa BarbaraSanta BarbaraCA 93106USA Octave Photonics LouisvilleCO 80027USA

Heterogeneous and monolithic integration of the versatile low-loss silicon nitride platform with low-temperature materials such as silicon electronics and photonics,III–V compound semiconductors,lithium niobate,organics,and glasses has been inhibited by the need for high-temperature annealing as well as the need for different process flows for thin and thick *** techniques are needed to maintain the state-of-the-art losses,nonlinear properties,and CMOS-compatible processes while enabling this next generation of 3D silicon nitride *** report a significant advance in silicon nitride integrated photonics,demonstrating the lowest losses to date for an anneal-free process at a maximum temperature 250℃,with the same deuterated silane based fabrication flow,for nitride and oxide,for an order of magnitude range in nitride thickness without requiring stress mitigation or *** report record low anneal-free losses for both nitride core and oxide cladding,enabling 1.77 dBm^(-1) loss and 14.9 million Q for 80 nm nitride core waveguides,more than half an order magnitude lower loss than previously reported sub 300℃ *** 800 nm-thick nitride,we achieve as good as 8.66 dBm^(-1) loss and 4.03 million Q,the highest reported Q for a low temperature processed resonator with equivalent device area,with a median of loss and Q of 13.9 dBm^(-1) and 2.59 million each *** demonstrate laser stabilization with over 4 orders of magnitude frequency noise reduction using a thin nitride reference cavity,and using a thick nitride micro-resonator we demonstrate OPO,over two octave supercontinuum generation,and four-wave mixing and parametric gain with the lowest reported optical parametric oscillation threshold per unit resonator *** results represent a significant step towards a uniform ultra-low loss silicon nitride homogeneous and heterogeneous platform for both thin and thick waveguides capable of linear and nonlinear photonic circuits and

关键词： resonator thick free

Optimization of bio-oil production parameters from the pyrolysis of elephant grass (Pennisetum purpureum) using response surface methodology

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Clean Energy 2024年第5期8卷 241-251页

作者： Sunday C.Ikpeseni Samuel O.Sada Ufuoma J.Efetobor henry O.Orugba Mathias Ekpu Hilary I.Owamah Jeremiah l.Chukwuneke Solomon Oyebisi Uche P.Onochie Department of Mechanical Engineering Delta State UniversityP.M.B.1AbrakaNigeria Department of Mechanical Engineering Delta State PolytechnicP.M.B.3Otefe-OgharaNigeria Department of Chemical Engineering Delta State UniversityP.M.B.1AbrakaNigeria Department of Civil Engineering Delta State UniversityP.M.B.1AbrakaNigeria Department of Mechanical Engineering Nnamdi Azikiwe UniversityP.M.B.2025AwkaNigeria Department of Civil Engineering Covenant UniversityP.M.B.1023OttaNigeria Department of Civil Engineering The University of the South PacificP.M.B.9072SuvaFiji Department of Mechanical Engineering Delta State University of Science and TechnologyP.M.B.5OzoroNigeria

The need to increase bio-oil yield from biomass and enhance its fuel properties has driven research into optimizing the pyrolysis *** study investigated the influence of three key process parameters—temperature,heating rate,and nitrogen flow rate—on the pyrolysis of elephant grass(Pennisetum purpureum)in a fixed-bed *** surface methodology was used to study the im-pact of the aforementioned variables on bio-oil yield to improve its production *** analysis of the biomass revealed 79.24 wt%volatile matter,14.22 wt%fixed carbon,and 5.86%ash,with ultimate analysis showing 45.44%carbon,5.59%hydrogen,and 40.95%*** high volatile matter content and favourable carbon and hydrogen percentages indicate that elephant grass is a vi-able energy source due to its potential for high bio-oil yield and energy *** resulting bio-oil exhibited a higher heating value of 20.9 MJ/kg,indicating its suitability for various heating applications.A second-order regression model was developed for bio-oil yield,with optimal conditions identified as a temperature of 550°C,a heating rate of 17°C/min,and a nitrogen flow rate of 6 ml/*** study achieved an optimal bio-oil yield of 59.03 wt%,and the model’s high R²value of 0.8683 from analysis of variance analysis confirmed its predictive *** research highlights elephant grass as a sustainable feedstock for bio-oil production,offering valuable insights into optimizing pyrolysis conditions to enhance bio-oil yield,thus advancing biofuel technology.

关键词： renewable energy biomass sustainable feedstock regression model fixed-bed reactor

Reducing strain on primary healthcare systems through innovative models of care:the impact of direct access physiotherapy for musculoskeletal conditions—an interrupted time series analysis

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Family Medicine and Community Health 2024年第3期12卷 1-12页

作者： James henry Zouch Bjørnar Berg Are Hugo Pripp Kjersti Storheim Claire E Ashton-James Manuela l Ferreira Margreth Grotle Paulo H Ferreira Sydney Musculoskeletal Health Faculty of Medicine and HealthThe University of SydneySydneyNew South WalesAustralia Centre for Intelligent Musculoskeletal Health Oslo Metropolitan University Faculty of Health SciencesOsloNorway Oslo Metropolitan University Faculty of Health Sciences OsloNorway Oslo Centre of Biostatistics and Epidemiology Oslo University HospitalOsloNorway Department of Rehabilitation Science and Health Technology Oslo Metropolitan University Faculty of Health SciencesOsloNorway Department of Research and Innovation Oslo University Hospital Division of Clinical NeuroscienceOsloNorway Sydney Medical School Kolling InstituteThe University of Sydney Faculty of Medicine and HealthSydneyNew South WalesAustralia The George Institute for Global Health SydneyNew South WalesAustralia Department of Research and Innovation Oslo University HospitalOsloNorway Department of Rehabilitation and Technology Oslo Metropolitan University Faculty of Health SciencesOsloNorway Charles Perkins Centre Sydney Musculoskeletal HealthThe University of Sydney Faculty of Medicine and HealthSydneyNew South WalesAustralia

Objectives To evaluate the longitudinal impact of introducing a national,direct access physiotherapy model of care on the rates of primary and secondary care consultations for musculoskeletal(MSK)*** Interrupted time series analysis using segmented linear *** Norway primary care Participants A cohort of 82072 participants was derived from 3 population-based health surveys conducted across separate geographical regions in *** participants surveyed were eligible for inclusion as a national representative sample of the Norwegian *** MSK consultations were linked to the Norwegian Control and Payment of Health Reimbursement database and the Norwegian Patient Register using the International Classification of Primary Care diagnostic medical codes l-chapter for MSK conditions and spine related International Classification of Diseases,10th Revision,*** Direct access to physiotherapy model of care introduced nationally in Norway in *** model allowed Norwegians to consult directly with qualified physiotherapists for MSK conditions(eg,back pain,knee osteoarthritis)without the need for a medical referral in order to claim a social security *** outcomes measured Rates of primary care consultations per 10000 population(general practitioner(GP)and physiotherapist consultations)and secondary care(specialist consultations and surgical procedures)measured from 2014 to *** The introduction of the direct access physiotherapy model was associated with an immediate stepped reduction of 391 general practice consultations per 10000 population,(95%CI:−564 to−216),without an associated change in physiotherapy *** analyses suggested there was an associated reduction in physiotherapy consultations for those in the lowest education group of 150 consultations per quarter(95%CI:−203 to−97),70 consultations per quarter in the intermediate education group(95%CI:−115 to−27)and a step

关键词： impact analysis strain